Frankincense

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34 Diseases Researched for Frankincense
NameACCKFocus
Osteoarthritis: Knee550Locked
Brain Edema220Locked
Pain220Locked
Inflammation416Locked
Breast Cancer215Locked
Oxidative Stress314Locked
Arthritis212Locked
Cancers: All211Locked
Ulcerative Colitis211Locked
Advanced Glycation End products (AGE)110Locked
Aging Skin110Locked
Allergic Rhinitis110Locked
Anxiety Disorders110Locked
Asthma110Locked
Brain Inflammation 110Locked
Depression110Locked
Irritable Bowel Syndrome110Locked
Lipid Peroxidation110Locked
Bladder Cancer15Locked
Cancer Metastasis15Locked
Cognitive Decline/Dysfunction24Locked
Colon Cancer23Locked
Inflammatory Bowel Diseases33Locked
Cerebral Ischemia12Locked
Colon Cancer: Prevention12Locked
Diabetes Mellitus: Type 212Locked
Endothelial Dysfunction12Locked
Gastric Ulcer12Locked
Learning disorders12Locked
Memory Disorders12Locked
Pancreatic Cancer12Locked
Rheumatoid Arthritis12Locked
Crohn's Disease11Locked
Protozoan Infections11Locked
35 Pharmacological Actions Researched for Frankincense
NameACCKFocus
Anti-Inflammatory Agents1592Locked
Analgesics440Locked
Antioxidants626Locked
Apoptotic514Locked
Cyclooxygenase 2 Inhibitors212Locked
Anti-Allergic Agents110Locked
Anti-Asthmatic Agents110Locked
Antinoceceptive 110Locked
Cell cycle arrest210Locked
Chemotherapeutic110Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor110Locked
Photoprotective110Locked
Radioprotective110Locked
Neuroprotective Agents59Locked
Antiproliferative 38Locked
Immunomodulatory13Locked
Anticarcinogenic Agents12Locked
Brain-derived neurotrophic factor modulator12Locked
Chemopreventive12Locked
Gastroprotective12Locked
Gluconeogenesis Inhibitor12Locked
Interferon Gamma Reducer12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-12 downregulation12Locked
Interleukin-2 Downregulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
5-Lipoxygenase Inhibitor11Locked
Anti-metastatic11Locked
Antiprotozoal Agents11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
NF-kappaB Inhibitor11Locked
Prostaglandin PGE2 downregulation11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked

View the Evidence:
76 Abstracts with Frankincense Research

[+]

A Boswellia-based cream could be used for prevention of adjuvant radiotherapy skin damage in mammary carcinoma.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2015 Apr ;19(8):1338-44. PMID: 25967706
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic, Radioprotective
Additional Keywords : Plant Extracts
[+]

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213
Article Published Date : Oct 31, 2013
Study Type : Human Study
Additional Links
Substances : Frankincense, Turmeric
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Celecoxib, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

A Frankincense extract attenuates the symptoms associated with mild Ulcerative Colitis in remission.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Jun ;20(12):2695-700. PMID: 27383325
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

A herbal formulation is a safe and effective intervention for management of joint discomfort.Apr 30, 2018

Pubmed Data : J Med Food. 2018 May ;21(5):511-520. Epub 2018 Apr 30. PMID: 29708818
Article Published Date : Apr 30, 2018
Study Type : Human Study
Additional Links
Substances : Frankincense, Haritaki (Terminalia chebula), Turmeric
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

Pubmed Data : J Altern Complement Med. 2017 Aug ;23(8):632-638. Epub 2017 Apr 4. PMID: 28375641
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Kidney Disease (CKD), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Administration of Boswellia serrate extract with a high fat meal boosted boswellic acid levels. Nov 30, 2004

Pubmed Data : Planta Med. 2004 Dec ;70(12):1155-60. PMID: 15643550
Article Published Date : Nov 30, 2004
Study Type : Human Study
Additional Links
Substances : Frankincense
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Aflapin exhibited better efficacy compared to 5-Loxin to reduce pain and improve physical functions significantly in OA subjects.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2010 ;7(6):366-77. Epub 2010 Nov 1. PMID: 21060724
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Plant Extracts
[+]

Benefits of a food supplement containing Boswellia serrata and bromelain for improving the quality of life in patients with osteoarthritis.Oct 31, 2019

