Frankincense

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34 Diseases Researched for Frankincense
NameACCKFocus
Osteoarthritis: Knee550Locked
Brain Edema220Locked
Pain220Locked
Inflammation416Locked
Breast Cancer215Locked
Oxidative Stress314Locked
Arthritis212Locked
Cancers: All211Locked
Ulcerative Colitis211Locked
Advanced Glycation End products (AGE)110Locked
Aging Skin110Locked
Allergic Rhinitis110Locked
Anxiety Disorders110Locked
Asthma110Locked
Brain Inflammation 110Locked
Depression110Locked
Irritable Bowel Syndrome110Locked
Lipid Peroxidation110Locked
Bladder Cancer15Locked
Cancer Metastasis15Locked
Cognitive Decline/Dysfunction24Locked
Colon Cancer23Locked
Inflammatory Bowel Diseases33Locked
Cerebral Ischemia12Locked
Colon Cancer: Prevention12Locked
Diabetes Mellitus: Type 212Locked
Endothelial Dysfunction12Locked
Gastric Ulcer12Locked
Learning disorders12Locked
Memory Disorders12Locked
Pancreatic Cancer12Locked
Rheumatoid Arthritis12Locked
Crohn's Disease11Locked
Protozoan Infections11Locked
35 Pharmacological Actions Researched for Frankincense
NameACCKFocus
Anti-Inflammatory Agents1592Locked
Analgesics440Locked
Antioxidants626Locked
Apoptotic514Locked
Cyclooxygenase 2 Inhibitors212Locked
Anti-Allergic Agents110Locked
Anti-Asthmatic Agents110Locked
Antinoceceptive 110Locked
Cell cycle arrest210Locked
Chemotherapeutic110Locked
Matrix metalloproteinase-3 (MMP-3) inhibitor110Locked
Photoprotective110Locked
Radioprotective110Locked
Neuroprotective Agents59Locked
Antiproliferative 38Locked
Immunomodulatory13Locked
Anticarcinogenic Agents12Locked
Brain-derived neurotrophic factor modulator12Locked
Chemopreventive12Locked
Gastroprotective12Locked
Gluconeogenesis Inhibitor12Locked
Interferon Gamma Reducer12Locked
Interleukin-1 beta downregulation12Locked
Interleukin-10 downregulation12Locked
Interleukin-12 downregulation12Locked
Interleukin-2 Downregulation12Locked
Tumor Necrosis Factor (TNF) Alpha Inhibitor12Locked
5-Lipoxygenase Inhibitor11Locked
Anti-metastatic11Locked
Antiprotozoal Agents11Locked
Matrix metalloproteinase-2 (MMP-2) inhibitor11Locked
Matrix metalloproteinase-9 (MMP-9) inhibitor11Locked
NF-kappaB Inhibitor11Locked
Prostaglandin PGE2 downregulation11Locked
Vascular Endothelial Growth Factor Inhibitors11Locked

View the Evidence:
71 Abstracts with Frankincense Research

[+]

A Boswellia-based cream could be used for prevention of adjuvant radiotherapy skin damage in mammary carcinoma.Mar 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2015 Apr ;19(8):1338-44. PMID: 25967706
Article Published Date : Mar 31, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer
Pharmacological Actions : Chemotherapeutic, Radioprotective
Additional Keywords : Plant Extracts
[+]

A formulation containing Frankincense and Turmeric extracts demonstrated a greater improvement in the treatment of OA than celecoxib.Oct 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2013 Nov ;8(5):1542-8. Epub 2013 Aug 29. PMID: 24002213
Article Published Date : Oct 31, 2013
Study Type : Human Study
Additional Links
Substances : Frankincense, Turmeric
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
Problem Substances : Celecoxib, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

A Frankincense extract attenuates the symptoms associated with mild Ulcerative Colitis in remission.May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Jun ;20(12):2695-700. PMID: 27383325
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

A herbal formulation is a safe and effective intervention for management of joint discomfort.Apr 30, 2018

Pubmed Data : J Med Food. 2018 May ;21(5):511-520. Epub 2018 Apr 30. PMID: 29708818
Article Published Date : Apr 30, 2018
Study Type : Human Study
Additional Links
Substances : Frankincense, Haritaki (Terminalia chebula), Turmeric
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

