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Liver Damage
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321 Substances Researched for Liver Damage
Name
AC
CK
Focus
Curcumin
59
121
Silymarin
9
26
Ginsenosides
14
25
Milk Thistle
3
24
Nigella sativa (aka Black Seed)
12
22
Polyphenols
12
22
Puerarin
11
21
Thymoquinone
11
20
Resveratrol
8
18
Vitamin C
10
18
Anthocyanins
8
16
Flavonoids
9
16
Melatonin
5
16
Silibinin
4
15
Turmeric
7
14
Dandelion
6
12
Ginger
6
12
Turmeric: Fermented
2
12
Phyllanthus urinaria
2
11
Rose
6
11
Black Tea
5
10
Fermented Foods and Beverages
5
10
Grape Seed Extract
5
10
Sesamol
3
10
Naringenin
5
9
Olive leaf extract
5
9
Sulforaphane
6
9
Alpha-Lipoic Acid
4
8
Asiatic Acid
4
8
Bael
4
8
Beet
4
8
Blueberry
4
8
Camel Milk
4
8
Diallyl sulfide
4
8
Ellagic Acid
4
8
Garlic
4
8
Geraniol
4
8
Honey
4
8
Lycopene
4
8
Mangiferin
3
8
Radish
5
8
Reishi Mushroom
4
8
Sweet Potato: Purple
4
8
Vitamin D
4
8
Astaxanthin
4
7
Fucoidan
4
7
Carrot
3
6
Carvacrol
3
6
Catechin
3
6
Chlorella (Algae)
2
6
Date Seeds
2
6
Dates
3
6
Diosmin
3
6
Fenugreek
3
6
Genistein
3
6
Gingerol
3
6
Ginkgo biloba
2
6
Green Tea
3
6
Jujube
3
6
Lactobacillus plantarum
3
6
Olive Oil
3
6
Pomegranate
3
6
Quercetin
3
6
Royal Jelly
2
6
Sea buckthorn
3
6
Shikonin
3
6
Solanum nigrum (black nightshade)
3
6
Vitamin E
3
6
Yellow Tea
3
6
Zataria multiflora
3
6
Artichoke
3
5
Citrus naringin
3
5
EGCG (Epigallocatechin gallate)
3
5
Fig
3
5
Genipin
3
5
Indole-3-Carbinol
3
5
NAC (N-acetyl-L-cysteine)
3
5
Rosemary
3
5
Apple Polyphenols
2
4
Apricot
2
4
Artesunate
1
4
Ayurvedic formulation: Liv52
2
4
Beeswax
2
4
Berberine
2
4
Berries: All
2
4
Blue Honeysuckle
2
4
Caffeic acid phenethyl ester
2
4
Chlorogenic Acid
2
4
Choline
2
4
Citrus Peel
2
4
Cranberry
2
4
Crocin
2
4
DHA (Docosahexaenoic Acid)
2
4
Dill
2
4
EPA (Eicosapentaenoic Acid)
2
4
Embelia ribes
2
4
Garlic: Aged
2
4
Henna
2
4
Hesperidin
2
4
Hibiscus sabdariffa
2
4
Hu Zhang (Polygonum cuspidatum)
1
4
Hydrogen Water
2
4
Hydroxytyrosol
2
4
Isoliquiritigenin
2
4
Juniper
2
4
Kombucha Tea
3
4
Lactobacillus casei
2
4
Litchi
2
4
Lotus
3
4
Luteolin
2
4
Lychee
2
4
Myricetin
2
4
Noni
2
4
Onion
2
4
Papaya
2
4
Passion Flower
2
4
Phloretin
3
4
Piceatannol
2
4
Pomegranate Peel
2
4
Pomegranate Seed
2
4
Potato
2
4
Propolis: Bee
2
4
Rooibos
2
4
Saffron
2
4
Selenium
2
4
Shiitake Mushroom
2
4
Stevia
2
4
Verbascoside
2
4
White Tea
2
4
Xanthohumol
2
4
Yeast
2
4
Zinc
2
4
Amygdalin (laetrile)
2
3
Chaga Mushroom (Inonotus obliquus)
2
3
D-Limonene
2
3
Lactobacillus fermentum
2
3
Lignans
2
3
Mulberry
2
3
Oleanolic acid
2
3
Thistle
2
3
Ursolic Acid
2
3
Ajwain
1
2
Almond
1
2
Andrographis
1
2
Anise
1
2
Antrodia camphorata
1
2
Apigenin
1
2
Apocynin
1
2
Apples
1
2
Apricot Kernel
1
2
Arginine
1
2
Ashwagandha
1
2
Baccharis trimera
1
2
Bacopa
1
2
Bamboo
1
2
Banana Peel
1
2
Banana Stem
1
2
Barberry
1
2
Barley
1
2
Beta-Caryophyllene
1
2
Bilberry
1
2
Bile salts
1
2
Bitter Apple
1
