Aluminum

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82 Diseases Researched for Aluminum
NameACCKFocus
Aluminum Toxicity 111284Locked
Vaccine-induced Toxicity 2579Locked
Macrophagic myofasciitis 1474Locked
Autism Spectrum Disorders950Locked
Breast Cancer637Locked
Heavy Metal Toxicity536Locked
Oxidative Stress1332Locked
Alzheimer's Disease1631Locked
Neurodegenerative Diseases1726Locked
Autism321Locked
Brain Inflammation 921Locked
Autoimmune Diseases717Locked
Cognitive Decline/Dysfunction416Locked
Inflammation616Locked
Gulf War Syndrome313Locked
Infant Chemical Exposures211Locked
Atherosclerosis110Locked
Brain: Oxidative Stress510Locked
C-Reactive Protein110Locked
Clostridium Infections110Locked
Diarrhea110Locked
High Cholesterol110Locked
Hypothyroidism110Locked
Immune Dysregulation: TH1/TH2 imbalance110Locked
Infant Mortality 110Locked
Intima Media Thickening 110Locked
Low Immune Function: Natural Killer Cells110Locked
Premature Birth110Locked
Memory Disorders48Locked
Multiple Sclerosis37Locked
Acrylamide-induced toxicity36Locked
Dementia26Locked
Prenatal Chemical Exposures26Locked
Aging35Locked
Breast Cancer: Triple Negative 15Locked
Cancer Metastasis15Locked
Chemically-Induced Liver Damage24Locked
Chronic Fatigue Syndrome24Locked
Fluoride Toxicity 24Locked
Lipid Peroxidation24Locked
Autoimmune/inflammatory syndrome induced by adjuvants (ASIA)33Locked
Central Nervous System Diseases13Locked
Pseudolymphoma13Locked
Amyotrophic lateral sclerosis (ALS)12Locked
Anxiety Disorders12Locked
Chemotherapy-Induced Toxicity: Oxaliplatin12Locked
Colitis12Locked
DNA damage12Locked
Dysbiosis12Locked
High Fat Diet12Locked
Infertility: Male12Locked
Inflammatory Bowel Diseases12Locked
Kidney Damage: Chemically-Induced12Locked
Lipopolysaccharide-Induced Toxicity12Locked
Liver Damage12Locked
Motor Neuron Disease12Locked
Neuropathic Pain12Locked
Osteoporosis12Locked
Peripheral Neuropathies12Locked
Sjogren's Syndrome12Locked
Social Behavior12Locked
Systemic Lupus Erythematosus12Locked
Testicular Injury: Chemical/Metal Induced12Locked
Uremia12Locked
Wound Healing12Locked
Attention Deficit Disorder11Locked
Benzo[a]pyrene-induced Toxicity 11Locked
Bipolar Disorder11Locked
Bisphenol Toxicity11Locked
Cancers: Estrogen Responsive11Locked
Crohn's Disease11Locked
Estrogen Dominance11Locked
Febrile Seizures11Locked
Fibromyalgia11Locked
Guillain-Barre Syndrome11Locked
Infant Nutrition: Infant Formula11Locked
Lymphoma11Locked
Myopathies11Locked
Neurodevelopmental Disorders11Locked
New Variant Creutzfeldt-Jakob Disease11Locked
Parkinson's Disease11Locked
Prostate Cancer11Locked
17 Adverse Pharmacological Actions Researched for Aluminum
NameACCKFocus
Neurotoxic2772Locked
Immunotoxic415Locked
Inflammatory713Locked
Cardiotoxic212Locked
Endocrine Disruptor211Locked
Immunosuppressive211Locked
Genotoxic24Locked
Hematoxic12Locked
Hepatotoxic12Locked
Hypertensive12Locked
Apoptotic11Locked
Carcinogenic11Locked
Cytotoxic11Locked
Estrogenic11Locked
Hemolytic11Locked
Hypermethylation11Locked
Irritant11Locked
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View the Evidence:
263 Abstracts with Aluminum Research

[+]

Chronic exposure to aluminum is associated with increased risk of Alzheimer's disease.Jan 01, 2016

Pubmed Data : Neurosci Lett. 2016 Jan 1 ;610:200-6. Epub 2015 Nov 27. PMID: 26592479
Article Published Date : Jan 01, 2016
Study Type : Meta Analysis
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This meta-analysis shows that the data available on the safety of aluminum adjuvants is severely lacking. There is also only data available for aluminum hydroxide and does not consider the toxicity of amorphous aluminum hydroxyphosphate.Feb 01, 2004

Pubmed Data : Lancet Infect Dis. 2004 Feb ;4(2):84-90. PMID: 14871632
Article Published Date : Feb 01, 2004
Study Type : Meta Analysis
Additional Links
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

"Circulating levels of metals are related to carotid atherosclerosis in elderly."Dec 15, 2011

Pubmed Data : Sci Total Environ. 2011 Dec 15. Epub 2011 Dec 15. PMID: 22178028
Article Published Date : Dec 15, 2011
Study Type : Human Study
Additional Links
Diseases : Atherosclerosis, Intima Media Thickening
Problem Substances : Aluminum
Adverse Pharmacological Actions : Cardiotoxic
[+]

A number of commonly used drugs interfere with the absorption of levothyroxine. Dec 01, 2009

Pubmed Data : Best Pract Res Clin Endocrinol Metab. 2009 Dec;23(6):781-92. PMID: 19942153
Article Published Date : Dec 01, 2009
Study Type : Human Study
Additional Links
Diseases : Hypothyroidism
Problem Substances : Antacids: Aluminium-Containing, Bile Acid Sequestrants, Calcium Carbonate, Ferrous Sulphate, Phosphate Binders, Proton-Pump Inhibitors, Raloxifene, Sucralfate
[+]

Administration of 240 mg of anthocyanins a day for 30 days caused a substantial increase of glutathione peroxidase and catalase activities. While decreasing the lead, aluminum and cooper concentrations.Oct 31, 2005

Pubmed Data : Pol Merkur Lekarski. 2005 Nov ;19(113):651-3. PMID: 16498804
Article Published Date : Oct 31, 2005
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Chokeberry
Diseases : High Cholesterol, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Detoxification, Phytotherapy
Problem Substances : Aluminum, Lead
[+]

Aluminium content is higher in nipple aspirate fluid of breast cancer-affected women versus healthy controls. Apr 01, 2011

Pubmed Data : J Appl Toxicol. 2011 Apr ;31(3):262-9. Epub 2011 Feb 21. PMID: 21337589
Article Published Date : Apr 01, 2011
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer, Heavy Metal Toxicity
Problem Substances : Aluminum, Antiperspirants
[+]

Aluminium in brain tissue in familial Alzheimer's disease.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trace Elem Med Biol. 2017 Mar ;40:30-36. Epub 2016 Dec 9. PMID: 28159219
Article Published Date : Feb 28, 2017
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
[+]

Aluminium is found in human breast tissue and may be connected to breast cancer incidence. Sep 01, 2007

Pubmed Data : J Inorg Biochem. 2007 Sep ;101(9):1344-6. Epub 2007 Jun 12. PMID: 17629949
Article Published Date : Sep 01, 2007
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer
Problem Substances : Aluminum
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Aluminium, carbonyls and cytokines in human nipple aspirate fluids: Possible relationship between inflammation, oxidative stress and breast cancer microenvironment.Jul 11, 2013

Pubmed Data : J Inorg Biochem. 2013 Jul 12. Epub 2013 Jul 12. PMID: 23916117
Article Published Date : Jul 11, 2013
Study Type : Human Study
Additional Links
Diseases : Breast Cancer
Problem Substances : Aluminum
[+]

Aluminum can be distributed to the brain both in patients with renal insufficiency and healthy controls. Dec 01, 1987

Pubmed Data : J Trace Elem Electrolytes Health Dis. 1987 Dec ;1(2):69-72. PMID: 2856571
Article Published Date : Dec 01, 1987
Study Type : Human Study
Additional Links
Diseases : Kidney Failure: Chronic
Additional Keywords : Vaccine Research
Problem Substances : Aluminum, Antacids: Aluminium-Containing
[+]

Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.Nov 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inorg Biochem. 2009 Nov;103(11):1555-62. Epub 2009 Aug 20. PMID: 19740540
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Diseases : Gulf War Syndrome
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum hydroxide-induced macrophagic myofasciitis (MMF) associated with vaccination has been reported. Nov 01, 2011

Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1457-63. Epub 2011 Aug 22. PMID: 22099155
Article Published Date : Nov 01, 2011
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Aluminum vaccine adjuvants appear to contribute to the rising prevalence of autism.Nov 01, 2011

Pubmed Data : J Inorg Biochem. 2011 Nov ;105(11):1489-99. Epub 2011 Aug 23. PMID: 22099159
Article Published Date : Nov 01, 2011
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Immunotoxic, Neurotoxic
[+]

Association of serum aluminum levels with mortality in patients on chronic hemodialysis.Nov 12, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2018 Nov 13 ;8(1):16729. Epub 2018 Nov 13. PMID: 30425257
Article Published Date : Nov 12, 2018
Study Type : Human Study
Additional Links
Diseases : All-Cause Mortality, Aluminum Toxicity , Hemodialysis
Additional Keywords : Increased Risk
Problem Substances : Aluminum
[+]

Breastfed infants in Brazil receiving a full recommended schedule of immunizations showed an exceedingly high exposure of Al (225 to 1750 μg per dose) when compared with estimated levels absorbed from breast milk.Nov 01, 2010

Pubmed Data : J Expo Sci Environ Epidemiol. 2010 Nov ;20(7):598-601. Epub 2009 Dec 16. PMID: 20010978
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Diseases : Heavy Metal Toxicity
Therapeutic Actions : Breastfeeding
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Hair mercury levels in ASD patients were more than 3-fold and 2-fold higher as compared to the controls and children with catatonia in ASD.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jan ;109:174-180. Epub 2018 Nov 2. PMID: 30396074
Article Published Date : Dec 31, 2018
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Heavy Metal Toxicity
Problem Substances : Aluminum, Mercury
[+]

In the present study, intracytoplasmic inclusions were constantly detected in macrophages of the MMF lesions and were shown to contain aluminium by three different methods.Aug 31, 2001

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Brain. 2001 Sep ;124(Pt 9):1821-31. PMID: 11522584
Article Published Date : Aug 31, 2001
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Macrophagic myofasciitis
Additional Keywords : Biopersistence
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B, Vaccination: Tetanus
Problem Substances : Aluminum Hydroxide
[+]

Increased aluminum content in certain brain structures is correlated with higher silicon concentration in alcoholic use disorder.May 02, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 3 ;24(9). Epub 2019 May 3. PMID: 31058813
Article Published Date : May 02, 2019
Study Type : Human Study
Additional Links
Diseases : Alcohol Toxicity , Aluminum Toxicity , Neurodegenerative Diseases
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum
[+]

Intramuscular injection of alum-containing vaccine was associated with the appearance of aluminum deposits in distant organs.Apr 03, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Med. 2013 Apr 4 ;11:99. Epub 2013 Apr 4. PMID: 23557144
Article Published Date : Apr 03, 2013
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Lead and mercury negatively affect infant milestones like walking and talking.Apr 01, 2014

Pubmed Data : Environ Pollut. 2014 Apr ;187:130-5. Epub 2014 Jan 28. PMID: 24486466
Article Published Date : Apr 01, 2014
Study Type : Human Study
Additional Links
Diseases : Mercury Poisoning
Additional Keywords : breastfeeding, Infant Body Burden, infant health
Problem Substances : Aluminum, Lead, Mercury
Adverse Pharmacological Actions : Neurotoxic
[+]

Levels of mercury, lead, and aluminum in the hair of autistic children are higher than controls.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Behav Neurol. 2015 ;2015:545674. Epub 2015 Oct 5. PMID: 26508811
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders
Problem Substances : Aluminum, Lead, Mercury
[+]

Long-term persistence of vaccine-derived aluminum hydroxide within the body assessed by MMF is associated with cognitive dysfunction.Oct 31, 2009

Pubmed Data : J Inorg Biochem. 2009 Nov ;103(11):1571-8. Epub 2009 Aug 20. PMID: 19748679
Article Published Date : Oct 31, 2009
Study Type : Human Study
Additional Links
Diseases : Cognitive Decline/Dysfunction, Macrophagic myofasciitis
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
[+]

Macrophagic myofasciitis in children is a localized reaction to vaccination.May 31, 2008

Pubmed Data : J Child Neurol. 2008 Jun ;23(6):614-9. Epub 2008 Feb 15. PMID: 18281624
Article Published Date : May 31, 2008
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Parenteral nutrition formulas for neonates have potentially toxic levels of aluminum.Feb 01, 2010

Pubmed Data : J Pediatr Gastroenterol Nutr. 2010 Feb;50(2):208-11. PMID: 20038851
Article Published Date : Feb 01, 2010
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Infant Chemical Exposures, Premature Birth
Problem Substances : Aluminum, Parenteral Nutrition: Infant
[+]

Selective accumulation of aluminum in cerebral arteries in Alzheimer's disease.Aug 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Inorg Biochem. 2013 Sep ;126:35-7. Epub 2013 May 21. PMID: 23764827
Article Published Date : Aug 31, 2013
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease
Problem Substances : Aluminum
[+]

