Interleukin-1 beta downregulation

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340 Substances Researched for Interleukin-1 beta downregulation
NameACCKFocus
Curcumin4291Locked
Ginsenosides2849Locked
Resveratrol2141Locked
Flavonoids1534Locked
Omega-3 Fatty Acids534Locked
Berberine1830Locked
Paeoniflorin1628Locked
Polyphenols1627Locked
Vitamin D423Locked
Ginger1222Locked
Hesperidin1122Locked
Sulforaphane1321Locked
Astaxanthin1020Locked
DHA (Docosahexaenoic Acid)220Locked
Green Tea719Locked
Melatonin1019Locked
Naringenin 1118Locked
Puerarin1018Locked
Rose 1118Locked
Thymoquinone1018Locked
Astragaloside1017Locked
Anthocyanins416Locked
Quercetin916Locked
Vitamin C716Locked
Rosmarinic acid615Locked
Tanshinone IIA915Locked
Magnolol714Locked
Asiatic Acid913Locked
Fisetin713Locked
Fucoidan813Locked
Strawberry313Locked
Black Tea312Locked
Cyanidin 3-glucoside212Locked
EGCG (Epigallocatechin gallate)612Locked
Gastrodin712Locked
Honey212Locked
Phloretin512Locked
Probiotics212Locked
Pterostilbene612Locked
Tart Cherry212Locked
Vitamin E212Locked
Dandelion 811Locked
Ginseng (Korean)611Locked
Purslane611Locked
Almond110Locked
Bacillus coagulans110Locked
Betulinic acid410Locked
Bilberry110Locked
Bloodroot110Locked
Breast Milk 110Locked
Delphinidin110Locked
Echinacea110Locked
Eicosapentaenoic acid (EPA) 110Locked
Ellagic Acid510Locked
Lutein110Locked
Moringa oleifera610Locked
Safflower110Locked
Virgin Coconut Oil110Locked
Vitamin A110Locked
Chrysanthemum Indicum59Locked
Citrus naringin69Locked
Diosgenin59Locked
Geraniol 59Locked
Honokiol69Locked
Huperzine59Locked
Luteolin69Locked
Nobiletin 69Locked
Punicalagin39Locked
Red Sage59Locked
Tangeretin 69Locked
Vitexins39Locked
Wogonin69Locked
Cannabidiol58Locked
Genipin58Locked
Lychee48Locked
Rutin48Locked
Shikonin48Locked
Stilbenes48Locked
Allicin47Locked
Apigenin67Locked
Bee Venom47Locked
Chrysin47Locked
Kaempferol47Locked
Kefir47Locked
Myricetin47Locked
Oleuropein47Locked
Olive leaf extract47Locked
Pomegranate47Locked
Turmeric57Locked
Agaricus Blazei36Locked
Amygdalin36Locked
Ashwagandha46Locked
Chaga Mushroom (Inonotus obliquus)36Locked
Chinese Skullcap 36Locked
Coenzyme Q1036Locked
Gingerol 46Locked
Ginkgo biloba36Locked
Gotu Kola46Locked
Guduchi 46Locked
Hydrogen Water36Locked
Mangiferin46Locked
Palmitoylethanolamide 36Locked
Piperine46Locked
Rosemaric Acid36Locked
Sesamol46Locked
Arctigenin35Locked
Chamomile35Locked
Cinnamaldehyde35Locked
Emodin35Locked
Isoliquiritigenin35Locked
Japanese cypress35Locked
Jujube35Locked
Lotus 45Locked
Lycopene35Locked
MSM (Methylsulfonylmethane)35Locked
Panax Notoginseng35Locked
Parthenolide35Locked
Thymol35Locked
Xanthohumol35Locked
6-Shogaol24Locked
Aloe Vera24Locked
Apocynin24Locked
Baicalein24Locked
Beta-Caryophyllene24Locked
Black Raspberry34Locked
Blueberry34Locked
Caffeic Acid24Locked
Chlorogenic Acid24Locked
Cranberry24Locked
Crocetin24Locked
Crocin24Locked
Eucalyptus24Locked
Ferulic acid24Locked
Frankincense24Locked
Fucoxanthin 24Locked
Lactobacillus reuteri24Locked
Lavender: Essential Oil24Locked
Ligustrazine24Locked
Lion's Mane (Hericium Erinaceus)24Locked
Mulberry24Locked
Myrrh24Locked
Oak24Locked
Piceatannol 24Locked
Procyanidin B2 24Locked
Raspberry24Locked
Royal Jelly34Locked
Soy34Locked
Spikenard34Locked
Sweet Potato: Purple24Locked
Whey24Locked
Antrodia camphorata23Locked
Bergamot23Locked
Carnosic Acid23Locked
Diallyl sulfide23Locked
Diosmin 23Locked
Fish Oil23Locked
Flaxseed23Locked
Garlic23Locked
Grape Seed Extract23Locked
Hemp Seed23Locked
Lactobacillus plantarum23Locked
Manuka Honey23Locked
Oats23Locked
Persimmon 23Locked
Plantago asiatica23Locked
Reishi Mushroom23Locked
Sea buckthorn23Locked
Theaflavins23Locked
Vanillin33Locked
Zerumbone23Locked
18β-Glycyrrhetinic Acid12Locked
Acai12Locked
Alpha-Lipoic Acid12Locked
Amla Fruit12Locked
Amygdalin (laetrile)22Locked
Anemarrhena asphodeloides12Locked
Apples12Locked
Arginine12Locked
Artesunate12Locked
Artichoke12Locked
Arugula12Locked
Aspen12Locked
Astragalus12Locked
Avocado22Locked
Bai Zhu12Locked
Bamboo12Locked
Banana12Locked
Barley12Locked
Billygoat Weed12Locked
Black Currant12Locked
Blue Honeysuckle12Locked
Boron12Locked
Brown Rice12Locked
Cabbage12Locked
Camel Milk 12Locked
Cannabigerol 12Locked
Cannabinoids 12Locked
Cannabis12Locked
Carnosine12Locked
Chaenomeles speciosa12Locked
Chlorella (Algae)12Locked
Chrysanthemum Morifolium12Locked
Citrus Peel 12Locked
Coconut Oil12Locked
Combretum fragrans12Locked
Cucurbitacin E 22Locked
Cystine12Locked
Daidzein12Locked
EPA (Eicosapentaenoic Acid)12Locked
Elm tree12Locked
FOS (Fructooligosaccharides)12Locked
Flavan-3-ols12Locked
Folic Acid 12Locked
Gallic Acid12Locked
Garcinia Mangostana12Locked
Gardenia12Locked
Ginseng12Locked
Ginseng (American)12Locked
Ginseng (Siberian)12Locked
Gold (nanoparticles)12Locked
Gynostemma22Locked
Helenalin12Locked
Hibiscus sabdariffa 12Locked
Hops12Locked
Horsetail12Locked
Hu Zhang (Polygonum cuspidatum)12Locked
Indole-3-Carbinol12Locked
Isoflavones12Locked
Kaempferia parviflora12Locked
Krill12Locked
Lactobacillus Brevis12Locked
Lactobacillus paracasei12Locked
Lactobacillus probiotics12Locked
Lactobacillus rhamnosus 12Locked
Lactobacillus rhamnosus GG12Locked
Lactobacillus salivarius 12Locked
Loquat12Locked
Lupeol12Locked
Magnesium12Locked
Mango 12Locked
Marigold12Locked
Mucuna pruriens (aka Velvet Beans)12Locked
NAC (N-acetyl-L-cysteine)12Locked
Neem12Locked
Nettle12Locked
Nigella sativa (aka Black Seed)12Locked
Oleanolic acid12Locked
Orange12Locked
Oyster Mushroom: Indian12Locked
Passion Flower12Locked
Patchouli12Locked
Perilla 12Locked
Perillaldehyde12Locked
Phyllanthus emblica12Locked
Pipsisssewa12Locked
Propolis: Bee12Locked
Prunella vulgaris12Locked
Psychedelics:All 12Locked
Pulsatilla pratensis12Locked
Pycnogenol (Pine Bark)12Locked
Radish12Locked
Rosemary12Locked
Rubia Cordifolia12Locked
Salvia miltiorrhiza12Locked
Selenium12Locked
Shiitake Mushroom 12Locked
Silymarin12Locked
Sour Cherry22Locked
St. Johns Wort12Locked
Stevia12Locked
Suma (Pfaffia Paniculata)12Locked
Tannic Acid12Locked
Tetrahydrocurcumin12Locked
Theanine12Locked
Thyme22Locked
Toona sinensis 12Locked
Unsaponifiables 22Locked
Urolithin A 12Locked
Ursolic Acid12Locked
Vitamin E: alpha tocopherol12Locked
Wheat Bran12Locked
White Tea12Locked
Yarrow12Locked
Yellow Tea12Locked
Yerba Mate12Locked
Zeaxanthin12Locked
Achillea fragrantissima11Locked
Agrimony11Locked
Apple Polyphenols11Locked
Ayahuasca11Locked
Basil: Sweet11Locked
Benzyl isothiocyanate 11Locked
Beta-Elemene11Locked
Burdock11Locked
Caffeic acid phenethyl ester11Locked
Catechin 11Locked
Cherry: All Varieties11Locked
Coriandrum sativum11Locked
Corn Silk11Locked
Cryptomeria japonica11Locked
Cucurbitacin B 11Locked
Damnacanthal11Locked
Delta-tetrahydrocannabinol (THC)11Locked
Dill11Locked
Evening Primrose Oil11Locked
Fruit: All11Locked
Goji11Locked
Guava11Locked
Isothiocyanates11Locked
Juniper11Locked
Maple11Locked
Meadowsweet11Locked
Medicinal Mushrooms11Locked
Mushrooms: All 11Locked
Palash11Locked
Panax Ginseng11Locked
Phellinus Linteus11Locked
Phyllanthus amarus 11Locked
Pine Needle11Locked
Plantago11Locked
Pomegranate flower11Locked
Prebiotics11Locked
Purple Carrots11Locked
Rhubarb11Locked
Rice Bran11Locked
Saffron11Locked
Salicylic acid11Locked
Seaweed: Brown 11Locked
Sesame Seed Oil 11Locked
Sessile Joyweed11Locked
Silibinin11Locked
Syrian rue11Locked
Vegetables: All 11Locked
Verbascoside11Locked
Vitamin E: Gamma-tocotrienol11Locked
Vitex negundo11Locked
Willow Bark11Locked
Wormwood11Locked
Yoghurt11Locked
Zataria multiflora11Locked

View the Evidence:
1071 Abstracts with Interleukin-1 beta downregulation Research

[+]

A single 20 min session of yogic breathing practice could reduce the levels of key pro-inflammatory biomarkers in saliva.Aug 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2016 Aug 18 ;16:294. Epub 2016 Aug 18. PMID: 27538513
Article Published Date : Aug 17, 2016
Study Type : Human Study
Additional Links
Diseases : Inflammation
Therapeutic Actions : Yogic Breathing
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-8 downregulation
[+]

An anthocyanin mixture reduced the inflammatory response in hypercholesterolemic subjects.Aug 31, 2013

Pubmed Data : Nutr Metab Cardiovasc Dis. 2013 Sep ;23(9):843-9. Epub 2012 Aug 17. PMID: 22906565
Article Published Date : Aug 31, 2013
Study Type : Human Study
Additional Links
Substances : Anthocyanins, Cyanidin 3-glucoside, Delphinidin
Diseases : Atherosclerosis, C-Reactive Protein, High Cholesterol, Hypercholesterolemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Vascular Cell Adhesion Molecule-1 Inhibitor
Additional Keywords : Dose Response, Natural Substance Synergy
[+]

Bloodroot and echinacea offset exercise-associated effects of immune activity.Nov 01, 2009

