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Matrix metalloproteinase-9 (MMP-9) inhibitor
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205 Substances Researched for Matrix metalloproteinase-9 (MMP-9) inhibitor
Name
AC
CK
Focus
Curcumin
24
34
Ginsenosides
11
22
Resveratrol
10
22
EGCG (Epigallocatechin gallate)
3
13
Pomegranate
3
13
Genistein
2
12
Quercetin
8
12
Pycnogenol (Pine Bark)
2
11
Baicalein
8
10
Berberine
7
10
Cannabinoids
1
10
Cannabis
1
10
Coenzyme Q10
1
10
Purslane
1
10
Luteolin
5
8
Red Sage
4
8
Sulforaphane
6
8
Fucoidan
5
7
Melatonin
6
7
Parthenolide
2
7
Vitamin C
4
7
Aloe Vera
3
6
Chrysanthemum Indicum
2
6
EPA (Eicosapentaenoic Acid)
3
6
Ginseng
2
6
Naringenin
5
6
Piperine
2
6
Ellagic Acid
3
5
Feverfew
1
5
Green Tea
3
5
Nobiletin
4
5
Polyphenols
3
5
Shikonin
1
5
Tanshinone IIA
4
5
Verbascoside
3
5
Wogonin
5
5
Apigenin
3
4
Chrysin
3
4
Omega-3 Fatty Acids
2
4
Paeoniflorin
3
4
Sesamol
2
4
Theaflavins
3
4
Thymoquinone
4
4
Allicin
2
3
Benzyl isothiocyanate
3
3
Cannabinoids: Synthetic
2
3
Chaga Mushroom (Inonotus obliquus)
2
3
Cucurbitacin B
3
3
Deguelin
3
3
Fisetin
3
3
Ginger
2
3
Ginseng (Korean)
2
3
Huaier (Trametes robiniophila murr)
3
3
Phloretin
3
3
Rose
2
3
Tomato
2
3
Ursolic Acid
2
3
Zerumbone
2
3
Acai
1
2
Anthocyanins
2
2
Arctigenin
2
2
Asiatic Acid
1
2
Astaxanthin
1
2
Astragaloside
2
2
Bamboo
1
2
Bee Propolis
1
2
Berries: All
1
2
Beta-Elemene
2
2
Bisdemethoxycurcumin
2
2
Black Pepper
1
2
Boswellia
1
2
Burdock
2
2
Caffeic acid phenethyl ester
1
2
Cannabidiol
1
2
Citrus naringin
1
2
Cysteine (see N-Acetylcysteine)
1
2
D-Limonene
1
2
DHA (Docosahexaenoic Acid)
1
2
Eggplant
2
2
Emodin
1
2
Fermented Foods and Beverages
1
2
Fig
1
2
Flavonoids
1
2
Gallic Acid
2
2
Genipin
1
2
Ginkgo biloba
1
2
Grape
1
2
Grape Seed Extract
1
2
Hesperidin
2
2
Hibiscus sabdariffa
1
2
Hydrogen Water
1
2
Isothiocyanates
2
2
Kaempferia parviflora
1
2
Kaempferol
1
2
Ligustrazine
1
2
Long Pepper
1
2
Loquat Leaves
2
2
Lotus
2
2
Lycopene
1
2
Lysine
1
2
Magnolol
2
2
Mangiferin
1
2
Manuka Honey
2
2
Mulberry
1
2
Myricetin
1
2
Noni
1
2
Palmitoylethanolamide
1
2
Phyllanthus amarus
2
2
Phyllanthus niruri (Stonebreaker)
2
2
Phyllanthus urinaria
2
2
Piceatannol
2
2
Pine Bark Extract
2
2
Polyunsaturated Fatty Acids (PUFAs)
1
2
Poria cocos
2
2
Probiotics
1
2
Proline
1
2
Propolis: Bee
1
2
Prunella vulgaris
2
2
Psychedelics:All
2
2
Punicalagin
2
2
Reishi Mushroom
2
2
Rhubarb
2
2
Rosmarinic acid
2
2
Saffron
1
2
Sea Cucumber
1
2
Sea buckthorn
1
2
Stilbenes
2
2
Thuja
1
2
Tocotrienol: Delta
2
2
Triptolide
1
2
Turmeric
2
2
Vitamin E: Gamma-tocotrienol
1
2
Vitamin E: alpha tocopherol
1
2
Vitamin K
1
2
Yoghurt
1
2
6-Shogaol
1
1
Achillea fragrantissima
1
1
Agaricus Blazei
1
1
Apple Polyphenols
1
1
Ashwagandha
1
1
Bee Venom
1
1
Betulinic acid
1
1
Black Tea
1
1
Blackberry
1
1
Blueberry
1
1
Bromelain
1
1
Bufalin
1
1
Capsaicin
1
1
Catechin
1
1
Chili pepper
1
1
Cordyceps Militaris
1
1
Diosgenin
1
1
Enterolactone
1
1
False Black Pepper
1
1
Ferulic acid
1
1
Frankincense
1
1
Fruit: All
1
1
Gac
1
1
Garcinia Mangostana
1
1
Garlic
1
1
Germanium
1
1
Guggul
1
1
Holy Basil
1
1
Honeybush
1
1
Hops
1
1
Hydroxytyrosol
1
1
Juniper
1
1
Justicia gendarussa
1
1
Licorice
1
1
Lion's Mane (Hericium Erinaceus)
1
1
Lychee
1
1
Magnolia
1
1
Medicinal Mushrooms
1
1
Milk Thistle
1
1
Nettle
1
1
Oleuropein
1
1
Olive leaf extract
1
1
Pachymic acid
1
1
Palash
1
1
Panax Notoginseng
1
1
Papain
1
1
Passion Flower
1
1
Peach
1
1
Phenethyl isothiocyanate
1
1
Pomegranate Peel
1
1
Pterostilbene
1
1
Puerarin
1
1
Rice: Black
1
1
Rutin
1
1
Schisandra
1
1
Silibinin
1
1
Syrian rue
1
1
Thistle
1
1
Thymol
1
1
Tomatidine
1
1
Toona sinensis
1
1
Turmerones
1
1
Tyrosol
1
1
Vegetables: All
1
1
Vitex negundo
1
1
Water: Deep Sea
1
1
Water: Deuterium Depleted
1
1
Wheat Grass
1
1
White Mulberry
1
1
Xanthohumol
1
1
Research Articles
337
Cumulative Knowledge Score
545
Overall Research Rating
EXCELLENT
View the Evidence:
392 Abstracts with Matrix metalloproteinase-9 (MMP-9) inhibitor Research
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[+]
A vegetarian diet is associated with a healthier profile of cardiovascular biomarkers compared to omnivorous.
Aug 01, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Chim Acta. 2016 Aug 2 ;461:110-113. Epub 2016 Aug 2. PMID:
27496081
Article Published Date
: Aug 01, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Disease: Prevention
,
Cardiovascular Diseases
Therapeutic Actions
:
Dietary Modification: Vegetarian
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Risk Reduction
[+]
Aerobic training and purslane seed ere effective in the regulation of diabetic biomarkers associated with atherosclerosis in women with T2D.
Dec 04, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 Dec 5 ;6:37819. Epub 2016 Dec 5. PMID:
27917862
Article Published Date
: Dec 04, 2016
Study Type
: Human Study
Additional Links
Substances
:
Purslane
Diseases
:
Atherosclerosis
,
Diabetes Mellitus: Type 2
Therapeutic Actions
:
Exercise: Aerobic
Pharmacological Actions
:
Hypoglycemic Agents
,
Hypolipidemic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
NF-kappaB Inhibitor
,
Uricosuric Agents
Additional Keywords
:
Risk Reduction
[+]
CoQ10 supplementation at a dosage of 500 mg appears to decrease inflammatory markers in patients with MS.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Neurosci. 2015 May ;18(4):169-76. Epub 2014 Jan 10. PMID:
24621064
Article Published Date
: Apr 30, 2015
Study Type
: Human Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Epigallocatechin gallate could potentially be used as a supplement of traditional rt-PA treatment among stroke patients.
Dec 08, 2016
Click here to read the entire abstract
Pubmed Data
: Clin Neuropharmacol. 2016 Dec 9. Epub 2016 Dec 9. PMID:
27941526
Article Published Date
: Dec 08, 2016
Study Type
: Human Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Brain Ischemia
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Fisetin prolongs therapy window of brain ischemic stroke using tissue plasminogen activator.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Clin Appl Thromb Hemost. 2019 Jan-Dec;25:1076029619871359. PMID:
31434498
Article Published Date
: Dec 31, 2018
Study Type
: Human Study
Additional Links
Substances
:
Fisetin
Diseases
:
Stroke: Ischemic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
French maritime pine bark extract (Pycnogenol) displays anti-inflammatory effects in vivo.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Inflamm (Lond). 2006;3:1. Epub 2006 Jan 27. PMID:
16441890
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Substances
:
Pycnogenol (Pine Bark)
Diseases
:
Inflammation
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Hesperidin reduces adverse symptomatic intracerebral hemorrhage.
Sep 01, 2019
Click here to read the entire abstract
Pubmed Data
: Neurol Sci. 2019 Sep 2. Epub 2019 Sep 2. PMID:
31478148
Article Published Date
: Sep 01, 2019
Study Type
: Human Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Cerebral Hemorrhage
,
Stroke: Ischemic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Transforming growth factor beta (TGF-β) inhibitor
[+]
Pomegranate juice significantly modulates matrix metalloproteinases 2 and 9 and serum levels of inflammatory factors protecting against exercise induced oxidative injury.
Jun 30, 2014
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2014 Jul ;64(7):785-90. PMID:
25255587
Article Published Date
: Jun 30, 2014
Study Type
: Human Study
Additional Links
Substances
:
Pomegranate
Diseases
:
Oxidative Stress
Pharmacological Actions
:
Anti Inflammatory
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Prolonged Exercise
[+]
Regular probiotic yoghurt consumption guarded against exhaustive exercise-inducing oxidative injury in young healthy females.
Nov 30, 2018
Click here to read the entire abstract
Pubmed Data
: J Pak Med Assoc. 2018 Dec ;68(12):1748-1754. PMID:
30504936
Article Published Date
: Nov 30, 2018
Study Type
: Human Study
Additional Links
Substances
:
Yoghurt
Diseases
:
Inflammation
,
Muscle Damage: Exercise-Induced
,
Oxidative Stress
Therapeutic Actions
:
Exercise
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol and genistein may be potential drugs candidates for use in the treatment of COPD.
Mar 27, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Mar 28. Epub 2016 Mar 28. PMID:
27035424
Article Published Date
: Mar 27, 2016
Study Type
: Human Study
Additional Links
Substances
:
Genistein
,
Resveratrol
Diseases
:
Chronic Obstructive Pulmonary Disease
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
The anti-inflammatory activity of Cannabis extracts on colon epithelial cells derives from a fraction of the extract that contains THCA.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cannabis Cannabinoid Res. 2017 ;2(1):167-182. Epub 2017 Jul 1. PMID:
29082314
Article Published Date
: Dec 31, 2016
Study Type
: Human Study
Additional Links
Substances
:
Cannabinoids
,
Cannabis
Diseases
:
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside 20(S)-Rh2 has therapeutic potential for the treatment with colorectal cancer.
