Tumor Necrosis Factor TNF Alpha Inhibitor

Name	AC	CK
Curcumin	146	307
Coenzyme Q10	17	116
Omega-3 Fatty Acids	13	92
Ginsenosides	52	85
Resveratrol	42	85
Probiotics	14	78
Vitamin C	20	72
Berberine	27	62
Melatonin	15	57
Fish Oil	6	54
DHA (Docosahexaenoic Acid)	6	53
Polyphenols	26	53
Ginger	25	52
Puerarin	20	50
Vitamin D	11	50
Flavonoids	22	46
Genistein	8	45
Astaxanthin	15	42
Thymoquinone	21	40
Garlic	6	37
Flaxseed	6	36
Lactobacillus casei	6	36
Lactobacillus fermentum	5	34
Quercetin	15	34
Cannabidiol	15	32
Hesperidin	17	31
EGCG (Epigallocatechin gallate)	16	30
Paeoniflorin	17	30
Red Sage	11	28
Garlic: Aged	4	27
Green Tea	10	27
Tanshinone IIA	16	27
Alpha-Lipoic Acid	4	26
Dandelion	16	26
Echinacea	4	26
Astragaloside	14	25
Zinc	5	25
EPA (Eicosapentaenoic Acid)	3	24
Lactobacillus plantarum	9	24
Sulforaphane	15	24
Asiatic Acid	14	23
Fisetin	11	23
Astragalus	3	22
Naringenin	13	22
Wormwood	3	21
Bacillus coagulans	2	20
Breast Milk	2	20
Chokeberry	7	20
Ginkgo biloba	6	20
Lactobacillus Acidophilus	2	20
Mangiferin	11	20
Purslane	11	20
Soup	2	20
Vitamin A	2	20
Cannabis	7	19
Rose	12	19
Fucoidan	10	18
Magnolol	10	18
Parthenolide	8	18
Turmeric	12	18
Lactobacillus rhamnosus GG	5	17
Lychee	7	17
Panax Notoginseng	9	17
Rutin	7	17
Apigenin	11	16
Honey	5	16
Honokiol	8	16
Isoflavones	4	16
Magnesium	4	16
Nigella sativa (aka Black Seed)	4	16
Nobiletin	10	16
Oleuropein	7	16
Pomegranate	8	16
Sesamol	9	16
Silibinin	5	16
Fermented Foods and Beverages	4	15
Lactobacillus reuteri	4	15
Lotus	8	15
Luteolin	8	15
NAC (N-acetyl-L-cysteine)	4	15
Tart Cherry	4	15
Caffeic acid phenethyl ester	3	14
Camel Milk	7	14
Diosmin	8	14
Ellagic Acid	8	14
Gingerol	8	14
Kefir	7	14
Lactobacillus paracasei	3	14
Olive	3	14
Spirulina	7	14
Anthocyanins	7	13
Bee Venom	6	13
Cat's Claw	4	13
Chrysin	8	13
Ginseng (Korean)	7	13
Pterostilbene	7	13
Rice Bran	3	13
Ashwagandha	8	12
Baicalein	7	12
Bilberry	2	12
Citrus naringin	6	12
Hydrogen Water	6	12
Isoliquiritigenin	7	12
Lactobacillus probiotics	2	12
Palmitoylethanolamide	6	12
Pumpkin Seeds	2	12
Punicalagin	5	12
Sesame Seeds	2	12
Vitamin E: alpha tocopherol	2	12
Acai	4	11
Black Raspberry	2	11
Blueberry	7	11
Cannabinoids	7	11
Chrysanthemum Indicum	7	11
D-Limonene	2	11
Fruit: All	2	11
Fucoxanthin	6	11
Glutathione	2	11