Pubmed Data : Blood Cells Mol Dis. 2009 Nov-Dec;43(3):298-303. Epub 2009 Sep 19. PMID: 19766513
Article Published Date : Nov 01, 2009
Study Type : Human Study
Additional Links
Substances : Bloodroot, Echinacea
Diseases : Immune Disorders: Low Immune Function, Low Immune Function: Exercise-Induced
Pharmacological Actions : Immunomodulatory, Immunostimulatory, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Breastfeeding protects against illness-induced anorexia and is mediated partially by docosahexaenoic acid.Jan 01, 2008

Pubmed Data : Eur J Clin Nutr. 2008 Jan;62(1):32-8. Epub 2007 Feb 21. PMID: 17311056
Article Published Date : Jan 01, 2008
Study Type : Human Study
Additional Links
Substances : Breast Milk , DHA (Docosahexaenoic Acid)
Diseases : Anorexia: Illness and Vaccine Induced, Vaccine-induced Toxicity
Therapeutic Actions : Breastfeeding
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cashew may have anti-inflammatory activity in rheumatoid arthritis patients.Dec 06, 2006

Pubmed Data : J Ethnopharmacol. 2006 Dec 6;108(3):398-406. Epub 2006 Jun 2. PMID: 16824715
Article Published Date : Dec 06, 2006
Study Type : Human Study
Additional Links
Diseases : Lipopolysaccharide-Induced Toxicity, Rheumatoid Arthritis
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Curcumin could reverse the development of depression and enhance the outcome of antidepressants treatment in major depressive disorder.Jul 31, 2015

Pubmed Data : J Clin Psychopharmacol. 2015 Aug ;35(4):406-10. PMID: 26066335
Article Published Date : Jul 31, 2015
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy, Significant Treatment Outcome
Problem Substances : Antidepressants
[+]

Curcumin suppresses inflammation in the mucosa of children and adults with inflammatory bowel disease. Nov 02, 2009

Pubmed Data : Br J Nutr. 2009 Nov 2:1-9. Epub 2009 Nov 2. PMID: 19878610
Article Published Date : Nov 02, 2009
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Interleukin-1 beta downregulation, Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]

Daily consumption of BC30 by adult’s aged 65-80 y can increase beneficial groups of bacteria in the human gut.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Nutr. 2015 Jul ;145(7):1446-52. Epub 2015 May 6. PMID: 25948780
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Bacillus coagulans
Diseases : C-Reactive Protein, Dysbiosis, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Gastrointestinal Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Microbiota
[+]

Dietary strawberries may have significant analgesic and anti-inflammatory effects in obese adults with established knee osteoarthritis.Aug 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2017 Aug 28 ;9(9). Epub 2017 Aug 28. PMID: 28846633
Article Published Date : Aug 27, 2017
Study Type : Human Study
Additional Links
Substances : Strawberry
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix metalloproteinase-3 (MMP-3) inhibitor
Additional Keywords : Analgesics, Anti-Inflammatory Agents, Osteoarthritis: Knee, Strawberry
[+]

Electroacupuncture has a therapeutic effect on patients wtih osteoarthritis. Jul 01, 2009

Pubmed Data : Zhongguo Zhen Jiu. 2009 Jul;29(7):529-31. PMID: 19835118
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Diseases : Osteoarthritis
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Etiological periodontal treatment with and without low-level laser therapy on IL-1β level.Mar 25, 2018

Pubmed Data : J Biol Regul Homeost Agents. 2018 Mar 26 ;32(2). Epub 2018 Mar 26. PMID: 29577710
Article Published Date : Mar 25, 2018
Study Type : Human Study
Additional Links
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Green tea chewing gum may be a safe adjunct for treatment of gingival inflammation. May 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Shiraz). 2016 Jun ;17(2):149-54. PMID: 27284561
Article Published Date : May 31, 2016
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Gingivitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Honey reduce the probable aggravating effects of intensive cycling training on spermatogenesis and fertility capacity in road cyclists.Apr 30, 2012

Pubmed Data : J Androl. 2012 May-Jun;33(3):449-61. Epub 2011 Jun 2. PMID: 21636735
Article Published Date : Apr 30, 2012
Study Type : Human Study
Additional Links
Substances : Honey
Diseases : Exercise-Induced Hormone Fluctuations, Infertility: Male, Oxidative Stress
Therapeutic Actions : Exercise: Cycling
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Including almonds in diets as a snack may help healthy overweight and obese individuals improve nutritional status and reduce their risk for CVD.Jul 09, 2017

Pubmed Data : Eur J Nutr. 2017 Jul 10. Epub 2017 Jul 10. PMID: 28695324
Article Published Date : Jul 09, 2017
Study Type : Human Study
Additional Links
Substances : Almond, Vitamin E
Diseases : Cardiovascular Disease: Prevention, Obesity, Overweight
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Risk Reduction
[+]

Intake of bilberries has an ameliorating effect on some markers of gingival inflammation reducing gingivitis to a similar extent compared to standard of care.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 ;16(5):10665-73. Epub 2015 May 11. PMID: 25970751
Article Published Date : Dec 31, 2014
Study Type : Human Study
Additional Links
Substances : Bilberry
Diseases : Gingivitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Vascular Endothelial Growth Factor Inhibitors
[+]

Irritable eye syndrome: neuroimmune mechanisms and benefits of selected nutrients.Mar 31, 2014

Pubmed Data : Ocul Surf. 2014 Apr ;12(2):134-45. Epub 2013 Dec 30. PMID: 24725325
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids, Vitamin A, Vitamin D
Diseases : Eye Diseases
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Lutein exerts anti-inflammatory effects in patients with coronary artery disease.May 05, 2017

Pubmed Data : Atherosclerosis. 2017 May 6 ;262:87-93. Epub 2017 May 6. PMID: 28527371
Article Published Date : May 05, 2017
Study Type : Human Study
Additional Links
Substances : Lutein
Diseases : Coronary Artery Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Dose Response
[+]

Montmorency cherries significantly lowered systemic inflammatory and oxidative stress induced by a series of metabolically challenging cycling bouts.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2014 ;6(2):829-43. Epub 2014 Feb 21. PMID: 24566440
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Tart Cherry
Diseases : C-Reactive Protein, Inflammation, Muscle Damage: Exercise-Induced, Oxidative Stress
Pharmacological Actions : Anti Inflammatory, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Omega-3 fatty acids cause a reduction in the mRNA levels for various proteins known to be important in the pathology of osteoarthritis. Jul 01, 2009

Pubmed Data : Osteoarthritis Cartilage. 2009 Jul;17(7):896-905. Epub 2009 Jan 13. PMID: 19217322
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : DHA (Docosahexaenoic Acid), Eicosapentaenoic acid (EPA) , Omega-3 Fatty Acids
Diseases : Osteoarthritis
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 alpha downregulation, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Omega-3 long chain-polyunsaturated fatty acids could have a potential therapeutic impact on chronic inflammation in Duchenne muscular dystrophy.Sep 22, 2017

Pubmed Data : Clin Nutr. 2017 Sep 23. Epub 2017 Sep 23. PMID: 28987470
Article Published Date : Sep 22, 2017
Study Type : Human Study
Additional Links
Substances : Omega-3 Fatty Acids
Diseases : Duchenne's Muscular Dystrophy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Ozone therapy is a potential therapeutic alternative for Multiple sclerosis patients.Sep 14, 2017

Pubmed Data : Eur J Pharmacol. 2017 Sep 15 ;811:148-154. Epub 2017 Jun 13. PMID: 28623000
Article Published Date : Sep 14, 2017
Study Type : Human Study
Additional Links
Diseases : Multiple Sclerosis
Therapeutic Actions : Ozone Therapy
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Phototherapy appears to be a plausible complementary option to reduce the inflammatory component in rheumatoid arthritis.Oct 31, 2015

Pubmed Data : Acta Med Acad. 2015 Nov ;44(2):102-8. PMID: 26702905
Article Published Date : Oct 31, 2015
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Rheumatoid Arthritis
Therapeutic Actions : Light Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Probiotic therapies modestly improved insulin resistance in patients with type 2 diabetes.Aug 31, 2018

Pubmed Data : Diabetes Metab Syndr. 2018 Sep ;12(5):617-624. Epub 2018 Apr 10. PMID: 29661605
Article Published Date : Aug 31, 2018
Study Type : Human Study
Additional Links
Substances : Probiotics
Diseases : Diabetes Mellitus: Type 2, Insulin Resistance
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sesamin can relieve clinical symptoms and pathological changes that caused by inflammatory impairment in patients with rheumatoid arthritis.Aug 31, 2019

Pubmed Data : Phytother Res. 2019 Sep ;33(9):2421-2428. Epub 2019 Jul 15. PMID: 31309643
Article Published Date : Aug 31, 2019
Study Type : Human Study
Additional Links
Substances : Sesamin
Diseases : Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Successful therapy of Clostridium difficile infection with fecal microbiota transplantation.Nov 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Physiol Pharmacol. 2016 Dec ;67(6):859-866. PMID: 28195066
Article Published Date : Nov 30, 2016
Study Type : Human Study
Additional Links
Diseases : C-Reactive Protein, Clostridium Infections, Diarrhea, Inflammation
Therapeutic Actions : Microbiota Transfer Therapy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The findings of the present trial suggested that curcumin may exert immunomodulatory effects via altering the circulating concentrations of IL-1β, IL-4, and VEGF.Dec 31, 2013

Pubmed Data : ScientificWorldJournal. 2014 ;2014:898361. Epub 2014 Feb 11. PMID: 24678280
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Substances : Curcumin
Diseases : Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-4 downregulation, VEGFR3 inhibition
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

The impact of virgin coconut oil and high-oleic safflower oil on body composition, lipids, and inflammatory markers in postmenopausal women.Mar 08, 2017

Pubmed Data : J Med Food. 2017 Mar 9. Epub 2017 Mar 9. PMID: 28277823
Article Published Date : Mar 08, 2017
Study Type : Human Study
Additional Links
Substances : Safflower, Virgin Coconut Oil
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
Additional Keywords : Plant Oils
[+]

The oral intake of Pycnogenol down-regulated the gene expression of various cartilage degradation markers in the patients' chondrocytes.Dec 15, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Dec 16 ;17(1):537. Epub 2017 Dec 16. PMID: 29246219
Article Published Date : Dec 15, 2017
Study Type : Human Study
Additional Links
Substances : Flavonoids
Diseases : Osteoarthritis: Knee
Pharmacological Actions : Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor
[+]

The present study provides evidence that Diabetea tea has hypoglycemic and antihyperlipidemic properties.Dec 23, 2016

Pubmed Data : J Ethnopharmacol. 2016 Dec 24 ;194:1069-1077. Epub 2016 Oct 27. PMID: 27989874
Article Published Date : Dec 23, 2016
Study Type : Human Study
Additional Links
Substances : Black Tea
Diseases : Diabetes Mellitus: Type 2, Inflammation
Pharmacological Actions : Hypoglycemic Agents, Hypolipidemic, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-8 downregulation
Additional Keywords : BLACK TEA, Diabetes mellitus: Type 2, Hypoglycemic Agents, Hypolipidemic, Inflammation, Plant Extracts
[+]

Weight loss and vitamin D supplementation may act synergistically to reduce levels of meta-inflammation.Sep 23, 2018

Pubmed Data : Clin Endocrinol (Oxf). 2018 Sep 24. Epub 2018 Sep 24. PMID: 30246883
Article Published Date : Sep 23, 2018
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Inflammation, Obesity
Therapeutic Actions : Weight Reduction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Astragaloside potentially serve as a promising and effective therapeutic agent for treating osteoarthritis patients.Jul 31, 2019

Pubmed Data : Immunopharmacol Immunotoxicol. 2019 Aug ;41(4):497-503. Epub 2019 Jul 11. PMID: 31293216
Article Published Date : Jul 31, 2019
Study Type : Animal Study, Human In Vitro
Additional Links
Substances : Astragaloside
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Betulinic acid inhibited IL-1β-induced inflammation in osteoarthritis chondrocytes by activating PPAR-γ.Sep 17, 2015