2
Bitter Melon
1
2
Black Currant
1
2
Black Raspberry
1
2
Black Tea Theaflavins
1
2
Broccoli Sprouts
1
2
Bromelain
1
2
Burdock
1
2
Butterbur
1
2
Cabbage
1
2
Caffeine
1
2
Cannabidiol
1
2
Capsaicin
1
2
Carotenoids
1
2
Celery
1
2
Celosia cristata (cockscomb)
1
2
Centella asiatica
1
2
Chamomile
1
2
Chickpea
1
2
Chicory
1
2
Chrysanthemum Indicum
1
2
Chrysin
1
2
Cinnamon
1
2
Cissus quadrangularis
1
2
Coconut Oil
1
2
Coconut Water
1
2
Coenzyme Q10
1
2
Coffee: Green/Unroasted
1
2
Cordyceps sinensis
1
2
Coriandrum sativum
1
2
Cucurbitacin B
1
2
Cumin
1
2
Cysteine (see N-Acetylcysteine)
1
2
Dibenzoylmethane (DBM)
1
2
Earthworms
1
2
Echinacea
1
2
Eggplant
1
2
Elderberry
1
2
Emodin
1
2
Eriodictyol
1
2
Feverfew
1
2
Fisetin
1
2
Fish Oil
1
2
Flaxseed
1
2
Folic Acid
1
2
Gallic Acid
1
2
Garden Cress (Lepidium sativum)
1
2
Geranium
1
2
Ginseng
1
2
Glycyrrhizin
1
2
Goat Milk
1
2
Goji
1
2
Gold (nanoparticles)
1
2
Goldenseal
1
2
Gotu Kola
1
2
Grape
1
2
Guava
1
2
Guduchi
1
2
Hibiscus rosa-sinensis
1
2
Hops
1
2
Horehound
1
2
Kimchi
1
2
Lactobacillus probiotics
1
2
Lactobacillus reuteri
1
2
Lactobacillus rhamnosus GG
1
2
Lactobacillus salivarius
1
2
Ligustrazine
1
2
Long Pepper
1
2
Loquat Seeds
1
2
Lutein
1
2
Magnesium
1
2
Mango
1
2
Medicinal Mushrooms
1
2
Mint
1
2
Miso
1
2
Modified Arabinoxylan Rice Bran (MGN-3)
1
2
Mucuna pruriens (aka Velvet Beans)
1
2
Myrica rubra
1
2
Nettle
1
2
Nicotinamide adenine dinucleotide (NADH)
1
2
Nobiletin
1
2
Nutmeg
1
2
Oak
1
2
Okra
1
2
Oleuropein
1
2
Olive
1
2
Orange
1
2
Oregano
1
2
Oyster Mushroom
1
2
Paeoniflorin
1
2
Palash
1
2
Palmitoylethanolamide
1
2
Panax Notoginseng
1
2
Peppermint
1
2
Phosphatidylcholine
1
2
Pine Bark Extract
1
2
Piper cubeba (Cubeb)
1
2
Piperine
1
2
Plant Stem Cells
1
2
Proanthocyanidins
1
2
Probiotics
1
2
Prunella vulgaris
1
2
Pterocarpus marsupium
1
2
Pterostilbene
1
2
Pumpkin Seed Oil/Meal
1
2
Purslane
1
2
Raspberry
1
2
Red Cabbage
1
2
Rice Bran
1
2
Rice: Brown
1
2
Rice: Parboiled
1
2
Rosemaric Acid
1
2
Sage
1
2
Saikosaponin
1
2
Salvia miltiorrhiza
1
2
Semecarpus anacardium
1
2
Sesame Seed Oil
1
2
Sessile Joyweed
1
2
Silica Hydride
1
2
Soy
1
2
Spirulina
1
2
Stilbenes
1
2
Strawberry
1
2
Tannic Acid
1
2
Taro
1
2
Taurine
1
2
Thymol
1
2
Tyrosine
1
2
Urine
1
2
Urine: Cow
1
2
Vanillin
1
2
Vitexins
1
2
Walnut
1
2
Water: Deuterium Depleted
1
2
Water: Electrolyzed Reduced
1
2
Yoghurt
1
2
Agrimony
1
1
Allicin
1
1
Astragaloside
1
1
Blackberry
1
1
Caraway
1
1
Coffee
1
1
Coriandor
1
1
Curcuminoids
1
1
Cyperus longus
1
1
Gynostemma
1
1
Haritaki (Terminalia chebula)
1
1
Honokiol
1
1
Kudzu
1
1
Lavender
1
1
Licorice
1
1
Lupeol
1
1
Prickly Pear Cactus
1
1
Rice: Black
1
1
Tanshinone IIA
1
1
Tetrahydrocurcumin
1
1
Vitex negundo
1
1
Wheat Grass
1
1
White Mulberry
1
1
92 Problem Substances Researched for Liver Damage
Name
AC
CK
Focus
Statin Drugs
22
124
Paracetamol
51
95
Acetaminophen
49
91
Simvastatin
9
77
Atorvastatin
12
69
Isoniazid
4
62
Pravastatin