Huperzine	6	11
Progesterone	2	11
Sea buckthorn	6	11
Vegetables: All	2	11
Aloe Vera	6	10
Bifidobacterium Bifidum	1	10
Bloodroot	1	10
Chocolate	1	10
DHEA (Dehydroepiandrosterone)	1	10
Eicosapentaenoic acid (EPA)	1	10
Folic Acid	1	10
Gamma-Linoleic Acid (GLA)	1	10
Gastrodin	6	10
Indole-3-Carbinol	5	10
Kaempferol	6	10
Lactobacillus delbrueckii Subsp	1	10
Mastic gum	1	10
Moringa oleifera	6	10
Olive leaf extract	6	10
Omega-6 Fatty Acids	1	10
Peanut	1	10
Psyllium	1	10
Reishi Mushroom	5	10
Selenium	6	10
Sesamin	1	10
Soy Protein	1	10
Stilbenes	6	10
TA-65 (Astragalus compound)	1	10
Tangeretin	6	10
Tryptophan	1	10
Vitamin B-12	1	10
Vitexins	4	10
Wine	1	10
Yerba Mate	1	10
Allicin	6	9
Bamboo	3	9
Betulinic acid	5	9
Chinese Skullcap	5	9
Genipin	5	9
Geraniol	5	9
Myricetin	5	9
P-Coumaric Acid	5	9
Rosemaric Acid	5	9
Shikonin	5	9
Thymol	5	9
Agaricus Blazei	4	8
Bifidobacterium Longum	4	8
Chaga Mushroom (Inonotus obliquus)	4	8
Chlorogenic Acid	4	8
Crocin	4	8
Diosgenin	4	8
Ferulic acid	4	8
Gotu Kola	5	8
Grape Seed Extract	4	8
Ligustrazine	4	8
Lion's Mane (Hericium Erinaceus)	5	8
Lycopene	5	8
Phloretin	5	8
Piperine	5	8
Rosemary	6	8
Sweet Potato: Purple	5	8
Apple Polyphenols	4	7
Arginine	4	7
Gallic Acid	4	7
Japanese cypress	4	7
Milk Thistle	4	7
Nettle	4	7
Olive Oil	2	7
Piceatannol	5	7
Rosmarinic acid	2	7
Adlay	5	6
Amygdalin	3	6
Bacopa	4	6
Burdock	4	6
Carnosic Acid	4	6
Citrus Peel	3	6
Cranberry	3	6
Eucalyptus	3	6
Ginseng	3	6
Grape	3	6
Guduchi	4	6
Histidine	3	6
Hydroxytyrosol	4	6
Lupeol	3	6
MSM (Methylsulfonylmethane)	3	6
Mussel: Green-lipped (Perna canaliculus)	3	6
Orange	3	6
Patchouli	3	6
Propolis: Bee	3	6
Rooibos	3	6
Royal Jelly	5	6
Saffron	4	6
Soy	3	6
St. Johns Wort	3	6
Verbascoside	4	6
Zerumbone	4	6
Beta-Caryophyllene	3	5
Beta-Elemene	3	5
Chamomile	3	5
Citral	1	5
Cocoa	3	5
Delta-tetrahydrocannabinol (THC)	4	5
Diallyl sulfide	3	5
Emodin	3	5
Evening Primrose Oil	3	5
Frankincense	3	5
Goji	3	5
Hops	3	5
Jujube	3	5
Lactobacillus rhamnosus	3	5
Loquat Leaves	3	5
Manuka Honey	3	5
6-Shogaol	2	4
ALA (Alpha-Linolenic Acid)	2	4
Amla Fruit	2	4
Anemarrhena asphodeloides	2	4
Arctigenin	2	4
Artesunate	2	4
Bee Propolis	2	4
Beta-glucan	2	4
Bitter Apple	2	4
Bitter Melon	2	4
Bitter Orange	3	4
Blackberry	2	4
Brown Rice: Pre-Germinated	2	4