The association with DTwP vaccines and increased infant mortality in females may be due to vaccine adjuvants and Th2 polarizing effects.Jan 01, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trop Med. 2011 ;2011:706304. Epub 2011 May 5. PMID: 21760811
Article Published Date : Jan 01, 2011
Study Type : Human Study
Additional Links
Diseases : Immune Dysregulation: TH1/TH2 imbalance, Infant Mortality , Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: Pertussis, Vaccination: Tetanus, Vaccinaton: Diptheria
Problem Substances : Adjuvant, Aluminum Hydroxide, Vaccine Adjuvants
[+]

The brain aluminium content is extraordinarily high in people with autism. Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Trace Elem Med Biol. 2018 Mar ;46:76-82. Epub 2017 Nov 26. PMID: 29413113
Article Published Date : Feb 28, 2018
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Autism
Problem Substances : Aluminum
[+]

The CDC's safety data for aluminum adjuvant safety in infants is based on the pharmacokinetics of a non-adjuvant aluminum compound in one adult male.Nov 28, 2011

Pubmed Data : Vaccine. 2011 Nov 28 ;29(51):9538-43. Epub 2011 Oct 11. PMID: 22001122
Article Published Date : Nov 28, 2011
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

The results suggest that aluminum-induced CRP may in part contribute to a pathophysiological state associated with a chronic systemic inflammation of the human vasculature.Jul 31, 2015

Pubmed Data : J Inorg Biochem. 2015 Aug 1. Epub 2015 Aug 1. PMID: 26265215
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Diseases : Brain Inflammation , C-Reactive Protein, Inflammation
Additional Keywords : Increased Risk
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

The use of acid-suppressive therapy, particularly proton pump inhibitors, and NSAIDs are associated with an increased risk of community-acquired C difficile.Dec 21, 2005

Pubmed Data : JAMA. 2005 Dec 21;294(23):2989-95. PMID: 16414946
Article Published Date : Dec 21, 2005
Study Type : Human Study
Additional Links
Diseases : Clostridium Infections, Diarrhea, Low Immune Function: Natural Killer Cells
Problem Substances : Antacids: Aluminium-Containing, Histamine Receptor Antagonists, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Adverse Pharmacological Actions : Immunosuppressive
[+]

The use of aluminum utensils for cooking meals is associated with chronic aluminum toxicity.Mar 31, 2019

Pubmed Data : J Assoc Physicians India. 2019 Apr ;67(4):52-56. PMID: 31309799
Article Published Date : Mar 31, 2019
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Kidney Failure: Chronic
Additional Keywords : Increased Risk
Problem Substances : Aluminum
[+]

The vaccines containing the adjuvant aluminium hydroxide may trigger macrophagic myofasciitis in some patients.Dec 31, 2014

Pubmed Data : Rheumatol Int. 2015 Jan ;35(1):189-92. Epub 2014 Jun 13. PMID: 24923906
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

These results provide a neurobiological substrate for brain dysfunction in aluminum hydroxide adjuvant-induced macrophagic myofasciitis patients.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0128353. Epub 2015 Jun 1. PMID: 26030650
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

This data supports the historic evidence that heavy metals play a role in the development of ASD.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Maedica (Buchar). 2012 Jan ;7(1):38-48. PMID: 23118818
Article Published Date : Dec 31, 2011
Study Type : Human Study
Additional Links
Diseases : Autism Spectrum Disorders, Heavy Metal Toxicity
Problem Substances : Aluminum, Cadmium, Mercury
[+]

This study demonstrates a significant positive association between the severity of autism and the relative body burden of toxic metals.Jan 01, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2009 ;2009:532640. Epub 2009 Aug 26. PMID: 20107587
Article Published Date : Jan 01, 2009
Study Type : Human Study
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Additional Keywords : heavy metal toxicity
Problem Substances : Aluminum, Heavy Metals, Lead, Mercury
[+]

This study is the only study examining changes in serum and urinary levels of aluminum in 15 infants after a routine 2-month vaccination. The data for the post-vacc measurements are missing.Sep 01, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : JAMA Pediatr. 2013 Sep ;167(9):870-2. PMID: 23856981
Article Published Date : Sep 01, 2013
Study Type : Human Study
Additional Links
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Up-to-date children were exposed to 11-26% more aluminum from vaccines than undervaccinated children between 2004 and 2011.Nov 26, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Vaccine. 2015 Nov 27 ;33(48):6736-44. Epub 2015 Oct 27. PMID: 26518400
Article Published Date : Nov 26, 2015
Study Type : Human Study
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Using morin stain, this study demonstrates that macrophagic myofasciitis (mostly pediatric) patient's macrophages test positive for aluminum.Jan 01, 2017

Pubmed Data : J Neuropathol Exp Neurol. 2017 04 1 ;76(4):323-331. PMID: 28340105
Article Published Date : Jan 01, 2017
Study Type : Human Study
Additional Links
Diseases : Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Aluminum could increase the migration of human breast cancer cells irrespective of their oestrogen responsiveness.Sep 07, 2015

Pubmed Data : J Inorg Biochem. 2015 Sep 8. Epub 2015 Sep 8. PMID: 26365320
Article Published Date : Sep 07, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer, Breast Cancer: Triple Negative , Cancer Metastasis
Additional Keywords : Risk Factors
Problem Substances : Aluminum, Aluminum Chloride, Antiperspirants
[+]

Aluminum hydroxide-stimulated macrophages contain large and persistent intracellular crystalline inclusions.Aug 13, 2004

Pubmed Data : Vaccine. 2004 Aug 13 ;22(23-24):3127-35. PMID: 15297065
Article Published Date : Aug 13, 2004
Study Type : Human In Vitro
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminum in neurological and neurodegenerative disease.Jan 30, 2019

Pubmed Data : Mol Neurobiol. 2019 Jan 31. Epub 2019 Jan 31. PMID: 30706368
Article Published Date : Jan 30, 2019
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity , Autism Spectrum Disorders, Dementia, Neurodegenerative Diseases
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Aluminum induces inflammatory and proteolytic alterations in human monocytic cell line.Sep 20, 2015

Pubmed Data : J Inorg Biochem. 2015 Sep 21. Epub 2015 Sep 21. PMID: 26421828
Article Published Date : Sep 20, 2015
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Aluminum Chloride
Adverse Pharmacological Actions : Inflammatory
[+]

Aluminum nanoparticles are genotoxic in vitro.Feb 01, 2016

Pubmed Data : J Biomed Mater Res B Appl Biomater. 2016 Feb ;104(2):241-52. Epub 2015 Feb 26. PMID: 25715832
Article Published Date : Feb 01, 2016
Study Type : Human In Vitro
Additional Links
Diseases : DNA damage
Anti Therapeutic Actions : Nanotechnology, Vaccination: All
Problem Substances : Aluminum, Aluminum oxide
Adverse Pharmacological Actions : Genotoxic
[+]

Most human placental samples contain aluminum. Aug 31, 2010

Pubmed Data : Metallomics. 2010 Sep ;2(9):621-7. Epub 2010 Aug 17. PMID: 21072353
Article Published Date : Aug 31, 2010
Study Type : Human In Vitro
Additional Links
Diseases : Aluminum Toxicity , Heavy Metal Toxicity, Prenatal Chemical Exposures
Problem Substances : Aluminum
[+]

NP concentrations over 200 μg/mL are large enough to induce cytotoxic and genotoxic effects to cells.May 01, 2015

Pubmed Data : Dent Mater. 2015 May ;31(5):556-64. Epub 2015 Mar 6. PMID: 25749564
Article Published Date : May 01, 2015
Study Type : Human In Vitro
Additional Links
Diseases : DNA damage
Anti Therapeutic Actions : Nanotechnology
Problem Substances : Aluminum, Nanoparticles
Adverse Pharmacological Actions : Cytotoxic, Genotoxic
[+]

Thimerosal at low nanomolar concentrations was able to induce significant cellular toxicity in human neuron and fetal cells.May 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Environ Chem. 2009 Jun ;91(3-4):735-749. Epub 2009 Jun 11. PMID: 24532866
Article Published Date : May 31, 2009
Study Type : Human In Vitro
Additional Links
Problem Substances : Aluminum, Lead, Mercury, Thimerosal
Adverse Pharmacological Actions : Neurotoxic
[+]

The pathogenic role of aluminium hydroxide is now recognized by the presence of chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma, linked to intramuscular injection of aluminium hydroxide-containing vaccines.Mar 14, 2012

Pubmed Data : J Trace Elem Med Biol. 2012 Mar 14. Epub 2012 Mar 14. PMID: 22425036
Article Published Date : Mar 14, 2012
Study Type : Human: Case Report, Review
Additional Links
Diseases : Chronic Fatigue Syndrome, Macrophagic myofasciitis , Pseudolymphoma
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic
[+]

A case of multiple sclerosis improvement following removal of heavy metal intoxication has been reported.Mar 22, 2012

Pubmed Data : Biometals. 2012 Mar 22. Epub 2012 Mar 22. PMID: 22438029
Article Published Date : Mar 22, 2012
Study Type : Human: Case Report
Additional Links
Diseases : Multiple Sclerosis
Problem Substances : Aluminum, Cadmium, Lead, Mercury
Adverse Pharmacological Actions : Neurotoxic
[+]

Central nervous system disease in patients with macrophagic myofasciitis.Apr 30, 2001

Pubmed Data : Brain. 2001 May ;124(Pt 5):974-83. PMID: 11335699
Article Published Date : Apr 30, 2001
Study Type : Human: Case Report
Additional Links
Diseases : Central Nervous System Diseases, Macrophagic myofasciitis
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Elevated urinary excretion of aluminium and iron in multiple sclerosis has been observed. Oct 01, 2006

Pubmed Data : Mult Scler. 2006 Oct ;12(5):533-40. PMID: 17086897
Article Published Date : Oct 01, 2006
Study Type : Human: Case Report
Additional Links
Substances : Silica
Diseases : Multiple Sclerosis
Problem Substances : Aluminum
[+]

Macrophagic myofasciitis associated with vaccine-derived aluminium.Jul 31, 2005

Pubmed Data : Med J Aust. 2005 Aug 1 ;183(3):145-6. PMID: 16053418
Article Published Date : Jul 31, 2005
Study Type : Human: Case Report
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum
[+]

Pediatric Wells syndrome (eosinophilic cellulitis) after vaccination.Aug 31, 2018

Pubmed Data : Pediatr Dermatol. 2018 Sep ;35(5):e262-e264. Epub 2018 Jul 12. PMID: 29998475
Article Published Date : Aug 31, 2018
Study Type : Human: Case Report
Additional Links
Diseases : Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
[+]

This case report described a man whose occupational exposure to aluminum suggests a role for aluminum in disease aetiology.Feb 10, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Med Case Rep. 2014 Feb 10 ;8:41. Epub 2014 Feb 10. PMID: 24513181
Article Published Date : Feb 10, 2014
Study Type : Human: Case Report
Additional Links
Diseases : Alzheimer's Disease
Problem Substances : Aluminum
[+]

"Aluminium content of drinking waters, fruit juices and soft drinks: contribution to dietary intake."Jun 26, 2002

Pubmed Data : Sci Total Environ. 2002 Jun 26 ;292(3):205-13. PMID: 12146520
Article Published Date : Jun 26, 2002
Study Type : Environmental
Additional Links
Problem Substances : Aluminium Cans
[+]

A histological study of toxic effects of aluminium sulfate on rat hippocampus.Jan 31, 2015

Pubmed Data : Biotech Histochem. 2015 Feb ;90(2):132-9. Epub 2014 Oct 14. PMID: 25314162
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

A white button mushroom extract acted as a potent dietary antioxidant and protects against Al-mediated neurotoxicity, by abrogating neuronal oxidative stress.Aug 31, 2014

Pubmed Data : Pak J Biol Sci. 2014 Sep ;17(9):1079-82. PMID: 26031030
Article Published Date : Aug 31, 2014
Study Type : Animal Study
Additional Links
Substances : White Button Mushroom
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Administration of resveratrol along with aluminum + fluoride showed significant reversal of oxidative stress and neuronal damage.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Interdiscip Toxicol. 2016 Jun ;9(2):78-82. Epub 2017 May 17. PMID: 28652849
Article Published Date : May 31, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Fluoride Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Sodium Fluoride
[+]

Alhydrogel injected at low dose in mouse muscle may selectively induce long-term Al cerebral accumulation and neurotoxic effects.Nov 27, 2016

Pubmed Data : Toxicology. 2016 Nov 28. Epub 2016 Nov 28. PMID: 27908630
Article Published Date : Nov 27, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Alum induces a Sjögren’s syndrome-like disorder in mice.Feb 28, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Clin Exp Rheumatol. 2014 Mar-Apr;32(2):251-5. Epub 2014 Apr 9. PMID: 24739520
Article Published Date : Feb 28, 2014
Study Type : Animal Study
Additional Links
Diseases : Sjogren's Syndrome, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminium accelerates the reduction of neural stem cells, cell proliferation, and neuroblast differentiation.Dec 31, 2013

Pubmed Data : Biol Trace Elem Res. 2014 Jan ;157(1):51-9. Epub 2013 Nov 22. PMID: 24265032
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , High Fat Diet
Problem Substances : Aluminum
[+]

Aluminium chelation by glutathione can provide an alleviatory remedy of neuropathic pain for cancer patients with oxaliplatin-induced neuropathic pain.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2017 ;9(3):926-939. Epub 2017 Mar 15. PMID: 28386322
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Glutathione
Diseases : Aluminum Toxicity , Chemotherapy-Induced Toxicity: Oxaliplatin, Neuropathic Pain
Pharmacological Actions : Chemoprotective Agents, Detoxifier
Problem Substances : Aluminum
[+]

Aluminium could induce imbalance of the normal intestinal flora in mice.Nov 30, 1998