5
45
Bisphenol A
14
41
Fluvastatin
3
40
Lovastatin
7
36
Aflatoxin
10
27
High Fructose Corn Syrup
5
18
Rosuvastatin
4
17
Concanavalin A
7
16
Cadmium
9
15
Tylenol
2
14
Perfluorooctanoic acid (PFOA)
2
12
Tamoxifen
3
12
Fluoroquinolone Antibiotic
1
10
Proton-Pump Inhibitors
1
10
Fluoxetine (trade name Prozac)
4
9
Mercury
3
9
Pesticides
5
9
Morphine
4
8
Tertiary butyl hydroperoxide
6
7
2-chlorobenzylidene malononitrile (CS)
1
6
Arsenic
4
6
Aspartame
3
6
Glyphosate
4
6
Quizalofop-P-ethyl
1
6
Bisphenol S
3
5
Aluminum
2
4
Arsenite
2
4
Benzo(a)pyrene
2
4
Butylated Hydroxytoluene (BHT)
2
4
Cisplatin
2
4
Dichlorvos
2
4
Electronic Cigarettes
2
4
Formaldehyde
2
4
Fructose
2
4
Lead
2
4
Monosodium Glutamate (MSG)
2
4
N-nitrosodiethylamine
2
4
Nanoparticles
2
4
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
2
4
Organophosphate Pesticides
2
4
Perfluorooctane sulfonate (PFOS)
2
4
Rosiglitazone (trade name Avandia)
2
4
Sodium Fluoride
2
4
Acrylamide
2
3
Cerivastatin
1
3
Cholesterol Lowering Drugs
1
3
Fenofibrates
1
3
Fluconazole
1
3
Zinc Oxide
2
3
Aluminum Hydroxide
1
2
Antibiotics
1
2
Arsenic Trioxide
1
2
Brilliant Blue FCF
1
2
Chlorpyrifos
1
2
Cypermethrin
1
2
Dexamethasone
1
2
Diclofenac
1
2
Erythrosine
1
2
Ethylene Glycol
1
2
FD&C Red #40
1
2
Food Colorings
1
2
Insulin
1
2
Metanil-Yellow Dye
1
2
N-nitrosodimethylamine
1
2
Organophosphates
1
2
Paclitaxel
1
2
Ponceau 4R (New Coccine)
1
2
Selective Serotonin Reuptake Inhibitors (SSRIs)
1
2
Sucralose (aka Splenda)
1
2
Sucrose
1
2
Sugar Sweetened Beverages
1
2
Tartrazine (Yellow Food Dye)
1
2
Thiazolidinediones
1
2
Titanium Dioxide
1
2
Titanium Nanoparticles
1
2
Toluene
1
2
Trans Fatty Acids
1
2
Vaccine Adjuvants
1
2
Zoledronic Acid
1
2
Amiodarone
1
1
Dimethoate
1
1
Irinotecan
1
1
Methotrexate
1
1
Parabens
1
1
Triclosan
1
1
Zineb
1
1
6 Problematic Actions Researched for Liver Damage
Name
AC
CK
Focus
Western Diet
2
4
Electromagnetic Fields
1
2
Mobile Phone Radiation
1
2
Vaccination: All
1
2
Vaccination: Hepatitis B
1
2
Nanotechnology
1
1
Research Articles
708
Cumulative Knowledge Score
1145
Overall Research Rating
EXCELLENT
Related Topics
The Following are Sub-Topics of Liver Damage
Liver Damage: Drug-Induced
Liver Damage: Aflatoxin-Induced
Chemically-Induced Liver Damage
Chemotherapy-Induced Liver Toxicity
View the Evidence:
834 Abstracts with Liver Damage Research
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[+]
Prophylactic therapy of milk thistle on anti-tuberculosis drug-induced liver injury.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Can J Gastroenterol Hepatol. 2019 ;2019:3192351. Epub 2019 Jan 10. PMID:
30733935
Article Published Date
: Dec 31, 2018
Study Type
: Meta Analysis
Additional Links
Substances
:
Milk Thistle
Diseases
:
Chemically-Induced Liver Damage
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
The use of statins for LDL suppression is associated with increased risk for cancer.