Pubmed Data : J Altern Complement Med. 2019 Nov 1. Epub 2019 Nov 1. PMID: 31674795
Article Published Date : Oct 31, 2019
Study Type : Human Study
Additional Links
Substances : Bromelain, Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Osteoprotective
[+]

Boswellia serrata Extract could be recommended in patients of osteoarthritis of the knee with possible therapeutic use in other arthritis.Dec 31, 2002

Pubmed Data : Phytomedicine. 2003 Jan ;10(1):3-7. PMID: 12622457
Article Published Date : Dec 31, 2002
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Arthritis, Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Boswellia serrata significantly increased the pain threshold and pain tolerance force and time compared to baseline and placebo.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2014 Sep-Oct;46(5):475-9. PMID: 25298573
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Pain
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Boswellia serrata significantly reduced cerebral edema measured by MRI in the study population.Aug 14, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer. 2011 Aug 15 ;117(16):3788-95. Epub 2011 Feb 1. PMID: 21287538
Article Published Date : Aug 14, 2011
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Brain Edema, Cancers: All
Therapeutic Actions : Placebo Effect
Additional Keywords : Medication Reduction, Phytotherapy
Problem Substances : Dexamethasone, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.Dec 14, 2011

Pubmed Data : J Pharm Biomed Anal. 2011 Dec 15 ;56(5):998-1005. Epub 2011 Jul 29. PMID: 21855244
Article Published Date : Dec 14, 2011
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Brain Edema, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Casperome supplementation could represent a promising alternative approach to manage symptoms associated with IBS.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2017 May ;21(9):2249-2254. PMID: 28537656
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Irritable Bowel Syndrome
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Constitutes of Boswellia serrata extract act synergistically to exert anti-inflammatory/anti-arthritic activity.Mar 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Mar 6. Epub 2019 Mar 6. PMID: 30838706
Article Published Date : Mar 05, 2019
Study Type : Human Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substance Synergy
[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642
Article Published Date : Nov 20, 2016
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Essential oil hand massage was used with hospice patients with terminal cancer with a positive effect on pain and depression.Jul 31, 2008

Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801
Article Published Date : Jul 31, 2008
Study Type : Human Study
Additional Links
Substances : Bergamot, Frankincense, Lavender
Diseases : Anxiety Disorders, Depression, Pain
Therapeutic Actions : Aromatherapy Massage
[+]

Inhalation of aromatherapy essential oil may have potential as an effective intervention to alleviate perennial allergic rhinitis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:7896081. Epub 2016 Mar 13. PMID: 27034695
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense, Sandalwood
Diseases : Allergic Rhinitis
Therapeutic Actions : Aromatherapy
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Essential Oils
[+]

Interference with catG could explain some of the anti-inflammatory properties of frankincense.Aug 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol. 2009 Sep 1 ;183(5):3433-42. Epub 2009 Jul 31. PMID: 19648270
Article Published Date : Aug 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritisFeb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2016 Mar ;29(1):140-6. Epub 2015 Dec 18. PMID: 26684635
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense, MSM (Methylsulfonylmethane)
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Supplementation with Boswellia had beneficial effects on pain, stiffness and physical functions in patients with symptomatic knee osteoarthritis.Nov 30, 2014

Pubmed Data : Minerva Med. 2014 Dec ;105(6 Suppl 2):9-16. PMID: 26076376
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The Boswellia serrate and lemon balm tablet in older adults can be beneficial on improvement of memory.Mar 31, 2018

Pubmed Data : Arch Gerontol Geriatr. 2018 Mar - Apr;75:146-150. Epub 2017 Dec 28. PMID: 29306113
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Substances : Frankincense, Lemon Balm
Diseases : Cognitive Decline/Dysfunction, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

The use of Boswellia phytosome extracts are beneficial for asthmatic patients as it helps reduce the need for inhalation therapy.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2015 Oct ;19(19):3757-62. PMID: 26502867
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents
[+]

These preliminary results indicate the efficacy and safety of Movardol supplementation in the management of moderate knee osteoarthritis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Dec ;20(24):5198-5204. PMID: 28051248
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense, Ginger
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Topical application of boswellic acids may represent a suitable treatment option for selected features of skin photoaging.Dec 31, 2009