Pubmed Data : Zhongguo Zhong Yao Za Zhi. 1998 Dec ;23(12):743-5, back cover. PMID: 12242827
Article Published Date : Nov 30, 1998
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Dysbiosis
Problem Substances : Aluminum
[+]

Aluminium may cause severe motor neuron damage in rat spinal cord resembling amyotrophic lateral sclerosis.Mar 31, 1999

Pubmed Data : Acta Histochem. 1999 Apr ;101(2):193-201. PMID: 10335362
Article Published Date : Mar 31, 1999
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Motor Neuron Disease
Additional Keywords : aluminum, aluminum toxicity, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Motor Neuron Disease
Problem Substances : Aluminum
[+]

Aluminium, fluoride and a combination of aluminium-fluoride treatments caused an increase in brain lipid peroxidation products and reactive oxygen species formation.Feb 28, 2015

Pubmed Data : Pathophysiology. 2015 Mar ;22(1):39-48. Epub 2014 Dec 13. PMID: 25577494
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Brain Inflammation , Fluoride Toxicity , Neurodegenerative Diseases, Oxidative Stress
Additional Keywords : Increased Risk, Synergistic Toxicity
Problem Substances : Aluminum, Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminium-adjuvanted vaccines transiently increase aluminium levels in murine brain tissue.Mar 31, 1992

Pubmed Data : Pharmacol Toxicol. 1992 Apr ;70(4):278-80. PMID: 1608913
Article Published Date : Mar 31, 1992
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminum adjuvants can impair social behaviour if applied in the early period of postnatal development.Nov 20, 2017

Pubmed Data : J Inorg Biochem. 2017 Nov 21. Epub 2017 Nov 21. PMID: 29221615
Article Published Date : Nov 20, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Social Behavior
Problem Substances : Aluminum Hydroxide
[+]

Aluminum adjuvants in vaccines are transported by the iron transporter, transferrin. This animal study demonstrates that cells in the brain have a high affinity for transferrin, independent of the metal being transported. Nov 01, 1990

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Proc Natl Acad Sci U S A. 1990 Nov ;87(22):9024-7. PMID: 2247478
Article Published Date : Nov 01, 1990
Study Type : Animal Study
Additional Links
Diseases : Neurodegenerative Diseases
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminum adjuvants linked to Gulf War illness induces motor neuron death in mice. Jan 01, 2007

Pubmed Data : Neuromolecular Med. 2007;9(1):83-100. PMID: 17114826
Article Published Date : Jan 01, 2007
Study Type : Animal Study
Additional Links
Diseases : Gulf War Syndrome, Vaccine-induced Toxicity
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum and copper in drinking water enhance inflammatory or oxidative events specifically in the brain.Jun 30, 2006

Pubmed Data : J Neuroimmunol. 2006 Jul ;176(1-2):16-23. Epub 2006 May 11. PMID: 16697052
Article Published Date : Jun 30, 2006
Study Type : Animal Study
Additional Links
Diseases : Brain: Oxidative Stress, Inflammation
Problem Substances : Aluminum, Public Drinking Water
[+]

Aluminum and ELF-MF may impact on learning memory and potentiate oxidative stress in mice.Dec 01, 2013

Pubmed Data : Biol Trace Elem Res. 2013 Dec ;156(1-3):243-52. Epub 2013 Oct 26. PMID: 24158621
Article Published Date : Dec 01, 2013
Study Type : Animal Study
Additional Links
Diseases : Memory Disorders, Oxidative Stress
Anti Therapeutic Actions : Electromagnetic Fields, Electromagnetic Radiation
Problem Substances : Aluminum
Adverse Pharmacological Actions : Oxidant
[+]

Aluminum appears to enhance the neurotoxic hazards caused by fluoride.Dec 31, 2008

Pubmed Data : Drug Chem Toxicol. 2009 ;32(3):215-21. PMID: 19538017
Article Published Date : Dec 31, 2008
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Lipid Peroxidation, Oxidative Stress
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Sodium Fluoride
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum based adjuvants causeed cell death and the subsequent release of host cell DNA, which acts as a potent endogenous immunostimulatory signal mediating alum adjuvant activity.Jul 31, 2011

Pubmed Data : Nat Med. 2011 Aug ;17(8):996-1002. Epub 2011 Jul 17. PMID: 21765404
Article Published Date : Jul 31, 2011
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Pharmacological Actions : Apoptotic
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide
[+]

Aluminum can induce neuroinflammation and could lead to learning and memory deficits.Apr 30, 2016

Pubmed Data : Chemosphere. 2016 May ;151:289-95. Epub 2016 Mar 15. PMID: 26946116
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Brain Inflammation , Cognitive Decline/Dysfunction
Additional Keywords : aluminum, aluminum toxicity, Brain Inflammation, Cognitive Decline/Dysfunction
Problem Substances : Aluminum
Adverse Pharmacological Actions : Inflammatory
[+]

Aluminum disrupts the prenatal development of the male and female gerbil prostate.Dec 31, 2018

Pubmed Data : Exp Mol Pathol. 2019 04 ;107:32-42. Epub 2019 Jan 17. PMID: 30659797
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Prenatal Chemical Exposures
Problem Substances : Aluminum
Adverse Pharmacological Actions : Endocrine Disruptor
[+]

Aluminum exposure at human dietary levels for 60 days reaches a threshold sufficient to promote memory impairment in rats.Dec 31, 2016

Pubmed Data : Neurotox Res. 2017 Jan ;31(1):20-30. Epub 2016 Jul 29. PMID: 27473855
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Memory Disorders
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum exposure at human dietary levels promotes vascular dysfunction and increases blood pressure in rats.Aug 17, 2017

Pubmed Data : Toxicology. 2017 Aug 18. Epub 2017 Aug 18. PMID: 28826906
Article Published Date : Aug 17, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
Adverse Pharmacological Actions : Cardiotoxic
[+]

Aluminum exposure may induced neuronal apoptosis in rats.Jun 30, 2015

Pubmed Data : Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2015 Jul ;33(7):535-8. PMID: 26653655
Article Published Date : Jun 30, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : aluminum, aluminum toxicity
Problem Substances : Aluminum
[+]

Aluminum hydroxide poisoning results in hematoxicity.Jan 05, 2000

Pubmed Data : Toxicol Lett. 2000 Jan 5;111(3):235-42. PMID: 10643868
Article Published Date : Jan 05, 2000
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Hematoxic
[+]

Aluminum is predominantly identified in macrophages after administration to normal mice.Mar 01, 1996

Pubmed Data : Pharmacol Toxicol. 1996 Mar ;78(3):123-8. PMID: 8882343
Article Published Date : Mar 01, 1996
Study Type : Animal Study
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide, Vaccine Adjuvants
[+]

Aluminum nanoparticles are more neurotoxic than micrometer aluminum.Jun 01, 2018

Pubmed Data : Biol Trace Elem Res. 2018 Jun ;183(2):261-269. Epub 2017 Aug 30. PMID: 28856594
Article Published Date : Jun 01, 2018
Study Type : Animal Study
Additional Links
Diseases : Lipid Peroxidation, Mitochondrial Dysfunction , Oxidative Stress
Additional Keywords : Vaccine Research
Problem Substances : Aluminum oxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Glutathione Down-Regulation, Oxidant
[+]

Aluminum nanoparticles, which are more neurotoxic than larger aluminum particles, are being investigated for use as vaccine adjuvants.Jan 10, 2014

Pubmed Data : J Control Release. 2014 Jan 10 ;173:148-57. Epub 2013 Nov 1. PMID: 24188959
Article Published Date : Jan 10, 2014
Study Type : Animal Study
Additional Links
Additional Keywords : Vaccine Research
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum oxide nanomaterials are genotoxic in rat peripheral blood cells. May 01, 2009

Pubmed Data : Mutagenesis. 2009 May;24(3):245-51. Epub 2009 Feb 23. PMID: 19237533
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum oxide
[+]

Aluminum oxide nanomaterials have the potential to cause genetic damage.May 31, 2009

Pubmed Data : Mutat Res. 2009 May 31;676(1-2):41-7. Epub 2009 Mar 31. PMID: 19486863
Article Published Date : May 31, 2009
Study Type : Animal Study
Additional Links
Diseases : DNA damage
Problem Substances : Aluminum oxide
[+]

Aluminum trichloride may induce hypertension by disturbing the function of erythrocyte membrane.Sep 09, 2015

Pubmed Data : Biol Trace Elem Res. 2015 Sep 10. Epub 2015 Sep 10. PMID: 26354416
Article Published Date : Sep 09, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
Adverse Pharmacological Actions : Hypertensive
[+]

Aluminum--based adjuvants induce persistent, sterile, subcutaneous granulomas with macrophage-driven translocation of aluminum to regional lymph nodes in sheep.Jan 01, 2019

Pubmed Data : Vet Pathol. 2019 05 ;56(3):418-428. Epub 2018 Oct 31. PMID: 30381018
Article Published Date : Jan 01, 2019
Study Type : Animal Study
Additional Links
Diseases : Granuloma, Vaccine-induced Toxicity
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

B. monniera whole-plant extracts can be considered as a possible remedy to counteract aluminum-associated neurological disorders.Oct 30, 2014

Pubmed Data : Chin J Physiol. 2014 Oct 31 ;57(5):279-85. PMID: 25241988
Article Published Date : Oct 30, 2014
Study Type : Animal Study
Additional Links
Substances : Bacopa
Diseases : Aluminum Toxicity , Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Bacopa monniera silver nanoparticles are able to eradicate the oxidative stress and prevent the tissue damage in aluminum exposed mice.Jan 31, 2015

Pubmed Data : J Nanosci Nanotechnol. 2015 Feb ;15(2):1101-9. PMID: 26353618
Article Published Date : Jan 31, 2015
Study Type : Animal Study
Additional Links
Substances : Bacopa, Silver (nanoparticles)
Diseases : Aluminum Toxicity , Oxidative Stress
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Banana pectin extract can effectively reduce aluminum toxicity in mice.Jun 30, 2018

Pubmed Data : Drug Chem Toxicol. 2018 Jul ;41(3):294-301. Epub 2018 Mar 26. PMID: 29578368
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Banana, Pectin
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Beverages in aluminium cans have been shown to contain aluminium levels from .1 to 74 parts per million (ppm), depending on the product and storage time.Sep 01, 1997

Pubmed Data : Toxicol Ind Health. 1997 Sep-Oct;13(5):649-54. PMID: 9284535
Article Published Date : Sep 01, 1997
Study Type : Animal Study
Additional Links
Problem Substances : Aluminium Cans, Sugary soda
[+]

Both aluminum hydroxide adjuvant and formaldehyde raise antibody levels when used in vaccines.Apr 12, 2007

Pubmed Data : Vaccine. 2007 Apr 12;25(15):2771-7. Epub 2007 Jan 2. PMID: 17240008
Article Published Date : Apr 12, 2007
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum Hydroxide, Formaldehyde
[+]

Bumblebee pupae contain high levels of aluminium.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(6):e0127665. Epub 2015 Jun 4. PMID: 26042788
Article Published Date : Dec 31, 2014
Study Type : Insect Study
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Bee Colony Collapse
Problem Substances : Aluminum
[+]

Calcium carbonate is associated with the progression of kidney calcification in uremic rats. Sep 01, 2002

Pubmed Data : J Am Soc Nephrol. 2002 Sep;13(9):2299-308. PMID: 12191974
Article Published Date : Sep 01, 2002
Study Type : Animal Study
Additional Links
Diseases : Uremia
Problem Substances : Antacids: Aluminium-Containing, Calcium Carbonate
[+]

Cheese in a serving of frozen pizzas had up to 14 mg of Al, from basic sodium aluminium phosphate.Mar 01, 2005

Pubmed Data : Food Addit Contam. 2005 Mar ;22(3):234-44. PMID: 16019791
Article Published Date : Mar 01, 2005
Study Type : Environmental
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Sodium aluminium phosphate.
[+]

Chlorogenic acid supplementation may be favourable to avoid aluminium induced hematotoxicity and hepatotoxicity for humans.Jul 31, 2017

Pubmed Data : Chem Biol Interact. 2017 Aug 1 ;273:125-132. Epub 2017 Jun 13. PMID: 28623112
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, Hepatoprotective
Problem Substances : Aluminum
[+]

Co-exposure to aluminum and acrylamide exhibited synergism and more pronounced toxic effects compared with their individual effects.Apr 08, 2015

Pubmed Data : Environ Toxicol. 2015 Apr 9. Epub 2015 Apr 9. PMID: 25858877
Article Published Date : Apr 08, 2015
Study Type : Animal Study
Additional Links
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity , Kidney Damage: Chemically-Induced
Additional Keywords : Synergistic Toxicity
Problem Substances : Acrylamide , Aluminum
Adverse Pharmacological Actions : Genotoxic, Inflammatory
[+]

Curcumin could ameliorate aluminium induced testicular damage. Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Fertil Steril. 2017 Oct ;11(3):166-175. Epub 2017 Aug 27. PMID: 28868838
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Aluminum Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants, Cytoprotective
Problem Substances : Aluminum
[+]

Curcumin may act as a neuroprotectant against aluminum-induced neurodegenerative and behavioural disorders.Dec 31, 2017

Pubmed Data : J Environ Pathol Toxicol Oncol. 2018 ;37(2):163-172. PMID: 30055551
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Curcumin supplementation to aluminum treated rats was able to normalize significantly the activities of all the three mitochondrial complexes.Oct 31, 2011