Jul 31, 2007
Click here to read the entire abstract
Pubmed Data
: J Am Coll Cardiol. 2007 Jul 31 ;50(5):409-18. Epub 2007 Jul 16. PMID:
17662392
Article Published Date
: Jul 31, 2007
Study Type
: Meta Analysis
Additional Links
Diseases
:
Cancers: All
,
Chemically-Induced Liver Damage
,
High Cholesterol
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
,
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Atorvastatin-induced acute pancreatitis has been reported.
Jan 01, 2011
Click here to read the entire abstract
Pubmed Data
: J Pharmacol Pharmacother. 2011 Jan ;2(1):40-2. PMID:
21701646
Article Published Date
: Jan 01, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Pancreatitis
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Autoimmune hepatitis associated with atorvastatin use has been reported.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2003 Aug ;15(8):921-4. PMID:
12867804
Article Published Date
: Aug 01, 2003
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol A was detected above the detection limit in all samples in individuals affected by non-alcoholic fatty liver disease.
Jun 04, 2017
Click here to read the entire abstract
Pubmed Data
: J Pharm Biomed Anal. 2017 Jun 5 ;140:105-112. Epub 2017 Mar 10. PMID:
28346880
Article Published Date
: Jun 04, 2017
Study Type
: Human In Vitro, Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Additional Keywords
:
Bisphenol A
,
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Combined treatment including melatonin resulted in the improvement of general conditions in 81.7% of the patients
Dec 31, 2012
Click here to read the entire abstract
Pubmed Data
: Klin Med (Mosk). 2013 ;91(3):50-3. PMID:
23789453
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Melatonin
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Plant Extracts
[+]
Drug-induced liver toxicity (particularly acetaminophen-induced liver toxicity) has replaced viral hepatitis as the most single frequent cause of acute liver failutre in ubran
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: Z Gastroenterol. 2009 Sep;47(9):807-13. Epub 2009 Sep 11. PMID:
19750427
Article Published Date
: Sep 01, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Tylenol
[+]
Exposure of children to even low doses of BPA may adversely affect later liver function.
Nov 16, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Res. 2017 Nov 17 ;161:195-201. Epub 2017 Nov 17. PMID:
29156342
Article Published Date
: Nov 16, 2017
Study Type
: Human Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
[+]
Fermented turmeric powder is well-tolerated and effective in subjects with elevated alanine transaminase levels.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2013 ;13:58. Epub 2013 Mar 8. PMID:
23497020
Article Published Date
: Dec 31, 2012
Study Type
: Human Study
Additional Links
Substances
:
Turmeric: Fermented
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
Fluoroquinolone therapy and idiosyncratic acute liver injury: a population-based study.
Aug 12, 2012
Click here to read the entire abstract
Pubmed Data
: CMAJ. 2012 Aug 13. Epub 2012 Aug 13. PMID:
22891208
Article Published Date
: Aug 12, 2012
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Fluoroquinolone Antibiotic
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fluvastatin has been linked to adverse hepatic reactions.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Drug Saf. 2006 ;29(12):1163-72. PMID:
17147462
Article Published Date
: Jan 01, 2006
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Nutrient Depletion: Statin Drugs
Problem Substances
:
Fluvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Fructose-associated hepatotoxicity indexed by the lactate dehydrogenase isoenzyme LDH-5.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Med Hypotheses. 2019 Mar ;124:40-41. Epub 2019 Feb 4. PMID:
30798914
Article Published Date
: Feb 28, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Nonalcoholic fatty liver disease (NAFLD)
Problem Substances
:
High Fructose Corn Syrup
[+]
Isoniazid has been associated with grade 3 or 4 liver failure in 1.4%-5.2% of patients being treated for latent tuberculosis infection.