Dec 23, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Dec 24 ;194:83-90. Epub 2016 Aug 23. PMID:
27566200
Article Published Date
: Dec 23, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Ginseng
,
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemosensitizer
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Doxorubicin
[+]
Parthenolide is a potential novel therapeutic agent for aggressive colorectal cancer treatment.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Intest Res. 2017 Apr ;15(2):174-181. Epub 2017 Apr 27. PMID:
28522946
Article Published Date
: Mar 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Feverfew
,
Parthenolide
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Piperine inhibits the proliferation of human osteosarcoma cells via G2/M phase arrest and prevents metastasis.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2015 Jan ;24(1):50-8. Epub 2014 Nov 20. PMID:
25479727
Article Published Date
: Dec 31, 2014
Study Type
: Human In Vitro
Additional Links
Substances
:
Piperine
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Shikonin and temozolomide may constitute a powerful new tool for Glioblastoma treatment by reducing therapy resistance and tumor recurrence.
Apr 10, 2017
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2017 Apr 11. Epub 2017 Apr 11. PMID:
28401486
Article Published Date
: Apr 10, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Shikonin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Antiproliferative
,
Chemotherapeutic Synergy: Temozolomide
,
Glioblastoma
,
Shikonin
[+]
Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoaging
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cytotechnology. 2016 Mar ;68(2):229-40. Epub 2014 Jul 23. PMID:
25052044
Article Published Date
: Feb 29, 2016
Study Type
: Human In Vitro
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Berberin inhibited colorectal cancer invasion and metastasis via down regulation of COX-2/PGE2- JAK2/STAT3 signaling pathway.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(5):e0123478. Epub 2015 May 8. PMID:
25954974
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
[+]
A low molecular-weight gel fraction of Aloe vera has the potential to alleviate alcohol-induced acute gastric lesions.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):2110-2115. PMID:
28874080
Article Published Date
: Nov 30, 2017
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Alcohol Toxicity
Pharmacological Actions
:
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
A specific mixture of nutrients suppresses ovarian cancer A-2780 tumor incidence, growth, and metastasis to lungs.
Mar 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2017 Mar 18 ;9(3). Epub 2017 Mar 18. PMID:
28335466
Article Published Date
: Mar 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Green Tea
,
Lysine
,
Proline
,
Quercetin
,
Vitamin C
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Açaí is a promising novel pharmacological therapeutic treatment for endometriosis.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2016 ;11(11):e0166059. Epub 2016 Aug 16. PMID:
27851787
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Acai
Diseases
:
Endometriosis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Nitric Oxide Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Administration of N- acetylcysteine and genistein have an additive gastroprotective effect in indomethacin induced gastric injury.
Jul 15, 2018
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2018 Jul 16. Epub 2018 Jul 16. PMID:
30011378
Article Published Date
: Jul 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cysteine (see N-Acetylcysteine)
,
Genistein
Diseases
:
Drug-Induced Toxicity: Indomethacin
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Allicin inhibits the proliferation and invasion in cholangiocarcinoma.
May 21, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 May 22 ;47(2):641-653. Epub 2018 May 22. PMID:
29794468
Article Published Date
: May 21, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
An aqueous extract of bamboo exerts anti-metastatic effects on highly malignant cancer.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2013 ;8(10):e78061. Epub 2013 Oct 28. PMID:
24205091
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Bamboo
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anti-inflammatory activity of hydroalcoholic extracts of Lavandula dentata L. and Lavandula stoechas L.
Aug 21, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 Aug 22 ;190:142-58. Epub 2016 Jun 4. PMID:
27269390
Article Published Date
: Aug 21, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Lavender
Diseases
:
Colitis
,
Gastrointestinal Inflammation
,
Inflammatory Bowel Diseases
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Antitumor activity of ginsenoside Rg3 in melanoma through downregulation of the ERK and Akt pathways.
May 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2019 Jun ;54(6):2069-2079. Epub 2019 Apr 16. PMID:
31081060
Article Published Date
: May 31, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Melanoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Apoptosis induction and ERK/NF-κB inactivation are associated with magnolol-inhibited tumor progression in hepatocellular carcinoma.
Nov 11, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2019 Nov 12. Epub 2019 Nov 12. PMID:
31714653
Article Published Date
: Nov 11, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Magnolol
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Application of curcumin can inhibit expression of MMP-9, CD40L, TNF-α and CRP to improve the permeability of coronary artery.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Pathol. 2015 ;8(6):7247-53. Epub 2015 Jun 1. PMID:
26261622
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Atherosclerosis
,
C-Reactive Protein
,
Coronary Artery Disease
,
High Fat Diet
Pharmacological Actions
:
Cardiovascular Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Arctigenin attenuates tumor metastasis of hepatocellular carcinoma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:937. Epub 2019 Aug 29. PMID:
31555129
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Arctigenin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Ascorbic acid may be considered as a useful candidate to reduce the side effects of delayed application of ecombinant tissue plasminogen activators in stroke therapy.
Apr 20, 2015
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2015 Apr 21. Epub 2015 Apr 21. PMID:
25899606
Article Published Date
: Apr 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
Diseases
:
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Astaxanthin reduces matrix metalloproteinase-9 expression and activity in the brain after experimental subarachnoid hemorrhage.
Oct 21, 2015
Click here to read the entire abstract
Pubmed Data
: Brain Res. 2015 Oct 22 ;1624:113-24. Epub 2015 Jul 23. PMID:
26210617
Article Published Date
: Oct 21, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Subarachnoid hemorrhage
Pharmacological Actions
:
Malondialdehyde Down-regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Baicalein alleviated myocardial remodelling and improved cardiac function.
Jan 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jan 15 ;145:213-23. Epub 2015 Dec 17. PMID:
26706290
Article Published Date
: Jan 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Heart Failure
Pharmacological Actions
:
Anti-Apoptotic
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberine attenuates experimental autoimmune encephalomyelitis in mice.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2010;5(10):e13489. Epub 2010 Oct 19. PMID:
20976070
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Blood-Brain-Barrier Disorders
,
Brain Inflammation
,
Multiple Sclerosis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Blue LED irradiation inhibits cancer cell migration and invasion in vitro and in vivo.
Jan 17, 2017
Click here to read the entire abstract
Pubmed Data
: J Cell Physiol. 2017 Jan 18. Epub 2017 Jan 18. PMID:
28098340
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Colon Cancer
,
Fibrosarcoma
Therapeutic Actions
:
Light-Emitting Diodes (LEDs) Therapy
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Boswellic acid suppresses growth and metastatis of human pancreatic tumors (nude mouse model).
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011 ;6(10):e26943. Epub 2011 Oct 31. PMID:
22066019
Article Published Date
: Jan 01, 2011
Study Type
: Transgenic Animal Study
Additional Links
Substances
:
Boswellia
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Caffeic acid phenethyl ester may be a potential therapeutic agent for patients with advanced PCa.
May 14, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 May 15. Epub 2016 May 15. PMID:
27191743
Article Published Date
: May 14, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Bee Propolis
,
Caffeic acid phenethyl ester
Diseases
:
Cancer Metastasis
,
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Carnosol may represent a promising therapeutic candidate that canmodulate breast cancer growth and metastasis.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Oncol. 2019 ;9:743. Epub 2019 Aug 8. PMID:
31456939
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carnosol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Anat. 2019 Mar ;222:120-128. Epub 2018 Dec 24. PMID:
30590121
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Safflower
Diseases
:
Hypertension
Pharmacological Actions
:
Cardioprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
CBD can be used as a novel therapeutic option to inhibit growth and metastasis of highly aggressive breast cancer subtypes including TNBC.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Oncol. 2015 Apr ;9(4):906-19. Epub 2015 Jan 19. PMID:
25660577
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Epidermal growth factor receptor (EGFR) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Chrysin attenuates interstitial fibrosis and improves cardiac function in a rat model of acute myocardial infarction.
Sep 16, 2018
Click here to read the entire abstract
Pubmed Data
: J Mol Histol. 2018 Sep 17. Epub 2018 Sep 17. PMID:
30225683
Article Published Date
: Sep 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
Fibrosis
,
Myocardial Infarction
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Components of Salvia miltiorrhiza Bunge, could inhibit the development of elastase-induced experimental abdominal aortic aneurysms.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2012 Dec ;178(2):1029-37. Epub 2012 May 17. PMID:
22640888
Article Published Date
: Nov 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aneurysm: Aortic
,
Hypertension
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Cordyceps militaris fraction inhibits the invasion and metastasis of lung cancer cells
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2018 Dec ;16(6):6930-6939. Epub 2018 Sep 27. PMID:
30546425
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cordyceps Militaris
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Cucurbitacin B inhibited breast cancer metastasis and angiogenesis.
May 18, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Biochem Cell Biol. 2016 May 19 ;77(Pt A):41-56. Epub 2016 May 19. PMID:
27210504
Article Published Date
: May 18, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin alleviates matrix metalloproteinases associated with inflammation during eradication of H. pylori infection.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: PLoS One. 2011;6(1):e16306. Epub 2011 Jan 21. PMID:
21283694
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Helicobacter Pylori Infection
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin can significantly decrease cerebral ischemia reperfusions pathological damage and suppressed the expression of MMP-9 and TNF-α.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Zhong Yao Cai. 2015 Feb ;38(2):344-9. PMID:
26415414
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin could restore the core and associated symptoms of the autistic phenotype by suppressing oxidative-nitrosative stress, mitochondrial dysfunction in PPA-induced autism in rats.
Sep 22, 2015
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2015 Sep 23. Epub 2015 Sep 23. PMID:
26407474
Article Published Date
: Sep 22, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Autism Spectrum Disorders
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuromodulatory
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Dose Response
[+]
Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis.
Sep 07, 2010
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2010 Sep 7. Epub 2010 Sep 7. PMID:
20824699
Article Published Date
: Sep 07, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-Proliferative
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Curcumin inhibits the growth of choroidal melanoma.
Jan 15, 2011
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2011 Jan 15;11(2):229-35. Epub 2011 Jan 15. PMID:
21084858
Article Published Date
: Jan 15, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Melanoma
,
Melanoma: Choroidal
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin's antiulcer activity is primarily attributed to MMP-9 inhibition, one of the major path-ways of ulcer healing.
Mar 11, 2005
Click here to read the entire abstract
Pubmed Data
: J Biol Chem. 2005 Mar 11;280(10):9409-15. Epub 2004 Dec 22. PMID:
15615723
Article Published Date
: Mar 11, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Gastric Ulcer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Ulcer Agents
,
Gastroprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Drug: Indomethacin
[+]
D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2017 Apr ;15(4):2339-2346. Epub 2017 Feb 22. PMID:
28260017
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
D-Limonene
Diseases
:
Ulcerative Colitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Postaglandin PGE2 downregulation
[+]
Dendrosomal curcumin has a chemoprotective effect on the breast cancer metastasis through suppression of NF-κB and its regulated gene products.
Jul 04, 2015
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2015 Jul 5 ;758:188-96. Epub 2015 Apr 8. PMID:
25863259
Article Published Date
: Jul 04, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Dietary intake of EPA and DHA prevented abdominal aortic aneurysm development.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Circ J. 2015 ;79(7):1470-8. Epub 2015 Apr 30. PMID:
25925976
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
,
EPA (Eicosapentaenoic Acid)
,
Omega-3 Fatty Acids
Diseases
:
Aneurysm: Aortic
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Dietary supplementation with n-3 PUFAs may have protective anti-inflammatory effects mediated through modulation of MMPs and TIMPs.
Mar 31, 2015
Click here to read the entire abstract
Pubmed Data
: Heart Lung Circ. 2015 Apr ;24(4):377-85. Epub 2014 Nov 20. PMID:
25512019
Article Published Date
: Mar 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Omega-3 Fatty Acids
,
Polyunsaturated Fatty Acids (PUFAs)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effect of hyperbaric oxygen treatment in a rat model of abdominal aortic aneurysm.