Pubmed Data : Int Immunopharmacol. 2015 Sep 18. Epub 2015 Sep 18. PMID: 26391061
Article Published Date : Sep 17, 2015
Study Type : Human In Vitro
Additional Links
Substances : Betulinic acid
Diseases : Inflammation, Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Melatonin is a potential candidate compound for the treatment of proinflammatory disorders.Aug 31, 2012

Pubmed Data : J Pineal Res. 2012 Sep ;53(2):154-65. Epub 2012 Feb 21. PMID: 22348531
Article Published Date : Aug 31, 2012
Study Type : Human In Vitro
Additional Links
Substances : Melatonin
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Nitric Oxide Inhibitor, Prostaglandin PGE2 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Dose Response
[+]

Paeoniflorin may provide a new therapeutic approach to regulate P2X7R-mediated pathologic responses of primary Sjögren's syndrome.Aug 31, 2015

Pubmed Data : Int Immunopharmacol. 2015 Sep ;28(1):115-20. Epub 2015 Jun 3. PMID: 26049028
Article Published Date : Aug 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Paeoniflorin
Diseases : Sjogren's Syndrome
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Phloretin inhibits interleukin-1β-induced COX-2 and ICAM-1 in human lung epithelial cells.May 31, 2015

Pubmed Data : Food Funct. 2015 Jun ;6(6):1960-7. PMID: 25996641
Article Published Date : May 31, 2015
Study Type : Human In Vitro
Additional Links
Substances : Phloretin
Diseases : Experimental Lung Inflammation
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Prostaglandin PGE2 downregulation
[+]

Punicalagin and EGCG can rescue keratinocyte viability and attenuate the inflammatory responses of cells due to airborne particles.Mar 21, 2018

Pubmed Data : Skin Pharmacol Physiol. 2018 Mar 22 ;31(3):134-143. Epub 2018 Mar 22. PMID: 29566388
Article Published Date : Mar 21, 2018
Study Type : Human In Vitro
Additional Links
Substances : EGCG (Epigallocatechin gallate), Punicalagin
Diseases : Air Pollution Linked Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Resveratrol may be a useful preventative therapeutic for pregnancies complicated by inflammation and insulin resistance.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2017 ;12(3):e0173373. Epub 2017 Mar 9. PMID: 28278187
Article Published Date : Dec 31, 2016
Study Type : Human In Vitro
Additional Links
Substances : Resveratrol
Diseases : Gestational Diabetes, Inflammation, Pregnancy Complications
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 alpha downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Rosmarinic acid may be a potential candidate for the treatment of psoriasis.Jun 14, 2016

Pubmed Data : Life Sci. 2016 Jun 15 ;155:189-94. Epub 2016 May 17. PMID: 27210890
Article Published Date : Jun 14, 2016
Study Type : Human In Vitro
Additional Links
Substances : Rosmarinic acid
Diseases : Psoriasis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Sulforaphane rescues amyloid-β peptide-mediated decrease in MerTK expression through its anti-inflammatory effect.Mar 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Neuroinflammation. 2018 Mar 12 ;15(1):75. Epub 2018 Mar 12. PMID: 29530050
Article Published Date : Mar 11, 2018
Study Type : Human In Vitro
Additional Links
Substances : Sulforaphane
Diseases : Alzheimer's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

The antioxidants astaxanthin and vitamin C promoted a significant improvement in the function of neutrophils and in the redox status.Jun 28, 2012

Pubmed Data : Toxicol In Vitro. 2012 Jun 29. Epub 2012 Jun 29. PMID: 22750055
Article Published Date : Jun 28, 2012
Study Type : Human In Vitro
Additional Links
Substances : Astaxanthin, Vitamin C
Diseases : Advanced Glycation Endproduct (AGE) Formation, Neutrophils: Damaged
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Vitexin alleviates interleukin-1β induced inflammatory responses in chondrocytes from osteoarthritis patients.May 03, 2019

Pubmed Data : Scand J Immunol. 2019 May 4:e12773. Epub 2019 May 4. PMID: 31055848
Article Published Date : May 03, 2019
Study Type : Human In Vitro
Additional Links
Substances : Vitexins
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-3 (MMP-3) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Ginger efficiently reduced the lung damage and protected the lungs from severe damage due to hyperoxia and inflammation. Aug 15, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Turk J Med Sci. 2018 Aug 16 ;48(4):892-900. Epub 2018 Aug 16. PMID: 30121057
Article Published Date : Aug 15, 2018
Study Type : Human: Case Report
Additional Links
Substances : Ginger
Diseases : Bronchopulmonary Dysplasia, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

1,8-cineol appears to be able to augment protection against influenza viral infection in mice.Jul 31, 2016

Pubmed Data : Inflammation. 2016 Aug ;39(4):1582-93. PMID: 27351430
Article Published Date : Jul 31, 2016
Study Type : Animal Study
Additional Links
Substances : Eucalyptus
Diseases : Inflammation, Influenza, Pneumonia
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

18β-Glycyrrhetinic acid significantly attenuated H. pylori-infected gastritis in gerbils.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2016 ;2016:4943793. Epub 2016 Feb 24. PMID: 27006947
Article Published Date : Dec 31, 2015
Study Type : Animal Study
Additional Links
Substances : 18β-Glycyrrhetinic Acid
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside prevents lipopolysaccharide-induced depressive-like behaviours.Dec 31, 2016

Pubmed Data : Behav Pharmacol. 2017 08 ;28(5):365-374. PMID: 28410266
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Diseases : Anxiety, Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

6-Gingerol abates benzo[a]pyrene-induced colonic injury.Apr 17, 2019

Pubmed Data : Chem Biol Interact. 2019 Apr 18 ;307:1-7. Epub 2019 Apr 18. PMID: 31004597
Article Published Date : Apr 17, 2019
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Benzo[a]pyrene-induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Gastroprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Benzo(a)pyrene
[+]

6-Gingerol exerts protective effects against ischemia reperfusion induced intestinal mucosa injury.Feb 03, 2017

Pubmed Data : Pharmacol Res. 2017 Feb 4 ;119:137-148. Epub 2017 Feb 4. PMID: 28167239
Article Published Date : Feb 03, 2017
Study Type : Animal Study
Additional Links
Substances : Gingerol
Diseases : Ischemia
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

6-Shogaol reduces progression of experimental endometriosis.Oct 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Korean J Physiol Pharmacol. 2018 Nov ;22(6):627-636. Epub 2018 Oct 25. PMID: 30402023
Article Published Date : Oct 31, 2018
Study Type : Animal Study
Additional Links
Substances : 6-Shogaol
Diseases : Endometriosis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Postaglandin PGE2 downregulation
[+]

A combination therapy of betulinic acid and fluvastatin that reduces the risk of both rheumatoid arthritis and CVD.Aug 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Sep ;93:681-694. Epub 2017 Jul 8. PMID: 28692940
Article Published Date : Aug 31, 2017
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Arthritis, Cardiovascular Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A compound in Chinese skullcap known as baicalein reduces the inflammatory process in a rodent model of diabetic retinopathyMay 01, 2009

Pubmed Data : Invest Ophthalmol Vis Sci. 2009 May;50(5):2319-27. Epub 2008 Nov 14. PMID: 19011009
Article Published Date : May 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain: Microglial Activation, Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor A Inhibitor
[+]

A dietary supplement of nuciferine rich in lotus leaf may have potential for the prevention and treatment of hyperuricemia with kidney inflammation.Jan 14, 2015

Pubmed Data : Eur J Pharmacol. 2015 Jan 15 ;747:59-70. Epub 2014 Dec 8. PMID: 25499818
Article Published Date : Jan 14, 2015
Study Type : Animal Study
Additional Links
Substances : Lotus
Diseases : Hyperuricemia, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Renoprotective
[+]

A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer.Mar 26, 2019

Pubmed Data : Eur J Nutr. 2019 Mar 27. Epub 2019 Mar 27. PMID: 30919084
Article Published Date : Mar 26, 2019
Study Type : Animal Study
Additional Links
Substances : Bergamot, Flavonoids
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

A proprietary blend of herbs suppresses bladder oxidative stress and inflammation in a rat model of partial bladder outlet obstruction.Jul 01, 2009

Pubmed Data : J Urol. 2009 Jul;182(1):382-90. Epub 2009 May 17. PMID: 19447421
Article Published Date : Jul 01, 2009
Study Type : Animal Study
Additional Links
Substances : Aspen, Horsetail, Pipsisssewa, Pulsatilla pratensis, Wheat Bran
Diseases : Bladder Dysfunction , Bladder Outlet Obstruction, Oxidative Stress
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

A standardized extract of neem has neuroprotective effects in partial sciatic nerve injury.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : EXCLI J. 2017 ;16:546-565. Epub 2017 Apr 18. PMID: 28694757
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Neem
Diseases : Nerve Injuries
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

A variety of orange by-products could be used as food supplements in the potential amelioration of inflammatory bowel diseases.Sep 18, 2018

Pubmed Data : Food Funct. 2018 Sep 19 ;9(9):4888-4896. PMID: 30167607
Article Published Date : Sep 18, 2018
Study Type : Animal Study
Additional Links
Substances : Orange
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aastragaloside IV can alleviate inflammation and enhance immunity in rats with experimental periodontitis.Apr 24, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Braz Oral Res. 2019 Apr 25 ;33:e032. Epub 2019 Apr 25. PMID: 31038567
Article Published Date : Apr 24, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Immunostimulatory, Interleukin-1 beta downregulation, Interleukin-2 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Açaí demonstrated protective effects against AOM/DSS-induced colon carcinogenesis.Mar 14, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Gut Liver. 2017 Mar 15 ;11(2):243-252. PMID: 27965474
Article Published Date : Mar 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Acai
Diseases : Colon Cancer, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Anticarcinogenic Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Achillea Millefolium hydro alcoholic extract protects pancreatic cells.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Cell Med. 2014 ;3(4):255-62. PMID: 25635252
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Yarrow
Diseases : Diabetes Mellitus: Type 1
Pharmacological Actions : Interleukin-1 beta downregulation, Pancreato Protective Agents
Additional Keywords : Gene Expression Regulation, Plant Extracts
[+]

Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.Dec 31, 2017

Pubmed Data : Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID: 29128856
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Chlorogenic Acid
Diseases : Chemically-Induced Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Administration of biochanin A can improve and postpone retinopathy.Nov 30, 2018

Pubmed Data : Can J Diabetes. 2018 Dec ;42(6):639-644. Epub 2018 Apr 3. PMID: 30054234
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Diabetic Retinopathy
Pharmacological Actions : Anti-Inflammatory Agents, Hypoglycemic Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Administration of Epigallocatechin-3-gallate resulted in a significant reduction in bone loss.Sep 06, 2015

Pubmed Data : Int Immunopharmacol. 2015 Sep 7. Epub 2015 Sep 7. PMID: 26359545
Article Published Date : Sep 06, 2015
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Gingivitis, Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Aegle marmelos bark extract is active in attenuating the neuropathic pain caused by vincristine.Jun 20, 2019

Pubmed Data : Nutr Neurosci. 2019 Jun 21:1-11. Epub 2019 Jun 21. PMID: 31221045
Article Published Date : Jun 20, 2019
Study Type : Animal Study
Additional Links
Substances : Bael
Diseases : Neuropathic Pain
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Agaricus blazei polysaccharide has a protective effect on cadmium induced damage in chicken spleens.Oct 13, 2017

Pubmed Data : Biol Trace Elem Res. 2017 Oct 14. Epub 2017 Oct 14. PMID: 29032405
Article Published Date : Oct 13, 2017
Study Type : Animal Study
Additional Links
Substances : Agaricus Blazei
Diseases : Cadmium Poisoning
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Alkali-soluble sweet potato polysaccharide can be developed as a novel anti-inflammation agent.Mar 19, 2019