Pubmed Data : Dermatol Ther. 2010 Jan-Feb;23 Suppl 1:S28-32. PMID: 20136919
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Aging Skin
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Extracts
[+]

Twelve-week use of curcumin complex or its combination with boswellic acid reduces pain-related symptoms in patients with osteoarthritis.Jan 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Jan 9 ;18(1):7. Epub 2018 Jan 9. PMID: 29316908
Article Published Date : Jan 08, 2018
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Analgesics
Additional Keywords : Natural Substance Synergy
[+]

Human bladder cancer cells and immortalized normal bladder cells were studied using Frankincense oil; Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2009 ;9:6. Epub 2009 Mar 18. PMID: 19296830
Article Published Date : Dec 31, 2008
Study Type : Human In Vitro
Additional Links
Substances : Frankincense
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2011 ;11:129. Epub 2011 Dec 15. PMID: 22171782
Article Published Date : Dec 31, 2010
Study Type : Human In Vitro
Additional Links
Substances : Frankincense
Diseases : Breast Cancer, Cancer Metastasis
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Selective Cytotoxicity
[+]

This article describes one patient's experience using frankincense (Boswellia carterii) essential oil to help in the management of her fatigue.Dec 31, 2017

Pubmed Data : Holist Nurs Pract. 2018 May/Jun;32(3):140-142. PMID: 29642127
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report
Additional Links
Substances : Frankincense
Diseases : Cancer: Fatigue
[+]

A plant mixture comprising Nigella sativa, Myrrh, Gum Olibanum (Frankincense), Gum Asafoetida and Aloe lowers blood sugar by inhibiting hepatis gluconeogenesis. Dec 01, 1991

Pubmed Data : Diabetes Res. 1991 Dec;18(4):163-8. PMID: 1842751
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Asafoetida, Frankincense, Myrrh, Nigella sativa (aka Black Seed)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Gluconeogenesis Inhibitor
Additional Keywords : Plant Extracts
[+]

Acetyl-11-keto-β-boswellic acid extracted from Boswellia serrata promotes Schwann cell proliferation and sciatic nerve function recovery.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2018 Mar ;13(3):484-491. PMID: 29623934
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

Administration of Boswellia resin in aged Wistar ratd was able to improve learning capability.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2016 Mar-Apr;6(2):189-97. PMID: 27222832
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Anti-inflammatory and anti-arthritic effects of methanol extract of the stem bark of Boswellia dalzielii.Nov 30, 2018

Pubmed Data : Inflammopharmacology. 2018 Dec ;26(6):1383-1398. Epub 2018 Jun 13. PMID: 29948494
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Boswellia sacra and folic acid attenuated the neurodegenerative effects of EMF in the hippocampus and cerebellum.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microsc Ultrastruct. 2017 Oct-Dec;5(4):216-224. Epub 2017 Sep 18. PMID: 30023257
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Frankincense
Diseases : Mobile Phone-Induced Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Radioprotective
Anti Therapeutic Actions : Mobile Phone Radiation
[+]

Boswellia serrata extract might have usefulness as an adjunct to conventional therapy of rheumatoid arthritis.Mar 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):100-106. PMID: 31041173
Article Published Date : Mar 31, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents
[+]

Boswellia serrata gum resin aqueous extract upregulates BDNF.Nov 16, 2016

Pubmed Data : Turk J Med Sci. 2016 Nov 17 ;46(5):1573-1578. Epub 2016 Nov 17. PMID: 27966331
Article Published Date : Nov 16, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Learning disorders
Pharmacological Actions : Brain-derived neurotrophic factor modulator
[+]

Boswellia serrate extract has great potential to suppress colon tumorigenesis.Feb 27, 2017

Pubmed Data : Mol Nutr Food Res. 2017 Feb 28. Epub 2017 Feb 28. PMID: 28245338
Article Published Date : Feb 27, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors
[+]

Boswellic acid inhibits growth and metastasis of human colorectal cancer.Apr 30, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Cancer. 2012 May 1 ;130(9):2176-84. Epub 2011 Sep 12. PMID: 21702037
Article Published Date : Apr 30, 2012
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Cancer Metastasis, Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anti-metastatic, Antiproliferative , Cyclooxygenase 2 Inhibitors, Enzyme Inhibitors
[+]