Dec 31, 2013
Click here to read the entire abstract
Pubmed Data
: Undersea Hyperb Med. 2014 Jan-Feb;41(1):9-15. PMID:
24649712
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Aneurysm: Aortic
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
EGCG inhibited SW780 bladder cancer tumor growth by down-regulation of NF-κB and MMP-9.
Dec 19, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2016 Dec 20 ;41:56-64. Epub 2016 Dec 20. PMID:
28040581
Article Published Date
: Dec 19, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
EGCG (Epigallocatechin gallate)
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Ellagic acid may be beneficial for the treatment of glioblastoma.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Feb ;37(2):1084-1092. Epub 2016 Dec 22. PMID:
28035411
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
Diseases
:
Glioblastoma
Pharmacological Actions
:
Antiproliferative
,
Bcl-2 protein down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Emodin exerts anti-metastatic activity in pancreatic cancer both in vitro and in vivo.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2011 Nov ;36(22):3167-71. PMID:
22375400
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Emodin
Diseases
:
Cancer Metastasis
,
Pancreatic Cancer
,
Pancreatic Cancer: Metastatic
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Endostar combined with ginsenoside Rg3 has stronger inhibiting effect on breast cancer tumor growth in tumor-bearing mice than single drug.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2016 Feb ;9(2):180-3. Epub 2016 Jan 11. PMID:
26919952
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
,
Vascular Endothelial Growth Factor C Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
EPA prevents the development of abdominal aortic aneurysms.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2016 ;11(10):e0165132. Epub 2016 Oct 20. PMID:
27764222
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fucoidan suppresses hypoxia-induced lymphangiogenesis and lymphatic metastasis in mouse hepatocarcinoma.
Jun 02, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2015 Jun 3 ;13(6):3514-30. Epub 2015 Jun 3. PMID:
26047481
Article Published Date
: Jun 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Hypoxia
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Genipin inhibits allergic responses in ovalbumin-induced asthmatic mice.
Nov 30, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Dec ;53:49-55. Epub 2017 Oct 15. PMID:
29035815
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Genipin
Diseases
:
Asthma
Pharmacological Actions
:
Anti-Asthmatic Agents
,
Cyclooxygenase 2 Inhibitors
,
interleukin-13 down-regulation
,
Interleukin-5 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg1 may represent a novel treatment target for spinal cord injury.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2017 ;40(10):1630-1637. PMID:
28966235
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 decreases fibrotic and invasive nature of endometriosis.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Dec 15 ;7(1):17670. Epub 2017 Dec 15. PMID:
29247225
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Endometriosis
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
[+]
Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer.
Aug 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2014 Sep ;45(3):1065-72. Epub 2014 Jun 16. PMID:
24938458
Article Published Date
: Aug 31, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 inhibits migration and invasion, and promotes apoptosis of Caco-2 cells.
Jan 07, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Mol Pathol. 2019 Jan 8 ;106:131-138. Epub 2019 Jan 8. PMID:
30633886
Article Published Date
: Jan 07, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 might be a useful agent for the treatment of metastatic thyroid cancers.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):849-857. Epub 2018 Aug 23. PMID:
30136914
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 nanoparticle may suppress the expression of VEGF, MMP-9 and HIF-1α in Lewis lung cancer mice.
Jun 17, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Beijing Da Xue Xue Bao Yi Xue Ban. 2016 Jun 18 ;48(3):496-501. PMID:
27318914
Article Published Date
: Jun 17, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Lung Cancer
Pharmacological Actions
:
Antiproliferative
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Grape juice concentrate protects rat liver against cadmium intoxication.
Jun 30, 2016
Click here to read the entire abstract
Pubmed Data
: Drug Res (Stuttg). 2016 Jul ;66(7):339-44. Epub 2016 Apr 7. PMID:
27056637
Article Published Date
: Jun 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Grape
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
Problem Substances
:
Cadmium
[+]
Grape seed extracts may improve the quality of life of lung fibrosis patients by inhibiting MMP-9 and TGF-β1 expression in the lungs.
Mar 11, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2017 Mar 12 ;273:1-9. Epub 2017 Mar 12. PMID:
28300665
Article Published Date
: Mar 11, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Grape Seed Extract
Diseases
:
Pulmonary Fibrosis: Bleomycin-Induced
Pharmacological Actions
:
Anti-Fibrotic
,
Chemoprotective Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Hibiscus sabdariffa extract led to the reduced invasiveness of prostate cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 ;7(7):5065-87. Epub 2015 Jun 24. PMID:
26115086
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Hibiscus sabdariffa
Diseases
:
Prostate Cancer
,
Prostate Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Hydrogen improves neurological function through attenuation of blood-brain barrier disruption in spontaneously hypertensive stroke-prone rats.
Apr 19, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Neurosci. 2015 Apr 20 ;16:22. Epub 2015 Apr 20. PMID:
25925889
Article Published Date
: Apr 19, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Hypertension
,
Oxidative Stress
,
Stroke: Attenuation/Recovery
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Hyperbaric oxygen therapy could inhibit glioma cell proliferation and inflammatory cell infiltration.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Med. 2016 Nov ;5(11):3147-3155. Epub 2016 Oct 13. PMID:
27734611
Article Published Date
: Oct 31, 2016
Study Type
: Transgenic Animal Study
Additional Links
Diseases
:
Glioma
Therapeutic Actions
:
Hyperbaric Treatment
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Chemosensitizer
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
I. obliquus can prevent the aging process by attenuating oxidative stress in a model of stress-induced premature senescence.
Apr 30, 2011
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Cells. 2011 May ;31(5):423-9. Epub 2011 Feb 22. PMID:
21359681
Article Published Date
: Apr 30, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Chaga Mushroom (Inonotus obliquus)
Diseases
:
Aging Skin
,
Lipid Peroxidation
,
Oxidative Stress
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Cytoprotective
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Inhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Sci Rep. 2016 ;6:21731. Epub 2016 Feb 25. PMID:
26911838
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
STAT3 Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Isoliquiritigenin suppresses the proliferation and induced apoptosis via miR-32/LATS2/Wnt in nasopharyngeal carcinoma.
Aug 04, 2019
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2019 Aug 5 ;856:172352. Epub 2019 Apr 17. PMID:
31004603
Article Published Date
: Aug 04, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
MicroRNA modulator
,
Wnt/β-catenin signaling pathway modulation
[+]
Kaempferol might act as a therapeutic potential candidate for cancer metastasis.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Biochem Cell Biol. 2015 Feb ;93(1):16-27. Epub 2014 Sep 12. PMID:
25453494
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Kaempferol
Diseases
:
Breast Cancer: Triple Negative
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Korean Red Ginseng extracts might have the ability to reduce the incidence of leukemia.
Sep 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Ginseng Res. 2016 Oct ;40(4):431-436. Epub 2016 Aug 4. PMID:
27746697
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Lymphoma
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Caspase-3 Activation
,
Caspase-8 activation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Liquiritigenin potentiates the inhibitory effects of cisplatin on invasion and metastasis in B16F10 melanoma cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(5):761-70. Epub 2015 May 15. PMID:
25978595
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Liquiritigenin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Chemotherapeutic Synergy: Cisplatin
[+]
Low molecular-weight fucoidan can be used as a skin-protective remedy for photoaging.
Aug 17, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mar Drugs. 2018 Aug 18 ;16(8). Epub 2018 Aug 18. PMID:
30126169
Article Published Date
: Aug 17, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Luteolin can be a chemotherapeutic agent against colorectal cancer.
Oct 31, 2014
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2014 Nov ;33(11):1176-85. Epub 2014 Feb 14. PMID:
24532706
Article Published Date
: Oct 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Luteolin
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Luteolin inhibits proliferation and induces apoptosis of human melanoma cells.
Jan 20, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jan 21. Epub 2019 Jan 21. PMID:
30663726
Article Published Date
: Jan 20, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Luteolin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Mangiferin reduces colonic damage in a murine model of colitis.
Jun 24, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Jun 25 ;253:18-26. Epub 2016 Apr 26. PMID:
27125760
Article Published Date
: Jun 24, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Mangiferin
Diseases
:
Colitis
,
Inflammatory Bowel Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Melatonin has cardioprotective effects in a rat model of cardiorenal syndrome.
Jul 27, 2016
Click here to read the entire abstract
Pubmed Data
: J Pineal Res. 2016 Jul 28. Epub 2016 Jul 28. PMID:
27465663
Article Published Date
: Jul 27, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Melatonin
Diseases
:
Heart Disease
,
Kidney Diseases
,
Multi-Organ Failure
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Metformin in combination with curcumin inhibits the growth, metastasis and angiogenesis of hepatocellular carcinoma.
Aug 18, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Carcinog. 2017 Aug 19. Epub 2017 Aug 19. PMID:
28833603
Article Published Date
: Aug 18, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Curcumin
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
[+]
Modulation of antioxidant potential with coenzyme Q10 suppressed invasion of temozolomide-resistant glioma.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2019 ;2019:3061607. Epub 2019 Mar 12. PMID:
30984333
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Coenzyme Q10
Diseases
:
Cancers: Drug Resistant
,
Glioblastoma
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Chemotherapeutic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Myricetin has potential anticancer activity and could be an important chemoprevention agent for bladder cancer.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2012 ;64(4):599-606. Epub 2012 Apr 6. PMID:
22482362
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Myricetin
Diseases
:
Bladder Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
NAC reduces hippocampal neuronal damage following transient global ischemia.
Nov 09, 2019
Click here to read the entire abstract
Pubmed Data
: Brain Res Bull. 2019 Nov 10. Epub 2019 Nov 10. PMID:
31722253
Article Published Date
: Nov 09, 2019
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Naringenin inhibits UVB irradiation-induced skin damage and may be a promising therapeutic approach to control skin disease.
Jul 23, 2015
Click here to read the entire abstract
Pubmed Data
: J Nat Prod. 2015 Jul 24 ;78(7):1647-55. Epub 2015 Jul 8. PMID:
26154512
Article Published Date
: Jul 23, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Naringenin
Diseases
:
Inflammation
,
Skin Cancer
,
Skin Cancer: Prevention
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anticarcinogenic Agents
,
Antioxidants
,
Interferon Gamma Reducer
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Cytokines
[+]
Naringin may be a promising agent for the treatment of physical fatigue.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharm Biol. 2017 Dec ;55(1):423-427. PMID:
27937032
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Citrus naringin
Diseases
:
Fatigue
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Naturally fermented Noni juice manifests a protective potential on liver fibrosis.
Mar 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Chin Med Assoc. 2017 Apr ;80(4):212-221. Epub 2017 Mar 6. PMID:
28268174
Article Published Date
: Mar 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Noni
Diseases
:
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Neuroprotective effect of berberine agonist against impairment of learning and memory skills in severe traumatic brain injury.
Mar 04, 2018
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2018 Mar 5. Epub 2018 Mar 5. PMID:
29512719
Article Published Date
: Mar 04, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Traumatic Brain Injury
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Nobiletin ameliorates the cardiovascular dysfunction of diabetes by inhibiting oxidative stress, MMP-2 and MMP-9.
Jul 12, 2016
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2016 Jul 13 ;7(7):3121-9. PMID:
27279123
Article Published Date
: Jul 12, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Nobiletin
Diseases
:
Cardiovascular Diseases
,
Diabetic Complications
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Oleanolic acid exerts inhibitory effects on the late stage of osteoclastogenesis and prevents bone loss in osteoprotegerin knockout mice.