A pilot study to examine the effects of an anti-inflammatory supplement on eicosanoid derivatives in patients with chronic kidney disease.Jul 31, 2017

Pubmed Data : J Altern Complement Med. 2017 Aug ;23(8):632-638. Epub 2017 Apr 4. PMID: 28375641
Article Published Date : Jul 31, 2017
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Kidney Disease (CKD), Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Administration of Boswellia serrate extract with a high fat meal boosted boswellic acid levels. Nov 30, 2004

Pubmed Data : Planta Med. 2004 Dec ;70(12):1155-60. PMID: 15643550
Article Published Date : Nov 30, 2004
Study Type : Human Study
Additional Links
Substances : Frankincense
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Aflapin exhibited better efficacy compared to 5-Loxin to reduce pain and improve physical functions significantly in OA subjects.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Med Sci. 2010 ;7(6):366-77. Epub 2010 Nov 1. PMID: 21060724
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Plant Extracts
[+]

Boswellia serrata Extract could be recommended in patients of osteoarthritis of the knee with possible therapeutic use in other arthritis.Dec 31, 2002

Pubmed Data : Phytomedicine. 2003 Jan ;10(1):3-7. PMID: 12622457
Article Published Date : Dec 31, 2002
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Arthritis, Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Boswellia serrata significantly increased the pain threshold and pain tolerance force and time compared to baseline and placebo.Aug 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Indian J Pharmacol. 2014 Sep-Oct;46(5):475-9. PMID: 25298573
Article Published Date : Aug 31, 2014
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Pain
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Plant Extracts
[+]

Boswellia serrata significantly reduced cerebral edema measured by MRI in the study population.Aug 14, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cancer. 2011 Aug 15 ;117(16):3788-95. Epub 2011 Feb 1. PMID: 21287538
Article Published Date : Aug 14, 2011
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Brain Edema, Cancers: All
Therapeutic Actions : Placebo Effect
Additional Keywords : Medication Reduction, Phytotherapy
Problem Substances : Dexamethasone, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Boswellic acids could be used to reduce peritumoral edema associated with primary and secondary brain tumors.Dec 14, 2011

Pubmed Data : J Pharm Biomed Anal. 2011 Dec 15 ;56(5):998-1005. Epub 2011 Jul 29. PMID: 21855244
Article Published Date : Dec 14, 2011
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Brain Edema, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Casperome supplementation could represent a promising alternative approach to manage symptoms associated with IBS.Apr 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2017 May ;21(9):2249-2254. PMID: 28537656
Article Published Date : Apr 30, 2017
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Irritable Bowel Syndrome
[+]

Constitutes of Boswellia serrata extract act synergistically to exert anti-inflammatory/anti-arthritic activity.Mar 05, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytother Res. 2019 Mar 6. Epub 2019 Mar 6. PMID: 30838706
Article Published Date : Mar 05, 2019
Study Type : Human Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Natural Substance Synergy
[+]

Curcumin and Boswellia serrate has beneficial effects on glycoxidation and lipid peroxidation in chronically exercising master athletes.Nov 20, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Nov 21 ;8(11). Epub 2016 Nov 21. PMID: 27879642
Article Published Date : Nov 20, 2016
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Advanced Glycation End products (AGE), Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Antioxidants
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Essential oil hand massage was used with hospice patients with terminal cancer with a positive effect on pain and depression.Jul 31, 2008

Pubmed Data : Taehan Kanho Hakhoe Chi. 2008 Aug ;38(4):493-502. PMID: 18753801
Article Published Date : Jul 31, 2008
Study Type : Human Study
Additional Links
Substances : Bergamot, Frankincense, Lavender
Diseases : Anxiety Disorders, Depression, Pain
Therapeutic Actions : Aromatherapy Massage
[+]

Inhalation of aromatherapy essential oil may have potential as an effective intervention to alleviate perennial allergic rhinitis.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2016 ;2016:7896081. Epub 2016 Mar 13. PMID: 27034695
Article Published Date : Dec 31, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense, Sandalwood
Diseases : Allergic Rhinitis
Therapeutic Actions : Aromatherapy
Pharmacological Actions : Anti-Allergic Agents
Additional Keywords : Essential Oils
[+]