Pubmed Data : Int J Biol Macromol. 2019 Mar 20 ;131:484-494. Epub 2019 Mar 20. PMID: 30904524
Article Published Date : Mar 19, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Sweet Potato: Purple
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Allicin attenuates liver oxidative stress and inflammation.Sep 27, 2016

Pubmed Data : J Agric Food Chem. 2016 Sep 28 ;64(38):7104-13. Epub 2016 Sep 19. PMID: 27584700
Article Published Date : Sep 27, 2016
Study Type : Animal Study
Additional Links
Substances : Allicin
Diseases : Alcohol Toxicity , Fatty Liver, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Alcohol Toxicity, Allicin, Anti-Inflammatory Agents, Fatty Liver, Inflammation, oxidative stress
[+]

Aloesin has the therapeutic potential for treating cutaneous wounds.May 14, 2017

Pubmed Data : Phytomedicine. 2017 May 15 ;28:19-26. Epub 2017 Mar 4. PMID: 28478809
Article Published Date : May 14, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Aloe Vera
Diseases : Wound Healing
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Alpha-lipoic acid improved neurological outcome in experimental stroke.Jul 10, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cell Physiol Biochem. 2018 Jul 11 ;48(1):42-53. Epub 2018 Jul 11. PMID: 29996116
Article Published Date : Jul 10, 2018
Study Type : Animal Study
Additional Links
Substances : Alpha-Lipoic Acid
Diseases : Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Alpha-mangostin could be used to delay the progression of osteoarthritis.Oct 31, 2017

Pubmed Data : Int Immunopharmacol. 2017 Nov ;52:156-162. Epub 2017 Oct 12. PMID: 28915439
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Garcinia Mangostana
Diseases : Osteoarthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Alpha-tocopherol ameliorates redox equilibrium and reduces inflammatory response caused by chronic variable stress.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2018 ;2018:7210783. Epub 2018 Nov 8. PMID: 30533439
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin E: alpha tocopherol
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Amelioration of adjuvant induced arthritis in Sprague Dawley rats through modulation of inflammatory mediators by Ribes alpestre Decne.May 09, 2019

Pubmed Data : J Ethnopharmacol. 2019 May 10 ;235:460-471. Epub 2019 Feb 13. PMID: 30771518
Article Published Date : May 09, 2019
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-4 upregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Postaglandin PGE2 downregulation , Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Ameliorative effect of berberine on neonatally induced type 2 diabetic neuropathy.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dose Response. 2019 Jul-Sep;17(3):1559325819862449. Epub 2019 Jul 16. PMID: 31360147
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Amla fruit provides protection against arsenics induced inflammation and immunotoxicity.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Springerplus. 2015 ;4:438. Epub 2015 Aug 21. PMID: 26312203
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Amla Fruit
Diseases : Arsenic Poisoning, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Immunomodulatory, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Arsenic
[+]

Amygdalin isolated from Prunus armeniaca reduces pain in rats.Jul 31, 2008

Pubmed Data : Biol Pharm Bull. 2008 Aug ;31(8):1559-64. PMID: 18670089
Article Published Date : Jul 31, 2008
Study Type : Animal Study
Additional Links
Substances : Amygdalin
Diseases : Pain
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

An aqueous extract of I. obliquus might be a useful supplement in the setting of inflammatory bowel disease.Sep 27, 2012

Pubmed Data : J Ethnopharmacol. 2012 Sep 28 ;143(2):524-32. Epub 2012 Jul 20. PMID: 22819687
Article Published Date : Sep 27, 2012
Study Type : Animal Study
Additional Links
Substances : Chaga Mushroom (Inonotus obliquus)
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

An extract of Musa sapientum fruit showed antidiabetic and better ulcer healing effects compared with omeprazole.Nov 04, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2013 Nov 5 ;13:305. Epub 2013 Nov 5. PMID: 24192345
Article Published Date : Nov 04, 2013
Study Type : Animal Study
Additional Links
Substances : Banana
Diseases : Gastric Ulcer
Pharmacological Actions : Hypoglycemic Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

An extract of polymethoxyflavones from Billygoat weed exhibited significant antinociceptive and anti-inflammatory effects.Sep 11, 2016

Pubmed Data : J Ethnopharmacol. 2016 Sep 12. Epub 2016 Sep 12. PMID: 27633406
Article Published Date : Sep 11, 2016
Study Type : Animal Study
Additional Links
Substances : Billygoat Weed
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antinoceceptive , Interleukin-1 beta downregulation, Prostaglandin PGE2 downregulation
Additional Keywords : Plant Extracts
[+]

An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.Oct 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Nov ;95:1040-1050. Epub 2017 Sep 13. PMID: 28922721
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Stevia
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anthocyanin from Lonicera caerulea can be used as a dietary health supplement for alcoholic steatohepatitis.Jun 09, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Pharmacother. 2019 Jun 10 ;117:109087. Epub 2019 Jun 10. PMID: 31195351
Article Published Date : Jun 09, 2019
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Blue Honeysuckle
Diseases : Alcoholic Liver Disease
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation
[+]

Anthocyanin-rich fractions from red raspberries attenuate inflammation both in vitro and in vivo.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Sci Rep. 2014 ;4:6234. Epub 2014 Aug 29. PMID: 25167935
Article Published Date : Dec 31, 2013
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Anthocyanins, Raspberry
Diseases : Colitis, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Anti-glycative and anti-inflammatory effects of caffeic acid and ellagic acid in kidney of diabetic mice.Feb 28, 2010

Pubmed Data : Mol Nutr Food Res. 2010 Mar ;54(3):388-95. PMID: 19885845
Article Published Date : Feb 28, 2010
Study Type : Animal Study
Additional Links
Substances : Caffeic Acid, Ellagic Acid
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-hyperuricemic and anti-gouty arthritis activities of polysaccharide purified from Lonicera japonica.Feb 14, 2019

Pubmed Data : Int J Biol Macromol. 2019 Feb 15 ;123:801-809. Epub 2018 Nov 13. PMID: 30445085
Article Published Date : Feb 14, 2019
Study Type : Animal Study
Additional Links
Substances : Honeysuckle
Diseases : Hyperuricemia, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Uricosuric Agents
Additional Keywords : Polysaccharides
[+]

Anti-inflammatory activity of Chrysanthemum indicum extract in acute and chronic cutaneous inflammation.May 03, 2009

Pubmed Data : J Ethnopharmacol. 2009 May 4 ;123(1):149-54. Epub 2009 Feb 14. PMID: 19429354
Article Published Date : May 03, 2009
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Morifolium
Diseases : Dermatitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Anti-inflammatory activity of Rg3-enriched Korean red ginseng extract in murine model of sepsis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:6874692. Epub 2018 Oct 11. PMID: 30405742
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Ginseng (Korean)
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory and anti-arthritic effects of methanol extract of the stem bark of Boswellia dalzielii.Nov 30, 2018

Pubmed Data : Inflammopharmacology. 2018 Dec ;26(6):1383-1398. Epub 2018 Jun 13. PMID: 29948494
Article Published Date : Nov 30, 2018
Study Type : Animal Study
Additional Links
Substances : Frankincense
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction.Nov 14, 2016

Pubmed Data : Eur J Pharmacol. 2016 Nov 15 ;791:595-602. Epub 2016 Aug 26. PMID: 27568839
Article Published Date : Nov 14, 2016
Study Type : Animal Study
Additional Links
Substances : Ginger, Polyphenols
Diseases : Myocardial Infarction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.Apr 26, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Complement Altern Med. 2017 Apr 27 ;17(1):233. Epub 2017 Apr 27. PMID: 28449676
Article Published Date : Apr 26, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin, Ligustrazine, Resveratrol
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Anti-obesity effect of Lactobacillus rhamnosus LS-8 and Lactobacillus crustorum MN047 on high-fat and high-fructose diet.Oct 27, 2019

Pubmed Data : Eur J Nutr. 2019 Oct 28. Epub 2019 Oct 28. PMID: 31659451
Article Published Date : Oct 27, 2019
Study Type : Animal Study
Additional Links
Substances : Lactobacillus probiotics, Lactobacillus rhamnosus
Diseases : High Fat Diet, High Fructose Diet, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Obesity Agents
[+]

Antidepressant activity of crocin-I is associated with amelioration of neuroinflammation and attenuates oxidative damage induced by corticosterone.Oct 11, 2019

Pubmed Data : Physiol Behav. 2019 Oct 12 ;212:112699. Epub 2019 Oct 12. PMID: 31614158
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Brain Inflammation , Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Antioxidants, Interleukin-1 beta downregulation
[+]

Antidepressant effects of rosemary extracts associate with anti-inflammatory effect and rebalance of gut microbiota.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1126. Epub 2018 Oct 2. PMID: 30364169
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Rosemary
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Gastrointestinal Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antidepressant-like effect and mechanism of action of honokiol in lipopolysaccharide depression model.May 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 May 28 ;24(11). Epub 2019 May 28. PMID: 31141940
Article Published Date : May 27, 2019
Study Type : Animal Study
Additional Links
Substances : Honokiol
Diseases : Depression, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice.Apr 30, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Saudi J Biol Sci. 2018 May ;25(4):747-754. Epub 2016 Oct 13. PMID: 29740240
Article Published Date : Apr 30, 2018
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Liver Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antihypernociceptive and neuroprotective effects of Combretin A and Combretin B on streptozotocin-induced diabetic neuropathy.May 31, 2019

Pubmed Data : Naunyn Schmiedebergs Arch Pharmacol. 2019 Jun ;392(6):697-713. Epub 2019 Feb 13. PMID: 30759263
Article Published Date : May 31, 2019
Study Type : Animal Study
Additional Links
Substances : Combretum fragrans
Diseases : Diabetic Neuropathy
Pharmacological Actions : Anti-Anxiety Agents, Anti-Inflammatory Agents, Antidepressive Agents, Antinoceceptive , Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Neuroprotective Agents, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Antioxidant-rich extract from plantaginis semen Ameliorates diabetic retinal injury in a streptozotocin-induced diabetic rat model.Sep 17, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Nutrients. 2016 Sep 18 ;8(9). Epub 2016 Sep 18. PMID: 27649243
Article Published Date : Sep 17, 2016
Study Type : Animal Study
Additional Links
Substances : Plantago asiatica
Diseases : Diabetic Retinopathy
Pharmacological Actions : Antioxidants, Hypoxia inducible factor-1 alpha (HIF-1α) inhibitor, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Apigenin ameliorates HFD-induced NAFLD through regulation of the XO/NLRP3 pathways.Jun 13, 2019

Pubmed Data : J Nutr Biochem. 2019 Jun 14 ;71:110-121. Epub 2019 Jun 14. PMID: 31325892
Article Published Date : Jun 13, 2019
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation
[+]

Apigenin supplement might provide a basis for developing a new dietary strategy for the prevention of chronic ulcerative colitis.Mar 31, 2016

Pubmed Data : J Nutr Biochem. 2016 Apr ;30:143-52. Epub 2016 Jan 4. PMID: 27012631
Article Published Date : Mar 31, 2016
Study Type : Animal Study
Additional Links
Substances : Apigenin
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Apocynin has a protective role in a rat model of traumatic brain injury.Aug 06, 2017

Pubmed Data : Neurochem Res. 2017 Aug 7. Epub 2017 Aug 7. PMID: 28786047
Article Published Date : Aug 06, 2017
Study Type : Animal Study
Additional Links
Substances : Apocynin
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Apple polysaccharides exerts health benefits through inhibiting gut dysbiosis and chronic inflammation and modulating gut permeability.Feb 22, 2017