Jul 17, 2019
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2019 Jul 18. Epub 2019 Jul 18. PMID:
31318102
Article Published Date
: Jul 17, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Oleanolic acid
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Osteoprotective
[+]
Oral administration of black ginger extract significantly prevents UVB-induced photoaging in hairless mice.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Photodermatol Photoimmunol Photomed. 2014 Oct ;30(5):237-45. Epub 2014 Jan 9. PMID:
24313661
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Kaempferia parviflora
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Catalase Up-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Photoprotective
Additional Keywords
:
Plant Extracts
[+]
Oral Aloe vera gel powder has the ability to prevent the skin photoaging.
Apr 03, 2016
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2016 Apr 4:1-9. Epub 2016 Apr 4. PMID:
27045316
Article Published Date
: Apr 03, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
Paeoniflorin attenuates postoperative pain by suppressing matrix metalloproteinase-9/2 in mice.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Pain. 2018 02 ;22(2):272-281. Epub 2017 Oct 29. PMID:
29081070
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Allodynia
,
Hyperalgesia
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Paeonol exerts anti-angiogenic and anti-metastatic activities.
Jun 30, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2009 Jul ;32(7):1142-7. PMID:
19571375
Article Published Date
: Jun 30, 2009
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Paeonol
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-Angiogenic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Palmitoylethanolamide and polydatin treatment causes endometriotic lesion regression.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:382. Epub 2016 Oct 14. PMID:
27790149
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Palmitoylethanolamide
Diseases
:
Endometriosis
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells.
Oct 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Death Dis. 2013 Oct 31 ;4:e891. Epub 2013 Oct 31. PMID:
24176849
Article Published Date
: Oct 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Parthenolide
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Autophagy Up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Piperlongumine suppresses growth and sensitizes pancreatic tumors to gemcitabine in a xenograft mouse model.
Dec 13, 2015
Click here to read the entire abstract
Pubmed Data
: Cancer Prev Res (Phila). 2015 Dec 14. Epub 2015 Dec 14. PMID:
26667450
Article Published Date
: Dec 13, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Long Pepper
Diseases
:
Pancreatic Cancer
Pharmacological Actions
:
Antiproliferative
,
Bcl-2 protein down-regulation
,
Chemosensitizer
,
Cyclin D1 Down-Regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Survivin Down-Regulation
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Chemotherapeutic Synergy: Gemcitabine
[+]
Propolis enhances cutaneous wound healing by promoting TGF-Beta/Smad-mediated collagen production in a streptozotocin-induced type I diabetic mouse model.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2015;37(3):940-954. Epub 2015 Sep 18. PMID:
26381245
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Bee
Diseases
:
Diabetes Mellitus: Type 1
,
Wound Healing
Pharmacological Actions
:
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Protective effects of paeoniflorin on alveolar bone resorption and soft-tissue breakdown in experimental periodontitis.
Mar 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Periodontal Res. 2016 Apr ;51(2):257-64. Epub 2015 Jul 14. PMID:
26179445
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Paeoniflorin
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Protective role of black tea flavonoids against ethanol-induced gastropathy via matrix metalloproteinase pathway.
Sep 30, 2019
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2019 Oct ;34(4):379-394. Epub 2018 Aug 23. PMID:
31686725
Article Published Date
: Sep 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
,
Flavonoids
Diseases
:
Alcohol Toxicity
,
Gastrointestinal Diseases
Pharmacological Actions
:
Gastroprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Quercetin has a certain therapeutic effect on rats with diabetic retinopathy.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2017 Dec ;14(6):6022-6026. Epub 2017 Oct 10. PMID:
29285153
Article Published Date
: Nov 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Diabetic Retinopathy
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Quercetin reduces oxidative stress and inhibits activation of c Jun N terminal kinase/activator protein 1 signalling.
Jan 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2014 Feb ;9(2):435-42. Epub 2013 Dec 6. PMID:
24337353
Article Published Date
: Jan 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Aneurysm: Aortic
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Regular boysenberry consumption has the potential to moderate chronic lung remodelling and fibrosis in asthma and other chronic pulmonary diseases.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Lung Cell Mol Physiol. 2016 Sep 1 ;311(3):L628-38. Epub 2016 Jul 1. PMID:
27371734
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Berries: All
Diseases
:
Asthma
,
Fibrosis
,
Lung Diseases
Pharmacological Actions
:
Anti-Fibrotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development.
Nov 30, 2011
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2011 Dec ;171(2):e237-46. Epub 2011 Aug 24. PMID:
21962734
Article Published Date
: Nov 30, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Resveratrol downregulates the TLR4 signaling pathway to reduce brain damage in a rat model of focal cerebral ischemia.
Mar 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2019 Apr ;17(4):3215-3221. Epub 2019 Feb 27. PMID:
30936996
Article Published Date
: Mar 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Resveratrol reduces hippocampal neuronal cell damage following transient global ischemia by reducing MMP-9 activity.
Sep 02, 2015
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2015 Sep 3. Epub 2015 Sep 3. PMID:
26421359
Article Published Date
: Sep 02, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Resveratrol
Diseases
:
Cerebral Ischemia
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Saffron aqueous extract exerted dose-dependent anti-atherosclerotic and plaque-stabilizing effects in mice.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2017 Nov 1. Epub 2017 Nov 1. PMID:
29128090
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-atherogenic
,
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Salvianolic acid C significantly ameliorated the progression of aortic aneurysm in mice.
Nov 30, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Dec 1 ;166:75-81. Epub 2016 Sep 20. PMID:
27663582
Article Published Date
: Nov 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Polyphenols
,
Red Sage
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sea buckthorn has potential as a protective and therapeutic treatment candidate against skin aging.
Jul 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2012 Aug ;30(2):392-400. Epub 2012 May 24. PMID:
22641502
Article Published Date
: Jul 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Sea buckthorn
Diseases
:
Aging Skin
,
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Sea cucumber extract TBL-12 could suppress the proliferation and metastasis of human prostate cancer cells.
Mar 18, 2019
Click here to read the entire abstract
Pubmed Data
: Prostate. 2019 Mar 19. Epub 2019 Mar 19. PMID:
30889629
Article Published Date
: Mar 18, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Sea Cucumber
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Selective cytotoxicity of the herbal substance acteoside against tumor cells and its mechanistic insights.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2018 06 ;16:169-178. Epub 2018 Mar 1. PMID:
29505920
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
Immunomodulatory
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Selective Cytotoxicity
[+]
Sesamol attenuates experimentally induced myocardial infarction.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: Cell Physiol Biochem. 2011 ;27(3-4):273-80. Epub 2011 Apr 1. PMID:
21471716
Article Published Date
: Jan 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Sesamol
Diseases
:
Hypertension
,
Myocardial Infarction
Pharmacological Actions
:
Antioxidants
,
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sesamol attenuates monocrotaline-induced sinusoidal obstruction syndrome.
Jun 17, 2011
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Biophys. 2011 Jun 17. Epub 2011 Jun 17. PMID:
21681587
Article Published Date
: Jun 17, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Sesamol
Diseases
:
Sinusoidal obstruction syndrome
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Sulforaphane may be a potential a candidate for use in the treatment of acute lung injury.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2016 Jan ;37(1):182-8. Epub 2015 Oct 27. PMID:
26531002
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-E2-Related Factor-2 (Nrf2) Modulator
,
Prostaglandin PGE2 downregulation
[+]
Sulforaphane reduces inflammation following spinal cord injury in mice.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Ann Clin Lab Sci. 2010;40(4):354-60. PMID:
20947810
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Sulforaphane
Diseases
:
Spinal Cord Injuries
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Supplementation with lycopene-enriched tomato extract may counteract hepatocellular carcinoma progression or protect against disease onset.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 Nov-Dec;67(8):1268-75. Epub 2015 Oct 16. PMID:
26474105
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Lycopene
,
Tomato
Diseases
:
Liver Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Anticarcinogenic Agents
,
Chemopreventive
,
Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Synthetic cannabinoids inhibited growth, migration and invasion of NSCLC cells in in vitro as well as in vivo in a mouse model.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancer Prev Res (Phila). 2011 Jan ;4(1):65-75. Epub 2010 Nov 19. PMID:
21097714
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cannabinoids: Synthetic
Diseases
:
Carcinoma: Non-Small-Cell Lung
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Cannabinoid Receptors
[+]
Tanshinone IIA attenuates the development of elastase-induced experimental abdominal aortic aneurysms.
Sep 30, 2012
Click here to read the entire abstract
Pubmed Data
: Zhonghua Wai Ke Za Zhi. 2012 Oct ;50(10):923-7. PMID:
23302465
Article Published Date
: Sep 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Tetramethylpyrazine may be a potential candidate for neuropathic pain treatment.
Aug 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Neuroinflammation. 2017 Aug 31 ;14(1):174. Epub 2017 Aug 31. PMID:
28859670
Article Published Date
: Aug 30, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ligustrazine
Diseases
:
Neuropathic Pain
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vasodilator Agents
[+]
The combination of CS plus metronomic ZOL demonstrated significant antitumor, anti-metastatic and anti-osteolytic effects against breast cancer
May 19, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 May 20. Epub 2015 May 20. PMID:
25998578
Article Published Date
: May 19, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Green Tea
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Natural Substance/Drug Synergy
Problem Substances
:
Zoledronic Acid
[+]
The dietary ingestion of Aloe sterols protected against chronic UVB damage in mouse skin.
Dec 19, 2016
Click here to read the entire abstract
Pubmed Data
: Photodermatol Photoimmunol Photomed. 2016 Dec 20. Epub 2016 Dec 20. PMID:
27995657
Article Published Date
: Dec 19, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Aloe Vera
Diseases
:
Ultraviolet Radiation Induced Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Aloe vera
,
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Ultraviolet Radiation Induced Damage
[+]
The main components of pomegranate can inhibit metastasis of ovarian cancer.
Nov 26, 2017
Click here to read the entire abstract
Pubmed Data
: Cancer Biol Ther. 2017 Nov 27:1-10. Epub 2017 Nov 27. PMID:
29173024
Article Published Date
: Nov 26, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Ellagic Acid
,
Luteolin
,
Pomegranate
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Theaflavins have therapeutic potential in the treatment of periodontal disease.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Periodontal Res. 2018 Dec ;53(6):1009-1019. Epub 2018 Aug 30. PMID:
30159985
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Theaflavins
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-6 Downregulation
,
Interleukin-8 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These data indicate that quercetin may be useful for the prevention and treatment of abdominal aortic aneurysms.
Sep 04, 2012
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2012 Sep 5 ;690(1-3):133-41. Epub 2012 Jun 19. PMID:
22728078
Article Published Date
: Sep 04, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Quercetin
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings represent the promising anti-schistosomal activities of probiotics and yogurt.
Jan 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2019 Jan 3 ;19(1):3. Epub 2019 Jan 3. PMID:
30606163
Article Published Date
: Jan 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Probiotics
,
Yoghurt
Diseases
:
Lipid Peroxidation
,
Liver Cirrhosis
,
Oxidative Stress
,
Schistosomiasis
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings reveal a new potential therapeutic application of curcumin in anti-metastatic therapy for endometrial carcinoma.
Aug 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2015 Sep ;10(3):1297-1302. Epub 2015 Jul 9. PMID:
26622667
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These findings show that baicalein is an effective agent for abdominal aortic aneurysm prevention.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Sci China Life Sci. 2016 Sep ;59(9):940-9. Epub 2016 Jun 22. PMID:
27333787
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Baicalein
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These results demonstrate a novel role of eicosapentaenoic acid in attenuating abdominal aortic aneurysm formation.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2014 ;9(5):e96286. Epub 2014 May 5. PMID:
24798452
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
EPA (Eicosapentaenoic Acid)
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
These results demonstrated that salvianolic acid A held great potential for aortic aneurysm therapy.