Pubmed Data : Neurotox Res. 2011 Nov ;20(4):351-61. Epub 2011 Jun 9. PMID: 21656326
Article Published Date : Oct 31, 2011
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Deleterious effects of aluminum on intestinal inflammation and mucosal repair strongly suggest that aluminum might be an environmental IBD risk factor.Apr 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mucosal Immunol. 2014 May ;7(3):589-601. Epub 2013 Oct 16. PMID: 24129165
Article Published Date : Apr 30, 2014
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Colitis, Inflammatory Bowel Diseases, Wound Healing
Additional Keywords : Risk Factors
Problem Substances : Aluminum
[+]

Emblica officinalis could be a promising therapeutic aid against aluminium-induced neurotoxicity.Jan 31, 2019

Pubmed Data : Neurotox Res. 2019 Feb ;35(2):318-330. Epub 2018 Sep 21. PMID: 30242626
Article Published Date : Jan 31, 2019
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Excessive fluoride and aluminium intake induces the progression of cell death which inhibit AChE activities and trigger the release of lysosomal and cell cycle proteins.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pathophysiology. 2015 Jun ;22(2):105-15. Epub 2015 Apr 2. PMID: 25863844
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Neurodegenerative Diseases
Additional Keywords : Increased Risk
Problem Substances : Aluminum, Fluoride, Sodium Fluoride
Adverse Pharmacological Actions : Neurotoxic
[+]

Extra virgin olive oil can decrease the frequency of cardiac complications and genotoxicity induced by co-exposure to aluminum and acrylamide.Sep 01, 2015

Pubmed Data : Food Funct. 2015 Sep 2 ;6(9):3098-108. PMID: 26215160
Article Published Date : Sep 01, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective, Genoprotective
Problem Substances : Acrylamide , Aluminum
Adverse Pharmacological Actions : Genotoxic
[+]

Extra virgin olive oil may have a beneficial role in decreasing the liver damage induced by both aluminum and acrylamide.Mar 31, 2015

Pubmed Data : Food Funct. 2015 Apr ;6(4):1126-35. PMID: 25690328
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Olive Oil
Diseases : Acrylamide-induced toxicity, Aluminum Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Hepatoprotective
Problem Substances : Acrylamide , Aluminum
[+]

Folic acid improves developmental toxicity induced by aluminum sulphates.Feb 28, 2017

Pubmed Data : Environ Toxicol Pharmacol. 2017 Mar ;50:32-36. Epub 2017 Jan 18. PMID: 28119228
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Folic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Aluminum
[+]

Garden cress has a protective effect on aluminium induced impairment of the liver and kidneys. Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2019 ;2019:4516730. Epub 2019 Jul 18. PMID: 31396529
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Garden Cress (Lepidium sativum)
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Aluminum
[+]

Ginkgo biloba attenuates aluminum lactate-induced neurotoxicity in reproductive senescent female rats.Jul 17, 2019

Pubmed Data : Environ Sci Pollut Res Int. 2019 Jul 18. Epub 2019 Jul 18. PMID: 31321719
Article Published Date : Jul 17, 2019
Study Type : Animal Study
Additional Links
Substances : Ginkgo biloba
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Hepatitis B vaccine induces cell death in liver cells and mouse liver. Jan 17, 2012

Pubmed Data : Apoptosis. 2012 Jan 17. Epub 2012 Jan 17. PMID: 22249285
Article Published Date : Jan 17, 2012
Study Type : Animal Study
Additional Links
Diseases : Liver Damage, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All, Vaccination: Hepatitis B
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Hepatotoxic
[+]

Hesperidin could be a potential therapeutic agent in the treatment of oxidative stress associated neurodegenerative diseases.Feb 14, 2016

Pubmed Data : Nutr Neurosci. 2016 Feb 15. Epub 2016 Feb 15. PMID: 26878879
Article Published Date : Feb 14, 2016
Study Type : Animal Study
Additional Links
Substances : Hesperidin
Diseases : Aluminum Toxicity , Alzheimer's Disease, Brain: Oxidative Stress, Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum
[+]

High selenium yeast mitigates aluminum-induced cerebral inflammation.Jul 15, 2018

Pubmed Data : Biometals. 2018 Jul 16. Epub 2018 Jul 16. PMID: 30014352
Article Published Date : Jul 15, 2018
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Hyperforin attenuates aluminum-induced Aβ production and Tau phosphorylation.Sep 25, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep 26 ;96:1-6. Epub 2017 Sep 26. PMID: 28961505
Article Published Date : Sep 25, 2017
Study Type : Animal Study
Additional Links
Substances : Hyperforin
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model.Oct 31, 2014

Pubmed Data : J Autoimmun. 2014 Nov ;54:21-32. Epub 2014 Jul 16. PMID: 25042822
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Anxiety Disorders, Systemic Lupus Erythematosus, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: Hepatitis B
Problem Substances : Aluminum Hydroxide
[+]

L. plantarum CCFM639 could alleviate aluminum induced hepatic and renal injuries.Sep 13, 2016

Pubmed Data : Biol Trace Elem Res. 2016 Sep 14. Epub 2016 Sep 14. PMID: 27627960
Article Published Date : Sep 13, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Aluminum Toxicity
Pharmacological Actions : Hepatoprotective, Renoprotective
Problem Substances : Aluminum
[+]

L. plantarum CCFM639 has a potential as dietary supplement ingredient that provides protection against aluminum induced injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(4):e0175398. Epub 2017 Apr 7. PMID: 28388664
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Problem Substances : Aluminum
[+]

L. plantarum CCFM639 has potential as a therapeutic dietary strategy against acute aluminium toxicity. Jan 31, 2016

Pubmed Data : Appl Microbiol Biotechnol. 2016 Feb ;100(4):1891-900. Epub 2015 Nov 26. PMID: 26610803
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Aluminum Toxicity , Brain: Oxidative Stress, Oxidative Stress
Pharmacological Actions : Antioxidants, Hepatoprotective, Renoprotective
Problem Substances : Aluminum
[+]

L. plantarum CCFM639 has the potential to be a dietary supplement ingredient that provides protection against Al-induced gut injury.Dec 01, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Dec 2 ;8(12). Epub 2016 Dec 2. PMID: 27918411
Article Published Date : Dec 01, 2016
Study Type : Animal Study
Additional Links
Substances : Lactobacillus plantarum
Diseases : Aluminum Toxicity
Pharmacological Actions : Gastroprotective
Problem Substances : Aluminum
[+]

Lavender oil and especially linalool could be a potential agent for improving cognitive impairment in Alzheimer's disease.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2017 ;2017:7426538. Epub 2017 Apr 26. PMID: 28529531
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Lavender, Lavender: Essential Oil
Diseases : Alzheimer's Disease, Cognitive Decline/Dysfunction
Pharmacological Actions : Antioxidants, Heme oxygenase-1 up-regulation, Neuroprotective Agents, Nrf2 activation
Additional Keywords : Alzheimer's disease, Antioxidants, Cognitive Decline/Dysfunction, lavender, Lavender: Essential Oil
Problem Substances : Aluminum
[+]

Lead and aluminum concentrations in water may be dangerous to the health of the population.Jun 01, 1979

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 1979 Jun ;30:47-51. PMID: 446457
Article Published Date : Jun 01, 1979
Study Type : Animal Study
Additional Links
Problem Substances : Aluminum, Lead
[+]

Low concentrations of aluminium in testes are sufficient to impair spermatogenesis and sperm quality.Sep 30, 2017

Pubmed Data : Reprod Toxicol. 2017 Oct ;73:128-141. Epub 2017 Aug 18. PMID: 28823769
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Infertility: Male
Additional Keywords : aluminum, aluminum toxicity, Infertility: Male
Problem Substances : Aluminum
[+]

Low cytochrome C oxidase is associated with Alzheimer's disease. This in vivo animal study indicates that certain heavy metals may induce oxidative stress and downregulate cytochrome C oxidase activity.Mar 01, 2011

Pubmed Data : J Mol Neurosci. 2011 Mar ;43(3):284-9. Epub 2010 Aug 20. PMID: 20725867
Article Published Date : Mar 01, 2011
Study Type : Animal Study
Additional Links
Diseases : Mitochondrial Dysfunction
Additional Keywords : brain health
Problem Substances : Aluminum, Heavy Metals
Adverse Pharmacological Actions : Neurotoxic, Oxidant
[+]

Mechanisms underlying aluminium neurotoxicity related to 14-3-3ζ protein.Jan 26, 2018

Pubmed Data : Toxicol Sci. 2018 Jan 27. Epub 2018 Jan 27. PMID: 29385627
Article Published Date : Jan 26, 2018
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Melatonin could protect against aluminum-induced toxicity in rats.Jul 15, 2015

Pubmed Data : Gen Physiol Biophys. 2015 Jul 16. Epub 2015 Jul 16. PMID: 26374992
Article Published Date : Jul 15, 2015
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hypolipidemic
Problem Substances : Aluminum
[+]

Melatonin reduces oxidative stress and increases gene expression in the cerebral cortex and cerebellum of aluminum-exposed rats.Aug 31, 2005

Pubmed Data : J Pineal Res. 2005 Sep ;39(2):129-36. PMID: 16098089
Article Published Date : Aug 31, 2005
Study Type : Animal Study
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : Gene Expression Regulation
Problem Substances : Aluminum
[+]

Memory enhancement of acteoside in a senescent mice model.Jul 31, 2015

Pubmed Data : Phytother Res. 2015 Aug ;29(8):1131-6. Epub 2015 Apr 21. PMID: 25900014
Article Published Date : Jul 31, 2015
Study Type : Animal Study
Additional Links
Substances : Verbascoside
Diseases : Aging, Aluminum Toxicity , Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Moringa oleifera extract could be used as adjuvant therapy against aluminium phosphide-induced cardiotoxicity.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicol Rep. 2018 ;5:209-212. Epub 2018 Jan 28. PMID: 29387566
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Cardioprotective
Problem Substances : Aluminum
[+]

Moringa oleifera protects against Aluminium induced neurotoxicity of the temporal cortex of rats.Apr 10, 2017

Pubmed Data : Metab Brain Dis. 2017 Apr 11. Epub 2017 Apr 11. PMID: 28397152
Article Published Date : Apr 10, 2017
Study Type : Animal Study
Additional Links
Substances : Moringa oleifera
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Mung bean polyphenol extract has a cardiac protective effect against aluminum induced biotoxicity.Feb 21, 2017

Pubmed Data : Food Funct. 2017 Feb 22 ;8(2):851-859. PMID: 28128384
Article Published Date : Feb 21, 2017
Study Type : Animal Study
Additional Links
Substances : Mung Bean
Diseases : Aluminum Toxicity , Oxidative Stress
Pharmacological Actions : Cardioprotective, Chelating Agents, Malondialdehyde Down-regulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
Problem Substances : Aluminum
[+]

Nano-alumina particles induced Alzheimer disease neuropathology by enhancing the amyloidogenic pathway of amyloid beta production and aggregation.Sep 20, 2015

Pubmed Data : Nanoscale. 2015 Sep 21 ;7(37):15225-37. PMID: 26315713
Article Published Date : Sep 20, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Neurodegenerative Diseases
Additional Keywords : Risk Factors
Problem Substances : Aluminum oxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Nanoalumina stimulates mitochondrial dysfunction, leading to overactive autophagic degradation and results in apoptosis. This was confirmed by upregulation of apoptotic genes in the brains of nanoalumina-treated mice.Feb 01, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nanomedicine. 2013 Feb ;9(2):212-21. Epub 2012 Jun 9. PMID: 22687898
Article Published Date : Feb 01, 2013
Study Type : Animal Study
Additional Links
Diseases : Mitochondrial Dysfunction , Stroke, Stroke: Ischemic
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum oxide, Nanoparticles, Vaccine Adjuvants
Adverse Pharmacological Actions : Apoptotic, Blood Brain Barrier Injury, Inflammatory, Neurotoxic, Oxidant
[+]

Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer's disease rat model.Aug 27, 2019

Pubmed Data : J Histotechnol. 2019 Aug 28:1-10. Epub 2019 Aug 28. PMID: 31460853
Article Published Date : Aug 27, 2019
Study Type : Animal Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Omega3 FAs supplementation can lighten the toxic effects of aluminum through their antioxidant and free radical-scavenging effects.Apr 07, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Apr 8. Epub 2016 Apr 8. PMID: 27055897
Article Published Date : Apr 07, 2016
Study Type : Animal Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Cytoprotective
Problem Substances : Aluminum
[+]

Prolonged aluminium sulphate intake accelerates features of senescence in the adult mice liver.Mar 31, 2008

Pubmed Data : Exp Gerontol. 2008 Apr ;43(4):330-8. Epub 2008 Feb 2. PMID: 18337038
Article Published Date : Mar 31, 2008
Study Type : Animal Study
Additional Links
Diseases : Aging, Aluminum Toxicity
Problem Substances : Aluminum
[+]

Protective effects of alpha-ketoglutarate against aluminum toxicity in Drosophila melanogaster.Nov 29, 2018

Pubmed Data : Comp Biochem Physiol C Toxicol Pharmacol. 2018 Nov 30 ;217:41-53. Epub 2018 Nov 30. PMID: 30508642
Article Published Date : Nov 29, 2018
Study Type : Insect Study
Additional Links
Substances : Alpha Ketoglutarate
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum
[+]

Rats fed with canned soft drinks had higher concentrations of Aluminum in blood, liver and bone than rats fed with glass bottled soft drinks. Jan 01, 1994

Pubmed Data : Biometals. 1994 Jan ;7(1):57-60. PMID: 8118174
Article Published Date : Jan 01, 1994
Study Type : Animal Study
Additional Links
Diseases : Osteoporosis
Problem Substances : Aluminium Cans, Sugary soda
[+]