Buckwheat	2	4
Cannabinoids: Synthetic	2	4
Carnosine	2	4
Cinnamaldehyde	3	4
Curcuminoids	2	4
Elderberry	2	4
Guava	3	4
Hibiscus sabdariffa	2	4
Hu Zhang (Polygonum cuspidatum)	2	4
Lactobacillus Brevis	2	4
Lactobacillus salivarius	2	4
Lavender: Essential Oil	2	4
Lignans	2	4
Loquat	2	4
Medium Chain Triglycerides	2	4
Mulberry	2	4
Neem	2	4
Palm Oil	2	4
Perillaldehyde	2	4
Persimmon	3	4
Plantago	2	4
Pomegranate Peel	2	4
Potato	2	4
Prunella vulgaris	3	4
Pycnogenol (Pine Bark)	2	4
Rice	2	4
Rubia Cordifolia	2	4
Sage	2	4
Salvia miltiorrhiza	2	4
Saturated fatty acids	2	4
Sembung Leaf	2	4
Silymarin	2	4
Tetrahydrocurcumin	2	4
Theanine	2	4
Vanillin	3	4
Wogonin	3	4
Xanthohumol	3	4
Yellow Tea	2	4
18β-Glycyrrhetinic Acid	2	3
Aduki bean	2	3
Antrodia camphorata	2	3
Ayurvedic formulation: Liv52	2	3
Bael	2	3
Barberry	2	3
Bisdemethoxycurcumin	2	3
Catechin	2	3
Combretum fragrans	2	3
Corn: Purple	2	3
Cucurbitacin B	2	3
Endocannabinoids	2	3
False Black Pepper	2	3
Garcinia Mangostana	2	3
Ginseng (Siberian)	2	3
Hemp Seed	2	3
Horsetail	2	3
Isothiocyanates	2	3
Krill	2	3
Oak	2	3
Oregano	2	3
Perilla	2	3
Plantago asiatica	2	3
Procyanidin B2	2	3
Purple Carrots	2	3
Soybean: Black	2	3
Thyme	2	3
Tomato	2	3
Urolithin A	2	3
Vitex negundo	2	3
Zataria multiflora	2	3
2-Methoxyestradiol	1	2
Alpha Linolenic Acid	1	2
Angelica	1	2
Apocynin	1	2
Apples	1	2
Artemisinin	2	2
Aspen	1	2
Bai Zhu	1	2
Banaba	1	2
Banana	1	2
Barley	1	2
Basil	1	2
Billygoat Weed	1	2
Black Currant	1	2
Black Tea	2	2
Blue Honeysuckle	1	2
Boron	1	2
Bran	1	2
Bromelain	2	2
Butyrate	1	2
Caffeic Acid	1	2
Camu Camu	1	2
Carnitine	1	2
Celadrin	1	2
Chaenomeles speciosa	1	2
Chia	1	2
Chlorella (Algae)	2	2
Chrysanthemum Morifolium	1	2
Citrulline	1	2
Clove	1	2
Coconut Oil	1	2
Coptis chinensis	1	2
Crocetin	1	2
Cryptoxanthin	1	2
Cucurbitacin E	2	2
Curcumin: Degradiation byproducts	1	2
Cyanidin 3-glucoside	1	2
Cysteine (see N-Acetylcysteine)	1	2
Cystine	1	2
Daidzein	1	2
Dihydrocurcumin	1	2
Elm tree	1	2
FOS (Fructooligosaccharides)	1	2
Fiber	1	2
Flavan-3-ols	1	2
Flaxseed Oil	1	2
Garden Cress (Lepidium sativum)	1	2
Gardenia	1	2
Ginseng (American)	1	2
Glutamine	1	2
Glycine	1	2
Glycyrrhizin	1	2
Goldenrod	1	2
Grains: All	1	2
Gymnema Sylvestre	1	2
Hawthorn	1	2
Helenalin	1	2
Holy Basil	1	2
Isoquercitrin	1	2