Sep 14, 2014
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2014 Sep 15 ;21(10):1137-45. Epub 2014 Jun 7. PMID:
24916705
Article Published Date
: Sep 14, 2014
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Red Sage
Diseases
:
Aortic Aneurysm
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Superiority of Natural Substances versus Drugs
[+]
These results suggest a potential therapeutic role of isoliquiritigenin to treat osteoarthritis.
Jun 14, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Ther Methods Clin Dev. 2018 Jun 15 ;9:153-159. Epub 2018 Feb 15. PMID:
29766025
Article Published Date
: Jun 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
These results suggest that piperine free P. nigrum extracts can enhance breast cancer cell response to phytochemicals.
May 03, 2016
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2016 May 4. Epub 2016 May 4. PMID:
27155135
Article Published Date
: May 03, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Black Pepper
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Suppressor Protein p53 Upregulation
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Bioenhancer
,
Natural Substance Synergy
[+]
These results suggest that treatment with EGb 761 in mice prevented the development of CaCl2-induced abdominal aortic aneurysm.
Oct 27, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Oct 28 ;150(1):308-15. Epub 2013 Sep 5. PMID:
24012526
Article Published Date
: Oct 27, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Ginkgo biloba
Diseases
:
Aneurysm: Aortic
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
This study demonstrated tanshinone IIA suppressed the progression of atherosclerosis.
Apr 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Open. 2017 Apr 15 ;6(4):489-495. Epub 2017 Apr 15. PMID:
28412716
Article Published Date
: Apr 14, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Atherosclerosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
This study provides evidence for the beneficial effects of far-infrared therapy exposure in a model of skin photoaging.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2017 ;12(3):e0174042. Epub 2017 Mar 16. PMID:
28301572
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Ultraviolet Radiation Induced Damage
Therapeutic Actions
:
Thermal Therapy: Far-Infrared
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Photoprotective
[+]
This study provides evidence that morin may have anticancer effects against metastatic breast cancer.
Sep 30, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2014 Oct ;45(4):1629-37. Epub 2014 Jul 4. PMID:
24993541
Article Published Date
: Sep 30, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Fig
,
Flavonoids
,
Mulberry
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
This study shows asiatic acid is effective against multiple models of focal ischemia.
May 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Stroke. 2012 Jun ;43(6):1632-8. Epub 2012 Apr 17. PMID:
22511009
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Asiatic Acid
Diseases
:
Stroke
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Thuja orientalis reduces airway inflammation in ovalbumin-induced allergic asthma.
Aug 31, 2015
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2015 Sep ;12(3):4640-4646. Epub 2015 Jun 11. PMID:
26063078
Article Published Date
: Aug 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Thuja
Diseases
:
Asthma
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
interleukin-13 down-regulation
,
Interleukin-4 downregulation
,
Interleukin-5 downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Total saponins from Rosa laevigata can be applied as one effective candidate for the treatment of liver fibrosis.
Jun 14, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2015 Jun 15 ;7(6):4829-50. Epub 2015 Jun 15. PMID:
26083117
Article Published Date
: Jun 14, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Triptolide inhibited B16F10 cell migration and invasion via the inhibition of NF-κB expression
Sep 28, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2015 Sep 29. Epub 2015 Sep 29. PMID:
26420756
Article Published Date
: Sep 28, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Triptolide
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Ursolic acid ameliorated the severity of abdominal aortic aneurysms.
Feb 14, 2018
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2018 Feb 15 ;271:128-135. Epub 2018 Feb 15. PMID:
29499360
Article Published Date
: Feb 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Ursolic Acid
Diseases
:
Aortic Aneurysm
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Verbascoside has potential use as a potent anticancer agent in oral squamous cell carcinoma therapeutic strategies.
Aug 14, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2018 Aug 15 ;143(4):980-991. Epub 2018 Apr 16. PMID:
29536537
Article Published Date
: Aug 14, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Natural Substances Versus Drugs
[+]
Vitamin C in combination with vitamin K3 inhibits primary tumor growth and exhibits antimetastastic potential in vivo through attenuated tumor invasion and proliferation.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2011 ;63(7):1036-43. Epub 2011 Sep 2. PMID:
21888506
Article Published Date
: Dec 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin C
,
Vitamin K
Diseases
:
Lung Cancer
,
Lung Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Disease Regression
,
Dose Response
[+]
Vitamin E has a potential role as an atheroprotective agent in early and established atherosclerosis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Nutr Res. 2016 ;60:31525. Epub 2016 Oct 28. PMID:
27799085
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E: alpha tocopherol
,
Vitamin E: Gamma-tocotrienol
Diseases
:
Atherosclerosis
,
Cardiovascular Diseases
,
Coronary Artery Disease
Pharmacological Actions
:
Anti-atherogenic
,
Cardioprotective
,
Matrix Metalloproteinase-12 (MMP-12) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Risk Reduction
[+]
Zerumbone suppresses the motility and tumorigenecity of triple negative breast cancer cells.
Jan 11, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jan 12 ;7(2):1544-58. PMID:
26637807
Article Published Date
: Jan 11, 2016
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Zerumbone
Diseases
:
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.
Jul 25, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Jul 26 ;7(30):47232-47241. PMID:
27323807
Article Published Date
: Jul 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Polyphenols
Diseases
:
Cancers: All
Pharmacological Actions
:
angiogenesis
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
β-Carotene is a potent anti-inflammatory agent that improves the barrier functions of atopic dermatitis skin.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Exp Dermatol. 2019 Sep ;28(9):1044-1050. Epub 2019 Aug 8. PMID:
31287602
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
beta-Carotene
Diseases
:
Atopic Dermatitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-4 downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Theaflavins suppress the growth and metastasis of human hepatocellular carcinoma.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2016 ;9:4265-75. Epub 2016 Jul 14. PMID:
27478384
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Theaflavins
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
"Resveratrol inhibits tumor necrosis factor-alpha-mediated matrix metalloproteinase-9 expression and invasion of human hepatocellular carcinoma cells."
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2008 Jul-Aug;62(6):366-72. Epub 2007 Oct 22. PMID:
17988825
Article Published Date
: Jul 01, 2008
Study Type
: In Vitro Study
Additional Links
Substances
:
Resveratrol
,
Stilbenes
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
2,3,5,4 tetrahydroxy diphenylethylene 2 O glucoside inhibits the adhesion and invasion of A549 human lung cancer cells.
Nov 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2017 Dec ;16(6):8900-8906. Epub 2017 Oct 2. PMID:
28990072
Article Published Date
: Nov 30, 2017
Study Type
: In Vitro Study
Additional Links
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
6-Shogaol, an active constituent of ginger, inhibits breast cancer cell invasion.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Br J Pharmacol. 2010 Dec ;161(8):1763-77. PMID:
20718733
Article Published Date
: Dec 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
6-Shogaol
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
A combination of Citrus reticulata peel and black tea inhibits migration and invasion of liver cancer.
Oct 29, 2019
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2019 Oct 30. Epub 2019 Oct 30. PMID:
31673889
Article Published Date
: Oct 29, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Black Tea
,
Citrus Peel
,
Orange: Mandarin
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
A novel function of artesunate on inhibiting migration and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients.
Jun 23, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Arthritis Res Ther. 2019 Jun 24 ;21(1):153. Epub 2019 Jun 24. PMID:
31234900
Article Published Date
: Jun 23, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Artesunate
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
A review of formononetin and its anticancer potentials and mechanisms.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2019 ;10:820. Epub 2019 Jul 26. PMID:
31402861
Article Published Date
: Dec 31, 2018
Study Type
: Review
Additional Links
Substances
:
Formononetin
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Chemopreventive
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
A Rheum palmatum extract has potential anti-metastatic activity.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2015 Jul ;40(1):30-8. Epub 2015 May 16. PMID:
26056975
Article Published Date
: Jun 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Rhubarb
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
,
Plant Extracts
[+]
A water extract of Rosa hybrida has the potential to act as a novel agent for the prevention and treatment of vascular diseases.
Feb 24, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Mol Med. 2016 Feb 25. Epub 2016 Feb 25. PMID:
26935151
Article Published Date
: Feb 24, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Rose
Diseases
:
Cardiovascular Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
P21 Activation
[+]
A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects.
Mar 02, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Mar 3 ;7:43789. Epub 2017 Mar 3. PMID:
28256567
Article Published Date
: Mar 02, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Wogonin
Diseases
:
Osteoarthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Chondroprotective
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Achillea fragrantissima possesses anti-neuroinflammatory activities for prevention or treatment of neurodegenerative diseases.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2011 ;11:98. Epub 2011 Oct 21. PMID:
22018032
Article Published Date
: Dec 31, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Achillea fragrantissima
Diseases
:
Brain: Microglial Activation
,
Brain Inflammation
,
Neurodegenerative Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
,
Nitric Oxide Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Acteoside has the potential to be a potent anticancer agent in therapeutic strategies for fibrosarcoma metastasis.
Apr 30, 2011
Click here to read the entire abstract
Pubmed Data
: Mol Nutr Food Res. 2011 May ;55 Suppl 1:S103-16. Epub 2010 Nov 18. PMID:
21089054
Article Published Date
: Apr 30, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Fibrosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Allicin may be recognized as an anti-invasive agent for lung adenocarcinoma treatment.
Jun 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Jul ;14(1):468-474. Epub 2017 May 5. PMID:
28693193
Article Published Date
: Jun 30, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Allicin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
An alkaloid rich fraction from Nelumbo nucifera targets VSMC proliferation and migration to attenuate neo-intima formation.
Mar 20, 2016
Click here to read the entire abstract
Pubmed Data
: Atherosclerosis. 2016 Mar 21 ;248:179-189. Epub 2016 Mar 21. PMID:
27018542
Article Published Date
: Mar 20, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Atherosclerosis
,
Restenosis
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An ethanol extract of root of Prunus persica inhibited the growth of liver cancer cells.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2017 ;2017:8231936. Epub 2017 Oct 12. PMID:
29234432
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Peach
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of holy basil significantly inhibited cell adhesion and invasion at nontoxic concentrations.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2014 ;14:419. Epub 2014 Oct 27. PMID:
25345853
Article Published Date
: Dec 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Holy Basil
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
PI3K/Akt/signaling suppression
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
An extract of Lotus may be a powerful agent against colon cancer cells.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Mar ;13(3):1470-1478. Epub 2016 Dec 28. PMID:
28454279
Article Published Date
: Feb 28, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Lotus
Diseases
:
Colon Cancer
Pharmacological Actions
:
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Apoptotic
,
Bcl-2 protein down-regulation
,
COLON CANCER
,
Lotus
,
Plant Extracts
[+]
An extract of Z. cassumunar and its constituent should be benefit to ameliorate inflammation and hypersensitiveness of airway epithelium.
Feb 28, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Allergy Immunol. 2015 Mar ;33(1):42-51. PMID:
25840633
Article Published Date
: Feb 28, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginger
Diseases
:
Allergic Airway Diseases
,
Allergies
,
Hypersensitivity: Respiratory
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Enzyme Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins from black rice could suppress CAL 27 cell metastasis by reduction of MMP-2, MMP-9, and NF-κB p65 expression.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2015 ;67(2):327-38. Epub 2015 Feb 6. PMID:
25658905
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Rice: Black
Diseases
:
Oral Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.