Effects of Boswellia serrata resin extract on motor dysfunction and brain oxidative stress in an experimental model of Parkinson's disease.Apr 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2019 May-Jun;9(3):281-290. PMID: 31143695
Article Published Date : Apr 30, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Brain: Oxidative Stress, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Extracts of Boswellia serrata protect against focal cerebral ischemia and reperfusion injury in rats.Aug 11, 2016

Pubmed Data : Phytother Res. 2016 Aug 12. Epub 2016 Aug 12. PMID: 27515127
Article Published Date : Aug 11, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Frankincense and Myrrh suppressed arthritic progression in rats more effective than single drug treatment. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:13668. Epub 2015 Sep 2. PMID: 26329643
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Frankincense, Myrrh
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Frankincense essential oil from Boswellia sacra is capable of suppressing viability and inducing apoptosis in pancreatic cancer cell lines.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 ;12:253. Epub 2012 Dec 13. PMID: 23237355
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Frankincense has promising potential to modulate not only inflammation, oxidative stress but also immune dysregulation.Dec 31, 2016

Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:7468064. Epub 2017 Mar 13. PMID: 28386311
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Frankincense upregulates the hippocampal calcium/calmodulin kinase II-α during development of the rat brain and improves memory performance.Sep 30, 2018

Pubmed Data : Int J Dev Neurosci. 2018 Oct ;69:44-48. Epub 2018 Jun 30. PMID: 29966740
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Frankincense, pine needle and geranium essential oils suppress breast tumor progression.Dec 31, 2017

Pubmed Data : Oncol Rep. 2018 Jan ;39(1):129-137. Epub 2017 Nov 1. PMID: 29115548
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense, Geranium, Pine Needle
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Essential Oils
[+]

Polyphenol-rich Boswellia serrata gum prevents cognitive impairment and insulin resistance of diabetic rats. Nov 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Nov 2 ;109:281-292. Epub 2018 Nov 2. PMID: 30396086
Article Published Date : Nov 01, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Alzheimer's Disease, Diabetes: Cognitive Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Pre-treatment with Boswellia gum resin tablets decreased the severity of inflammation and number of bleeding spots among ulcer-induced rabbits.Mar 31, 2016

Pubmed Data : AAPS PharmSciTech. 2016 Apr ;17(2):328-38. Epub 2015 Jun 20. PMID: 26092303
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Gastric Ulcer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Pre-treatment with β-Boswellic acid improves blood stasis induced endothelial dysfunction.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:15357. Epub 2015 Oct 20. PMID: 26482008
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Endothelial Dysfunction
[+]

The combination of Boswellia serrate and Melissa officinalis extracts had the ability to improve memory as its traditional use.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Psychiatry Behav Sci. 2016 Sep ;10(3):e681. Epub 2016 Aug 15. PMID: 27822272
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense, Lemon Balm
Diseases : Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

These findings support that boswellic acid is a potent hepato-protective agent.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicine (Taipei). 2017 Jun ;7(2):13. Epub 2017 Jun 14. PMID: 28612711
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

These results suggest that the effect of boswellic acid in improving the cognitive function may be mediated through its antioxidant activity.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2017 Mar ;20(1):10-17. PMID: 28392957
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Wound healing potential of the standardized extract of Boswellia serrata on experimental diabetic foot ulcer.Mar 24, 2019

Pubmed Data : Planta Med. 2019 Mar 25. Epub 2019 Mar 25. PMID: 30909313
Article Published Date : Mar 24, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A review of herbal therapy in multiple sclerosis.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2018 Nov ;8(4):575-590. Epub 2018 Nov 29. PMID: 30607330
Article Published Date : Oct 31, 2018
Study Type : Review
Additional Links
Substances : Cannabis, Cranberry, Frankincense, Ginger, Ginkgo biloba, Ginseng, Grape, Kava Kava, Nigella sativa (aka Black Seed), Saffron, St. Johns Wort, Turmeric, Valerian
Diseases : Multiple Sclerosis
[+]

A review of the role of dietary supplements in inflammatory bowel disease.Nov 30, 2016

