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6 Diseases Researched for Cobalt

Name	AC	CK
Oxidative Stress	1	2
Breast Cancer	1	1
Cancers: Estrogen Responsive	1	1
Estrogen Dominance	1	1
Heavy Metal Toxicity	1	1
Hypoxia	1	1

1 Adverse Pharmacological Actions Researched for Cobalt

Name	AC	CK	Focus
Estrogenic	2	2

Research Articles 4
Cumulative Knowledge Score 6
Overall Research Rating GOOD

View the Evidence:
7 Abstracts with Cobalt Research

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Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats.Dec 31, 2018

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Pubmed Data : Neurotoxicology. 2019 09 ;74:252-263. Epub 2019 Jul 27. PMID: 31362009

Article Published Date : Dec 31, 2018

Study Type : Animal Study

Additional Links

Substances : Gallic Acid, Luteolin

Diseases : Cognitive Decline/Dysfunction

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Problem Substances : Cobalt

[+]

Quercetin and vitamin C mitigate cobalt chloride-induced hypertension. Jun 09, 2016

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Pubmed Data : Biol Trace Elem Res. 2016 Jun 10. Epub 2016 Jun 10. PMID: 27283837

Article Published Date : Jun 09, 2016

Study Type : Animal Study

Additional Links

Substances : Quercetin, Vitamin C

Diseases : Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor

Problem Substances : Cobalt

[+]

A wide range of metals have been identified to have estrogenic properties.May 01, 2006

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Pubmed Data : J Appl Toxicol. 2006 May-Jun;26(3):191-7. PMID: 16489580

Article Published Date : May 01, 2006

Study Type : Review

Additional Links

Diseases : Cancers: Estrogen Responsive, Estrogen Dominance, Heavy Metal Toxicity

Additional Keywords : Metalloestrogens

Problem Substances : Aluminum, Antimony, Arsenite, Barium, Cadmium, Chromium Chloride, Cobalt, Industrial Copper (inorganic), Lead, Mercury, Selenite, Tin, Vanadate

Adverse Pharmacological Actions : Estrogenic

[+]

Astaxanthin mitigated cobalt cytotoxicity in the MG-63 cells by modulating the oxidative stress.Jul 23, 2017

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : BMC Pharmacol Toxicol. 2017 Jul 24 ;18(1):58. Epub 2017 Jul 24. PMID: 28738843

Article Published Date : Jul 23, 2017

Study Type : In Vitro Study

Additional Links

Substances : Astaxanthin

Pharmacological Actions : Antioxidants

Problem Substances : Cobalt

[+]

Estrogen-like activity of metals in MCF-7 breast cancer cells.May 31, 2003

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Endocrinology. 2003 Jun ;144(6):2425-36. PMID: 12746304

Article Published Date : May 31, 2003

Study Type : In Vitro Study

Additional Links

Diseases : Breast Cancer

Pharmacological Actions : Estrogen Receptor Modulators

Additional Keywords : Metalloestrogens

Problem Substances : Cobalt, Industrial Copper (inorganic), Lead, Nickel, unspecified type, Tin

Adverse Pharmacological Actions : Estrogenic

[+]

These results support the use of aged garlic extract and S-allylcysteine as a therapeutic alternative for hypoxic conditions.Dec 31, 2015

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Article Publish Status : This is a free article. Click here to read the complete article.

Pubmed Data : Biol Res. 2016 ;49(1):7. Epub 2016 Feb 1. PMID: 26830333

Article Published Date : Dec 31, 2015

Study Type : In Vitro Study

Additional Links

Substances : Garlic: Aged

Diseases : Hypoxia

Pharmacological Actions : Anti-Apoptotic, Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor

Problem Substances : Cobalt

[+]

Thymoquinone protects against cobalt chloride-induced neurotoxicity.Sep 30, 2017

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Pubmed Data : J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):843-853. PMID: 29254287

Article Published Date : Sep 30, 2017

Study Type : In Vitro Study

Additional Links

Substances : Thymoquinone

Diseases : Neurodegenerative Diseases

Pharmacological Actions : Antioxidants, Neuroprotective Agents, Nrf2 activation

Additional Keywords : Antioxidants, Cobalt, Neurodegenerative diseases, Neuroprotective Agents, Nrf2 activation, thymoquinone

Problem Substances : Cobalt

Cobalt Related Articles

Metalloestrogens: A New Class Of Cancer Causing Estrogens

Written by Sayer Ji, Founder

We are now increasingly being exposed to an emerging class of “metalloestrogens” in our food, supplements and environment with the potential to add to the estrogenic burden of the human breast.

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This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

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Focus Your Research

Click any topic below to filter + focus research

View the Evidence: 7 Abstracts with Cobalt Research

Limited to Members Only

Currently Available Sorting Options

Neuroprotection by luteolin and gallic acid against cobalt chloride-induced behavioural, morphological and neurochemical alterations in Wistar rats.Dec 31, 2018

Click here to read the entire abstract

Quercetin and vitamin C mitigate cobalt chloride-induced hypertension. Jun 09, 2016

Click here to read the entire abstract

A wide range of metals have been identified to have estrogenic properties.May 01, 2006

Click here to read the entire abstract

Astaxanthin mitigated cobalt cytotoxicity in the MG-63 cells by modulating the oxidative stress.Jul 23, 2017

Click here to read the entire abstract

Estrogen-like activity of metals in MCF-7 breast cancer cells.May 31, 2003

Click here to read the entire abstract

These results support the use of aged garlic extract and S-allylcysteine as a therapeutic alternative for hypoxic conditions.Dec 31, 2015

Click here to read the entire abstract

Thymoquinone protects against cobalt chloride-induced neurotoxicity.Sep 30, 2017

Click here to read the entire abstract

Cobalt Related Articles

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Cobalt

View the Evidence:
7 Abstracts with Cobalt Research