Methylcholanthrene

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1 Diseases Researched for Methylcholanthrene
NameACCKFocus
Cancers: All11Locked

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1 Abstracts with Methylcholanthrene Research

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Pubmed Data : Cancer Cell Int. 2010;10:4. Epub 2010 Feb 23. PMID: 20178601
Study Type : Commentary
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Diseases : Cancers: All
Additional Keywords : Cellular Immortalization

Methylcholanthrene (MCA) is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures[clarification needed]. It is a yellow solid with a melting pont around 180 °C. Methylcholanthrene is used in laboratory studies of chemical carcinogenesis. It is an alkylated derivative of benz[a]anthracene and has a similar UV spectrum. The most common isomer is 3-methylcholanthrene, although the methyl group can occur in other places.

3-Methylcholanthrene, a known carcinogen which builds up in the prostate due to cholesterol breakdown, is implicated in prostate cancer.[citation needed] It "readily produces" primary sarcomas in mice.[1]

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