Pubmed Data : Int J Biol Macromol. 2017 Feb 23. Epub 2017 Feb 23. PMID: 28238909
Article Published Date : Feb 22, 2017
Study Type : Animal Study
Additional Links
Substances : Apples
Diseases : Dysbiosis, Gastrointestinal Inflammation, High Fat Diet
Pharmacological Actions : Gastrointestinal Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Polysaccharides
[+]

Arctigenin attenuates inflammation in DSS-induced acute colitis through suppression of NLRP3 inflammasome by SIRT1.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2019 ;11(7):3992-4009. Epub 2019 Jul 15. PMID: 31396314
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Arctigenin could protect the kidney from unilateral ureteral obstruction induced injury and fibrogenesis.Jun 30, 2017

Pubmed Data : Phytomedicine. 2017 Jul 1 ;30:28-41. Epub 2017 Mar 10. PMID: 28545667
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Kidney Fibrosis, Obstructive Nephropathy
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Arctigenin may confer protection against ischemic stroke.Nov 03, 2017

Pubmed Data : Biochem Biophys Res Commun. 2017 Nov 4 ;493(1):821-826. Epub 2017 Sep 6. PMID: 28888980
Article Published Date : Nov 03, 2017
Study Type : Animal Study
Additional Links
Substances : Arctigenin
Diseases : Stroke: Ischemic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Artesunate affords protection against aspirin-induced gastric injury.Mar 31, 2018

Pubmed Data : Pharmacol Rep. 2018 Apr ;70(2):390-397. Epub 2017 Jun 15. PMID: 29397336
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Artesunate
Diseases : Aspirin-Induced Toxicity , Gastric Ulcer, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Ulcer Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
Additional Keywords : Natural Substances Versus Drugs
Problem Substances : Aspirin
[+]

Asiatic acid may be a novel therapeutic agent for cardiac hypertrophy.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Thorac Dis. 2015 Oct ;7(10):1787-97. PMID: 26623102
Article Published Date : Sep 30, 2015
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Asiatic Acid
Diseases : Cardiac Hypertrophy
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
[+]

Astaxanthin could be a promising agent for atopic dermatitis by inhibition of NF-κB signalling.Sep 07, 2017

Pubmed Data : Exp Dermatol. 2017 Sep 8. Epub 2017 Sep 8. PMID: 28887839
Article Published Date : Sep 07, 2017
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners.Sep 18, 2018

Pubmed Data : J Nutr Biochem. 2018 Sep 19 ;62:202-209. Epub 2018 Sep 19. PMID: 30308382
Article Published Date : Sep 18, 2018
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astaxanthin
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Astaxanthin exerts different anti-inflammatory effects in female and male brains.Jan 29, 2016

Pubmed Data : J Sci Food Agric. 2016 Jan 30 ;96(2):615-8. Epub 2015 Feb 25. PMID: 25678261
Article Published Date : Jan 29, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Aging, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation
[+]

Astaxanthin had an anti-depressant effect on diabetic mice.Dec 21, 2016

Pubmed Data : Brain Res. 2016 Dec 22. Epub 2016 Dec 22. PMID: 28017669
Article Published Date : Dec 21, 2016
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Brain Inflammation , Depression, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Prophylactic Agents
[+]

Astaxanthin reduces the susceptibility to oxidation and potentizes the immunomodulatory properties of fish oil. Oct 05, 2011

Pubmed Data : Eur J Nutr. 2011 Oct 5. Epub 2011 Oct 5. PMID: 21972007
Article Published Date : Oct 05, 2011
Study Type : Animal Study
Additional Links
Substances : Astaxanthin, Fish Oil
Diseases : Oxidative Stress
Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation
Additional Keywords : Natural Substance Synergy
[+]

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo.Sep 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Oct ;18(4):2877-2884. Epub 2019 Aug 16. PMID: 31572532
Article Published Date : Sep 30, 2019
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Astragaloside
Diseases : Ulcerative Colitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV ameliorates neuroinflammation-induced depressive-like behaviors in mice.May 23, 2018

Pubmed Data : Acta Pharmacol Sin. 2018 May 24. Epub 2018 May 24. PMID: 29795356
Article Published Date : May 23, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Brain Inflammation , Depressive Disorder
Pharmacological Actions : Anti-Inflammatory Agents, Antidepressive Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV attenuates acetaminophen-induced liver injuries in mice.Aug 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Aug 14 ;23(8). Epub 2018 Aug 14. PMID: 30110942
Article Published Date : Aug 13, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Acetaminophen (Tylenol) Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Acetaminophen, Paracetamol
[+]

Astragaloside IV combats liver cirrhosis.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Jan ;17(1):393-397. Epub 2018 Nov 13. PMID: 30651810
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Liver Cirrhosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside IV might become a promising potential anti-inflammatory agent for endometritis and other inflammatory diseases.Jan 20, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Jan 21 ;24(2). Epub 2019 Jan 21. PMID: 30669661
Article Published Date : Jan 20, 2019
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Endometritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Astragaloside might be a useful chemical in improving the spatial memory and relieving the oxidative stress and neuroinflammation in Alzheimer patients.Mar 29, 2018

Pubmed Data : Chin Med Sci J. 2018 Mar 30 ;33(1):29-37. PMID: 29620512
Article Published Date : Mar 29, 2018
Study Type : Animal Study
Additional Links
Substances : Astragaloside
Diseases : Alzheimer's Disease, Brain: Oxidative Stress, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Atractylodes macrocephala polysaccharide has protective effects on liver ischemia-reperfusion injury.Dec 31, 2010

Pubmed Data : Am J Chin Med. 2011 ;39(3):489-502. PMID: 21598417
Article Published Date : Dec 31, 2010
Study Type : Animal Study
Additional Links
Substances : Bai Zhu
Diseases : Lipid Peroxidation, Liver Injury: Ischemia/reperfusion
Pharmacological Actions : Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Baicalein improves learning and memory dysfunction in D-gal induced aging rats.May 25, 2017

Pubmed Data : Rejuvenation Res. 2017 May 26. Epub 2017 May 26. PMID: 28548620
Article Published Date : May 25, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein
Diseases : Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Nitric Oxide Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation May 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Anat Cell Biol. 2017 Jun ;50(2):124-134. Epub 2017 Jun 27. PMID: 28713616
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : Baicalein, Chinese Skullcap , Wogonin
Diseases : Asthma
Pharmacological Actions : Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-4 downregulation, Interleukin-5 downregulation
[+]

Bamboo extracts could be useful in treating HIV driven brain inflammation. Apr 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J HIV AIDS. 2016 May ;2(3). Epub 2016 May 11. PMID: 27398410
Article Published Date : Apr 30, 2016
Study Type : Animal Study
Additional Links
Substances : Bamboo
Diseases : Brain Inflammation , HIV Infections
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Bee venom may be a useful therapeutic agent for the prevention of fibrosis that characterizes progression of chronic kidney disease.May 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Toxins (Basel). 2015 Jun ;7(6):1917-28. Epub 2015 May 29. PMID: 26035488
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Substances : Bee Venom
Diseases : Chronic Kidney Disease (CKD), Kidney Fibrosis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Berberine alleviates endothelial glycocalyx degradation and promotes glycocalyx restoration in LPS-induced ARDS.Oct 07, 2018

Pubmed Data : Int Immunopharmacol. 2018 Oct 8 ;65:96-107. Epub 2018 Oct 8. PMID: 30308440
Article Published Date : Oct 07, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Acute Respiratory Distress Syndrome, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine attenuates macrophages infiltration in intracranial aneurysms. Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:565. Epub 2018 May 30. PMID: 29899701
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Aneurysm: Cerebral
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine can reverse chronic inflammatory pain induced by complete freund's adjuvant and alleviated the comorbid depression.Apr 09, 2018

Pubmed Data : Zhonghua Yi Xue Za Zhi. 2018 Apr 10 ;98(14):1103-1108. PMID: 29690724
Article Published Date : Apr 09, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Depression, Hyperalgesia, Inflammation
Pharmacological Actions : Analgesics, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine could alleviate postoperative cognitive dysfunction by suppressing neuroinflammation in aged mice.Jun 30, 2016

Pubmed Data : Int Immunopharmacol. 2016 Jul 1 ;38:426-433. Epub 2016 Jul 1. PMID: 27376853
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction, Postoperative Recovery
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine could generate an anti-osteosarcoma property through downregulating caspase-1/IL-1β inflammatory signaling axis.Jan 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncol Rep. 2017 Feb ;37(2):729-736. Epub 2016 Dec 16. PMID: 28000894
Article Published Date : Jan 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Berberine
Diseases : Osteosarcoma
Pharmacological Actions : Antiproliferative , Interleukin-1 beta downregulation
[+]

Berberine has anti-inflammatory effects on H. pylori-induced chronic gastritis.Jan 17, 2018

Pubmed Data : J Cell Biochem. 2018 Jan 18. Epub 2018 Jan 18. PMID: 29345340
Article Published Date : Jan 17, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Helicobacter Pylori Infection
Pharmacological Actions : Anti-Inflammatory Agents, Immunomodulatory: Th17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Berberine hydrochloride can provide mice robust protection from LPS-induced mastitis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2018 ;2018:5164314. Epub 2018 Apr 15. PMID: 29849710
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Lipopolysaccharide-Induced Toxicity, Mastitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.Aug 06, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : World J Gastroenterol. 2019 Aug 7 ;25(29):3956-3971. PMID: 31413530
Article Published Date : Aug 06, 2019
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Berberine protects against gastrointestinal injuries from alcohol stress.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2015 ;10(7):e0134044. Epub 2015 Jul 30. PMID: 26226164
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Alcohol Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Gastroprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine reduces neuroglia activation and inflammation in streptozotocin-induced diabetic mice.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419866379. PMID: 31337260
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Berberine treatment reduced hepatic injury caused by concanavalin A.Dec 27, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2017 Dec 28 ;23:6150-6161. Epub 2017 Dec 28. PMID: 29283990
Article Published Date : Dec 27, 2017
Study Type : Animal Study
Additional Links
Substances : Berberine
Diseases : Hepatitis: Autoimmune
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Berberine, Hepatitis: Autoimmune, Hepatoprotective, Interferon Gamma Reducer
Problem Substances : Concanavalin A
[+]

Beta-caryophyllene alleviates ischemic brain damage potentially by inhibiting necroptotic neuronal death and inflammatory response.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Neurosci. 2017 ;11:583. Epub 2017 Oct 26. PMID: 29123466
Article Published Date : Dec 31, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Beta-caryophyllene constitutes an alluring therapeutic molecule towards the treatment of multiple sclerosis.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2017 Apr 1 ;18(4). Epub 2017 Apr 1. PMID: 28368293
Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Beta-Caryophyllene
Diseases : Inflammation: Brain, Multiple Sclerosis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Immunomodulatory, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Cannabinoid Receptors
[+]

Betulinic acid derivative BA5 had a potent anti-inflammatory activity on a model of parasite-driven heart disease.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Immunol. 2019 ;10:1257. Epub 2019 Jun 11. PMID: 31244833
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Diseases : Chagas Disease, Fibrosis
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Cardioprotective, Interferon Gamma Reducer, Interleukin-10 upregulation, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Betulinic acid protects the neuronal damage in new born rats from isoflurane-induced apoptosis in the developing brain.Oct 31, 2017

Pubmed Data : Biomed Pharmacother. 2017 Nov ;95:1631-1635. Epub 2017 Oct 6. PMID: 28950663
Article Published Date : Oct 31, 2017
Study Type : Animal Study
Additional Links
Substances : Betulinic acid
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Bilobalide exerted a gastro-protective effect against gastric ulceration.Nov 26, 2016

Pubmed Data : Biomed Pharmacother. 2016 Nov 27. Epub 2016 Nov 27. PMID: 27903426
Article Published Date : Nov 26, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginkgo biloba
Diseases : Gastric Ulcer
Pharmacological Actions : Gastroprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A exerts protective effects on lipopolysaccharide-induced Parkinson's disease.Jan 09, 2016