Kaempferia parviflora	1	2
Kava Kava	2	2
L-Carnitine	1	2
Lemon Balm	1	2
Lemon Verbena	1	2
Licorice	1	2
Ligusticum wallichii	1	2
Litchi	1	2
Magnolia	2	2
Maitake Mushroom	1	2
Mango	1	2
Mangosteen	1	2
Marigold	1	2
Melia azedarach	1	2
Milk: Fermented	1	2
Mint	1	2
Mucuna pruriens (aka Velvet Beans)	1	2
Myrrh	1	2
Natto	1	2
Noni	1	2
Nordihydroguaiaretic acid (NDGA)	1	2
Oats	1	2
Okra	1	2
Onion	1	2
Oyster Mushroom: Indian	1	2
Passion Flower	1	2
Passion fruit	1	2
Pectin	1	2
Pelargonium sidoides	1	2
Peony	1	2
Phyllanthus emblica	1	2
Phytosterols	1	2
Piper cubeba (Cubeb)	1	2
Pipsisssewa	1	2
Plum	1	2
Pomegranate Seed	1	2
Potato: Pigmented	1	2
Propolis: Brazillian	1	2
Psychedelics:All	1	2
Pterocarpus marsupium	1	2
Pulsatilla pratensis	1	2
Punicic acid	2	2
Radish	1	2
Raspberry ketone	1	2
Red Yeast Rice	1	2
Saccharomyces Boulardii	1	2
Seaweed	1	2
Seaweed: Brown	2	2
Shiitake Mushroom	1	2
Sinomenine	1	2
Sour Cherry	2	2
Spikenard	2	2
Stevia	1	2
Stigmasterol	1	2
Strawberry	1	2
Suma (Pfaffia Paniculata)	1	2
Tannic Acid	1	2
Taurine	1	2
Theophylline	1	2
Thioproline	1	2
Thistle	2	2
Thuja	1	2
Toona sinensis	2	2
Tricin	1	2
Triphala	1	2
Tripterygium wilfordii	2	2
Triptolide	2	2
Velvet antler	1	2
Vitamin B-3 (Niacin)	1	2
Vitamin E	1	2
Wheat Bran	1	2
Wheat Grass	1	2
Whey	1	2
White Tea	1	2
Willow Bark	2	2
Yeast	1	2
Zeaxanthin	1	2
4-Shogaol	1	1
Acacia catechu	1	1
Achillea fragrantissima	1	1
Agrimony	1	1
Amygdalin (laetrile)	1	1
Andrographis	1	1
Andrographolide	1	1
Apple Cider Vinegar	1	1
Apple Pectin	1	1
Avocado	1	1
Ayahuasca	1	1
Barley Grass	1	1
Basil: Sweet	1	1
Beans: All	1	1
Berries: All	1	1
Black Pepper	1	1
Boswellia	1	1
Broccoli Sprouts	1	1
Caffeoylquinic Acids	1	1
Cantaloupe	1	1
Canthaxanthin	1	1
Carotenoids	1	1
Carrot	1	1
Catechols	1	1
Celery seed	1	1
Cherry: All Varieties	1	1
Chickpea	1	1
Coriandrum sativum	1	1
Corn Silk	1	1
Cryptomeria japonica	1	1
Curcuma Longa	1	1
Damnacanthal	1	1
Deguelin	1	1
Devils Claw	1	1
Epicatechin	1	1
Estradiol (E(2))	1	1
Glucosamine	1	1
Guggul	1	1
Gynostemma	1	1
Hirudin (from Medicinal Leaches)	1	1
Horseradish	1	1
Ice Man Fungus	1	1
Juniper	1	1
Kimchi	1	1
Kombucha Tea	1	1
Lactobacillus helveticus	1	1
Legumes	1	1
Maple	1	1
Maple Syrup	1	1
Maqui	1	1
Meadowsweet	1	1
Modified Citrus Pectin	1	1