Dec 15, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Infect Dis. 2009 Dec 15;49(12):1883-9. PMID:
19911936
Article Published Date
: Dec 15, 2009
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Problem Substances
:
Isoniazid
[+]
Isoniazid treatment in latent tuberculosis infection may be associated with moderate-to-severe liver damage without symptoms.
Jul 01, 2005
Click here to read the entire abstract
Pubmed Data
: Chest. 2005 Jul;128(1):116-23. PMID:
16002924
Article Published Date
: Jul 01, 2005
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Liver failure and damage are rare but severe unintended consequences of statin drug use.
Aug 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Hepatol. 2011 Aug 31. Epub 2011 Aug 31. PMID:
21889469
Article Published Date
: Aug 31, 2011
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
,
Liver Disease
,
Liver Failure: Drug Induced
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
More than half of patients who present at the hospital with acetaminophen-induced liver damage or liver failure have undetectable levels of acetaminophen.
Feb 04, 2019
Click here to read the entire abstract
Pubmed Data
: Clin Gastroenterol Hepatol. 2019 Feb 5. Epub 2019 Feb 5. PMID:
30731196
Article Published Date
: Feb 04, 2019
Study Type
: Human Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
Perfluorooctanoic acid has hepatotoxic effects.
Jul 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Environ Health Perspect. 2016 Aug ;124(8):1227-33. Epub 2016 Mar 15. PMID:
26978841
Article Published Date
: Jul 31, 2016
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Perfluorinated Compound Toxicity
Problem Substances
:
Perfluorooctanoic acid (PFOA)
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Phyllanthus Urinaria is useful in preventing or delaying the development of HBV-associated cirrhosis to hepatocellular carcinoma.
Mar 24, 2013
Click here to read the entire abstract
Pubmed Data
: Chin J Integr Med. 2013 Mar 25. Epub 2013 Mar 25. PMID:
23529834
Article Published Date
: Mar 24, 2013
Study Type
: Human Study
Additional Links
Substances
:
Phyllanthus urinaria
Diseases
:
Liver Cancer: Hepatitis B Associated
,
Liver Cancer: Prevention
,
Liver Cirrhosis
,
Liver Damage
Pharmacological Actions
:
Chemopreventive
Additional Keywords
:
Significant Treatment Outcome
[+]
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Clin Oncol. 2017 Nov ;7(5):891-896. Epub 2017 Sep 1. PMID:
29142752
Article Published Date
: Oct 31, 2017
Study Type
: Human Study
Additional Links
Substances
:
Hydrogen Water
Diseases
:
Colorectal Cancer
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Severe liver toxicity requiring discontinuation occurs in 5% of simvastatin-treated patients and 4.5% of pravastatin-treated patients.
Jan 01, 1992
Click here to read the entire abstract
Pubmed Data
: Minerva Gastroenterol Dietol. 1992 Jan-Mar;38(1):41-4. PMID:
1520752
Article Published Date
: Jan 01, 1992
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Pravastatin
,
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Severe, even fatal liver injuries have resulted as a consequence of isoniazid treatment in individuals with latent tuberculosis.
Mar 05, 2010
Click here to read the entire abstract
Pubmed Data
: MMWR Morb Mortal Wkly Rep. 2010 Mar 5;59(8):224-9. PMID:
20203555
Article Published Date
: Mar 05, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage: Drug-Induced
,
Tuberculosis
Additional Keywords
:
Iatrogenic Disease
Problem Substances
:
Isoniazid
[+]
Silibinin could be beneficial in preventing drug-induced liver injury in tuberculosis treatments.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Clin Exp Med. 2015 ;8(3):4320-7. Epub 2015 Mar 15. PMID:
26064348
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silibinin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Silymarin has an efficacy to prevent liver injury from standard combined antituberculosis drugs without significant adverse effects.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2015 ;15(1):334. Epub 2015 Sep 23. PMID:
26400476
Article Published Date
: Dec 31, 2014
Study Type
: Human Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage: Drug-Induced
,
Tuberculosis
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Tamoxifen treatment for breast cancer may result in fatty liver.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Oncol Rep. 2000 Nov-Dec;7(6):1299-304. PMID:
11032933
Article Published Date
: Nov 01, 2000
Study Type
: Human Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Additional Keywords
:
Drug: 5-flourouracil
,
Drug: Doxorubicin
,
Drug: Tamoxifen
Problem Substances
:
Tamoxifen
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
There is evidence that aflatoxin exposure plays a role in the pathogenesis of liver cancer in the US population.