Pubmed Data : Neurotox Res. 2016 10 ;30(3):486-98. Epub 2016 Jul 14. PMID: 27417698
Article Published Date : Jan 09, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Biochanin A
Diseases : Lipopolysaccharide-Induced Toxicity, Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A has been shown to have neuroprotective effects in cerebral ischemia/reperfusion.Jan 14, 2015

Pubmed Data : J Neurol Sci. 2015 Jan 15 ;348(1-2):121-5. Epub 2014 Nov 18. PMID: 25466482
Article Published Date : Jan 14, 2015
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Brain Inflammation , Brain Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.Aug 31, 2016

Pubmed Data : Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID: 27344638
Article Published Date : Aug 31, 2016
Study Type : Animal Study
Additional Links
Substances : Biochanin A
Diseases : Chemically-Induced Liver Damage, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Nrf2 activation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Black cumin oil decreased the proinflammatory cytokines, lactate dehydrogenase, triglyceride, and cholesterol, which were increased in colitis.Feb 28, 2011

Pubmed Data : Dig Dis Sci. 2011 Mar ;56(3):721-30. Epub 2010 Jul 24. PMID: 20658190
Article Published Date : Feb 28, 2011
Study Type : Animal Study
Additional Links
Substances : Nigella sativa (aka Black Seed)
Diseases : Oxidative Stress, Ulcerative Colitis
Pharmacological Actions : Antioxidants, Hypolipidemic, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Oils
[+]

Black ginseng-enriched Chong-Myung-Tang extracts improve spatial learning behavior.Mar 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ginseng Res. 2017 Apr ;41(2):151-158. Epub 2016 Mar 25. PMID: 28413319
Article Published Date : Mar 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Ginseng
Diseases : Memory Disorders
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

Black rice anthocyanin-rich extract and rosmarinic acid may provide a promising dietary approach for the management of inflammatory bowel disease.May 22, 2018

Pubmed Data : Food Funct. 2018 May 23 ;9(5):2796-2808. PMID: 29691532
Article Published Date : May 22, 2018
Study Type : Animal Study
Additional Links
Substances : Anthocyanins, Brown Rice, Rosmarinic acid
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Blackcurrant prevents obesity-induced nonalcoholic steatohepatitis in mice.Dec 31, 2018

Pubmed Data : Obesity (Silver Spring). 2019 Jan ;27(1):112-120. PMID: 30569636
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Black Currant
Diseases : Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation.Dec 12, 2018

Pubmed Data : Proc Natl Acad Sci U S A. 2018 Dec 13. Epub 2018 Dec 13. PMID: 30545915
Article Published Date : Dec 12, 2018
Study Type : Animal Study
Additional Links
Diseases : Breast Cancer, Inflammation
Pharmacological Actions : Chemotherapeutic, Interleukin-1 beta downregulation
[+]

Blueberry extract had a preventive and therapeutic effect against DSS-induced ulcerative colitis in mice.Jan 31, 2016

Pubmed Data : J Nutr Biochem. 2016 Feb ;28:103-13. Epub 2015 Oct 26. PMID: 26878787
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Blueberry
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor
Additional Keywords : Plant Extracts
[+]

Boron protects against bisphenol-A induced oxidative stress, inflammatory gene expression, and metabolic and histopathological changes.Feb 28, 2019

Pubmed Data : Toxicol Res (Camb). 2019 Mar 1 ;8(2):262-269. Epub 2019 Jan 23. PMID: 30997025
Article Published Date : Feb 28, 2019
Study Type : Animal Study
Additional Links
Substances : Boron
Diseases : Bisphenol Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Bisphenol A
[+]

Brazilian green propolis prevents cognitive decline into mild cognitive impairment in elderly people living at high altitude.Dec 31, 2017

Pubmed Data : J Alzheimers Dis. 2018 ;63(2):551-560. PMID: 29630549
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Propolis: Brazillian
Diseases : Brain Inflammation , Cognitive Decline/Dysfunction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

C. officinalis can be a potential therapeutical adjuvant in the treatment of periodontitis.Jun 30, 2018

Pubmed Data : Clin Oral Investig. 2018 Jul ;22(6):2175-2185. Epub 2017 Dec 29. PMID: 29288400
Article Published Date : Jun 30, 2018
Study Type : Animal Study
Additional Links
Substances : Marigold
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Cabbage extracts have a pancreato-protective effect.Jan 19, 2017

Pubmed Data : Nat Prod Res. 2017 Jan 20:1-4. Epub 2017 Jan 20. PMID: 28107794
Article Published Date : Jan 19, 2017
Study Type : Animal Study
Additional Links
Substances : Cabbage
Diseases : Alcohol Toxicity , Pancreatitis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-18 down-regulation, Interleukin-1 beta downregulation, Pancreato Protective Agents
Additional Keywords : Alcohol Toxicity, Anti-Inflammatory Agents, Antioxidants, Cabbage, Pancreatitis, Plant Extracts
[+]

Camel milk inhibits inflammatory angiogenesis via downregulation of proangiogenic and proinflammatory cytokines in mice.Jun 30, 2014

Pubmed Data : APMIS. 2014 Jul ;122(7):599-607. Epub 2013 Dec 10. PMID: 24320686
Article Published Date : Jun 30, 2014
Study Type : Animal Study
Additional Links
Substances : Camel Milk
Diseases : Cancers: All, Inflammation
Pharmacological Actions : Anti-Angiogenic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor, Vascular Endothelial Growth Factor Inhibitors
[+]

Cannabichromene could be considered for clinical experimentation in inflammatory bowel disease patients.Apr 30, 2013

Pubmed Data : Biochem Pharmacol. 2013 May 1 ;85(9):1306-16. Epub 2013 Feb 12. PMID: 23415610
Article Published Date : Apr 30, 2013
Study Type : Animal Study
Additional Links
Substances : Cannabigerol , Cannabinoids
Diseases : Colitis, Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Nitric Oxide Inhibitor, Superoxide Dismutase Up-regulation
[+]

Cannabidiol could be used to prevent experimental colitis in mice.Oct 31, 2009

Pubmed Data : J Mol Med (Berl). 2009 Nov ;87(11):1111-21. Epub 2009 Aug 20. PMID: 19690824
Article Published Date : Oct 31, 2009
Study Type : Animal Study
Additional Links
Substances : Cannabidiol, Cannabis
Diseases : Colitis
Pharmacological Actions : Antioxidants, Cyclooxygenase 2 Inhibitors, Interleukin-10 downregulation, Interleukin-1 beta downregulation
[+]

Cardioprotective effects of puerarin-V on isoproterenol-induced myocardial infarction.Dec 13, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2018 Dec 14 ;23(12). Epub 2018 Dec 14. PMID: 30558188
Article Published Date : Dec 13, 2018
Study Type : Animal Study
Additional Links
Substances : Puerarin
Diseases : Myocardial Infarction
Pharmacological Actions : Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Isoproterenol
[+]

Carnosic acid may represent a novel therapeutic strategy to treat metabolic disease induced brain injury.Jun 30, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2019 Jul ;20(1):495-504. Epub 2019 May 27. PMID: 31180544
Article Published Date : Jun 30, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Brain Inflammation , High Fat Diet
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents
[+]

Carnosic acid protects against lipopolysaccharide-induced acute lung injury in mice.Oct 31, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Exp Ther Med. 2019 Nov ;18(5):3707-3714. Epub 2019 Sep 23. PMID: 31611929
Article Published Date : Oct 31, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosic Acid
Diseases : Lipopolysaccharide-Induced Toxicity, Lung Injury: Acute
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Carnosine prevents Aβ-induced oxidative stress and inflammation in microglial cells.Jan 16, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cells. 2019 Jan 17 ;8(1). Epub 2019 Jan 17. PMID: 30658430
Article Published Date : Jan 16, 2019
Study Type : Animal Study
Additional Links
Substances : Carnosine
Diseases : Alzheimer's Disease, Brain Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents
[+]

CBD may be useful to control bone resorption during progression of experimental periodontitis in rats.Jan 31, 2009

Pubmed Data : Int Immunopharmacol. 2009 Feb ;9(2):216-22. Epub 2008 Dec 12. PMID: 19070683
Article Published Date : Jan 31, 2009
Study Type : Animal Study
Additional Links
Substances : Cannabidiol
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Centella asiatica enhances hepatic antioxidant status and regulates hepatic inflammatory cytokines in type 2 diabetic rats.Nov 30, 2017

Pubmed Data : Pharm Biol. 2017 Dec ;55(1):1671-1678. PMID: 28447512
Article Published Date : Nov 30, 2017
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Diabetes Mellitus: Type 2, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Malondialdehyde Down-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Centella asiatica may be useful in preventing liver damage.Oct 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2016 Nov ;14(5):4521-4528. Epub 2016 Oct 5. PMID: 27748812
Article Published Date : Oct 31, 2016
Study Type : Animal Study
Additional Links
Substances : Gotu Kola
Diseases : Chemically-Induced Liver Damage, Inflammation, Oxidative Stress
Pharmacological Actions : Antioxidants, Interleukin-10 downregulation, Interleukin-12 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Superoxide Dismutase Up-regulation
[+]

Chamaecyparis obtusa essential oil has anti-inflammatory and anti-nociceptive effects on arthritis in rats.Dec 31, 2014

Pubmed Data : Biosci Biotechnol Biochem. 2015 ;80(1):203-9. Epub 2015 Aug 19. PMID: 26581235
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Japanese cypress
Diseases : Arthritis
Pharmacological Actions : Analgesics, Anti-Inflammatory Agents, Antinoceceptive , Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Essential Oils
[+]

Chamomile methanolic extract mitigates small bowel inflammation and ROS overload related to the intestinal nematodes infection.Jan 21, 2019

Pubmed Data : Acta Parasitol. 2019 Jan 22. Epub 2019 Jan 22. PMID: 30671769
Article Published Date : Jan 21, 2019
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Gastrointestinal Inflammation, Parasitic Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Chamomile prevented inflammation and alveolar bone resorption in animals.Jan 15, 2016

Pubmed Data : J Periodontol. 2016 Jan 16:1-17. Epub 2016 Jan 16. PMID: 26777767
Article Published Date : Jan 15, 2016
Study Type : Animal Study
Additional Links
Substances : Chamomile
Diseases : Periodontitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

chia consumption decreased the concentrations of the inflammatory markers IL-1β and LDL-c.Jul 16, 2019

Pubmed Data : Food Funct. 2019 Jul 17 ;10(7):4036-4045. PMID: 31219482
Article Published Date : Jul 16, 2019
Study Type : Animal Study
Additional Links
Substances : Chia
Diseases : Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Ovariectomy-Induced Changes
[+]

Chilean white strawberry aqueous extract favours the normalization of oxidative and inflammatory responses after a liver injury induced by LPS.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Evid Based Complement Alternat Med. 2015 ;2015:320136. Epub 2015 Sep 17. PMID: 26457108
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Strawberry
Diseases : Lipopolysaccharide-Induced Toxicity, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Chinese skullcap (Scutellaria baicalensis) significantly improves functional recovery from spinal cord injury in rats by inhibiting inflammation and oxidative stress after injury.Aug 01, 2009

Pubmed Data : J Neurochem. 2009 Aug;110(4):1276-87. Epub 2009 Jun 10. PMID: 19519665
Article Published Date : Aug 01, 2009
Study Type : Animal Study
Additional Links
Substances : Chinese Skullcap
Diseases : Brain: Microglial Activation, Spinal Cord Injuries
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Apoptotic, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Nitric Oxide Inhibitor
Additional Keywords : Plant Extracts
[+]

Chlorella vulgaris extract may have potential as a nutraceutical ingredient for the prevention of atopic dermatitis.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2015 ;16(9):21021-34. Epub 2015 Sep 2. PMID: 26404252
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Chlorella (Algae)
Diseases : Atopic Dermatitis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-4 downregulation
Additional Keywords : Plant Extracts
[+]