[+]

Alpha-lipoic acid supplementation had beneficial effects on inflammatory markers among patients with metabolic syndrome and related disorders.Dec 31, 2017

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Pubmed Data : Eur J Nutr. 2019 Mar 11. Epub 2019 Mar 11. PMID: 30854594

Article Published Date : Mar 10, 2019

Study Type : Meta Analysis

Additional Links

Substances : Probiotics

Diseases : Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-4 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

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Pubmed Data : ScientificWorldJournal. 2014 ;2014:563576. Epub 2014 Jan 22. PMID: 24578648

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Pubmed Data : Obesity (Silver Spring). 2014 Sep ;22(9):1981-8. Epub 2014 Jun 27. PMID: 24975522

Article Published Date : Aug 31, 2014

Study Type : Human Study

Additional Links

Substances : Peanut

Diseases : Inflammation, Obesity

Therapeutic Actions : Fasting/Caloric Restriction

Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

[+]

An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients. Jun 01, 2005

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Pubmed Data : Inflamm Bowel Dis. 2005 Jun;11(6):580-8. PMID: 15905706

Article Published Date : Jun 01, 2005

Study Type : Human Study

Additional Links

Diseases : Inflammation

Therapeutic Actions : Dietary Modification: Elemental Diet

Pharmacological Actions : Interleukin-1 receptor antagonist, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Click here to read the entire abstract

Pubmed Data : Blood Cells Mol Dis. 2009 Nov-Dec;43(3):298-303. Epub 2009 Sep 19. PMID: 19766513

Article Published Date : Nov 01, 2009

Study Type : Human Study

Additional Links

Substances : Bloodroot, Echinacea

Diseases : Immune Disorders: Low Immune Function, Low Immune Function: Exercise-Induced

Pharmacological Actions : Immunomodulatory, Immunostimulatory, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization.Jun 01, 2002

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Pubmed Data : J Nutr. 2002 Jun;132(6):1293-8. PMID: 12042449

Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.May 31, 2019

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Pubmed Data : Complement Ther Med. 2019 Jun ;44:204-209. Epub 2019 Apr 22. PMID: 31126557

Article Published Date : May 31, 2019

Study Type : Human Study

Additional Links

Substances : Nigella sativa (aka Black Seed)

Diseases : Nonalcoholic fatty liver disease (NAFLD)

Pharmacological Actions : Anti-Inflammatory Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

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Pubmed Data : Gynecol Endocrinol. 2017 Sep 26:1-6. Epub 2017 Sep 26. PMID: 28949260

Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335

Article Published Date : Jul 31, 2015

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Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780

Article Published Date : Jun 30, 2015

Study Type : Human Study

Additional Links

Substances : Bacillus coagulans

Diseases : C-Reactive Protein, Dysbiosis, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Microbiota

[+]

Dark chocolate has beneficial effects on serum adiponectin, biochemical and inflammatory parameters in diabetic patients.Dec 31, 2017

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Pubmed Data : Ann Allergy Asthma Immunol. 2003 Apr;90(4):371-7; quiz 377-8, 421. PMID: 12722956

Article Published Date : Apr 01, 2003

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Pubmed Data : Dermatol Ther. 2014 Sep-Oct;27(5):272-7. Epub 2014 Jun 9. PMID: 24910383

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Pubmed Data : Biol Trace Elem Res. 2017 Nov 10. Epub 2017 Nov 10. PMID: 29127547

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Pubmed Data : Arch Bronconeumol. 2009 Dec 30. Epub 2009 Dec 30. PMID: 20045240

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Pubmed Data : Breast Cancer Res Treat. 2016 Jan 28. Epub 2016 Jan 28. PMID: 26820653

Article Published Date : Jan 27, 2016

Study Type : Human Study

Additional Links

Diseases : Breast Cancer, Inflammation

Therapeutic Actions : Exercise, Exercise: Resistance Training

Pharmacological Actions : Anti-Inflammatory Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Click here to read the entire abstract

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Pubmed Data : Oman Med J. 2016 Jul ;31(4):263-9. PMID: 27403238

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Vitamin A deficiency is common in patients with common variable immunodeficiency and may respond favorably to vitamin A supplementation. May 01, 2005

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Pubmed Data : J Clin Immunol. 2005 May;25(3):275-80. PMID: 15981093

Article Published Date : May 01, 2005

Study Type : Human Study

Additional Links

Substances : Vitamin A

Diseases : Common variable immunodeficiency (CVID)

Pharmacological Actions : Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Vitamin C inhibited oxidative stress and proinflammatory mediators in severe pneumonia.Dec 31, 2013

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Pubmed Data : Curr Dev Nutr. 2019 Jun ;3(Suppl 1). Epub 2019 Jun 13. PMID: 31224358

Article Published Date : May 31, 2019

Study Type : Human Study

Additional Links

Substances : Apple

Diseases : Inflammation, Obesity, Overweight

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Wine consumption reduces TNF-apha-induced adhesion of monocytes to endothelial cells. Jan 01, 2010

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Pubmed Data : Cell Physiol Biochem. 2010;26(3):471-82. Epub 2010 Aug 24. PMID: 15213052

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Pubmed Data : Int J Food Sci Nutr. 2018 Jul 2:1-10. Epub 2018 Jul 2. PMID: 29962254