Jan 01, 1999
Click here to read the entire abstract
Pubmed Data
: Nutr Cancer. 1999 ;35(1):27-33. PMID:
10624703
Article Published Date
: Jan 01, 1999
Study Type
: Human Study
Additional Links
Diseases
:
Aflatoxicosis
,
Liver Cancer
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Tumor Suppressor Protein p53 Upregulation
Problem Substances
:
Aflatoxin
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Treatment with proton pump inhibitors is associated with increased mortality in patients with pyogenic liver abscess.
Feb 28, 2018
Click here to read the entire abstract
Pubmed Data
: Aliment Pharmacol Ther. 2018 Mar ;47(6):801-808. Epub 2018 Jan 12. PMID:
29327781
Article Published Date
: Feb 28, 2018
Study Type
: Human Study
Additional Links
Diseases
:
Liver Damage
Additional Keywords
:
Risk Factors
Problem Substances
:
Proton-Pump Inhibitors
[+]
Unintended consequences of statin drug use are increased risk of esophageal cancer, kidney failure, cataract, liver dysfunction and myopathies.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: BMJ. 2010;340:c2197. Epub 2010 May 20. PMID:
20488911
Article Published Date
: Jan 01, 2010
Study Type
: Human Study
Additional Links
Diseases
:
Cardiovascular Diseases
,
Cataract
,
Chemically-Induced Liver Damage
,
Esophageal Cancer
,
Kidney Failure
,
Myopathies
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Fluvastatin
,
Pravastatin
,
Rosuvastatin
,
Simvastatin
,
Statin Drugs
[+]
Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue.
Aug 11, 2019
Click here to read the entire abstract
Pubmed Data
: Basic Clin Pharmacol Toxicol. 2019 Aug 12. Epub 2019 Aug 12. PMID:
31403256
Article Published Date
: Aug 11, 2019
Study Type
: Animal Study, Human In Vitro
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
[+]
Curcumin could modulate hepatocyte epithelial-mesenchymal transition implicated in treatment of liver fibrosis.
Aug 23, 2015
Click here to read the entire abstract
Pubmed Data
: Lab Invest. 2015 Aug 24. Epub 2015 Aug 24. PMID:
26302188
Article Published Date
: Aug 23, 2015
Study Type
: Human In Vitro
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Mangiferin could ameliorate methylmercury mediated mitochondrial dysfunction in human hepatic cells in vitro.
Jan 31, 2017
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol. 2017 Feb ;32(2):630-644. Epub 2016 Mar 28. PMID:
28071871
Article Published Date
: Jan 31, 2017
Study Type
: Human In Vitro
Additional Links
Substances
:
Mangiferin
Diseases
:
Chemically-Induced Liver Damage
,
Mercury Poisoning
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Methylmercury
Problem Substances
:
Mercury
[+]
A case of hepatitis caused by simvastatin has been reported.
Jan 01, 1991
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Clin Biol. 1991 ;15(1):94-5. PMID:
2010080
Article Published Date
: Jan 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Simvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
A case report of fluoxetine-induced Stevens-Johnson syndrome and liver injury.
Jan 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Clin Pharm Ther. 2019 Feb ;44(1):115-118. Epub 2018 Oct 8. PMID:
30296343
Article Published Date
: Jan 31, 2019
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Stevens-Johnson Syndrome
Problem Substances
:
Fluoxetine (trade name Prozac)
[+]
Acute cholestatic hepatitis associated with atorvastatin use has been reported.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 2006 Jan ;29(1):21-4. PMID:
16393626
Article Published Date
: Jan 01, 2006
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis associated with pravastatin has been reported.
May 01, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Gastroenterol. 1999 May ;94(5):1388-90. PMID:
10235223
Article Published Date
: May 01, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Pravastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by cerivastatin has been reported.
May 18, 2002
Click here to read the entire abstract
Pubmed Data
: Med Clin (Barc). 2002 May 18 ;118(18):717. PMID:
12042141
Article Published Date
: May 18, 2002
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Cerivastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute cholestatic hepatitis induced by fenofibrate has been reported.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Clin Pharm Ther. 2009 Oct;34(5):599-602. PMID:
19744016
Article Published Date
: Oct 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Hepatitis
Problem Substances
:
Fenofibrates
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Acute exposure to CS tear gas has been reported to cause several health problems in an individual.