Repetitive administration of aluminium to neonatal mice in amounts comparable to those to children receive via routine vaccinations result in neurodisruptive effects.Oct 31, 2013

Pubmed Data : J Inorg Biochem. 2013 Nov ;128:237-44. Epub 2013 Jul 19. PMID: 23932735
Article Published Date : Oct 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Autism Spectrum Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

Resveratrol is effective in preventing aluminium induced toxicity by reducing MDA production in cerebral tissue.Dec 31, 2016

Pubmed Data : Bratisl Lek Listy. 2017 ;118(5):269-272. PMID: 28516788
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Resveratrol
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Malondialdehyde Down-regulation, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Role of Spirulina in mitigating hemato-toxicity in Swiss albino mice exposed to aluminum and aluminum fluoride.Nov 30, 2016

Pubmed Data : Environ Sci Pollut Res Int. 2016 Dec ;23(24):25280-25287. Epub 2016 Sep 29. PMID: 27687764
Article Published Date : Nov 30, 2016
Study Type : Animal Study
Additional Links
Substances : Spirulina
Diseases : Aluminum Toxicity , Fluoride Toxicity
Pharmacological Actions : Cytoprotective
Problem Substances : Aluminum, Sodium Fluoride
[+]

Selenium-rich yeast mitigates aluminum-mediated testicular toxicity.Jul 20, 2019

Pubmed Data : Biol Trace Elem Res. 2019 Jul 21. Epub 2019 Jul 21. PMID: 31327124
Article Published Date : Jul 20, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium
Diseases : Aluminum Toxicity , Testicular Injury: Chemical/Metal Induced
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum
[+]

Selenium-rich yeast protects against aluminum-induced peroxidation of lipide and inflammation in mice liver.Oct 03, 2018

Pubmed Data : Biometals. 2018 Oct 4. Epub 2018 Oct 4. PMID: 30288658
Article Published Date : Oct 03, 2018
Study Type : Animal Study
Additional Links
Substances : Selenium, Yeast
Diseases : Aluminum Toxicity , Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Heme oxygenase-1 up-regulation, Hepatoprotective, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum
[+]

Selenium-rich-yeast exerts a cardio-protective effect against aluminum-induced toxicity.Jun 21, 2019

Pubmed Data : Biol Trace Elem Res. 2019 Jun 22. Epub 2019 Jun 22. PMID: 31230209
Article Published Date : Jun 21, 2019
Study Type : Animal Study
Additional Links
Substances : Selenium, Yeast
Diseases : Aluminum Toxicity , Cardiovascular Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective
Problem Substances : Aluminum
[+]

Sesamol, a lipid lowering agent, ameliorates aluminium chloride induced behavioral and biochemical alterations in rats.Mar 31, 2015

Pubmed Data : Pharmacogn Mag. 2015 Apr-Jun;11(42):327-36. PMID: 25829772
Article Published Date : Mar 31, 2015
Study Type : Animal Study
Additional Links
Substances : Sesamol
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

The aluminum (AI) level in milk kept in Al containers and dairy products packed in Al foil is beyond the permissible limits, suggesting health hazard. Apr 01, 2011

Pubmed Data : J Food Sci. 2011 Apr ;76(3):T73-6. Epub 2011 Mar 16. PMID: 21535864
Article Published Date : Apr 01, 2011
Study Type : Environmental
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
[+]

The effects of low dose aluminum on hemorheological and hematological parameters in rats.Dec 31, 2006

Pubmed Data : Arch Toxicol. 2007 Jan ;81(1):11-7. Epub 2006 May 24. PMID: 16721596
Article Published Date : Dec 31, 2006
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
[+]

There was structural changes of Purkinje cells and iron and aluminium accumulations in stratum granulosum of rabbit's cerebellum after exposure to RF EMF.Dec 31, 2016

Pubmed Data : Bratisl Lek Listy. 2017 ;118(10):575-579. PMID: 29198122
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Electromagnetic Fields
Problem Substances : Aluminum
[+]

These findings demonstrate that environmental concentrations of aluminium induce oxidative and immunotoxic effects in fish.Oct 31, 2014

Pubmed Data : Environ Sci Pollut Res Int. 2014 Nov ;21(22):13103-17. Epub 2014 Jul 6. PMID: 24996940
Article Published Date : Oct 31, 2014
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Problem Substances : Aluminum
[+]

These findings indicate that oral exposure to aluminum at human dietary level reproduces clinical and molecular features of Irritable bowel syndrome.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Mol Gastroenterol Hepatol. 2019 ;7(1):185-196. Epub 2018 Sep 20. PMID: 30534582
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Gastrointestinal Inflammation, Irritable Bowel Syndrome
Additional Keywords : Increased Risk
Problem Substances : Aluminum
[+]

These findings showed that aluminum exposure caused spatial memory damage.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol Sci. 2013 ;38(2):255-68. PMID: 23535404
Article Published Date : Dec 31, 2012
Study Type : Animal Study, In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Memory Disorders
Additional Keywords : aluminum, aluminum toxicity, Memory Disorders
Problem Substances : Aluminum
[+]

These findings suggest that aluminium may be considered toxic for the peripheral nervous system.Aug 24, 2017

Pubmed Data : J Inorg Biochem. 2017 Aug 25. Epub 2017 Aug 25. PMID: 28865725
Article Published Date : Aug 24, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Peripheral Neuropathies
Additional Keywords : aluminum, aluminum toxicity, Peripheral Neuropathies, Risk Factors
Problem Substances : Aluminum oxide
[+]

These results indicate that SIRT1 and TORC1 might play an important mediating role in aluminium -induced long-term memory impairment.Sep 30, 2017

Pubmed Data : Basic Clin Pharmacol Toxicol. 2017 Oct ;121(4):342-352. Epub 2017 Jun 19. PMID: 28429887
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity , Memory Disorders, Neurodegenerative Diseases
Additional Keywords : aluminum, aluminum toxicity, Memory Disorders, Neurodegenerative diseases
Problem Substances : Aluminum
[+]

This in vivo study adds to the evidence that aluminum adjuvants are linked to autoimmunity.Jan 01, 2018

Pubmed Data : Front Immunol. 2018 ;9:2406. Epub 2018 Oct 23. PMID: 30405610
Article Published Date : Jan 01, 2018
Study Type : Animal Study
Additional Links
Diseases : Autoimmune Syndrome Induced by Adjuvants (ASIA), DNA damage, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

This study outlines aluminum's dose-dependent cardiotoxic effects.Nov 01, 2018

Pubmed Data : Environ Pollut. 2018 Nov ;242(Pt A):814-826. Epub 2018 Jul 17. PMID: 30032078
Article Published Date : Nov 01, 2018
Study Type : Animal Study
Additional Links
Additional Keywords : Vaccine Research
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Cardiotoxic, Inflammatory, Oxidant
[+]

This study supports previous findings that indicate aluminum is a persistent bioaccumulator in vivo via aluminum adjuvant intramuscular injection.Nov 01, 2015

Pubmed Data : J Inorg Biochem. 2015 Nov ;152:199-205. Epub 2015 Jul 22. PMID: 26384437
Article Published Date : Nov 01, 2015
Study Type : Animal Study
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Bioaccumulator, Neurotoxic
[+]

Treatment with quercetin may represent a therapeutic strategy to attenuate the neuronal death against aluminum-induced neurodegeneration.Mar 01, 2016

Pubmed Data : Neuroscience. 2016 Mar 2. Epub 2016 Mar 2. PMID: 26944603
Article Published Date : Mar 01, 2016
Study Type : Animal Study
Additional Links
Substances : Quercetin
Diseases : Aluminum Toxicity , Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Yerba mate has potential antioxidant effects on aluminium toxicity.Nov 06, 2017

Pubmed Data : J Inorg Biochem. 2017 Nov 7. Epub 2017 Nov 7. PMID: 29150325
Article Published Date : Nov 06, 2017
Study Type : Animal Study
Additional Links
Substances : Yerba Mate
Diseases : Aluminum Toxicity , Alzheimer's Disease
Pharmacological Actions : Antioxidants, Neuroprotective Agents
Additional Keywords : aluminum, aluminum toxicity, Alzheimer's disease, Antioxidants, Neuroprotective Agents, Yerba Mate
Problem Substances : Aluminum
[+]

"Hypothesis: is Alzheimer's disease a metal-induced immune disorder?"Feb 28, 1995

Pubmed Data : Neurodegeneration. 1995 Mar ;4(1):107-11. PMID: 7600179
Article Published Date : Feb 28, 1995
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

"Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations."Jan 01, 2012

Pubmed Data : Lupus. 2012 ;21(2):223-30. PMID: 22235057
Article Published Date : Jan 01, 2012
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide, Vaccine Adjuvants
[+]

A review of metal toxicity linked to Alzheimer's disease and neuroinflammation.Jan 17, 2019

Pubmed Data : J Mol Biol. 2019 Jan 18. Epub 2019 Jan 18. PMID: 30664867
Article Published Date : Jan 17, 2019
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation
Problem Substances : Aluminum, Cadmium, Lead
[+]

A review of the multifaceted effects of aluminium in neurodegenerative diseases.Sep 30, 2016

Pubmed Data : Biomed Pharmacother. 2016 Oct ;83:746-754. Epub 2016 Jul 29. PMID: 27479193
Article Published Date : Sep 30, 2016
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Neurodegenerative Diseases
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

A review of the role of melatonin in aluminum-related neurodegenerative disorders.May 06, 2018

Pubmed Data : Biol Trace Elem Res. 2018 May 7. Epub 2018 May 7. PMID: 29732485
Article Published Date : May 06, 2018
Study Type : Review
Additional Links
Substances : Melatonin
Diseases : Aluminum Toxicity , Neurodegenerative Diseases
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

A significant correlation exists between the number of pediatric aluminum-adjuvanted vaccines administered and the rate of autism spectrum disorders.Jun 30, 2013

Pubmed Data : Immunol Res. 2013 Jul ;56(2-3):304-16. PMID: 23609067
Article Published Date : Jun 30, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autism Spectrum Disorders
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

A wide range of metals have been identified to have estrogenic properties.May 01, 2006

Pubmed Data : J Appl Toxicol. 2006 May-Jun;26(3):191-7. PMID: 16489580
Article Published Date : May 01, 2006
Study Type : Review
Additional Links
Diseases : Cancers: Estrogen Responsive, Estrogen Dominance, Heavy Metal Toxicity
Additional Keywords : Metalloestrogens
Problem Substances : Aluminum, Antimony, Arsenite, Barium, Cadmium, Chromium Chloride, Cobalt, Industrial Copper (inorganic), Lead, Mercury, Selenite, Tin, Vanadate
Adverse Pharmacological Actions : Estrogenic
[+]

According to Sir Austin Bradford Hill's causality criteria, chronic aluminum intake causes Alzheimer's disease.Jan 01, 2014

Pubmed Data : J Alzheimers Dis. 2014 ;40(4):765-838. PMID: 24577474
Article Published Date : Jan 01, 2014
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Adjuvants and vaccine induced autoimmunity.Dec 31, 2016

Pubmed Data : Immunol Res. 2017 02 ;65(1):55-65. PMID: 27417999
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Vaccine-induced Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Adjuvants for human vaccines-current status, problems and future prospects.Sep 30, 1995

Pubmed Data : Vaccine. 1995 Oct ;13(14):1263-76. PMID: 8585280
Article Published Date : Sep 30, 1995
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Adverse reactions after injection of adsorbed DTP vaccine are not due only to pertussis organisms or pertussis components in the vaccine.Sep 30, 1991

Pubmed Data : Vaccine. 1991 Oct ;9(10):699-702. PMID: 1759487
Article Published Date : Sep 30, 1991
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Vaccine-induced Toxicity
Additional Keywords : Vaccine Contamination
Anti Therapeutic Actions : Vaccination: Diphtheria-Pertussis-Tetanus, Vaccination: DPT
Problem Substances : Aluminum
[+]

All of the 30 infant formulas tested were contaminated with aluminium.Oct 07, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Pediatr. 2013 Oct 8 ;13:162. Epub 2013 Oct 8. PMID: 24103160
Article Published Date : Oct 07, 2013
Study Type : In Vitro Study
Additional Links
Problem Substances : Aluminum, Infant Formula
[+]

Alpha synuclein protein is involved in Aluminum-induced cell death and oxidative stress in PC12 cells.Jan 26, 2016

Pubmed Data : Brain Res. 2016 Jan 27. Epub 2016 Jan 27. PMID: 26826584
Article Published Date : Jan 26, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Parkinson's Disease
Problem Substances : Aluminum
[+]

Aluminic macrophagic myofasciitis is associated with fatigue and cognitive dysfunction. Animal studies indicate the ability of adjuvant particles to migrate slowly and bioaccumulate in other organs, stronglt implicating a need for longer safety studies.Jun 01, 2016

Pubmed Data : Morphologie. 2016 Jun ;100(329):85-94. Epub 2016 Apr 6. PMID: 26948677
Article Published Date : Jun 01, 2016
Study Type : Review
Additional Links
Diseases : Cognitive Decline/Dysfunction, Fatigue
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Bioaccumulator, Neurotoxic
[+]

Aluminium beverage cans are susceptible to leaching aluminium, especially in cola products that contan orthophosphoric acid.Apr 01, 1996

Pubmed Data : Z Lebensm Unters Forsch. 1996 Apr;202(4):308-12. PMID: 8638433
Article Published Date : Apr 01, 1996
Study Type : In Vitro Study
Additional Links
Problem Substances : Aluminium Cans, Sugary soda
[+]