Article Published Date : Jul 01, 2018

Study Type : Human Study

Additional Links

Substances : Yerba Mate

Diseases : Inflammation, Oxidative Stress

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

Zinc supplementation has a beneficial effect on malaise, one of the influenza vaccine associated adverse events, and decrease serum TNF-α levels.Apr 21, 2011

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Pubmed Data : J Trace Elem Med Biol. 2011 Apr 21. Epub 2011 Apr 21. PMID: 21514808

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Pubmed Data : Nutr Res Pract. 2013 Feb ;7(1):9-14. Epub 2013 Feb 4. PMID: 23422838

Article Published Date : Jan 31, 2013

Study Type : Human In Vitro

Additional Links

Substances : Bamboo

Diseases : Cardiovascular Diseases, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

[+]

Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.Dec 31, 2010

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Pubmed Data : Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID: 30121057

Pubmed Data : Pak J Pharm Sci. 2018 Sep ;31(5(Supplementary)):2109-2117. PMID: 30393220

Article Published Date : Aug 31, 2018

Study Type : Animal Study

Additional Links

Diseases : Cardiomyopathy, Diabetic Nephropathy

Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, NF-kappaB Inhibitor, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

[+]

A Burdock extract was able to reduce intestinal inflammation in an acute TNBS-induced experimental model of colitis in rats.Mar 06, 2013

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Pubmed Data : J Ethnopharmacol. 2013 Mar 7 ;146(1):300-10. Epub 2013 Jan 10. PMID: 23313393

Article Published Date : Mar 06, 2013

Study Type : Animal Study

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Substances : Burdock

Diseases : Colitis

Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Phytotherapy, Plant Extracts

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A cocoa enriched diet produces an immunomodulatory effect that prevents anti-allergen IgE synthesis.May 31, 2012

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Pubmed Data : Pharmacol Res. 2012 Jun ;65(6):603-8. Epub 2012 Feb 10. PMID: 22342543

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Pubmed Data : Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID: 29128856

Article Published Date : Dec 31, 2017

Study Type : Animal Study

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Substances : Chlorogenic Acid

Diseases : Chemically-Induced Liver Damage

Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : Springerplus. 2015 ;4:438. Epub 2015 Aug 21. PMID: 26312203

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An extract of Musa sapientum fruit showed antidiabetic and better ulcer healing effects compared with omeprazole.Nov 04, 2013

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Pubmed Data : J Ethnopharmacol. 2009 May 4 ;123(1):149-54. Epub 2009 Feb 14. PMID: 19429354

Article Published Date : May 03, 2009

Study Type : Animal Study

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Substances : Chrysanthemum Morifolium

Diseases : Dermatitis, Inflammation

Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

Additional Keywords : Plant Extracts

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Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.Dec 31, 2017

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Pubmed Data : Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID: 31141940

Article Published Date : May 27, 2019

Study Type : Animal Study

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Substances : Honokiol

Diseases : Depression, Lipopolysaccharide-Induced Toxicity

Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.Apr 30, 2018

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Pubmed Data : Nutrients. 2016 Sep 18 ;8(9). Epub 2016 Sep 18. PMID: 27649243

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Pubmed Data : Chem Biol Interact. 2016 Aug 24. Epub 2016 Aug 24. PMID: 27567545

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Pubmed Data : J Pharmacol Exp Ther. 2001 Dec;299(3):832-9. PMID: 11714866

Article Published Date : Dec 01, 2001

Study Type : Animal Study

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Substances : Arginine

Diseases : Alcoholic Liver Disease, Inflammation, Liver Fibrosis

Pharmacological Actions : Cyclooxygenase 2 Inhibitors, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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Pubmed Data : J Nutr Biochem. 2016 Mar 2 ;43:27-35. Epub 2016 Mar 2. PMID: 28193580

Article Published Date : Mar 01, 2016

Study Type : Animal Study

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Substances : Astaxanthin

Diseases : Hepatic Steatosis, High Fat Diet, High Sugar Diet, Inflammation, Liver Fibrosis

Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Hepatoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor

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View the Evidence: 1992 Abstracts with Tumor Necrosis Factor (TNF) Alpha Inhibitor Research

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Alpha-lipoic acid supplementation had beneficial effects on inflammatory markers among patients with metabolic syndrome and related disorders.Dec 31, 2017