Pubmed Data : Eur J Gastroenterol Hepatol. 2016 Dec ;28(12):1357-1364. PMID: 27769076
Article Published Date : Nov 30, 2016
Study Type : Review
Additional Links
Substances : Curcumin, Folic Acid , Frankincense, Green Tea, Probiotics, Vitamin B-12, Vitamin D
Diseases : Inflammatory Bowel Diseases
[+]

An anti-inflammatory activity of B. serrata extracts on endothelial cells was reported.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:2504305. Epub 2018 Jun 25. PMID: 30046370
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

B. carteri essential oil vapour and incense fume resulted in significant reduction of air-borne viable microbial counts for fungi and for bacteria.Jun 11, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jun 12 ;219:1-14. Epub 2018 Mar 9. PMID: 29530608
Article Published Date : Jun 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense, Myrrh
Pharmacological Actions : Antimicrobial
Additional Keywords : Air Purifiers, Essential Oils
[+]

B. sernata and AKBA reduce neuronal cell death induced by OGSD and this neuroprotective effect is mediated via attenuation of oxidative stress.Apr 30, 2017

Pubmed Data : Acta Pol Pharm. 2017 May ;74(3):911-920. PMID: 29513961
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Brain Ischemia, DNA damage, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

B. serrata extract inhibits proliferation, angiogenesis and migration and induces apoptosis in HT-29 cellsMay 23, 2017

Pubmed Data : Prostaglandins Other Lipid Mediat. 2017 May 24 ;131:1-8. Epub 2017 May 24. PMID: 28549801
Article Published Date : May 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Colon Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Prostaglandin PGE2 downregulation, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Plant Extracts
[+]

Boswellia extracts inhibited 5-lipoxygenase (5-LO) activity.Feb 29, 2000

Pubmed Data : Planta Med. 2000 Mar ;66(2):110-3. PMID: 10763581
Article Published Date : Feb 29, 2000
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Boswellia frereana suppresses Hepatocyte growth factor-mediated breast cancer cell invasion and migration.Oct 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2018 Oct 12 ;16(1):281. Epub 2018 Oct 12. PMID: 30314527
Article Published Date : Oct 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Boswellia ovalifoliolata abrogates ROS mediated NF-κB activation, causes apoptosis and chemosensitization in triple negative breast cancer cells.Jun 30, 2014

Pubmed Data : Environ Toxicol Pharmacol. 2014 Jul ;38(1):58-70. Epub 2014 May 14. PMID: 24908637
Article Published Date : Jun 30, 2014
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer, Breast Cancer: Triple Negative , Cancers: Drug Resistant
Pharmacological Actions : Apoptotic, Bcl-2 protein down-regulation, Cell cycle arrest, Chemosensitizer, NF-kappaB Inhibitor
Additional Keywords : Chemotherapeutic Synergy: Cisplatin, Chemotherapeutic Synergy: Doxorubicin, Plant Extracts
[+]

Boswellia serrata oleo-gum-resin and β-boswellic acid inhibits HSV-1 infection in vitro.Nov 30, 2018

Pubmed Data : Phytomedicine. 2018 Dec 1 ;51:94-103. Epub 2018 Oct 16. PMID: 30466633
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Herpes Simplex Virus Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, NF-kappaB Inhibitor
[+]

Boswellia serrate protects intestinal epithelial barrier from inflammatory damage and supports its use as safe adjuvant in patients affected by IBD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(5):e0125375. Epub 2015 May 8. PMID: 25955295
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Boswellic acids appear to be promising candidates for anticancer drug development in future.Jun 20, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jun 21. Epub 2016 Jun 21. PMID: 27346540
Article Published Date : Jun 20, 2016
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Cancers: All
Pharmacological Actions : Apoptotic
[+]

Boswellic extracts and 11-keto-ß-boswellic acids prevent type 1 and type 2 diabetes mellitus by suppressing the expression of proinflammatory cytokines.Jun 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2019 Jun 28 ;63:153002. Epub 2019 Jun 28. PMID: 31301539
Article Published Date : Jun 27, 2019
Study Type : Review
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

C. longa and B. serrata resulted to be promising agents for the management of inflammatory bowel diseases.Nov 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2018 Nov 20 ;11(4). Epub 2018 Nov 20. PMID: 30463367
Article Published Date : Nov 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense, Turmeric
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chemical differentiation of Boswellia sacra and Boswellia carterii essential oils.Oct 25, 2012