Aluminium beverage cans contribute significant amounts of aluminium, particularly in beverages with decreasing ph such as soft drinksMay 04, 1992

Pubmed Data : Med J Aust. 1992 May 4;156(9):604-5. PMID: 1625612
Article Published Date : May 04, 1992
Study Type : In Vitro Study
Additional Links
Diseases : Alzheimer's Disease
Problem Substances : Aluminium Cans, Sugary soda
[+]

Aluminium cans contiribute to aluminium intake, especially when the contents are acidic in ph. Apr 01, 1994

Pubmed Data : Z Lebensm Unters Forsch. 1994 Apr;198(4):313-6. PMID: 8197828
Article Published Date : Apr 01, 1994
Study Type : In Vitro Study
Additional Links
Problem Substances : Aluminium Cans, Sugary soda
[+]

Aluminium has been demonstrated to impact the CNS at every level, including by changing gene expression.Dec 31, 2013

Pubmed Data : Immunotherapy. 2014 ;6(10):1055-71. PMID: 25428645
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Neurodegenerative Diseases
Additional Keywords : aluminum, aluminum toxicity, Autoimmune Diseases, Gene Expression, Neurodegenerative diseases, Vaccine Adjuvants
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Aluminium has been shown to cause adverse alterations to the breast microenvironment.May 31, 2016

Pubmed Data : Morphologie. 2016 Jun ;100(329):65-74. Epub 2016 Mar 17. PMID: 26997127
Article Published Date : May 31, 2016
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer
Problem Substances : Aluminum
[+]

Aluminium hydroxide and calcium phosphate adjuvants have a immunotoxic and haemolytic effects.Jan 01, 1993

Pubmed Data : Vaccine. 1993;11(9):914-8. PMID: 8212836
Article Published Date : Jan 01, 1993
Study Type : In Vitro Study
Additional Links
Additional Keywords : Adjuvant Toxicity
Problem Substances : Aluminum Hydroxide, Calcium Phosphate
Adverse Pharmacological Actions : Hemolytic, Immunosuppressive, Immunotoxic
[+]

Aluminium in foodstuff and the influence of aluminium foil used for food preparation or short time storage.May 31, 2018

Pubmed Data : Food Addit Contam Part B Surveill. 2018 Jun ;11(2):153-159. Epub 2018 Mar 16. PMID: 29486656
Article Published Date : May 31, 2018
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
[+]

Aluminium may play an active role in the pathogenesis of critical neuropathologic lesion in Alzheimer's disease and other related disorders.Jan 01, 2006

Pubmed Data : J Alzheimers Dis. 2006 ;9(3 Suppl):291-300. PMID: 17004365
Article Published Date : Jan 01, 2006
Study Type : Review
Additional Links
Diseases : Neurodegenerative Diseases
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum adjuvants may have potentially distinct roles in vaccine-related adverse events.Jan 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Allergy Asthma Clin Immunol. 2018 ;14:80. Epub 2018 Nov 7. PMID: 30455719
Article Published Date : Jan 01, 2018
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Cytotoxic
[+]

Aluminum affects neural phenotype determination of embryonic neural progenitor cells.Jul 29, 2019

Pubmed Data : Arch Toxicol. 2019 Jul 30. Epub 2019 Jul 30. PMID: 31363819
Article Published Date : Jul 29, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Prenatal Chemical Exposures
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum and benzo[a]pyrene co-operate to induce neuronal apoptosis in vitro.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol Sci. 2015 Jun ;40(3):365-73. PMID: 25971159
Article Published Date : May 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Benzo[a]pyrene-induced Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Benzo(a)pyrene
Adverse Pharmacological Actions : Apoptotic, Neurotoxic
[+]

Aluminum bound to transferrin has low glomerular filtration.Jan 01, 1997

Pubmed Data : Crit Rev Clin Lab Sci. 1997 ;34(5):439-74. PMID: 9405895
Article Published Date : Jan 01, 1997
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Aluminum compounds surface as pro-inflammatory supra-adjuvants in autoimmune/inflammatory disease. Jan 31, 2012

Pubmed Data : Lupus. 2012 Feb ;21(2):231-8. PMID: 22235058
Article Published Date : Jan 31, 2012
Study Type : Review
Additional Links
Diseases : Inflammation
Problem Substances : Aluminum
[+]

Aluminum exposure and toxicity in neonates.Apr 30, 2014

Pubmed Data : World J Pediatr. 2014 May ;10(2):101-7. Epub 2014 May 7. PMID: 24801228
Article Published Date : Apr 30, 2014
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Infant Formula
[+]

Aluminum exposures during neonatal and pediatric parenteral nutrition can impair bone mineralization and delay neurological development.Sep 30, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Crit Rev Toxicol. 2014 Oct ;44 Suppl 4:1-80. PMID: 25233067
Article Published Date : Sep 30, 2014
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Aluminum oxide
[+]

Aluminum has been recurrently shown to cause encephalopathy and is connected to Alzheimer's disease.Jan 01, 2017

Pubmed Data : Adv Neurobiol. 2017 ;18:183-197. PMID: 28889268
Article Published Date : Jan 01, 2017
Study Type : Review
Additional Links
Diseases : Anemia, Encephalopathy, Neurodegenerative Diseases, Oxidative Stress
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum inclusion macrophagic myofasciitis: a recently identified condition.Oct 31, 2003

Pubmed Data : Immunol Allergy Clin North Am. 2003 Nov ;23(4):699-712. PMID: 14753387
Article Published Date : Oct 31, 2003
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis
Problem Substances : Aluminum Hydroxide
[+]

Aluminum ingestion is absorbed and may accumulate in different organs in both adults and infants.Oct 01, 1991

Pubmed Data : Rev Environ Health. 1991 Oct-Dec;9(4):191-205. PMID: 1842454
Article Published Date : Oct 01, 1991
Study Type : Review
Additional Links
Diseases : Dementia
Problem Substances : Aluminum, Infant Formula
[+]

Aluminum is implicated in Alzheimer's, ALS, and parkinsonism-dementia. Its accumulation occurs primarily in infants and children with immature or impaired renal function.Jun 01, 1990

Pubmed Data : Clin Lab Med. 1990 Jun ;10(2):403-22. PMID: 2197055
Article Published Date : Jun 01, 1990
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Amyotrophic lateral sclerosis (ALS), Kidney Failure: Chronic, Parkinson's Disease
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Bioaccumulator, Nephrotoxic, Neurotoxic
[+]

aluminum may induce apoptosis in astrocytes via ER stress by impairing the protein-folding machinery.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Prev Med. 2011 Jan ;16(1):16-24. Epub 2010 Jun 22. PMID: 21432213
Article Published Date : Dec 31, 2010
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Gene Expression
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum potentially enhanced apoptotic proteins and inflammatory markers in neuronal cells.Nov 06, 2015

Pubmed Data : Biol Trace Elem Res. 2015 Nov 7. Epub 2015 Nov 7. PMID: 26546554
Article Published Date : Nov 06, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Neurodegenerative Diseases
Problem Substances : Aluminum
Adverse Pharmacological Actions : Inflammatory, Neurotoxic
[+]

Aluminum toxicity may induce dyslipidemia and mitochondrial dysfunction in the liver through promotion of anaerobic metabolism, L-carnitine downregulation, and more.Oct 01, 2011

Pubmed Data : Exp Cell Res. 2011 Oct 1 ;317(16):2231-8. Epub 2011 Jul 20. PMID: 21787768
Article Published Date : Oct 01, 2011
Study Type : Review
Additional Links
Diseases : Dyslipidemias, Mitochondrial Dysfunction , Nonalcoholic fatty liver disease (NAFLD)
Additional Keywords : Vaccine Research
Problem Substances : Aluminum
Adverse Pharmacological Actions : Dyslipidemic, Hepatotoxic, Hypoxia, Oxidant
[+]

Aluminum's toxic effects may be due to its ability to displace other essential metals.Jan 01, 2000

Pubmed Data : Przegl Lek. 2000 ;57(11):665-8. PMID: 11293216
Article Published Date : Jan 01, 2000
Study Type : Review
Additional Links
Problem Substances : Aluminum
Adverse Pharmacological Actions : Cytotoxic, Neurotoxic
[+]

Aluminum-induced electrophysiological variation, synaptic plasticity impairment, and related mechanism.Dec 31, 2017

Pubmed Data : Adv Exp Med Biol. 2018 ;1091:161-172. PMID: 30315454
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Aluminum-induced entropy in biological systems: implications for neurological disease.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol. 2014 ;2014:491316. Epub 2014 Oct 2. PMID: 25349607
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Glyphosate, Lead
[+]

Aluminum-induced neural cell death.Dec 31, 2017

Pubmed Data : Adv Exp Med Biol. 2018 ;1091:129-160. PMID: 30315453
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease
Problem Substances : Aluminum
[+]

An up-to-date view of the catecholamine biosynthesis pathway with sites of aluminum interference is presented.Jan 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dalton Trans. 2019 Jan 28. Epub 2019 Jan 28. PMID: 30688329
Article Published Date : Jan 27, 2019
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease, Neurodegenerative Diseases
Problem Substances : Aluminum
[+]

Asiatic acid nullified aluminium toxicity in in vitro model of Alzheimer's disease.Dec 31, 2017

Pubmed Data : Front Biosci (Elite Ed). 2018 Jan 1 ;10:287-299. Epub 2018 Jan 1. PMID: 28930619
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Gotu Kola
Diseases : Alzheimer's Disease
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Both aluminium hydroxide and calcium phosphate exert local tissue irritating effects through damaging macrophages and increasing inflammation.Aug 01, 1997

Pubmed Data : Vaccine. 1997 Aug-Sep;15(12-13):1364-71. PMID: 9302746
Article Published Date : Aug 01, 1997
Study Type : In Vitro Study
Additional Links
Problem Substances : Aluminum Hydroxide, Calcium Phosphate
Adverse Pharmacological Actions : Cytotoxic, Inflammatory, Irritant
[+]

Brain aluminum entry from the blood may involve transferrin-receptor mediated endocytosis and not all aluminum that enters the brain is effluxed as aluminum citrate.Oct 01, 2000

Pubmed Data : Neurotoxicology. 2000 Oct ;21(5):813-28. PMID: 11130287
Article Published Date : Oct 01, 2000
Study Type : Review
Additional Links
Diseases : Neurodegenerative Diseases
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Cytotoxic, Neurotoxic
[+]

Brain translocation of aluminum particles is linked to a trojan horse mechanism previously described for infectious particles.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2015 ;6:4. Epub 2015 Feb 5. PMID: 25699008
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Autoimmune Diseases, Macrophagic myofasciitis
Additional Keywords : Biopersistence, Genomic Variation, Gulf War Syndrome, Risk Factors
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide
Adverse Pharmacological Actions : Neurotoxic
[+]

Chlorogenic acid has neuroprotective effects against aluminium-induced cytotoxicity by chelation and antioxidant activation.Jul 25, 2017

Pubmed Data : Food Funct. 2017 Jul 26. Epub 2017 Jul 26. PMID: 28745369
Article Published Date : Jul 25, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Antioxidants, Chelating Agents, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Clinical features in patients with long-lasting macrophagic myofasciitis.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2014 ;5:230. Epub 2014 Nov 28. PMID: 25506338
Article Published Date : Dec 31, 2013
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis
Problem Substances : Aluminum Hydroxide
[+]

Cross talk between aluminum and genetic susceptibility and epigenetic modification in Alzheimer's disease.Dec 31, 2017

Pubmed Data : Adv Exp Med Biol. 2018 ;1091:173-191. PMID: 30315455
Article Published Date : Dec 31, 2017
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease
Additional Keywords : Epigenetic Modification
Problem Substances : Aluminum
[+]

Curcumin had therapeutic effects against aluminium-induced neurotoxicity.Jun 28, 2019

Pubmed Data : Neurochem Res. 2019 Jun 29. Epub 2019 Jun 29. PMID: 31264110
Article Published Date : Jun 28, 2019
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Curcumin has a potential anti-inflammatory action against aluminum exposure.Feb 29, 2012

Pubmed Data : Neurochem Res. 2012 Mar ;37(3):639-46. Epub 2011 Dec 1. PMID: 22130689
Article Published Date : Feb 29, 2012
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Aluminum Toxicity , Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Aluminum
[+]

Deficits in the proline-rich synapse-associated shank3 protein in multiple neuropsychiatric disorders.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2017 ;8:670. Epub 2017 Dec 11. PMID: 29321759
Article Published Date : Dec 31, 2016
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Autism Spectrum Disorders, Bipolar Disorder
Problem Substances : Aluminum
[+]

Dementia in patients undergoing long-term dialysis: aetiology, differential diagnoses, epidemiology and management.Dec 31, 2000

Pubmed Data : CNS Drugs. 2001 ;15(9):691-9. PMID: 11580308
Article Published Date : Dec 31, 2000
Study Type : Commentary
Additional Links
Diseases : Dementia
Problem Substances : Aluminum
[+]

Febrile reaction was noted in approximately 60% of the children given alum-adjuvanted whole virion inactivated H5N1 vaccine. Jan 01, 2011

Pubmed Data : Yakugaku Zasshi. 2011 ;131(12):1723-31. PMID: 22129866
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Febrile Seizures, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Folic acid protected neuronal cells against aluminium maltolate induced apoptosis.Apr 24, 2016