Interference with catG could explain some of the anti-inflammatory properties of frankincense.Aug 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Immunol. 2009 Sep 1 ;183(5):3433-42. Epub 2009 Jul 31. PMID: 19648270
Article Published Date : Aug 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritisFeb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2016 Mar ;29(1):140-6. Epub 2015 Dec 18. PMID: 26684635
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense, MSM (Methylsulfonylmethane)
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors
[+]

Supplementation with Boswellia had beneficial effects on pain, stiffness and physical functions in patients with symptomatic knee osteoarthritis.Nov 30, 2014

Pubmed Data : Minerva Med. 2014 Dec ;105(6 Suppl 2):9-16. PMID: 26076376
Article Published Date : Nov 30, 2014
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

The Boswellia serrate and lemon balm tablet in older adults can be beneficial on improvement of memory.Mar 31, 2018

Pubmed Data : Arch Gerontol Geriatr. 2018 Mar - Apr;75:146-150. Epub 2017 Dec 28. PMID: 29306113
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Substances : Frankincense, Lemon Balm
Diseases : Cognitive Decline/Dysfunction, Memory Disorders
Pharmacological Actions : Neuroprotective Agents
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The use of Boswellia phytosome extracts are beneficial for asthmatic patients as it helps reduce the need for inhalation therapy.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2015 Oct ;19(19):3757-62. PMID: 26502867
Article Published Date : Sep 30, 2015
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Asthma
Pharmacological Actions : Anti-Asthmatic Agents
[+]

These preliminary results indicate the efficacy and safety of Movardol supplementation in the management of moderate knee osteoarthritis.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Eur Rev Med Pharmacol Sci. 2016 Dec ;20(24):5198-5204. PMID: 28051248
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Substances : Frankincense, Ginger
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Topical application of boswellic acids may represent a suitable treatment option for selected features of skin photoaging.Dec 31, 2009

Pubmed Data : Dermatol Ther. 2010 Jan-Feb;23 Suppl 1:S28-32. PMID: 20136919
Article Published Date : Dec 31, 2009
Study Type : Human Study
Additional Links
Substances : Frankincense
Diseases : Aging Skin
Pharmacological Actions : Photoprotective
Additional Keywords : Plant Extracts
[+]

Twelve-week use of curcumin complex or its combination with boswellic acid reduces pain-related symptoms in patients with osteoarthritis.Jan 08, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2018 Jan 9 ;18(1):7. Epub 2018 Jan 9. PMID: 29316908
Article Published Date : Jan 08, 2018
Study Type : Human Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Osteoarthritis
Pharmacological Actions : Analgesics
Additional Keywords : Natural Substance Synergy
[+]

Human bladder cancer cells and immortalized normal bladder cells were studied using Frankincense oil; Frankincense oil appears to distinguish cancerous from normal bladder cells and suppress cancer cell viability. Dec 31, 2008

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2009 ;9:6. Epub 2009 Mar 18. PMID: 19296830
Article Published Date : Dec 31, 2008
Study Type : Human In Vitro
Additional Links
Substances : Frankincense
Diseases : Bladder Cancer
Pharmacological Actions : Apoptotic, Cell cycle arrest
Additional Keywords : Plant Extracts, Selective Cytotoxicity
[+]

This study compares Boswellia sacra essential oil hydrodistilled at 100 °C vs 78 °C in inducing cancer cell death in cultured breast cancer cells; the oil prepared at 100 °C was more potent in inducing breast cancer cell-specific cytotoxicity.Dec 31, 2010

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2011 ;11:129. Epub 2011 Dec 15. PMID: 22171782
Article Published Date : Dec 31, 2010
Study Type : Human In Vitro
Additional Links
Substances : Frankincense
Diseases : Breast Cancer, Cancer Metastasis
Pharmacological Actions : Antiproliferative , Apoptotic, Cell cycle arrest
Additional Keywords : Selective Cytotoxicity
[+]

This article describes one patient's experience using frankincense (Boswellia carterii) essential oil to help in the management of her fatigue.Dec 31, 2017

Pubmed Data : Holist Nurs Pract. 2018 May/Jun;32(3):140-142. PMID: 29642127
Article Published Date : Dec 31, 2017
Study Type : Human: Case Report
Additional Links
Substances : Frankincense
Diseases : Cancer: Fatigue
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A plant mixture comprising Nigella sativa, Myrrh, Gum Olibanum (Frankincense), Gum Asafoetida and Aloe lowers blood sugar by inhibiting hepatis gluconeogenesis. Dec 01, 1991