Mar 31, 2019
Click here to read the entire abstract
Pubmed Data
: Cytokine. 2019 Apr ;116:48-60. Epub 2019 Jan 24. PMID:
30685603
Article Published Date
: Mar 31, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Quercetin
Diseases
:
Inflammation
,
Retinal Diseases
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2.
Jan 31, 2013
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharmacol. 2013 Feb ;65(2):310-6. Epub 2012 Oct 22. PMID:
23278699
Article Published Date
: Jan 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Antioxidative, anti-inflammatory, and matrix metalloproteinase inhibitory activities of 20(S)-ginsenoside Rg3 in cultured mammalian cell lines.
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Mol Biol Rep. 2013 Jan ;40(1):269-79. Epub 2012 Oct 10. PMID:
23054007
Article Published Date
: Dec 31, 2012
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Anti‑wrinkle effect of fermented black ginseng on human fibroblasts.
Feb 28, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Med. 2017 Mar ;39(3):681-686. Epub 2017 Jan 16. PMID:
28098856
Article Published Date
: Feb 28, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginseng
Diseases
:
Aging Skin
,
Wrinkles
Pharmacological Actions
:
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Apigenin is a new inhibitor of Akt in lung cancer and a potential natural compound for cancer chemoprevention.
Apr 27, 2017
Click here to read the entire abstract
Pubmed Data
: . PMID:
28125432
Article Published Date
: Apr 27, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Apigenin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Apple and Hop-polyphenols inhibit P. gingivalis-mediated precursor of MMP-9 activation and invasion of oral squamous cell carcinoma cells.
May 12, 2016
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2016 May 13:1-21. Epub 2016 May 13. PMID:
27177287
Article Published Date
: May 12, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Apple Polyphenols
,
Hops
Diseases
:
Oral Cancer
,
Periodontal Diseases
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Aqueous extracts of Toona sinensis leaves inhibit renal carcinoma cell growth and migration.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 2016 May-Jun;68(4):654-66. Epub 2016 Apr 26. PMID:
27115866
Article Published Date
: Apr 30, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Toona sinensis
Diseases
:
Kidney Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Cell cycle arrest
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Arctigenin significantly inhibited the migration and invasion of MDA-MB-231 cells.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Jan ;37(1):179-184. Epub 2016 Nov 23. PMID:
27878294
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Burdock
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Aromatic-turmerone attenuates invasion and expression of MMP-9 and COX-2 through inhibition of NF-κB activation in TPA-induced breast cancer cells.
Nov 30, 2012
Click here to read the entire abstract
Pubmed Data
: J Cell Biochem. 2012 Dec ;113(12):3653-62. PMID:
22740037
Article Published Date
: Nov 30, 2012
Study Type
: In Vitro Study
Additional Links
Substances
:
Turmerones
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Astragaloside IV inhibits breast cancer cell invasion.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Jan ;42:195-202. Epub 2016 Dec 5. PMID:
27930970
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
,
Cancer Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Astragaloside IV inhibits progression of glioma cancer cells.
Sep 08, 2017
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2017 Sep 9 ;491(1):98-103. Epub 2017 Jul 11. PMID:
28709870
Article Published Date
: Sep 08, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Astragaloside
Diseases
:
Glioma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
B. serrata extract inhibits proliferation, angiogenesis and migration and induces apoptosis in HT-29 cells
May 23, 2017
Click here to read the entire abstract
Pubmed Data
: Prostaglandins Other Lipid Mediat. 2017 May 24 ;131:1-8. Epub 2017 May 24. PMID:
28549801
Article Published Date
: May 23, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Frankincense
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Plant Extracts
[+]
Baicalein inhibits gastric cancer cell invasion and metastasis by reducing cell motility and migration via suppression of the p38 signaling pathway.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Feb ;33(2):737-43. Epub 2014 Dec 11. PMID:
25502212
Article Published Date
: Jan 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Baicalein is a potential novel therapeutic agent for patients with colorectal cancer.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2016 Jan ;11(1):685-688. Epub 2015 Nov 17. PMID:
26870267
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Baicalein may be developed as a potential, novel anticancer treatment for tumors.
Oct 08, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2016 Oct 9 ;17(10). Epub 2016 Aug 9. PMID:
27735841
Article Published Date
: Oct 08, 2016
Study Type
: Review
Additional Links
Substances
:
Baicalein
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Baicalein significantly attenuated E2-induced invasion of MCF-7 breast cancer cells.
Jul 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncol Lett. 2017 Aug ;14(2):1823-1830. Epub 2017 Jun 2. PMID:
28789417
Article Published Date
: Jul 31, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Baicalein suppresses colorectal carcinoma cell invasion.
Mar 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Apr ;37(4):2317-2323. Epub 2017 Feb 10. PMID:
28259937
Article Published Date
: Mar 31, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Baicalin has the potential to be used in novel anti cancer therapeutic formulations for treatment of ovarian cancer.
Oct 09, 2017
Click here to read the entire abstract
Pubmed Data
: Mol Med Rep. 2017 Oct 10. Epub 2017 Oct 10. PMID:
29039573
Article Published Date
: Oct 09, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Baicalein
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Benzyl-isothiocyanate induces apoptosis and inhibits migration and invasion of hepatocellular carcinoma cells in vitro.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Cancer. 2017 ;8(2):240-248. Epub 2017 Jan 15. PMID:
28243328
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Benzyl isothiocyanate
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Survivin Down-Regulation
[+]
Berberine has potential as an anti-metastatic agent in melanoma.
Aug 12, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2018 Aug 13 ;23(8). Epub 2018 Aug 13. PMID:
30104528
Article Published Date
: Aug 12, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Berberine may have potential applications as a chemotherapeutic agent for the management of head and neck squamous carcinoma.
Sep 24, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Sep 25. Epub 2015 Sep 25. PMID:
26503508
Article Published Date
: Sep 24, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Head and Neck Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Beta-elemene inhibits tumor growth by downregulating the expression of uPA, uPAR, MMP-2, and MMP-9.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Melanoma Res. 2015 Feb ;25(1):15-21. PMID:
25405459
Article Published Date
: Jan 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Beta-Elemene
Diseases
:
Cancer Metastasis
,
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Bi-directional solid fermentation may enhance the efficacy of Huaier in MDA-MB-231 cells.
Mar 14, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Chin Med Assoc. 2018 Mar 15. Epub 2018 Mar 15. PMID:
29551488
Article Published Date
: Mar 14, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Biochanin-A induces apoptosis and suppresses migration in FaDu human pharynx squamous carcinoma cells.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Nov ;38(5):2985-2992. Epub 2017 Sep 13. PMID:
28901495
Article Published Date
: Oct 31, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Head and Neck Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Bcl-xL down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Bisdemethoxycurcumin may have potential as a novel anti-metastasis agent for the treatment of human cervical cancer.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Anticancer Res. 2018 Jul ;38(7):3989-3997. PMID:
29970522
Article Published Date
: Jun 30, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Cancer Metastasis
,
Cervical Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Bisdemethoxycurcumin serves as a therapeutic medicine to suppress ovarian cancer.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:28773. Epub 2016 Jun 28. PMID:
27349797
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Bisdemethoxycurcumin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antioxidants
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Dose Response
[+]
Black tea theaflavins represent promising multifunctional therapeutic agents for prevention and treatment of periodontal disease.
Aug 22, 2016
Click here to read the entire abstract
Pubmed Data
: J Periodontal Res. 2016 Aug 23. Epub 2016 Aug 23. PMID:
27549582
Article Published Date
: Aug 22, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Black Tea
,
Theaflavins
Diseases
:
Periodontal Diseases
,
Porphyromonas gingivalis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-8 (MMP-8) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Blackberry leaf extract contains phytonutrients that prevent wrinkle formation.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Cosmet Sci. 2007 Oct;29(5):411. PMID:
18489379
Article Published Date
: Oct 01, 2007
Study Type
: In Vitro Study
Additional Links
Substances
:
Blackberry
Diseases
:
Aging Skin
Pharmacological Actions
:
Interleukin-1 alpha downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Bromelain and papain have cytotoxic effects on human cholangiocarcinoma cell lines.
Apr 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2016 May ;48(5):2025-34. Epub 2016 Mar 1. PMID:
26935541
Article Published Date
: Apr 30, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Bromelain
,
Papain
Diseases
:
Cholangiocarcinoma
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cytotoxic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2015 Jan ;30(1):74-82. Epub 2013 Aug 16. PMID:
23949904
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Bufalin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
C. longa and curcumin might decrease the risk of cancer and other malignant diseases in the reproductive system.
Oct 25, 2017
Click here to read the entire abstract
Pubmed Data
: Endocr Regul. 2017 Oct 26 ;51(4):220-228. PMID:
29232190
Article Published Date
: Oct 25, 2017
Study Type
: Review
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Ovarian Cancer
,
Prostate Cancer
,
Testicular Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Prostaglandin PGE2 downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Cannabinoid receptor agonists, including WIN, may be considered as novel therapeutics for the treatment of hepatocellular carcinoma.
Nov 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2015 Dec ;12(6):7963-70. Epub 2015 Oct 23. PMID:
26500101
Article Published Date
: Nov 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Cannabinoids: Synthetic
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Cannabinoid Receptor Antagonist/Inverse Agonist
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Capsaicin plays a chemo-modulatory and anti-cancer role working against experimentally induced lung carcinogenesis.
May 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharmacopuncture. 2015 Jun ;18(2):19-25. PMID:
26120484
Article Published Date
: May 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Capsaicin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Chemopreventive
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Carnosine suppresses human colorectal cell migration and intravasation.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2019 ;47(2):477-494. PMID:
30909731
Article Published Date
: Dec 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Carnosine
Diseases
:
Cancer Metastasis
,
Colorectal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Carthamus tinctorius L may potentially serve as a cardio-protective agent against LPS- induced cardiac fibrosis.
Feb 28, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Mar ;32(3):754-763. Epub 2016 Apr 20. PMID:
27098997
Article Published Date
: Feb 28, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Safflower
Diseases
:
Fibrosis
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Cardioprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Carvacrol reduced tissue damage and bone loss caused by ligation-induced periodontitis.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: J Periodontol. 2017 07 ;88(7):e120-e128. Epub 2017 Apr 7. PMID:
28387609
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Periodontitis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Chrysanthemum indicum ethanolic extract inhibits invasion of hepatocellular carcinoma.
Jan 31, 2010
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2010 Feb ;23(2):413-21. PMID:
20043102
Article Published Date
: Jan 31, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Chrysin inhibits tumor promoter-induced MMP-9 expression in gastric cancer cells.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(4):e0124007. Epub 2015 Apr 15. PMID:
25875631
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Chrysin
Diseases
:
Gastric Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Co-treatment of tamoxifen and naringenin could inhibit cell proliferation more effectively in ER+ breast cancer cells.
Aug 24, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicology. 2018 Aug 25. Epub 2018 Aug 25. PMID:
30153467
Article Published Date
: Aug 24, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Naringenin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Synergy with Tamoxifen
[+]
Combined exosome-melatonin regimen was superior to either alone in protecting the liver against ischemia-reperfusion injury.
Dec 31, 2016
Click here to read the entire abstract
Pubmed Data
: Am J Transl Res. 2017 ;9(4):1543-1560. Epub 2017 Apr 15. PMID:
28469765
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Exosomes
[+]
Connectivity map identifies luteolin as a treatment option of ischemic stroke.