Chrysanthemum indicum demonstrates a beneficial role in preventing inflammation and the effects of oxidative stress.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:8206281. Epub 2017 Feb 2. PMID: 28261616
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Spondylitis: Ankylosing
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Catalase Up-Regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Superoxide Dismutase Up-regulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Chrysanthemum indicum has a protective effect on acute lung injury induced by lipopolysaccharide.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mediators Inflamm. 2014 ;2014:246407. Epub 2014 Aug 25. PMID: 25214712
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Plant Extracts
[+]

Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseasesJan 01, 2019

Pubmed Data : J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID: 30610932
Article Published Date : Jan 01, 2019
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Aging: Brain , Brain Inflammation , Liver Damage
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Chrysanthemum indicum was a novel photo-protective agent from natural resources against UV irradiation.Sep 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Rejuvenation Res. 2015 Oct ;18(5):437-48. Epub 2015 Aug 20. PMID: 25849065
Article Published Date : Sep 30, 2015
Study Type : Animal Study
Additional Links
Substances : Chrysanthemum Indicum
Diseases : Aging Skin, Oxidative Stress, Ultraviolet Radiation Induced Damage
Therapeutic Actions : Sunlight exposure
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-10 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Photoprotective
Additional Keywords : Plant Extracts
[+]

Cinnamaldehyde co-administration prevented HFD-induced body weight gain, and decreased fasting-induced hyperphagia.Feb 29, 2016

Pubmed Data : Biofactors. 2016 Mar-Apr;42(2):201-11. Epub 2016 Feb 19. PMID: 26893251
Article Published Date : Feb 29, 2016
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cinnamaldehyde
Diseases : High Fat Diet, Inflammation, Obesity
Therapeutic Actions : Fasting/Caloric Restriction
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
Additional Keywords : Anti-Obesity Agents
[+]

Cinnamaldehyde has a protective effect in the endotoxin poisoned mice through the inhibition of NLRP3 inflammasome activation.Sep 30, 2017

Pubmed Data : Immunopharmacol Immunotoxicol. 2017 Oct ;39(5):296-304. Epub 2017 Aug 1. PMID: 28762847
Article Published Date : Sep 30, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Cinnamaldehyde
Diseases : Endotoxemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Coenzyme Q10 showed protective effects in sepsis.May 10, 2017

Pubmed Data : Biomed Pharmacother. 2017 May 11 ;91:912-919. Epub 2017 May 11. PMID: 28501779
Article Published Date : May 10, 2017
Study Type : Animal Study
Additional Links
Substances : Coenzyme Q10
Diseases : Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Combined treatment of curcumin with low doses of prednisolone may find therapeutic use in arthritis.Dec 31, 2013

Pubmed Data : J Pharm Pharmacol. 2014 Jan ;66(1):133-44. Epub 2013 Oct 21. PMID: 24138213
Article Published Date : Dec 31, 2013
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Natural Substance/Drug Synergy, Plant Extracts
[+]

Components of Astragalus and Panax notoginseng could strengthen the protective effects on cerebral ischemia injury.Dec 31, 2014

Pubmed Data : Am J Chin Med. 2015 ;43(7):1419-38. Epub 2015 Oct 18. PMID: 26477799
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Astragalus, Ginsenosides, Panax Notoginseng
Diseases : Brain Ischemia, Inflammation
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Neuroprotective Agents, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy
[+]

Cordyceps militaris polysaccharides exerted protective effects on diabetic nephropathy in mice via regulation of autophagy.Jul 31, 2019

Pubmed Data : Food Funct. 2019 Aug 1 ;10(8):5102-5114. Epub 2019 Jul 31. PMID: 31363726
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Inflammatory Agents, Autophagy Up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
Additional Keywords : Polysaccharides
[+]

Cordyceps militaris protected against chronic kidney disease progression.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oxid Med Cell Longev. 2019 ;2019:7850863. Epub 2019 Mar 31. PMID: 31049139
Article Published Date : Dec 31, 2018
Study Type : Animal Study
Additional Links
Substances : Cordyceps Militaris
Diseases : Chronic Kidney Disease (CKD)
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Crocetin supplementation in the MCA mice also showed protection against cervical cancer. Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2015 ;2015:829513. Epub 2015 Mar 22. PMID: 25874230
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Crocetin
Diseases : Cervical Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Crocetin was an effective agent in attenuating the adjuvant-induced arthritis rats in a concentration-dependent manner.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Front Pharmacol. 2018 ;9:1341. Epub 2018 Dec 12. PMID: 30618728
Article Published Date : Dec 31, 2017
Study Type : Animal Study, In Vitro Study
Additional Links
Substances : Crocetin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Heme oxygenase-1 up-regulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor, Nrf2 activation
Additional Keywords : Dose Response
[+]

Crocin ameliorates methotrexate-induced liver injury via inhibition of oxidative stress and inflammation.Jul 31, 2019

Pubmed Data : Pharmacol Rep. 2019 Aug ;71(4):746-752. Epub 2019 Apr 16. PMID: 31220735
Article Published Date : Jul 31, 2019
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Drug Toxicity: Methotrexate, Inflammation, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Methotrexate
[+]

Crocin could contribute to the development of phytotherapeutic approaches in the treatment of obesity and diabetes.Nov 16, 2016

Pubmed Data : Turk J Med Sci. 2016 Nov 17 ;46(5):1593-1602. Epub 2016 Nov 17. PMID: 27966333
Article Published Date : Nov 16, 2016
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Diabetes Mellitus: Type 2, Obesity
Pharmacological Actions : Anti-Inflammatory Agents, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Crocin may exert potent anti- rheumatoid arthritis effects through inhibiting cytokines.Apr 30, 2017

Pubmed Data : Biosci Biotechnol Biochem. 2017 May ;81(5):891-898. PMID: 28388359
Article Published Date : Apr 30, 2017
Study Type : Animal Study
Additional Links
Substances : Crocin
Diseases : Inflammation, Rheumatoid Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin alleviates dystrophic muscle pathology in mdx mice.Jun 30, 2008

Pubmed Data : Mol Cells. 2008 Jun 30;25(4):531-7. Epub 2008 May 6. PMID: 18460899
Article Published Date : Jun 30, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Duchenne's Muscular Dystrophy, Muscular Dystrophies
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin ameliorated skeletal muscle atrophy in DM mice by inhibiting protein ubiquitination, inflammatory cytokines and oxidative stress.May 21, 2015

Pubmed Data : Exp Physiol. 2015 May 22. Epub 2015 May 22. PMID: 25998196
Article Published Date : May 21, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetes: Oxidative Stress, Diabetes Mellitus: Type 1, Inflammation, Muscle Atrophy
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Significant Treatment Outcome
[+]

Curcumin and piperine afforded a better neuroprotective effect compared to each of them alone.Nov 15, 2016

Pubmed Data : Inflammopharmacology. 2016 Nov 16. Epub 2016 Nov 16. PMID: 27853890
Article Published Date : Nov 15, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin, Piperine
Diseases : Brain Inflammation , Parkinson's Disease
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Anti-Inflammatory Agents, Brain Inflammation, CURCUMIN, Interleukin-1 beta downregulation, Natural Substance Synergy, Parkinson's disease, Piperine
[+]

Curcumin and resveratrol regulate intestinal bacteria and alleviate intestinal inflammation.Mar 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Molecules. 2019 Mar 28 ;24(7). Epub 2019 Mar 28. PMID: 30925757
Article Published Date : Mar 27, 2019
Study Type : Animal Study
Additional Links
Substances : Curcumin, Resveratrol
Diseases : Gastrointestinal Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin attenuates the inflammatory response in collagen-induced arthritis. May 01, 2010

Pubmed Data : Int Immunopharmacol. 2010 May;10(5):605-10. Epub 2010 Feb 23. PMID: 20188213
Article Published Date : May 01, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Arthritis
Pharmacological Actions : Anti-Inflammatory Agents, Antiproliferative , Interleukin-1 beta downregulation
[+]

Curcumin has potent therapeutic activity in the amelioration of alcoholic neuropathy in rats. Jan 16, 2012

Pubmed Data : Neurosci Lett. 2012 Jan 16. Epub 2012 Jan 16. PMID: 22281447
Article Published Date : Jan 16, 2012
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Neuropathy: Alcoholic
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin Inhibits Imiquimod-Induced Psoriasis-Like Inflammation by Inhibiting IL-1beta and IL-6 Production in Mice.Dec 31, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : PLoS One. 2013 ;8(6):e67078. Epub 2013 Jun 25. PMID: 23825622
Article Published Date : Dec 31, 2012
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Psoriasis
Pharmacological Actions : Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Curcumin inhibits the increase of glutamate, hydroxyl radicals and PGE2 in the hypothalamus and reduces fever during LPS-induced systemic inflammation in rabbits.Sep 28, 2008

Pubmed Data : Eur J Pharmacol. 2008 Sep 28;593(1-3):105-11. Epub 2008 Jul 15. PMID: 18664365
Article Published Date : Sep 28, 2008
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Fever, Inflammation, Lipopolysaccharide-Induced Toxicity
Pharmacological Actions : Anti-pyretic , Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin is a potent antifibrotic agent and a promising treatment for diabetic nephropathy.Dec 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Biomed Res Int. 2017 ;2017:1516985. Epub 2017 Jan 17. PMID: 28194406
Article Published Date : Dec 31, 2016
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Diabetic Nephropathy
Pharmacological Actions : Anti-Fibrotic, Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Renoprotective
[+]

Curcumin nanoparticles attenuate cardiac remodeling due to pulmonary arterial hypertension..Dec 02, 2015

Pubmed Data : Artif Cells Nanomed Biotechnol. 2015 Dec 3:1-8. Epub 2015 Dec 3. PMID: 26631548
Article Published Date : Dec 02, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Hypertension: Arterial
Pharmacological Actions : Cardioprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin protects against intestinal origin endotoxemia in rat liver cirrhosis.Feb 13, 2017

Pubmed Data : J Food Sci. 2017 Feb 14. Epub 2017 Feb 14. PMID: 28196290
Article Published Date : Feb 13, 2017
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Chemically-Induced Liver Damage, Liver Cirrhosis
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Gene Expression Regulation
[+]

Curcumin protects effects against cerebral I/R injury through the activation of JAK2/STAT3 signaling pathway.Dec 31, 2014

Pubmed Data : Int J Clin Exp Med. 2015;8(9):14985-14991. Epub 2015 Sep 15. PMID: 26628981
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Cerebral Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-8 downregulation, Neuroprotective Agents
[+]

Curcumin reduces intestinal inflammation and polyps, indicating its potential value for preventing colon cancer.Oct 15, 2010

Pubmed Data : J Interferon Cytokine Res. 2010 Oct 15. Epub 2010 Oct 15. PMID: 20950131
Article Published Date : Oct 15, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Colon Cancer, Gastrointestinal Inflammation, Intestinal Cancer, Intestinal Polyps
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin reduces periductal fibrosis in liver fluke-infected in hamsters.Jul 25, 2010

Pubmed Data : Eur J Pharmacol. 2010 Jul 25;638(1-3):134-41. Epub 2010 Apr 24. PMID: 20420820
Article Published Date : Jul 25, 2010
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Flukes, Inflammation
Pharmacological Actions : Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin relieves a depressive-like state through the inhibition of the NLRP3 inflammasome and kynurenine pathway.Dec 09, 2018

Pubmed Data : Int Immunopharmacol. 2018 Dec 10 ;67:138-144. Epub 2018 Dec 10. PMID: 30551030
Article Published Date : Dec 09, 2018
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Depression
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Curcumin was effective in restoring the histopathological changes induced by acetic acid administration.Dec 31, 2014