Pubmed Data : Neurochem Res. 2016 Apr 25. Epub 2016 Apr 25. PMID: 27113042
Article Published Date : Apr 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Folic Acid
Diseases : Aluminum Toxicity
Pharmacological Actions : Anti-Apoptotic, MicroRNA modulator, Neuroprotective Agents
Problem Substances : Aluminum
[+]

Higher concentrations of BPA were detected in the solid fraction of canned food compared to their liquid fraction.Nov 28, 2016

Pubmed Data : Food Addit Contam Part B Surveill. 2016 Nov 29. Epub 2016 Nov 29. PMID: 27897085
Article Published Date : Nov 28, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Bisphenol Toxicity
Additional Keywords : Risk Factors
Problem Substances : Aluminium Cans, Bisphenol A
[+]

How aluminum adjuvants could promote and enhance non-target IgE synthesis in a genetically-vulnerable sub-population.Mar 31, 2013

Pubmed Data : J Immunotoxicol. 2013 Apr-Jun;10(2):210-22. Epub 2012 Sep 11. PMID: 22967010
Article Published Date : Mar 31, 2013
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Additional Keywords : Genomic Variation
Problem Substances : Aluminum
[+]

HPV vaccinations have not been clinically proven to prevent cervical cancer, that of which has an extremely low mortality rate and can be prevented by routine papsmears, and the risks associated with its administration may outweigh its benefits.Mar 01, 2013

Pubmed Data : Ann Med. 2013 Mar ;45(2):182-93. Epub 2011 Dec 22. PMID: 22188159
Article Published Date : Mar 01, 2013
Study Type : Review
Additional Links
Diseases : Cervical Cancer, Female, Vaccine-induced Toxicity
Additional Keywords : Autoimmunity, Vaccine Research
Anti Therapeutic Actions : Vaccination: HPV (Gardasil)
Problem Substances : Aluminum
[+]

Human health risk assessment for aluminium, aluminium oxide, and aluminium hydroxide.Dec 31, 2006

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Toxicol Environ Health B Crit Rev. 2007 ;10 Suppl 1:1-269. PMID: 18085482
Article Published Date : Dec 31, 2006
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Problem Substances : Aluminum, Aluminum oxide
[+]

Hydrogen-rich water alleviates aluminum-induced inhibition of root elongation in alfalfa.Feb 27, 2014

Pubmed Data : J Hazard Mater. 2014 Feb 28 ;267:40-7. Epub 2013 Dec 27. PMID: 24413050
Article Published Date : Feb 27, 2014
Study Type : Plant Study
Additional Links
Substances : Alfalfa, Hydrogen Water
Problem Substances : Aluminum
[+]

Hydrogen-rich water induces aluminum tolerance in maize seedlings by enhancing antioxidant capacities and nutrient homeostasis.Sep 30, 2017

Pubmed Data : Ecotoxicol Environ Saf. 2017 Oct ;144:369-379. Epub 2017 Jun 22. PMID: 28647604
Article Published Date : Sep 30, 2017
Study Type : Plant Study
Additional Links
Substances : Hydrogen Water
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants
Problem Substances : Aluminum
[+]

Immediate steps should be taken to lessen human exposure to aluminum, which may be the single most aggravating and avoidable factor related to Alzheimer's disease.Jan 01, 2011

Pubmed Data : J Alzheimers Dis. 2011 ;23(4):567-98. PMID: 21157018
Article Published Date : Jan 01, 2011
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Immunization with aluminum adjuvants can be viewed as an amplifying factor and significant contributing risk factor for allergic diseases, especially in a genetically susceptible subpopulation.Jan 03, 2018

Pubmed Data : Int J Environ Res Public Health. 2018 05 3 ;15(5). Epub 2018 May 3. PMID: 29751492
Article Published Date : Jan 03, 2018
Study Type : Review
Additional Links
Diseases : Allergies
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

In the presence of a favourable genetic background, many autoimmune/inflammatory responses can be triggered by adjuvants.Nov 30, 2014

Pubmed Data : Immunol Res. 2014 Dec ;60(2-3):366-75. PMID: 25395340
Article Published Date : Nov 30, 2014
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Infant formula contains high levels of aluminium. Jan 01, 2010

Pubmed Data : BMC Pediatr. 2010;10:63. Epub 2010 Aug 31. PMID: 20807425
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Infant Chemical Exposures, Infant Nutrition: Infant Formula
Problem Substances : Aluminum, Infant Formula
[+]

Injection of aluminum hydroxide results in an immediate increase in its bioavailability.Mar 01, 2010

Pubmed Data : Trends Immunol. 2010 Mar ;31(3):103-9. Epub 2010 Feb 10. PMID: 20153253
Article Published Date : Mar 01, 2010
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Inflammation
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Insight into the cellular fate and toxicity of aluminium adjuvants used in clinically approved human vaccinations.Aug 11, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2016 Aug 12 ;6:31578. Epub 2016 Aug 12. PMID: 27515230
Article Published Date : Aug 11, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

It is hypothesized, in the present review, that Al is a potential factor for induction or maintaining the inflammation in Crohn's disease.May 31, 2007

Pubmed Data : Ann N Y Acad Sci. 2007 Jun ;1107:329-45. PMID: 17804561
Article Published Date : May 31, 2007
Study Type : Review
Additional Links
Diseases : Crohn's Disease
Additional Keywords : Genomic Variation, Risk Factors
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration.Dec 10, 2015

Pubmed Data : Neurotoxicology. 2015 Dec 11. Epub 2015 Dec 11. PMID: 26687397
Article Published Date : Dec 10, 2015
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Brain Inflammation , Neurodegenerative Diseases
Problem Substances : Aluminum
Adverse Pharmacological Actions : Inflammatory
[+]

Macrophagic myofasciitis has been reported following vaccination and is attributed to the aluminium hydroxide.Oct 31, 2009

Pubmed Data : Lupus. 2009 Nov ;18(13):1213-6. PMID: 19880571
Article Published Date : Oct 31, 2009
Study Type : Review
Additional Links
Diseases : Myopathies, Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
[+]

Macrophagic myofasciitis may be defined as an emerging novel condition that may be triggered by exposure to alum-containing vaccines.Sep 30, 2011

Pubmed Data : Clin Rev Allergy Immunol. 2011 Oct ;41(2):163-8. PMID: 20882368
Article Published Date : Sep 30, 2011
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum
[+]

Maternal exposure to excess aluminum can lead to neurobehavioral deficits in offspring, according to animal studies.Jul 01, 1995

Pubmed Data : Neurotoxicol Teratol. 1995 Jul-Aug;17(4):515-21. PMID: 7565498
Article Published Date : Jul 01, 1995
Study Type : Review
Additional Links
Additional Keywords : Pregnancy
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

More research attention has been given to EtHg and findings have showed a solid link with neurotoxic effects in humans.Jan 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2015 Feb ;12(2):1295-313. Epub 2015 Jan 23. PMID: 25625408
Article Published Date : Jan 31, 2015
Study Type : Review
Additional Links
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Thimerosal
[+]

Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture.Aug 31, 2005

Pubmed Data : J Inorg Biochem. 2005 Sep ;99(9):1895-8. PMID: 15961160
Article Published Date : Aug 31, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Brain Inflammation
Problem Substances : Aluminum
[+]

Neurological adverse events associated with vaccination.May 31, 2002

Pubmed Data : Curr Opin Neurol. 2002 Jun ;15(3):333-8. PMID: 12045734
Article Published Date : May 31, 2002
Study Type : Review
Additional Links
Diseases : Autism, Guillain-Barre Syndrome, Multiple Sclerosis, New Variant Creutzfeldt-Jakob Disease, Vaccine-induced Toxicity
Additional Keywords : Adverse Events, Vaccine Contaminants
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Thimerosal
[+]

Neuroprotective role of hyperforin on aluminum maltolate-induced oxidative damage and apoptosis in PC12 cells and SH-SY5Y cells.Nov 23, 2018

Pubmed Data : Chem Biol Interact. 2018 Nov 24 ;299:15-26. Epub 2018 Nov 24. PMID: 30481499
Article Published Date : Nov 23, 2018
Study Type : In Vitro Study
Additional Links
Substances : Hyperforin, St. Johns Wort
Diseases : Aluminum Toxicity
Pharmacological Actions : Neuroprotective Agents
Problem Substances : Aluminum
[+]

Our preliminary results demonstrate behavioural and neurochemical alterations in the offspring of mice exposed to aluminium during gestation.Dec 31, 1992

Pubmed Data : Ann Ist Super Sanita. 1993 ;29(1):147-52. PMID: 8129261
Article Published Date : Dec 31, 1992
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Prenatal Chemical Exposures
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

Physiologically relevant amounts of iron and aluminum are capable of inducing Fenton chemistry-triggered gene expression.Oct 31, 2005

Pubmed Data : J Alzheimers Dis. 2005 Nov ;8(2):117-27; discussion 209-15. PMID: 16308480
Article Published Date : Oct 31, 2005
Study Type : In Vitro Study
Additional Links
Diseases : Aluminum Toxicity , Alzheimer's Disease, Inflammation
Additional Keywords : Gene Expression
Problem Substances : Aluminum
[+]

Presently, no population-based studies regarding the potential association between the Al in vaccines and the development of neurotoxicity have been conducted and we cannot draw firm conclusions about their safety.Jan 18, 2018

Pubmed Data : Vaccine. 2018 09 18 ;36(39):5825-5831. Epub 2018 Aug 20. PMID: 30139653
Article Published Date : Jan 18, 2018
Study Type : Review
Additional Links
Diseases : Chronic Fatigue Syndrome, Neurodegenerative Diseases
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Prolonged exposure to low levels of aluminum leads to changes associated with brain aging and neurodegeneration.Jan 05, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxicology. 2014 Jan 6 ;315:1-7. Epub 2013 Nov 1. PMID: 24189189
Article Published Date : Jan 05, 2014
Study Type : Review
Additional Links
Diseases : Aging, Aluminum Toxicity , Neurodegenerative Diseases, Vaccine-induced Toxicity
Problem Substances : Aluminum
[+]

Recent studies implicate a web of mechanisms in the development of vaccine adjuvant-induced autoimmune diseases.Sep 30, 2015

Pubmed Data : Autoimmun Rev. 2015 Oct ;14(10):880-8. Epub 2015 May 29. PMID: 26031899
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Autoimmune Diseases, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

Sweat gland obstruction via the use of aluminium-containing antiperspirants may be contributing to increased incidence of prostate and breast cancer.Jun 01, 2009

Pubmed Data : Med Hypotheses. 2009 Jun ;72(6):665-74. PMID: 19307063
Article Published Date : Jun 01, 2009
Study Type : Review
Additional Links
Diseases : Breast Cancer, Prostate Cancer
Additional Keywords : Sweat Gland Obstruction
Problem Substances : Aluminum, Antiperspirants
Adverse Pharmacological Actions : Carcinogenic, Endocrine Disruptor
[+]

Synergism in aluminum and mercury neurotoxicity.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Integr Food Nutr Metab. 2018 May ;5(3). Epub 2018 Apr 13. PMID: 29938114
Article Published Date : Apr 30, 2018
Study Type : In Vitro Study
Additional Links
Additional Keywords : Synergistic Toxicity
Problem Substances : Aluminum, Mercury
Adverse Pharmacological Actions : Inflammatory, Neurotoxic
[+]

The evolution of modern human beings began in the absence of biologically available aluminum and is now progressing in an age where it is the most ubiquitous and abundant ecotoxin on Earth.Jan 01, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurol. 2014 ;5:212. Epub 2014 Oct 27. PMID: 25386158
Article Published Date : Jan 01, 2014
Study Type : Review
Additional Links
Diseases : Alzheimer's Disease, Neurodegenerative Diseases
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

The neurotoxicity of environmental aluminum is still an issue.Aug 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neurotoxicology. 2010 Sep ;31(5):575-81. Epub 2010 May 27. PMID: 20553758
Article Published Date : Aug 31, 2010
Study Type : Review
Additional Links
Diseases : Brain Inflammation , Neurodegenerative Diseases
Problem Substances : Aluminum
[+]

The present study provides an insight on the molecular role of genistein and chickpea extract as protective agents against neuronal injury.Aug 31, 2017

Pubmed Data : Food Chem Toxicol. 2017 Sep ;107(Pt A):57-67. Epub 2017 May 24. PMID: 28552514
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Chickpea, Genistein
Diseases : Aluminum Toxicity , Neurodegenerative Diseases, Oxidative Stress
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation, Plant Extracts
Problem Substances : Aluminum
[+]

The putative role of environmental aluminium in the development of chronic neuropathology in adults and children. Jan 09, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Metab Brain Dis. 2017 10 ;32(5):1335-1355. Epub 2017 Jul 27. PMID: 28752219
Article Published Date : Jan 09, 2017
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Neurodegenerative Diseases
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

The review summarizes various hypotheses that link aluminum to neurodegeneration.Jan 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Res Med Sci. 2018 ;23:51. Epub 2018 Jun 6. PMID: 30057635
Article Published Date : Jan 01, 2018
Study Type : Review
Additional Links
Diseases : Neurodegenerative Diseases, Neurologic Disorders
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

The risk of aluminum vaccine adjuvants may be greatly underestimated. May 16, 2011

Pubmed Data : Curr Med Chem. 2011 May 16. Epub 2011 May 16. PMID: 21568886
Article Published Date : May 16, 2011
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Immunotoxic
[+]

There are several case reports of autoimmune diseases following vaccines.Sep 30, 2015

Pubmed Data : Pharmacol Res. 2015 Oct ;100:190-209. Epub 2015 Aug 12. PMID: 26275795
Article Published Date : Sep 30, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Vaccine-induced Toxicity
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