Mar 24, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Mol Med. 2019 Mar 25 ;51(3):37. Epub 2019 Mar 25. PMID:
30911000
Article Published Date
: Mar 24, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Luteolin
Pharmacological Actions
:
Anti-Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Neuroprotective Agents
[+]
Crocetin inhibits growth of colon cancer cells and prevents tube formation through induction of apoptosis.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Saudi J Biol Sci. 2018 Dec ;25(8):1767-1771. Epub 2017 Apr 17. PMID:
30591798
Article Published Date
: Nov 30, 2018
Study Type
: In Vitro Study
Additional Links
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Crude extracts of Rheum palmatum may be used as a novel anti-metastasis agents for the treatment of human colon cancer cells.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2015 Jul ;30(7):852-63. Epub 2014 Feb 4. PMID:
24497447
Article Published Date
: Jun 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Rhubarb
Diseases
:
Colon Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells.
Jun 30, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Ther Med. 2017 Jul ;14(1):805-812. Epub 2017 Jun 6. PMID:
28673003
Article Published Date
: Jun 30, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin has potential as a chemosensitizer for carboplatin in the treatment of patients with NSCLC.
Feb 24, 2015
Click here to read the entire abstract
Pubmed Data
: Exp Biol Med (Maywood). 2015 Feb 25. Epub 2015 Feb 25. PMID:
25716014
Article Published Date
: Feb 24, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Chemosensitizer
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Drug: Carboplatin
,
Natural Substance/Drug Synergy
[+]
Curcumin induces apoptosis and suppresses invasion in acute monocytic leukemia SHI-1 cells.
Jun 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2015 Jul 1:1-9. Epub 2015 Jul 1. PMID:
26134921
Article Published Date
: Jun 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Leukemia: Monocytic
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Curcumin inhibits cell proliferation and promotes apoptosis in osteoclastoma cell through suppression of MMP-9 and NF-κB, and activation JNK signaling pathways.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Clin Exp Pathol. 2015 ;8(6):6037-45. Epub 2015 Jun 1. PMID:
26261481
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Osteoclastoma
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Caspase-3 Activation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Curcumin inhibits cyclooxygenase and matrix metalloproteinase-8 expression associated with breast cancer progrression.
Nov 01, 2005
Click here to read the entire abstract
Pubmed Data
: Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1612-20. PMID:
16356124
Article Published Date
: Nov 01, 2005
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Curcumin inhibits inflammatory cytokines and MMP-9 in primary gingival epithelial cells stimulated with P. gingivalis-derived lipopolysaccharide.
May 12, 2019
Click here to read the entire abstract
Pubmed Data
: Odontology. 2019 May 13. Epub 2019 May 13. PMID:
31087163
Article Published Date
: May 12, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Porphyromonas gingivalis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin inhibits liver cancer cell invasiveness.
Oct 01, 2000
Click here to read the entire abstract
Pubmed Data
: Comp Biochem Physiol B Biochem Mol Biol. 2000 Oct;127(2):213-22. PMID:
9663426
Article Published Date
: Oct 01, 2000
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
,
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumin inhibits the invasion of lung cancer cells by modulating the PKCα/Nox-2/ROS/ATF-2/MMP-9 signaling pathway.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Aug ;34(2):691-8. Epub 2015 Jun 9. PMID:
26059056
Article Published Date
: Jul 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Curcumin inhibits the migration and invasion of human and lung cancer cells.
Nov 28, 2009
Click here to read the entire abstract
Pubmed Data
: Cancer Lett. 2009 Nov 28;285(2):127-33. Epub 2009 May 23. PMID:
19477063
Article Published Date
: Nov 28, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Curcumin might provide a novel therapeutic strategy for treating gliomas.
Nov 18, 2005
Click here to read the entire abstract
Pubmed Data
: Biochem Biophys Res Commun. 2005 Nov 18;337(2):510-6. Epub 2005 Sep 21. PMID:
16198311
Article Published Date
: Nov 18, 2005
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Glioma
Pharmacological Actions
:
Antineoplastic Agents
,
Enzyme Inhibitors
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumoids inhibit matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells.
Jul 01, 2010
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2010 Jul;33(7):989-98. Epub 2010 Jul 27. PMID:
20661707
Article Published Date
: Jul 01, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Breast Cancer
,
Cancer Metastasis
Pharmacological Actions
:
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Curcumol suppresses breast cancer cell metastasis.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Integr Cancer Ther. 2016 06 ;15(2):216-25. Epub 2016 Apr 28. PMID:
27125675
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumol
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Deep-sea water has some promise in improving cancer survival by preventing tumor metastasis.
Oct 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Oncol. 2013 Nov ;43(5):1691-700. Epub 2013 Sep 4. PMID:
24008507
Article Published Date
: Oct 31, 2013
Study Type
: In Vitro Study
Additional Links
Substances
:
Water: Deep Sea
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Wnt/β-catenin signaling pathway modulation
[+]
Deguelin inhibits the migration and invasion of lung cancer A549 and H460 cells via regulating actin cytoskeleton rearrangement.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Int J Clin Exp Pathol. 2015 ;8(12):15582-90. Epub 2015 Dec 1. PMID:
26884827
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Deguelin
Diseases
:
Cancer Metastasis
,
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Deguelin inhibits the migration and invasion of U-2 OS human osteosarcoma cells.
Oct 14, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2014 Oct 15 ;19(10):16588-608. Epub 2014 Oct 15. PMID:
25322282
Article Published Date
: Oct 14, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Deguelin
Diseases
:
Cancer Metastasis
,
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Delphinidin, a compound found within eggplant, inhbits the invasiveness of fibrosarcoma cells.
Dec 21, 2009
Click here to read the entire abstract
Pubmed Data
: Biochem Pharmacol. 2009 Dec 21. Epub 2009 Dec 21. PMID:
9581517
Article Published Date
: Dec 21, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Eggplant
Diseases
:
Cancer Metastasis
Pharmacological Actions
:
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Diallyl trisulfide (DATS) suppresses the metastasis of the MDA-MB-231 and HS 578T breast cancer cell lines in a dose dependant manner.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2015 ;10(4):e0123781. Epub 2015 Apr 30. PMID:
25927362
Article Published Date
: Dec 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Garlic
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Dose Response
[+]
Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells.
Jan 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2014 Feb ;5(2):381-9. PMID:
24413695
Article Published Date
: Jan 31, 2014
Study Type
: In Vitro Study
Additional Links
Substances
:
Anthocyanins
,
Gallic Acid
Diseases
:
Fibrosarcoma
Pharmacological Actions
:
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
DIM exhibits an anti-IL6-like activity by inhibiting p-STAT3 enhanced ovarian cancer cell proliferation and in vitro metastasis-associated events.
Oct 27, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Oncol (Dordr). 2015 Oct 28. Epub 2015 Oct 28. PMID:
26510945
Article Published Date
: Oct 27, 2015
Study Type
: In Vitro Study
Additional Links
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Interleukin-6 Downregulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Diosgenin inhibits migration and invasion of human prostate cancer PC-3 cells.
Dec 31, 2010
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: PLoS One. 2011 ;6(5):e20164. Epub 2011 May 23. PMID:
21629786
Article Published Date
: Dec 31, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Diosgenin
Diseases
:
Prostate Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Dose Response
[+]
Effect of pomegranate fruit supplementation on performance and various markers in athletes and active subjects.
Sep 11, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Vitam Nutr Res. 2019 Sep 12:1-15. Epub 2019 Sep 12. PMID:
31512981
Article Published Date
: Sep 11, 2019
Study Type
: Review
Additional Links
Substances
:
Pomegranate
Diseases
:
Athletic Performance
Pharmacological Actions
:
Antioxidants
,
Malondialdehyde Down-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2018 Apr 1:1-12. Epub 2018 Apr 1. PMID:
29607740
Article Published Date
: Mar 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Chrysin
,
Curcumin
Diseases
:
Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Embelin can abrogate breast cancer cell invasion and metastasis.
May 31, 2016
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2016 Jun ;30(6):1021-32. Epub 2016 Mar 31. PMID:
27030214
Article Published Date
: May 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
False Black Pepper
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Enterolactone, a mammalian lignan derived from flax lignan, down-regulates processes in breast cancer cells associated with metastasis.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Indian J Cancer. 2012 Jan-Mar;49(1):181-7. PMID:
22842186
Article Published Date
: Dec 31, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Enterolactone
Diseases
:
Breast Cancer: Male
Pharmacological Actions
:
Matrix metalloproteinase-14 (MMP-14) inhibitor
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ferulic acid influences cell cycle arrest, apoptosis, invasion, migration, and colony formation in TT cells.
Sep 02, 2015
Click here to read the entire abstract
Pubmed Data
: Tumour Biol. 2015 Sep 3. Epub 2015 Sep 3. PMID:
26334619
Article Published Date
: Sep 02, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Ferulic acid
Diseases
:
Thyroid Cancer
Pharmacological Actions
:
Anti-metastatic
,
Anticarcinogenic Agents
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Fisetin can be used in the future, as a target for the treatment of metastasis of human osteosarcoma cells.
Apr 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: In Vivo. 2019 May-Jun;33(3):801-810. PMID:
31028200
Article Published Date
: Apr 30, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix Metalloproteinase-7 (MMP-7) Inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fisetin inhibits cell migration via inducing HO-1 and reducing MMPs expression in breast cancer cell lines.
Jul 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Aug 1 ;120:528-535. Epub 2018 Aug 1. PMID:
30076913
Article Published Date
: Jul 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Heme oxygenase-1 up-regulation
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Nrf2 activation
[+]
Fisetin inhibits the growth and migration in the A549 human lung cancer cell line.
Feb 28, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2018 Mar ;15(3):2667-2673. Epub 2017 Dec 21. PMID:
29467859
Article Published Date
: Feb 28, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Fisetin
Diseases
:
Lung Cancer
Pharmacological Actions
:
Apoptotic
,
Cyclin D1 Down-Regulation
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Formononetin inhibits proliferation and metastasis of ovarian cancer cells.
Jul 14, 2018
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2018 Jul 15 ;221:91-99. Epub 2018 Apr 13. PMID:
29660466
Article Published Date
: Jul 14, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Formononetin
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fucoidan may be a promising therapeutic agent for human breast cancers.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biol Pharm Bull. 2019 ;42(3):442-447. PMID:
30828076
Article Published Date
: Dec 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Breast Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Fucoidan-Vitamin C complex suppresses tumor invasion.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2009 Nov ;35(5):1183-9. PMID:
19787274
Article Published Date
: Oct 31, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Fucoidan
,
Vitamin C
Diseases
:
Cancer Metastasis
,
Cancers: All
,
Fibrosarcoma
,
Oxidative Stress
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Antioxidants
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Gallic acid appears to break down neoplastic phenotype of oral squamous cell carcinoma cells by interfering with leptin pathway.
Dec 09, 2017
Click here to read the entire abstract
Pubmed Data
: Pathol Res Pract. 2017 Dec 10. Epub 2017 Dec 10. PMID:
29254802
Article Published Date
: Dec 09, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Gallic Acid
Diseases
:
Oral Cancer
Pharmacological Actions
:
Chemotherapeutic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Garcinone E exerts anticancer activities by inducing apoptosis and suppressing migration and invasion in ovarian cancer cells.
Sep 05, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Sep 6 ;7(1):10718. Epub 2017 Sep 6. PMID:
28878295
Article Published Date
: Sep 05, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Garcinia Mangostana
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Apoptotic
,
Garcinia Mangostana
,
ovarian cancer
[+]
Gene expression changes in pomegranate peel extract-treated triple-negative breast cancer cells.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Rep Biochem Mol Biol. 2018 Oct ;7(1):102-109. PMID:
30324124
Article Published Date
: Sep 30, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Geraniin inhibits migration and invasion of human osteosarcoma cancer cells.