Pubmed Data : J Chromatogr A. 2012 Oct 26 ;1261:158-63. Epub 2012 Jun 28. PMID: 22835693
Article Published Date : Oct 25, 2012
Study Type : Plant Study
Additional Links
Substances : Frankincense
Additional Keywords : Cultivars, Essential Oils
[+]

Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells.Nov 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2018 Nov 15 ;50:285-299. Epub 2018 Sep 20. PMID: 30466988
Article Published Date : Nov 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Pain, Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Current status of top 10 nutraceuticals used for Knee Osteoarthritis in India.Sep 30, 2018

Pubmed Data : J Clin Orthop Trauma. 2018 Oct-Dec;9(4):338-348. Epub 2018 Jul 20. PMID: 30449982
Article Published Date : Sep 30, 2018
Study Type : Review
Additional Links
Substances : Chondroitin Sulfate, Curcumin, Fish Oil, Frankincense, Ginger, Glucosamine, Green Tea
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

Distribution of the anti-inflammatory and anti-depressant compounds: Incensole and incensole acetate in genus Boswellia.Apr 30, 2019

Pubmed Data : Phytochemistry. 2019 May ;161:28-40. Epub 2019 Feb 22. PMID: 30802641
Article Published Date : Apr 30, 2019
Study Type : Review
Additional Links
Substances : Frankincense
Diseases : Depression, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
[+]

Frankincense protects against glutamate-Induced oxidative stress and apoptosis in PC12 and N2a cells.Aug 04, 2016

Pubmed Data : DNA Cell Biol. 2016 Aug 5. Epub 2016 Aug 5. PMID: 27494534
Article Published Date : Aug 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Natural products for promoting joint health and managing osteoarthritis.Sep 18, 2018

Pubmed Data : Curr Rheumatol Rep. 2018 Sep 19 ;20(11):72. Epub 2018 Sep 19. PMID: 30232562
Article Published Date : Sep 18, 2018
Study Type : Review
Additional Links
Substances : Curcumin, Frankincense, Pycnogenol (Pine Bark)
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Polysaccharides isolated from frankincense have the potential to be used as an immunological stimulant or nutraceutical.Apr 10, 2019

Pubmed Data : Int J Biol Macromol. 2019 Apr 11 ;133:76-85. Epub 2019 Apr 11. PMID: 30981779
Article Published Date : Apr 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Pharmacological Actions : Immunostimulatory
Additional Keywords : Polysaccharides
[+]

Terpenoids from the Boswellia serrata have antiplasmodial effects in vitro.Jul 23, 2017

Pubmed Data : Planta Med. 2017 Jul 24. Epub 2017 Jul 24. PMID: 28738439
Article Published Date : Jul 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Protozoan Infections
Pharmacological Actions : Antiprotozoal Agents
[+]

These findings suggest 3-acetyl-11-keto-β-boswellic acid as a therapeutic drug for alleviating the symptoms of neuroinflammatory disorders.Oct 26, 2017

Pubmed Data : Mol Neurobiol. 2017 Oct 27. Epub 2017 Oct 27. PMID: 29079998
Article Published Date : Oct 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Neuroprotective Agents
[+]

This reviews the favorable results from the use of herbal and plant products in inflammatory bowel disease.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Gastroenterol. 2016 Jul-Sep;29(3):268-81. Epub 2016 Feb 20. PMID: 27366027
Article Published Date : Jun 30, 2016
Study Type : Review
Additional Links
Substances : Aloe Vera, Artemisinin, Curcumin, Frankincense, Green Tea, Lemongrass, Panax Notoginseng, Wormwood
Diseases : Crohn's Disease, Inflammatory Bowel Diseases, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Transcriptomic profiling of MDA-MB-231 cells exposed to Boswellia Serrata.Oct 31, 2017

Pubmed Data : Cancer Genomics Proteomics. 2017 Nov-Dec;14(6):409-425. PMID: 29109091
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

Copyright: huandi / 123RF Stock Photo

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Believe In Boswellia - Reviving Ancient Wisdom
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Frankincense oil may receive most of the fame and glory, but the humble boswellia tree from which it is derived, can also create another powerful natural medicine. Oil and extracts of boswellia have been used for thousands of years to treat numerous health conditions.

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