Coenzyme Q10 could have significant inflammatory lowering effects.Feb 04, 2017

Coenzyme Q10 supplementation may partly improve the process of inflammatory state.Dec 31, 2016

Eicosapentaenoic acid and docosahexaenoic acid supplementation may increase adiponectin and reduce TNF-α levels.Mar 31, 2018

Flaxseed significantly reduced circulating concentrations of high-sensitivity-CRP and TNFα.May 21, 2019

Garlic supplementation reduces circulating C-reactive protein, tumor necrosis factor, and interleukin-6 in adults.Mar 31, 2019

Mind-body therapies reduce markers of inflammation and influence virus-specific immune responses to vaccination.Dec 31, 2013

Probiotic supplementation significantly reduced serum concentrations of pro-inflammatory cytokines.Mar 10, 2019

Supplementation of fish oil may reduce the circulating levels of TNF-α, IL-1 and IL-6 in patients with chronic heart failure.Dec 31, 2011

This meta-analysis of RCTs suggested a significant effect of curcumin in lowering circulating TNF-α concentration.Mar 25, 2016

Vitamin D supplementation may decrease serum levels of parathyroid hormone and inflammatory mediators in patients with chronic heart failure.Sep 27, 2015

A combination of aerobic exercise and resistance training was effective in reducing inflammation.Mar 01, 2017

A combination of lactobacillus reuteri and lactobacillus rhamnosus reduces inflammation in patients with Crohn's disease or ulcerative colitis.Sep 01, 2007

A combined nutraceutical showed to improve lipid and glucose metabolism, adipokines pattern, and systemic inflammation in dyslipidemic overweight subjects.Jul 31, 2019

A dietary mixture of sesame, pumpkin and flax seed added to a habitual diet lowered triglyceride and CRP, TNF-alpha, IL-6 levelsDec 31, 2013

A moderate carbohydrate diet with psyllium reduces fasting plasma insulin and tumor necrosis factor-α in patients with type 2 diabetes mellitus.Jul 03, 2018

A standardized preparation of curcuminoids compares favorably with atorvastatin on endothelial dysfunction in association with reductions in inflammatory cytokines and markers of oxidative stress. Jan 01, 2008

Acute high-oleic peanut consumption leads to stronger moderation of postprandial glucose, insulin, and TNF-α concentrationsAug 31, 2014

Adherence to a Mediterranean dietary pattern may protect against coronary artery wall production of inflammatory mediators in patients with unstable angina pectoris. Sep 01, 2005

Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults.Jul 07, 2004

Aged garlic extract was highly tolerable with a high safety profile as a stand-alone or adjunctive antihypertensive treatment.Dec 31, 2015

An anthocyanin-rich bilberry extract is a promising therapeutic approach for the treatment of IBD.Dec 31, 2015

An elemental diet reduces mucosal inflammation in patients with active Crohn's disease with remission occuring in 71% of patients. Jun 01, 2005

Association of endodontic infection with detection of an initial lesion to the cardiovascular system.Nov 30, 2011

Astaxanthin addition improves human neutrophils function.Dec 01, 2010

Astragalus improves cardiac function in aged patients with Chronic Heart Failure.Sep 01, 2005

Astragalus may significantly improve Chronic Aplastic Anemia via recovery of hemopoietic function.May 01, 2004

Bacillus coagulans increased immune response (enhanced T-cell response) to viral challenge.Mar 01, 2009

Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD.Nov 30, 2018

Berberine promoted myocardial protection of postoperative patients through regulating myocardial autophagy.Aug 31, 2018

Bloodroot and echinacea offset exercise-associated effects of immune activity.Nov 01, 2009

Breastfeeding attenuates reductions in energy intake induced by a mild immunologic stimulus represented by DPTH immunization.Jun 01, 2002

Breastfeeding protects against illness-induced anorexia and is mediated partially by docosahexaenoic acid.Jan 01, 2008

Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology.Sep 30, 2016

Cannabis use significantly reduces symptoms, and reduces the requirements for drugs and surgery in subjects with Crohn's disease. Aug 01, 2011

Cardamonin is a potential candidate for controlling inflammation during primary Sjögren's syndrome.Mar 31, 2018