Sep 30, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Anticancer Drugs. 2017 Oct ;28(9):959-966. PMID:
28704237
Article Published Date
: Sep 30, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Germanium
Diseases
:
Cancer Metastasis
,
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside compound K attenuates metastatic growth of hepatocellular carcinoma.
Feb 28, 2011
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2011 Mar ;77(5):428-33. Epub 2010 Oct 26. PMID:
20979019
Article Published Date
: Feb 28, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antineoplastic Agents
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Ginsenoside Rg3 inhibits migration and invasion of nasopharyngeal carcinoma cells.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Res Int. 2019 ;2019:8407683. Epub 2019 Feb 24. PMID:
30915362
Article Published Date
: Dec 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Nasopharyngeal Cancer
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Ginsenoside Rg3 sensitizes human non-small cell lung cancer cells to γ-radiation by targeting the nuclear factor-κB pathway.
Jun 30, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2015 Jul ;12(1):609-14. Epub 2015 Feb 27. PMID:
25738799
Article Published Date
: Jun 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Carcinoma: Non-Small-Cell Lung
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Radiosensitizer
,
Vascular Endothelial Growth Factor Inhibitors
[+]
H. erinaceus may be considered as a potent antiangiogenesis candidate to treat diseases with impaired inflammation and cancer.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2016 ;2016:8257238. Epub 2015 Dec 28. PMID:
26823953
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Lion's Mane (Hericium Erinaceus)
Diseases
:
Cancers: All
,
Inflammation
Pharmacological Actions
:
Anti-Angiogenic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Harmine suppresses the proliferation and migration of human ovarian cancer cells.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2017 Nov ;38(5):2927-2934. Epub 2017 Sep 13. PMID:
28901502
Article Published Date
: Oct 31, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Psychedelics:All
Diseases
:
Ovarian Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Harmine was also able to inhibit tumor cell proliferation, invasion, and migration in vitro.
Dec 31, 2010
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2011 ;30(2):123-37. PMID:
21967457
Article Published Date
: Dec 31, 2010
Study Type
: In Vitro Study
Additional Links
Substances
:
Syrian rue
Diseases
:
Cancer Metastasis
,
Lung Cancer
,
Malignant Melanoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
[+]
Hesperidin inhibited the migratory and invasive capabilities of A549 human non-small cell lung cancer cells.
Mar 27, 2018
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2018 Mar 28. Epub 2018 Mar 28. PMID:
29604270
Article Published Date
: Mar 27, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Non-Small-Cell Lung Carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Anti-metastatic
,
Hesperidin
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Non-Small-Cell Lung Carcinoma
[+]
Hesperidin inhibits synovial cell inflammation and macrophage polarization.
Apr 03, 2019
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2019 Apr 4. Epub 2019 Apr 4. PMID:
30954464
Article Published Date
: Apr 03, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Hesperidin
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix Metalloproteinase-13 (MMP-13) Inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
High dose of berberine can induce cell apoptosis by ROS generation while low dose of BBR can inhibit migration and invasion of HCC cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
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Pubmed Data
: Int J Mol Sci. 2016;17(4). Epub 2016 Apr 16. PMID:
27092498
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Berberine
Diseases
:
Liver Cancer
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Anti-metastatic
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
High-dose tanshinone IIA suppresses astrocytoma cell proliferation, migration while promoting apoptosis
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Neurochem Res. 2018 Sep ;43(9):1855-1861. Epub 2018 Jul 31. PMID:
30066161
Article Published Date
: Aug 31, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Tanshinone IIA
Diseases
:
Astrocytoma
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Honeybush tea may have potential anti-osteoclastogenic effects.
Oct 27, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Environ Res Public Health. 2015 Oct 28 ;12(11):13779-93. Epub 2015 Oct 28. PMID:
26516894
Article Published Date
: Oct 27, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Honeybush
Diseases
:
Osteoporosis
Pharmacological Actions
:
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Osteoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Huaier is a potent anti-tumor and immunomodulatory drug, which could inhibit the infiltration of M2-macrophages in breast cancer microenvironment.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2016 ;6:20049. Epub 2016 Feb 1. PMID:
26831282
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Huaier (Trametes robiniophila murr)
Diseases
:
Breast Cancer
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Antiproliferative
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Dose Response
[+]
Inhibition of oral cancer metastasis by melatonin can provide crucial preventive and therapeutic protection against oral cancer.
Mar 08, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26980735
Article Published Date
: Mar 08, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Melatonin
Diseases
:
Oral Cancer
Pharmacological Actions
:
Anti-metastatic
,
Chemotherapeutic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Inhibitory effect of damulin B from gynostemma pentaphyllum on human lung cancer cells.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2019 Mar ;85(5):394-405. Epub 2018 Dec 18. PMID:
30562828
Article Published Date
: Feb 28, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Gynostemma
Diseases
:
Lung Cancer
Pharmacological Actions
:
Anti-metastatic
,
Antiproliferative
,
Apoptotic
,
Cell cycle arrest
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Intake of arctigenin could be an effective supplement for breast cancer patients.
Dec 28, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Oncol. 2016 Dec 29. Epub 2016 Dec 29. PMID:
28035371
Article Published Date
: Dec 28, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Arctigenin
,
Burdock
Diseases
:
Breast Cancer
,
Breast Cancer: Triple Negative
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Isoliquiritigenin can inhibit migration and invasion of human glioma stem cells.
May 24, 2018
Click here to read the entire abstract
Pubmed Data
: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 May 25 ;47(2):181-186. PMID:
30226314
Article Published Date
: May 24, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Isoliquiritigenin
Diseases
:
Glioma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Cancer Stem Cells
[+]
Isothiocyanates could be potential agents for the prevention of C6 glioma cell migration and invasion.
Sep 17, 2015
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2015 Sep 18. Epub 2015 Sep 18. PMID:
26397194
Article Published Date
: Sep 17, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Isothiocyanates
,
Sulforaphane
Diseases
:
Glioma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Isothiocyanates suppress the invasion and metastasis of tumors.
Sep 07, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oncotarget. 2017 Sep 8 ;8(38):63949-63962. Epub 2017 Jul 12. PMID:
28969043
Article Published Date
: Sep 07, 2017
Study Type
: In Vitro Study
Additional Links
Substances
:
Benzyl isothiocyanate
,
Phenethyl isothiocyanate
Diseases
:
Cancers: All
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Justicia gendarussa may have potential use in the management of inflammatory conditions such as arthritis.
May 31, 2011
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2011 Jun ;49(6):648-52. PMID:
21554007
Article Published Date
: May 31, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Justicia gendarussa
Diseases
:
Arthritis
,
Inflammation
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Nitric Oxide Inhibitor
Additional Keywords
:
Anti-Inflammatory Agents
,
arthritis
,
Inflammation
,
Justicia gendarussa
,
Lipopolysaccharide-Induced Toxicity
,
Plant Extracts
[+]
Korean red ginseng extract can enhance the anticancer activity of imatinib mesylate and may have a substantial potential in the treatment of chronic myelogenous leukemia.
Apr 07, 2015
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2015 Apr 8. Epub 2015 Apr 8. PMID:
25857479
Article Published Date
: Apr 07, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Ginseng (Korean)
Diseases
:
Leukemia: Chronic myelogenous leukemia (CML)
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Bcl-2 protein down-regulation
,
Chemosensitizer
,
Cyclooxygenase 2 Inhibitors
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor Inhibitors
Additional Keywords
:
Natural Substance/Drug Synergy
,
Plant Extracts
[+]
Licoricidin in Glycyrrhiza uralensis inhibits lung metastasis of 4T1 mammary carcinoma cells.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2016 ;17(6). Epub 2016 Jun 14. PMID:
27314329
Article Published Date
: Dec 31, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Licorice
Diseases
:
Breast Cancer
,
Breast Cancer: Lung Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Plant Extracts
[+]
Liposomal curcumin targeting endometrial cancer through the NF-κB pathway.
Jul 17, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cell Physiol Biochem. 2018 Jul 18 ;48(2):569-582. Epub 2018 Jul 18. PMID:
30021217
Article Published Date
: Jul 17, 2018
Study Type
: In Vitro Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endometrial Cancer
Pharmacological Actions
:
Antiproliferative
,
Apoptotic
,
Chemopreventive
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
NF-kappaB Inhibitor
[+]
Long-term exposure to oroxylin A inhibits metastasis by suppressing CCL2 in oral squamous cell carcinoma cells.
Mar 11, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Cancers (Basel). 2019 Mar 12 ;11(3). Epub 2019 Mar 12. PMID:
30871117
Article Published Date
: Mar 11, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Flavonoids
Diseases
:
Oral Cancer
,
Squamous cell carcinoma
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Loquat extract suppress the adhesion, migration and invasion of human breast cancer cell line.
Jan 01, 2009
Click here to read the entire abstract
Pubmed Data
: Nutr Res Pract. 2009;3(4):259-64. Epub 2009 Dec 31. PMID:
20098577
Article Published Date
: Jan 01, 2009
Study Type
: In Vitro Study
Additional Links
Substances
:
Loquat Leaves
Diseases
:
Breast Cancer
,
Breast Cancer: Metastatic
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Loquat leaves have anti-metastatic properties in mouse melanoma cells.
Mar 01, 2011
Click here to read the entire abstract
Pubmed Data
: Arch Pharm Res. 2011 Mar;34(3):425-36. Epub 2011 May 6. PMID:
21547674
Article Published Date
: Mar 01, 2011
Study Type
: In Vitro Study
Additional Links
Substances
:
Loquat Leaves
Diseases
:
Cancer Metastasis
,
Melanoma
,
Melanoma: Metastasis
Pharmacological Actions
:
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Onco Targets Ther. 2017 ;10:4023-4028. Epub 2017 Aug 11. PMID:
28860810
Article Published Date
: Dec 31, 2016
Study Type
: In Vitro Study
Additional Links
Substances
:
Quercetin
Diseases
:
Glioblastoma
Pharmacological Actions
:
Angiogenesis Inhibitors
,
Anti-metastatic
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
,
Vascular Endothelial Growth Factor A Inhibitor
[+]
Low-molecular-weight fucoidan may have therapeutic potential in the treatment of rheumatoid arthritis.
Sep 30, 2015
Click here to read the entire abstract
Pubmed Data
: Inflammation. 2015 Oct ;38(5):1777-86. PMID:
25787883
Article Published Date
: Sep 30, 2015
Study Type
: In Vitro Study
Additional Links
Substances
:
Fucoidan
Diseases
:
Rheumatoid Arthritis
Pharmacological Actions
:
Apoptotic
,
Interleukin-1 beta downregulation
,
Matrix metalloproteinase-1 (MMP-1) inhibitor
,
Matrix metalloproteinase-3 (MMP-3) inhibitor
,
Matrix metalloproteinase-9 (MMP-9) inhibitor
[+]
Lupeol can be used in anti-metastasis of human osteosarcoma cells.
Aug 31, 2019
Click here to read the entire abstract
Pubmed Data
: Biosci Biotechnol Biochem. 2019 Sep ;83(9):1729-1739. Epub 2019 Apr 22. PMID:
31010399
Article Published Date
: Aug 31, 2019
Study Type
: In Vitro Study
Additional Links
Substances
:
Lupeol
Diseases
:
Cancer Metastasis
,
Osteosarcoma
Pharmacological Actions
:
Anti-metastatic
,