Pubmed Data : Diabetes Res. 1991 Dec;18(4):163-8. PMID: 1842751
Article Published Date : Dec 01, 1991
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Asafoetida, Frankincense, Myrrh, Nigella sativa (aka Black Seed)
Diseases : Diabetes Mellitus: Type 2
Pharmacological Actions : Gluconeogenesis Inhibitor
Additional Keywords : Plant Extracts
[+]

Acetyl-11-keto-β-boswellic acid extracted from Boswellia serrata promotes Schwann cell proliferation and sciatic nerve function recovery.Feb 28, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Neural Regen Res. 2018 Mar ;13(3):484-491. PMID: 29623934
Article Published Date : Feb 28, 2018
Study Type : Animal Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Pharmacological Actions : Regenerative
Additional Keywords : Nerve Regeneration
[+]

Administration of Boswellia resin in aged Wistar ratd was able to improve learning capability.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Avicenna J Phytomed. 2016 Mar-Apr;6(2):189-97. PMID: 27222832
Article Published Date : Feb 29, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Anti-inflammatory and anti-arthritic effects of methanol extract of the stem bark of Boswellia dalzielii.Nov 30, 2018

Pubmed Data : Inflammopharmacology. 2018 Dec ;26(6):1383-1398. Epub 2018 Jun 13. PMID: 29948494
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Boswellia sacra and folic acid attenuated the neurodegenerative effects of EMF in the hippocampus and cerebellum.Sep 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Microsc Ultrastruct. 2017 Oct-Dec;5(4):216-224. Epub 2017 Sep 18. PMID: 30023257
Article Published Date : Sep 30, 2017
Study Type : Animal Study
Additional Links
Substances : Folic Acid , Frankincense
Diseases : Mobile Phone-Induced Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents, Radioprotective
Anti Therapeutic Actions : Mobile Phone Radiation
[+]

Boswellia serrata gum resin aqueous extract upregulates BDNF.Nov 16, 2016

Pubmed Data : Turk J Med Sci. 2016 Nov 17 ;46(5):1573-1578. Epub 2016 Nov 17. PMID: 27966331
Article Published Date : Nov 16, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Learning disorders
Pharmacological Actions : Brain-derived neurotrophic factor modulator
[+]

Boswellia serrate extract has great potential to suppress colon tumorigenesis.Feb 27, 2017

Pubmed Data : Mol Nutr Food Res. 2017 Feb 28. Epub 2017 Feb 28. PMID: 28245338
Article Published Date : Feb 27, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Colon Cancer, Colon Cancer: Prevention
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors
[+]

Extracts of Boswellia serrata protect against focal cerebral ischemia and reperfusion injury in rats.Aug 11, 2016

Pubmed Data : Phytother Res. 2016 Aug 12. Epub 2016 Aug 12. PMID: 27515127
Article Published Date : Aug 11, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cerebral Ischemia
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Frankincense and Myrrh suppressed arthritic progression in rats more effective than single drug treatment. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:13668. Epub 2015 Sep 2. PMID: 26329643
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Frankincense, Myrrh
Diseases : Arthritis, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Frankincense essential oil from Boswellia sacra is capable of suppressing viability and inducing apoptosis in pancreatic cancer cell lines.Dec 31, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2012 ;12:253. Epub 2012 Dec 13. PMID: 23237355
Article Published Date : Dec 31, 2011
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Pancreatic Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Plant Extracts
[+]

Frankincense has promising potential to modulate not only inflammation, oxidative stress but also immune dysregulation.Dec 31, 2016

Pubmed Data : Oxid Med Cell Longev. 2017 ;2017:7468064. Epub 2017 Mar 13. PMID: 28386311
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory
Additional Keywords : Plant Extracts
[+]

Frankincense upregulates the hippocampal calcium/calmodulin kinase II-α during development of the rat brain and improves memory performance.Sep 30, 2018

Pubmed Data : Int J Dev Neurosci. 2018 Oct ;69:44-48. Epub 2018 Jun 30. PMID: 29966740
Article Published Date : Sep 30, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Memory Disorders
Pharmacological Actions : Neuroprotective Agents
Additional Keywords : Plant Extracts
[+]