Pubmed Data : J Environ Pathol Toxicol Oncol. 2015;34(4):309-320. PMID: 26756424
Article Published Date : Dec 31, 2014
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Inflammatory Bowel Diseases
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances : Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
[+]

Curcumin was found to have anti-hyperalgesic activity by decreasing oxidative stress and down regulation of inflammatory cytokines. Feb 28, 2015

Pubmed Data : Neurochem Res. 2015 Mar ;40(3):463-72. Epub 2014 Dec 6. PMID: 25479948
Article Published Date : Feb 28, 2015
Study Type : Animal Study
Additional Links
Substances : Curcumin
Diseases : Hyperalgesia, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Antioxidants, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cyanidin-3-glucoside inhibits inflammatory activities in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis.Jan 09, 2018

Pubmed Data : Clin Exp Pharmacol Physiol. 2018 10 ;45(10):1038-1045. Epub 2018 Jun 21. PMID: 29779214
Article Published Date : Jan 09, 2018
Study Type : Animal Study
Additional Links
Substances : Cyanidin 3-glucoside
Diseases : Arthritis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cyanidin-3-O-glucoside exerts pulmonary protective effects on CLP-induced ALI rats. Jun 11, 2015

Pubmed Data : J Surg Res. 2015 Jun 12. Epub 2015 Jun 12. PMID: 26152793
Article Published Date : Jun 11, 2015
Study Type : Animal Study
Additional Links
Substances : Cyanidin 3-glucoside
Diseases : Lung Injury: Acute, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Malondialdehyde Down-regulation, Mitochondrial Superoxide Dismutase Upregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Cystine and theanine improve survival after gut ischemia-reperfusion.Dec 31, 2017

Pubmed Data : Ann Nutr Metab. 2018 ;73(2):131-137. Epub 2018 Jul 27. PMID: 30056446
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Cystine, Theanine
Diseases : Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Daidzein attenuates abdominal aortic aneurysm through NF-κB, p38MAPK and TGF-β1 pathways.Jun 30, 2016

Pubmed Data : Mol Med Rep. 2016 Jul ;14(1):955-62. Epub 2016 May 18. PMID: 27222119
Article Published Date : Jun 30, 2016
Study Type : Animal Study
Additional Links
Substances : Daidzein, Isoflavones
Diseases : Aneurysm: Aortic
Pharmacological Actions : Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury.Jul 30, 2018

Pubmed Data : Food Chem Toxicol. 2018 Jul 31 ;120:500-509. Epub 2018 Jul 31. PMID: 30075314
Article Published Date : Jul 30, 2018
Study Type : Animal Study
Additional Links
Substances : Diallyl sulfide
Diseases : Lipopolysaccharide-Induced Toxicity, Liver Damage
Pharmacological Actions : Anti-Apoptotic, Anti-Inflammatory Agents, Antioxidants, Hepatoprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diallyl sulfide reduced the bleomycin-induced activation of inducible nitric oxide synthase (iNOS) and nuclear factor kappa-B (NF-kappaB) and decreased the augmented levels of the early inflammatory cytokines, tumour necrosis factor-alpha (TNF-alpha) and Jun 06, 2008

Pubmed Data : Life Sci. 2008 Jun 6;82(23-24):1142-53. Epub 2008 Apr 4. PMID: 18462759
Article Published Date : Jun 06, 2008
Study Type : Animal Study
Additional Links
Substances : Garlic
Diseases : Pulmonary Fibrosis
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice.May 20, 2011

Pubmed Data : Chem Biol Interact. 2011 May 20. Epub 2011 May 20. PMID: 21621527
Article Published Date : May 20, 2011
Study Type : Animal Study
Additional Links
Substances : Astaxanthin
Diseases : Colitis, Colon Cancer
Pharmacological Actions : Chemopreventive, Cyclooxygenase 2 Inhibitors, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, NF-kappaB Inhibitor
[+]

Dietary feeding of freeze-dried whole cranberry inhibits intestinal tumor development.Nov 16, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Oncotarget. 2017 Nov 17 ;8(58):97787-97800. Epub 2017 Oct 26. PMID: 29228651
Article Published Date : Nov 16, 2017
Study Type : Animal Study
Additional Links
Substances : Cranberry
Diseases : Colorectal Cancer
Pharmacological Actions : Anti-Inflammatory Agents, Chemopreventive, Interferon Gamma Reducer, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary intake of ascorbic acid attenuates lipopolysaccharide-induced sepsis and septic inflammation.Dec 31, 2017

Pubmed Data : J Nutr Sci Vitaminol (Tokyo). 2018 ;64(6):404-411. PMID: 30606963
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Vitamin C
Diseases : Inflammation, Lipopolysaccharide-Induced Toxicity, Sepsis
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Dietary red raspberries attenuate dextran sulfate sodium-induced acute colitis.Dec 31, 2017

Pubmed Data : J Nutr Biochem. 2018 01 ;51:40-46. Epub 2017 Sep 14. PMID: 29091813
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Raspberry
Diseases : Colitis, Oxidative Stress
Pharmacological Actions : Anti-Inflammatory Agents, Cyclooxygenase 2 Inhibitors, Interleukin-17 downregulation, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diets enriched with cranberry beans alter the microbiota and mitigate colitis severity and associated inflammation.Jan 31, 2016

Pubmed Data : J Nutr Biochem. 2016 Feb ;28:129-39. Epub 2015 Nov 4. PMID: 26878790
Article Published Date : Jan 31, 2016
Study Type : Animal Study
Additional Links
Substances : Common bean, Cranberry
Diseases : Colitis, Inflammation
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Differential effect of dandelion root extract on hepatic and testicular tissues of rats exposed to ionizing radiation.Jun 27, 2019

Pubmed Data : Mol Biol Rep. 2019 Jun 28. Epub 2019 Jun 28. PMID: 31254243
Article Published Date : Jun 27, 2019
Study Type : Animal Study
Additional Links
Substances : Dandelion
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Radioprotective, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Anti Therapeutic Actions : Radation Exposure: Low-Dose
[+]

Diosgenin attenuates inflammatory response induced by myocardial reperfusion injury.May 31, 2014

Pubmed Data : J Physiol Biochem. 2014 Jun ;70(2):425-32. Epub 2014 Feb 18. PMID: 24535716
Article Published Date : May 31, 2014
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Inflammation, Myocardial Ischemia
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diosgenin attenuates neuropathic pain in a rat model of chronic constriction injury.Jul 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Mol Med Rep. 2017 Aug ;16(2):1559-1564. Epub 2017 Jun 8. PMID: 29067449
Article Published Date : Jul 31, 2017
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Hyperalgesia, Oxidative Stress
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Diosgenin glucoside protects against myocardial injury in diabetic mice.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Am J Transl Res. 2018 ;10(11):3742-3749. Epub 2018 Nov 15. PMID: 30662624
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Diabetes Mellitus: Type 2, Diabetic Complications
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation
[+]

Diosgenin protects rats from myocardial inflammatory injury induced by ischemia-reperfusion.Jan 11, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Med Sci Monit. 2018 Jan 12 ;24:246-253. Epub 2018 Jan 12. PMID: 29329279
Article Published Date : Jan 11, 2018
Study Type : Animal Study
Additional Links
Substances : Diosgenin
Diseases : Inflammation, Ischemia
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Early hyperbaric oxygen treatment attenuates burn-induced neuro-inflammation.Jul 26, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Mol Sci. 2018 Jul 27 ;19(8). Epub 2018 Jul 27. PMID: 30060489
Article Published Date : Jul 26, 2018
Study Type : Animal Study
Additional Links
Diseases : Brain Inflammation , Burns: Severe
Therapeutic Actions : Hyperbaric Treatment
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effect of electroacupuncture at Wnt/β-catenin signaling pathway on inhibiting cartilage degeneration in rats with knee osteoarthritis.Oct 11, 2019

Pubmed Data : Zhongguo Zhen Jiu. 2019 Oct 12 ;39(10):1081-6. PMID: 31621261
Article Published Date : Oct 11, 2019
Study Type : Animal Study
Additional Links
Diseases : Osteoarthritis: Knee
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Wnt/β-catenin signaling pathway modulation
[+]

Effect of hydrogen-rich water on the chondriosome damage and cytokines in brain tissue of rats with traumatic brain injury.Mar 31, 2018

Pubmed Data : Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Apr ;30(4):317-321. PMID: 29663991
Article Published Date : Mar 31, 2018
Study Type : Animal Study
Additional Links
Substances : Hydrogen Water
Diseases : Brain Injury: Traumatic
Pharmacological Actions : Interleukin-1 beta downregulation, Neuroprotective Agents, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of electroacupuncture on inflammatory response of cardiac muscle tissue.May 11, 2018

Pubmed Data : Zhongguo Zhen Jiu. 2018 May 12 ;38(5):5133-8. PMID: 29797917
Article Published Date : May 11, 2018
Study Type : Animal Study
Additional Links
Diseases : Myocardial Ischemia
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Cardioprotective, Interleukin-1 beta downregulation, Interleukin-8 downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet.Dec 19, 2017

Pubmed Data : Zhonghua Gan Zang Bing Za Zhi. 2017 Dec 20 ;25(12):927-933. PMID: 29325294
Article Published Date : Dec 19, 2017
Study Type : Animal Study
Additional Links
Substances : FOS (Fructooligosaccharides), Lactobacillus paracasei
Diseases : High Fat Diet, Nonalcoholic fatty liver disease (NAFLD)
Pharmacological Actions : Anti-Inflammatory Agents, Hepatoprotective, Interleukin-1 beta downregulation, Interleukin-6 Downregulation, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice.May 31, 2012

Pubmed Data : J Leukoc Biol. 2012 Jun ;91(6):911-20. Epub 2012 Apr 2. PMID: 22469754
Article Published Date : May 31, 2012
Study Type : Animal Study
Additional Links
Substances : Palmitoylethanolamide
Diseases : Intestinal Ischemia
Pharmacological Actions : Interleukin-1 beta downregulation, NF-kappaB Inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]

EGCG attenuated abdominal aortic aneurysm progression in a rat model by preserving the aortic thickness and elastin content of the medial layer.May 31, 2017

Pubmed Data : J Vasc Surg. 2017 Jun ;65(6):1803-1812.e2. Epub 2016 Jul 26. PMID: 27473778
Article Published Date : May 31, 2017
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate)
Diseases : Aneurysm: Aortic
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Matrix metalloproteinase-2 (MMP-2) inhibitor, Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Electroacupuncture potentiates peripheral CB2 receptor-inhibited chronic pain in a mouse model of knee osteoarthritis.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Pain Res. 2018 ;11:2797-2808. Epub 2018 Nov 8. PMID: 30510442
Article Published Date : Dec 31, 2017
Study Type : Animal Study
Additional Links
Diseases : Chronic Pain, Osteoarthritis: Knee
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Electroacupuncture pretreatment attenuates inflammatory lung injury after cardiopulmonary bypass.Jan 23, 2019

Pubmed Data : Inflammation. 2019 Jan 24. Epub 2019 Jan 24. PMID: 30680695
Article Published Date : Jan 23, 2019
Study Type : Animal Study
Additional Links
Diseases : Cardiac Surgery
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation
[+]

Electroacupuncture reduced periodontal tissue breakdown and the expression of some proinflammatory mediators.May 31, 2015

Pubmed Data : J Periodontol. 2015 Jun ;86(6):801-11. Epub 2015 Mar 5. PMID: 25741581
Article Published Date : May 31, 2015
Study Type : Animal Study
Additional Links
Diseases : Periodontitis
Therapeutic Actions : Electroacupuncture
Pharmacological Actions : Anti-Inflammatory Agents, Interleukin-1 beta downregulation, Matrix metalloproteinase-8 (MMP-8) inhibitor
[+]

Electromagnetic radiation induces structural changes in the brains of rats and impacts redox and inflammatory systems.Jan 01, 2013