There are several environmental factors associated with the development of ASD, including pesticides, phthalates, polychlorinated biphenyls, solvents, air pollutants, fragrances, glyphosate and heavy metals, especially aluminum used in vaccines.Mar 01, 2016

Pubmed Data : Environ Int. 2016 Mar ;88:288-298. Epub 2016 Jan 28. PMID: 26826339
Article Published Date : Mar 01, 2016
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders
Additional Keywords : Heavy Metals and Autism, Vaccine Research
Problem Substances : Aluminum, Glyphosate, Heavy Metals, Pesticides, Phthalates, Polychlorinated biphenyls (PCBs), Synthetic Fragrance, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

This article describes aluminum hydroxide adjuvants as safe, citing a guinea pig study that only looked at anaphylactic reactions.Jan 01, 2015

Pubmed Data : Hum Vaccin Immunother. 2015 ;11(2):477-88. PMID: 25692535
Article Published Date : Jan 01, 2015
Study Type : Review
Additional Links
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum Hydroxide, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

This paper outlines sources of aluminum exposure and the tolerable weekly intake.Jan 01, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Sci Eur. 2017 ;29(1):19. Epub 2017 Apr 12. PMID: 28458989
Article Published Date : Jan 01, 2017
Study Type : Review
Additional Links
Problem Substances : Aluminum
Adverse Pharmacological Actions : Bioaccumulator, Neurotoxic
[+]

This review concludes that chronic adjuvant stimulation may lead to lymphoma. Jan 31, 2015

Pubmed Data : Immunol Res. 2015 Feb ;61(1-2):79-89. PMID: 25582758
Article Published Date : Jan 31, 2015
Study Type : Review
Additional Links
Diseases : Autoimmune/inflammatory syndrome induced by adjuvants (ASIA), Inflammation, Lymphoma
Additional Keywords : Risk Factors
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

This review delineates the role of aluminum in some human diseases, specifically bone and neurodegenerative diseases.Feb 01, 2013

Pubmed Data : Biomol Concepts. 2013 Feb ;4(1):77-87. PMID: 25436567
Article Published Date : Feb 01, 2013
Study Type : Review
Additional Links
Diseases : Bone Diseases, Neurodegenerative Diseases
Additional Keywords : Vaccine Research
Problem Substances : Aluminum
Adverse Pharmacological Actions : Neurotoxic
[+]

This review demonstrates the pitfalls of various studies attempting to establish the safety of aluminum adjuvants.Jul 01, 2017

Pubmed Data : Ann Pharm Fr. 2017 Jul ;75(4):245-256. Epub 2017 May 31. PMID: 28576261
Article Published Date : Jul 01, 2017
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Aluminum Hydroxide, Vaccine Adjuvants
[+]

This review describes the cellular metabolism of aluminum ions and how they relate to neurodegeneration.Mar 01, 1986

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 1986 Mar ;65:363-441. PMID: 2940082
Article Published Date : Mar 01, 1986
Study Type : Review
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Brain Inflammation
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This review describes the cellular metabolism of aluminum ions and how they relate to neurodegeneration.Mar 01, 1986

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 1986 Mar ;65:363-441. PMID: 2940082
Article Published Date : Mar 01, 1986
Study Type : Review
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Brain Inflammation
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This review describes the cellular metabolism of aluminum ions and how they relate to neurodegeneration.Mar 01, 1986

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Environ Health Perspect. 1986 Mar ;65:363-441. PMID: 2940082
Article Published Date : Mar 01, 1986
Study Type : Review
Additional Links
Diseases : Amyotrophic Lateral Sclerosis, Brain Inflammation
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This review describes the reactions between toxic and essential metals, specifically how heavy metals can displace and disrupt the function of essential minerals.Jan 01, 1997

Pubmed Data : Annu Rev Nutr. 1997 ;17:37-50. PMID: 9240918
Article Published Date : Jan 01, 1997
Study Type : Review
Additional Links
Diseases : Lead Poisoning, Mercury Poisoning
Problem Substances : Aluminum, Cadmium, Heavy Metals, Lead
Adverse Pharmacological Actions : Neurotoxic
[+]

This review describes vaccine hypersensitivity.May 01, 2012

Pubmed Data : Dermatitis. 2012 May-Jun;23(3):102-9. PMID: 22653170
Article Published Date : May 01, 2012
Study Type : Review
Additional Links
Diseases : Vaccine-induced Toxicity , vaccine injury
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : 2-phenoxyethanol, Aluminum, Formaldehyde, Mercury, Neomycin, Thimerosal
[+]

This review emphasizes the paucity of research on aluminum transport in the body, especially in the blood. Thus, the "indisputable" pharmacokinetics of aluminum in vaccine research is likely unfounded.Apr 01, 2015

Pubmed Data : J Trace Elem Med Biol. 2015 Apr ;30:90-5. Epub 2014 Nov 20. PMID: 25498314
Article Published Date : Apr 01, 2015
Study Type : Review
Additional Links
Additional Keywords : Vaccine Research
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
[+]

This review focuses on the roles and mechanisms of action of different adjuvants which lead to the autoimmune/inflammatory response that leads to the autoimmune syndrome induced by adjuvants (ASIA).Dec 01, 2013

Pubmed Data : J Autoimmun. 2013 Dec ;47:1-16. Epub 2013 Nov 13. PMID: 24238833
Article Published Date : Dec 01, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune Diseases, Autoimmune Syndrome Induced by Adjuvants (ASIA), Inflammation
Additional Keywords : Blood Brain Barrier, Iatrogenic Disease
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum, Vaccine Adjuvants
Adverse Pharmacological Actions : Inflammatory
[+]

This review outlines the toxicity of chronic aluminum exposure.Jun 01, 2016

Pubmed Data : Morphologie. 2016 Jun ;100(329):51-5. Epub 2016 Feb 28. PMID: 26922890
Article Published Date : Jun 01, 2016
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity , Breast Cancer
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This review provides an overview of heavy metals as neurotoxins and their relevance to neurological diseases. The author also indicates that neurotoxin-free vaccine adjuvants are prudent.Jan 05, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Environ Res Public Health. 2017 12 5 ;14(12). Epub 2017 Dec 5. PMID: 29206191
Article Published Date : Jan 05, 2017
Study Type : Review
Additional Links
Diseases : Female, Neurodegenerative Diseases
Additional Keywords : Vaccine Research
Problem Substances : Aluminum, Heavy Metals, Lead, Mercury, Vaccine Adjuvants
Adverse Pharmacological Actions : Neurotoxic
[+]

This review provides evidence for the effects of aluminum on the immune system.Jan 01, 2013

Pubmed Data : Environ Toxicol Pharmacol. 2013 Jan ;35(1):82-7. Epub 2012 Nov 26. PMID: 23274174
Article Published Date : Jan 01, 2013
Study Type : Review
Additional Links
Diseases : Autoimmune Syndrome Induced by Adjuvants (ASIA)
Additional Keywords : Autoimmunity, Vaccine Research
Problem Substances : Aluminum
Adverse Pharmacological Actions : Immunotoxic
[+]

This study advises that all patients should receive information on the detrimental effects of aluminum in over-the-counter drugs, particularly pregnant women.Jan 01, 2003

Pubmed Data : Drug Saf. 2003 ;26(14):1011-25. PMID: 14583063
Article Published Date : Jan 01, 2003
Study Type : Review
Additional Links
Problem Substances : Aluminum, Antacids: Aluminium-Containing
Adverse Pharmacological Actions : Abortive, Neurotoxic
[+]

This study rightfully criticizes the poor methodology of aluminum adjuvant safety studies.Jan 01, 2018

Pubmed Data : J Inorg Biochem. 2018 04 ;181:87-95. Epub 2017 Dec 28. PMID: 29307441
Article Published Date : Jan 01, 2018
Study Type : Review
Additional Links
Diseases : Aluminum Toxicity
Anti Therapeutic Actions : Vaccination: All
Problem Substances : Aluminum
[+]

This study shows that inhibition of methionine synthase(MS) activity by ethanol, lead, mercury, aluminum and thimerosal suggesting that it may be an important target of neurodevelopmental toxins.Mar 31, 2004

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Psychiatry. 2004 Apr ;9(4):358-70. PMID: 14745455
Article Published Date : Mar 31, 2004
Study Type : In Vitro Study
Additional Links
Diseases : Attention Deficit Disorder, Autism Spectrum Disorders, Neurodevelopmental Disorders
Problem Substances : Aluminum, Ethanol, Lead, Thimerosal
Adverse Pharmacological Actions : Hypermethylation
[+]

This study suggests that excitotoxicity may be the central mechanism of autism spectrum disorders and that excitotoxins like aluminum, fluoride, and mercury may exacerbate excitotoxicity.Jan 01, 2009

Pubmed Data : Curr Med Chem. 2009 ;16(2):157-70. PMID: 19149568
Article Published Date : Jan 01, 2009
Study Type : Review
Additional Links
Diseases : Autism, Autism Spectrum Disorders, Brain: Microglial Activation, Heavy Metal Toxicity
Additional Keywords : Heavy Metals and Autism, Vaccine Research
Problem Substances : Aluminum, Fluoride, Mercury
Adverse Pharmacological Actions : Excitotoxic, Neurotoxic
[+]

Vaccination with adjuvants may be responsible for a number of disorders. Feb 01, 2003

Pubmed Data : Rev Neurol (Paris). 2003 Feb;159(2):162-4. PMID: 12660567
Article Published Date : Feb 01, 2003
Study Type : Commentary
Additional Links
Diseases : Chronic Fatigue Syndrome, Fibromyalgia, Gulf War Syndrome, Macrophagic myofasciitis , Vaccine-induced Toxicity
Problem Substances : Aluminum Hydroxide

Aluminum Related Articles

Scientists Researching the Effect of Aluminum Exposure Appeal to the Public
Written by Christina England, BA Hons
Aluminum has been linked to diseases such as cancer, autism, and Alzheimer's. This toxic material is entering the human body via everyday consumption of food, water, cosmetics and an increasing number of vaccinations.
High Aluminum Levels Contaminate Brains of Autistic Children
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Study Underscores Need for More Research to Determine Whether Vaccines Are the Source
The Root of Autoimmune Disease can be Found in the Gut
Written by GMI Reporter
Thanks to the Human Microbiome Project, we know that we are home to trillions of microbes, the largest number of which are found in our gut. And as in agriculture, diversity tends toward health
The Little Known Miracle of Life: Fulvic acid
Written by Erin Chamerlik, MS, MT(ASCP)
The microbes in the soil make the hidden treasure called fulvic acid, the miracle of life. Our bodies need it for optimal health. Fulvic acid is not a vitamin or a mineral and cannot be synthesized
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Written by GMI Reporter
Open Letter to the United States of America from Dr. Stefano Montanari
Anatomy of a Science Study Censorship
Written by Celeste McGovern
Elsevier's "withdrawal" of a small veterinary study breaks all the rules of scientific publishing. The biggest name in scientific literature has produced fake medical journals for Merck's advertisers before, so yanking a study that doesn't pass the vaccine industry's sniff test would be nothing. Celeste McGovern looks at a case study of how Pharma is killing science
Migraines Linked to Certain Heavy Metals and Mineral Deficiencies
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Discovering the cause of a migraine can be tricky. Triggers are not only difficult to find but often lead nowhere. A new study finds that certain heavy metals are linked to migraines, along with deficiences in certain minerals.
FDA approved Gardasil 9: Malfeasance or Stupidity?
Written by Norma Erickson
The FDA's approval of the new Gardasil vaccine, containing double the aluminum of the previous one, represents a heinous violation of the public interest.
Toxic...and Don't Know?
Written by Capt. Randall
Ever since humans discovered fire, our activities have been releasing a "dog's breakfast" of unnatural chemistry. The list has grown to well over 75,000 free elements, compounds and pharmaceuticals. Many of these are acidic, electron-hungry oxidants and free radical generators.
Who Needs Healthy Food When We Can Eat Cash? Codex Update
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The hazy, smoggy skies over Beijing during these March days are emblematic of the Codex meetings that the National Health Federation (NHF) has been attending for many days here in China.
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Shungite: The Electropollution Solution Special Report
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Failing Our Weakest Newborns: Poisoning with Aluminum
Written by Heidi Stevenson
In this first report from the Keele Conference on the biological effects of aluminum, we learn that the weakest among us, premature newborns and sickly elderly, are being poisoned with aluminum through their nutrition. The FDA’s aluminum limits are routinely ignored, while this problem, known for 30 years, continues unabated.
Vaccine Safety and Efficacy Studies That are the Bases for Marketing Authorizations are a Complete Methodological Mess
Written by Mateja Cernic
Claims that vaccines “undergo rigorous and extensive testing”, that they are “held to the highest standard of safety”, etc., are lies.
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Written by Rishma Parpia
Traditional toxicology relies on archaic methods that focus on the short term while ignoring the long term effects of repeated small doses over time
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Written by Heather Green
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New study: Vaccine Manufacturers and FDA Regulators Used Statistical Gimmicks to Hide Risks of HPV Vaccines
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Written by John P. Thomas
The clouds in the sky are not always natural, because they are often manufactured by specially equipped aircraft. These jets are spraying highly toxic particles of aluminum, barium, strontium, arsenic, and other substances to make clouds for weather-related and military purposes. These clouds are also harmful to humans and the environment.
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Written by Christina England, BA Hons
Depression is on the rise around the world and, according to one author, the World Health Organization (WHO) has stated that approximately 300 million people worldwide suffer from this debilitating disorder

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