Frankincense, pine needle and geranium essential oils suppress breast tumor progression.Dec 31, 2017

Pubmed Data : Oncol Rep. 2018 Jan ;39(1):129-137. Epub 2017 Nov 1. PMID: 29115548
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Frankincense, Geranium, Pine Needle
Diseases : Breast Cancer
Pharmacological Actions : Antiproliferative , Apoptotic
Additional Keywords : Essential Oils
[+]

Polyphenol-rich Boswellia serrata gum prevents cognitive impairment and insulin resistance of diabetic rats. Nov 01, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2018 Nov 2 ;109:281-292. Epub 2018 Nov 2. PMID: 30396086
Article Published Date : Nov 01, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Alzheimer's Disease, Diabetes: Cognitive Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Neuroprotective Agents
[+]

Pre-treatment with Boswellia gum resin tablets decreased the severity of inflammation and number of bleeding spots among ulcer-induced rabbits.Mar 31, 2016

Pubmed Data : AAPS PharmSciTech. 2016 Apr ;17(2):328-38. Epub 2015 Jun 20. PMID: 26092303
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Gastric Ulcer, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective
Problem Substances : Indomethacin
[+]

Pre-treatment with β-Boswellic acid improves blood stasis induced endothelial dysfunction.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2015 ;5:15357. Epub 2015 Oct 20. PMID: 26482008
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Endothelial Dysfunction
[+]

The combination of Boswellia serrate and Melissa officinalis extracts had the ability to improve memory as its traditional use.Aug 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Iran J Psychiatry Behav Sci. 2016 Sep ;10(3):e681. Epub 2016 Aug 15. PMID: 27822272
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Frankincense, Lemon Balm
Diseases : Memory Disorders
Pharmacological Actions : Neuroprotective Agents
[+]

These findings support that boswellic acid is a potent hepato-protective agent.May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomedicine (Taipei). 2017 Jun ;7(2):13. Epub 2017 Jun 14. PMID: 28612711
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective
Problem Substances : Acetaminophen, Paracetamol
[+]

These results suggest that the effect of boswellic acid in improving the cognitive function may be mediated through its antioxidant activity.Feb 28, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pharmacopuncture. 2017 Mar ;20(1):10-17. PMID: 28392957
Article Published Date : Feb 28, 2017
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Cognitive Decline/Dysfunction
Pharmacological Actions : Neuroprotective Agents
[+]

Wound healing potential of the standardized extract of Boswellia serrata on experimental diabetic foot ulcer.Mar 24, 2019

Pubmed Data : Planta Med. 2019 Mar 25. Epub 2019 Mar 25. PMID: 30909313
Article Published Date : Mar 24, 2019
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Diabetic Ulcer, Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents
[+]

A review of herbal therapy in multiple sclerosis.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Pharm Bull. 2018 Nov ;8(4):575-590. Epub 2018 Nov 29. PMID: 30607330
Article Published Date : Oct 31, 2018
Study Type : Review
Additional Links
Substances : Cannabis, Cranberry, Frankincense, Ginger, Ginkgo biloba, Ginseng, Grape, Kava Kava, Nigella sativa (aka Black Seed), Saffron, St. Johns Wort, Turmeric, Valerian
Diseases : Multiple Sclerosis
[+]

A review of the role of dietary supplements in inflammatory bowel disease.Nov 30, 2016

Pubmed Data : Eur J Gastroenterol Hepatol. 2016 Dec ;28(12):1357-1364. PMID: 27769076
Article Published Date : Nov 30, 2016
Study Type : Review
Additional Links
Substances : Curcumin, Folic Acid , Frankincense, Green Tea, Probiotics, Vitamin B-12, Vitamin D
Diseases : Inflammatory Bowel Diseases
[+]

An anti-inflammatory activity of B. serrata extracts on endothelial cells was reported.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2018 ;2018:2504305. Epub 2018 Jun 25. PMID: 30046370
Article Published Date : Dec 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

B. carteri essential oil vapour and incense fume resulted in significant reduction of air-borne viable microbial counts for fungi and for bacteria.Jun 11, 2018