Dec 26, 1981
Click here to read the entire abstract
Pubmed Data
: Schweiz Med Wochenschr. 1981 Dec 26 ;111(52):2056-60. PMID:
6800031
Article Published Date
: Dec 26, 1981
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Heart Failure
,
Liver Damage
,
Pneumonia
Problem Substances
:
2-chlorobenzylidene malononitrile (CS)
[+]
Acute hepatitis induced by lovastatin has been reported.
Sep 01, 1994
Click here to read the entire abstract
Pubmed Data
: Dig Dis Sci. 1994 Sep ;39(9):2032-3. PMID:
8082513
Article Published Date
: Sep 01, 1994
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
After taking 30 mg artichoke leaf extract tea 3 times a day, patients bilirubin levels significantly declined at the end of the first week and all liver function tests were normalized within 2 months.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Case Reports Hepatol. 2014 ;2014:697359. Epub 2014 Sep 3. PMID:
25374729
Article Published Date
: Dec 31, 2013
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Significant Treatment Outcome
Problem Substances
:
Fluconazole
[+]
Atorvastatin has been reported to have caused severe acute hepatitis with symptomatic cholestasis for more than 3 months and bile duct injury.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Acta Gastroenterol Belg. 2008 Jul-Sep;71(3):318-20. PMID:
19198578
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Bile Duct Injury
,
Chemically-Induced Liver Damage
,
Cholestasis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Atorvastatin-induced cholestatic hepatitis in a young woman with systemic lupus erythematosus has been reported.
Aug 09, 1999
Click here to read the entire abstract
Pubmed Data
: Arch Intern Med. 1999 Aug 9-23;159(15):1811-2. PMID:
10448788
Article Published Date
: Aug 09, 1999
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Cholestatic jaundice during lovastatin medication has been reported.
May 10, 1991
Click here to read the entire abstract
Pubmed Data
: Dtsch Med Wochenschr. 1991 May 10 ;116(19):739-40. PMID:
2026107
Article Published Date
: May 10, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Cholestasis
,
Jaundice
,
Liver Damage: Drug-Induced
,
Statin-Induced Pathologies
Problem Substances
:
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Cholestatic jaundice induced by atorvastatin has been observed.
Jul 01, 2009
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Isr Med Assoc J. 2009 Jul ;11(7):440-1. PMID:
19911499
Article Published Date
: Jul 01, 2009
Study Type
: Human: Case Report
Additional Links
Diseases
:
Autoimmune Diseases
,
Chemically-Induced Liver Damage
,
Hepatitis: Cholestatic
,
Jaundice
Problem Substances
:
Atorvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Hepatitis associated with treatment with lovastatin has been reported.
Mar 01, 1998
Click here to read the entire abstract
Pubmed Data
: Gastroenterol Hepatol. 1998 Mar ;21(3):127-8. PMID:
9607293
Article Published Date
: Mar 01, 1998
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Liver fibrosis has been attributed to lipid lowering medications.
Sep 01, 2001
Click here to read the entire abstract
Pubmed Data
: J Intern Med. 2001 Sep ;250(3):249-54. PMID:
11555130
Article Published Date
: Sep 01, 2001
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Liver Cirrhosis
,
Liver Fibrosis
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Cholesterol Lowering Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Lovastatin monotherapy has been reported to have been a cause of rhabdomyolysis, acute renal failure and hepatopathy.
Jul 01, 1997
Click here to read the entire abstract
Pubmed Data
: Jpn Heart J. 1997 Jul ;38(4):541-5. PMID:
9350151
Article Published Date
: Jul 01, 1997
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Failure: Acute
,
Rhabdomyolysis
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Lovastatin
Adverse Pharmacological Actions
:
Nephrotoxic
[+]
Mixed cholestatic/hepatocellular liver injury induced by the herbicide quizalofop-p-ethyl has been reported.
Oct 01, 2007
Click here to read the entire abstract
Pubmed Data
: Environ Health Perspect. 2007 Oct ;115(10):1479-81. PMID:
17938739
Article Published Date
: Oct 01, 2007
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
Problem Substances
:
Quizalofop-P-ethyl
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Reversible acute hepatitis induced by rosuvastatin has been reported.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: South Med J. 2008 Jul ;101(7):768. PMID:
19209117
Article Published Date
: Jul 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Statin-Induced Pathologies
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Rosuvastatin-associated hepatitis with autoimmune features has been reported.
May 01, 2005
Click here to read the entire abstract
Pubmed Data
: Eur J Gastroenterol Hepatol. 2005 May ;17(5):589-90. PMID:
15827453
Article Published Date
: May 01, 2005
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Autoimmune
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Rosuvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause cholestatic hepatitis.