Cats claw is an effective treatment for osteoarthritis.Sep 01, 2001

Chaihu Shihuang soup can significantly regulate cytokine and improve early recovery of severe acute pancratitis.May 31, 2009

Children with atopic dermatitis show clinical improvement after Lactobacillus exposure.Mar 31, 2015

Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime.Jul 01, 2002

Coenzyme Q10 might have a role as a good supplement in young children with Down syndrome to ameliorate the neurological symptoms.Oct 18, 2016

Combined therapy regulates the inflammatory process and oxidative stress and contributes to immune protection on patients with T2D.May 07, 2018

Consumption of chokeberry products modestly lowered blood pressure and reduced low-grade inflammation.Oct 31, 2016

Consumption of Nigella sativa can reduce the inflammatory biomarkers in patients with NAFLD.May 31, 2019

CoQ10 intake for 12 weeks in PCOS women significantly improved gene expression of LDLR, PPAR-γ, IL-1, IL-8 and TNF-α.Sep 25, 2017

CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.Apr 30, 2015

CoQ10 supplementation reduced calcitonin gene-related peptide and TNF-α significantly.Jan 02, 2018

Curcumin could be used for improving nasal airflow and modulating immune response in patients with allergic rhinitis.Nov 30, 2016

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

Curcumin supplementation significantly decreases serum concentrations of pro-inflammatory cytokines in subjects with MetS.Jun 05, 2016

Cycling and Tai Chi Chuan exercises suppress human hepatitis B virus surface antigen. Nov 05, 2008

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

Dark chocolate has beneficial effects on serum adiponectin, biochemical and inflammatory parameters in diabetic patients.Dec 31, 2017

DHA supplementation reduces the production of inflammatory mediators and decreases the adverse effect of infection on appetite. Jan 01, 2006

DHEA administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients. Mar 01, 2009

Dietary lipids and their inflammatory potential may be implicated in the link between elevated body mass and asthma. Apr 01, 2003

Dietary soy improves the inflammatory and nutritional status in end-stage renal disease patients on chronic hemodialysisAug 01, 2006

Double fill nine tastes soup has significant effects in treating recurrent respiratory infection (RRI) and enhance the immune function in children.Mar 31, 2012

Echinacea modules human gene expression in a manner consistent with its reported ability to reduce both the duration and intensity of cold and flu symptoms.Oct 01, 2003

Effect of diosmin administration in patients with chronic venous disorders on selected factors affecting angiogenesis.Sep 11, 2019

Electroacupuncture at Lieque, Chize, and Zusanli can lessen the lung injury induced by severe acute pancreatitis.Dec 31, 2016

Electroacupuncture can significantly decrease permeability of intestinal mucosa in the patients with acute pancreatitis.Jun 01, 2007

Electroacupuncture has a therapeutic effect on patients wtih osteoarthritis. Jul 01, 2009

Exercise reduces depression and inflammation but intensity matters.Feb 28, 2018

Far infrared therapy inhibits vascular endothelial inflammation via the induction of heme oxygenase-1.Mar 31, 2008

Fasting and a one-year vegetarian diet can reduce disease activity in some patients with rheumatoid arthritis.Jan 01, 1995

Fish oil supplementation decreases serum soluble receptor activator of nuclear factor-kappa B ligand/osteoprotegerin ratio in female patients with rheumatoid arthritis.Dec 21, 2009

Fish oil supplementation for 6 weeks in women with gestational diabetes significantly improved gene expression of PPAR-γ, IL-1, and TNF-α.Jan 30, 2018

Folic acid supplementation mitigates Alzheimer's disease by reducing inflammation.Dec 31, 2015

Forest bathing has therapeutic effects on human hypertension and induces inhibition of the renin–angiotensin system and inflammation.Nov 30, 2012

Forest bathing is beneficial to human health.May 31, 2012

Garlic supplementation for 12 weeks might reduce pain severity in overweight or obese women with knee osteoarthritis.Sep 14, 2018

Tumor Necrosis Factor (TNF) Alpha Inhibitor

View the Evidence:
1992 Abstracts with Tumor Necrosis Factor (TNF) Alpha Inhibitor Research