Pubmed Data : J Ethnopharmacol. 2018 Jun 12 ;219:1-14. Epub 2018 Mar 9. PMID: 29530608
Article Published Date : Jun 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense, Myrrh
Pharmacological Actions : Antimicrobial
Additional Keywords : Air Purifiers, Essential Oils
[+]

B. sernata and AKBA reduce neuronal cell death induced by OGSD and this neuroprotective effect is mediated via attenuation of oxidative stress.Apr 30, 2017

Pubmed Data : Acta Pol Pharm. 2017 May ;74(3):911-920. PMID: 29513961
Article Published Date : Apr 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Brain Ischemia, DNA damage, Lipid Peroxidation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Antioxidants, Neuroprotective Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

B. serrata extract inhibits proliferation, angiogenesis and migration and induces apoptosis in HT-29 cellsMay 23, 2017

Pubmed Data : Prostaglandins Other Lipid Mediat. 2017 May 24 ;131:1-8. Epub 2017 May 24. PMID: 28549801
Article Published Date : May 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Colon Cancer
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9) inhibitor, Prostaglandin PGE2 downregulation, Vascular Endothelial Growth Factor Inhibitors
Additional Keywords : Plant Extracts
[+]

Boswellia extracts inhibited 5-lipoxygenase (5-LO) activity.Feb 29, 2000

Pubmed Data : Planta Med. 2000 Mar ;66(2):110-3. PMID: 10763581
Article Published Date : Feb 29, 2000
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammation
Pharmacological Actions : 5-Lipoxygenase Inhibitor, Anti-Inflammatory Agents
Additional Keywords : Plant Extracts
[+]

Boswellia frereana suppresses Hepatocyte growth factor-mediated breast cancer cell invasion and migration.Oct 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Transl Med. 2018 Oct 12 ;16(1):281. Epub 2018 Oct 12. PMID: 30314527
Article Published Date : Oct 11, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Antiproliferative
[+]

Boswellia serrata oleo-gum-resin and β-boswellic acid inhibits HSV-1 infection in vitro.Nov 30, 2018

Pubmed Data : Phytomedicine. 2018 Dec 1 ;51:94-103. Epub 2018 Oct 16. PMID: 30466633
Article Published Date : Nov 30, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Herpes Simplex Virus Type 1
Pharmacological Actions : Anti-Inflammatory Agents, Antiviral Agents, NF-kappaB Inhibitor
[+]

Boswellia serrate protects intestinal epithelial barrier from inflammatory damage and supports its use as safe adjuvant in patients affected by IBD.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(5):e0125375. Epub 2015 May 8. PMID: 25955295
Article Published Date : Dec 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Boswellic acids appear to be promising candidates for anticancer drug development in future.Jun 20, 2016

Pubmed Data : J Ethnopharmacol. 2016 Jun 21. Epub 2016 Jun 21. PMID: 27346540
Article Published Date : Jun 20, 2016
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Cancers: All
Pharmacological Actions : Apoptotic
[+]

Boswellic extracts and 11-keto-ß-boswellic acids prevent type 1 and type 2 diabetes mellitus by suppressing the expression of proinflammatory cytokines.Jun 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2019 Jun 28 ;63:153002. Epub 2019 Jun 28. PMID: 31301539
Article Published Date : Jun 27, 2019
Study Type : Review
Additional Links
Substances : acetyl-11-keto-beta-boswellic acid, Frankincense
Diseases : Diabetes Mellitus: Type 1, Diabetes Mellitus: Type 2
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

C. longa and B. serrata resulted to be promising agents for the management of inflammatory bowel diseases.Nov 19, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmaceuticals (Basel). 2018 Nov 20 ;11(4). Epub 2018 Nov 20. PMID: 30463367
Article Published Date : Nov 19, 2018
Study Type : In Vitro Study
Additional Links
Substances : Frankincense, Turmeric
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chemical differentiation of Boswellia sacra and Boswellia carterii essential oils.Oct 25, 2012

Pubmed Data : J Chromatogr A. 2012 Oct 26 ;1261:158-63. Epub 2012 Jun 28. PMID: 22835693
Article Published Date : Oct 25, 2012
Study Type : Plant Study
Additional Links
Substances : Frankincense
Additional Keywords : Cultivars, Essential Oils
[+]

Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells.Nov 14, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Phytomedicine. 2018 Nov 15 ;50:285-299. Epub 2018 Sep 20. PMID: 30466988
Article Published Date : Nov 14, 2018
Study Type : In Vitro Study
Additional Links
Substances : Curcumin, Frankincense
Diseases : Chronic Pain, Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Antinoceceptive
Additional Keywords : Natural Substance Synergy, Plant Extracts
[+]

Current status of top 10 nutraceuticals used for Knee Osteoarthritis in India.Sep 30, 2018

Pubmed Data : J Clin Orthop Trauma. 2018 Oct-Dec;9(4):338-348. Epub 2018 Jul 20. PMID: 30449982
Article Published Date : Sep 30, 2018
Study Type : Review
Additional Links
Substances : Chondroitin Sulfate, Curcumin, Fish Oil, Frankincense, Ginger, Glucosamine, Green Tea
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Osteoprotective
[+]

Distribution of the anti-inflammatory and anti-depressant compounds: Incensole and incensole acetate in genus Boswellia.Apr 30, 2019

Pubmed Data : Phytochemistry. 2019 May ;161:28-40. Epub 2019 Feb 22. PMID: 30802641
Article Published Date : Apr 30, 2019
Study Type : Review
Additional Links
Substances : Frankincense
Diseases : Depression, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents
[+]

Frankincense protects against glutamate-Induced oxidative stress and apoptosis in PC12 and N2a cells.Aug 04, 2016

Pubmed Data : DNA Cell Biol. 2016 Aug 5. Epub 2016 Aug 5. PMID: 27494534
Article Published Date : Aug 04, 2016
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Oxidative Stress
Pharmacological Actions : Antioxidants, Neuroprotective Agents
[+]

Natural products for promoting joint health and managing osteoarthritis.Sep 18, 2018

Pubmed Data : Curr Rheumatol Rep. 2018 Sep 19 ;20(11):72. Epub 2018 Sep 19. PMID: 30232562
Article Published Date : Sep 18, 2018
Study Type : Review
Additional Links
Substances : Curcumin, Frankincense, Pycnogenol (Pine Bark)
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
[+]

Polysaccharides isolated from frankincense have the potential to be used as an immunological stimulant or nutraceutical.Apr 10, 2019

Pubmed Data : Int J Biol Macromol. 2019 Apr 11 ;133:76-85. Epub 2019 Apr 11. PMID: 30981779
Article Published Date : Apr 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Pharmacological Actions : Immunostimulatory
Additional Keywords : Polysaccharides
[+]

Terpenoids from the Boswellia serrata have antiplasmodial effects in vitro.Jul 23, 2017

Pubmed Data : Planta Med. 2017 Jul 24. Epub 2017 Jul 24. PMID: 28738439
Article Published Date : Jul 23, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Protozoan Infections
Pharmacological Actions : Antiprotozoal Agents
[+]

These findings suggest 3-acetyl-11-keto-β-boswellic acid as a therapeutic drug for alleviating the symptoms of neuroinflammatory disorders.Oct 26, 2017

Pubmed Data : Mol Neurobiol. 2017 Oct 27. Epub 2017 Oct 27. PMID: 29079998
Article Published Date : Oct 26, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Brain Inflammation , Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, MicroRNA modulator, Neuroprotective Agents
[+]

This reviews the favorable results from the use of herbal and plant products in inflammatory bowel disease.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ann Gastroenterol. 2016 Jul-Sep;29(3):268-81. Epub 2016 Feb 20. PMID: 27366027
Article Published Date : Jun 30, 2016
Study Type : Review
Additional Links
Substances : Aloe Vera, Artemisinin, Curcumin, Frankincense, Green Tea, Lemongrass, Panax Notoginseng, Wormwood
Diseases : Crohn's Disease, Inflammatory Bowel Diseases, Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants
Additional Keywords : Plant Extracts
[+]

Transcriptomic profiling of MDA-MB-231 cells exposed to Boswellia Serrata.Oct 31, 2017

Pubmed Data : Cancer Genomics Proteomics. 2017 Nov-Dec;14(6):409-425. PMID: 29109091
Article Published Date : Oct 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Frankincense
Diseases : Breast Cancer: Triple Negative
Pharmacological Actions : Anti-metastatic, Antiproliferative , Apoptotic

Copyright: huandi / 123RF Stock Photo

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