Apr 01, 1991
Click here to read the entire abstract
Pubmed Data
: Recenti Prog Med. 1991 Apr ;82(4):233-5. PMID:
1857844
Article Published Date
: Apr 01, 1991
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Cholestasis
,
Elevated: ALT
,
GGT
,
Hepatitis: Cholestatic
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Simvastatin has been reported to cause liver lesions.
Apr 13, 1996
Click here to read the entire abstract
Pubmed Data
: Ned Tijdschr Geneeskd. 1996 Apr 13 ;140(15):846-8. PMID:
8668280
Article Published Date
: Apr 13, 1996
Study Type
: Human: Case Report
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Jaundice
,
Liver Damage
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
[+]
Simvastatin-ezetimibe-induced hepatic failure necessitating liver transplantation has been reported.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Pharmacotherapy. 2008 Sep ;28(9):1188-93. PMID:
18752389
Article Published Date
: Sep 01, 2008
Study Type
: Human: Case Report
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Organ Transplantation: Liver
,
Statin-Induced Pathologies
Pharmacological Actions
:
Anticholesteremic Agents
Problem Substances
:
Simvastatin
,
Statin Drugs
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Co-administration of N-Acetylcysteine and Acetaminophen efficiently blocks Acetaminophen toxicity.
Jul 31, 2015
Click here to read the entire abstract
Pubmed Data
: Drug Dev Res. 2015 Aug ;76(5):251-8. Epub 2015 Aug 7. PMID:
26250417
Article Published Date
: Jul 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
NAC (N-acetyl-L-cysteine)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
F. religisoa protects against isoniazid, rifampicin and paracetamol induced oxidative liver injury in rats.
Sep 30, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacognosy Res. 2013 Oct ;5(4):271-6. PMID:
24174821
Article Published Date
: Sep 30, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Isoniazid
,
Paracetamol
[+]
"Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury."
Oct 01, 2012
Click here to read the entire abstract
Pubmed Data
: Toxicol Lett. 2012 Oct 2 ;214(1):9-18. Epub 2012 Aug 10. PMID:
22902350
Article Published Date
: Oct 01, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antineoplastic Agents
Additional Keywords
:
Chimera
[+]
"Vitamin E protects against oxidative damage caused by formaldehyde in the liver and plasma of rats."
Oct 01, 2006
Click here to read the entire abstract
Pubmed Data
: Mol Cell Biochem. 2006 Oct ;290(1-2):61-7. Epub 2006 Aug 26. PMID:
16937016
Article Published Date
: Oct 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin E
Diseases
:
Chemically-Induced Liver Damage
,
Formaldehyde Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Formaldehyde
[+]
6-gingerol, an active ingredient of ginger, protects acetaminophen-induced liver damage in mice.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Zhong Xi Yi Jie He Xue Bao. 2011 Nov ;9(11):1264-9. PMID:
22088594
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Gingerol
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
A curcumin-phospholipid complex works synergistically to protect the livers of rats following chemical exposure.
Feb 07, 2007
Click here to read the entire abstract
Pubmed Data
: Int J Pharm. 2007 Feb 7;330(1-2):155-63. Epub 2006 Sep 23. PMID:
17112692
Article Published Date
: Feb 07, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Phosphatidylcholine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A new possible mechanism by which punicalagin protects against liver injury induced by type 2 diabetes mellitus.
Nov 06, 2019
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2019 Nov 7. Epub 2019 Nov 7. PMID:
31698901
Article Published Date
: Nov 06, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Punicalagin
Diseases
:
Diabetes Mellitus: Type 2
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
A phenolics rich extract of ginger had protective effects against Aflatoxin B1-induced oxidative stress and hepatotoxicity.
May 01, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 May 2 ;91:415-424. Epub 2017 May 2. PMID:
28475920
Article Published Date
: May 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Ginger
,
Gingerol
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 inducer
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Aflatoxin
[+]
A water extract of the leaves of Z. jujuba is efficacious for prevention and treatment of carbon tetrachloride induced hepatic injury in mice.
Feb 21, 2017
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2017 Feb 22 ;8(2):816-822. PMID:
28124048
Article Published Date
: Feb 21, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Jujube
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
A. cerana honey can prevent bromobenzene-induced hepatic damage in mice.
Jan 15, 2018
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2018 Jan 16. Epub 2018 Jan 16. PMID:
29337369
Article Published Date
: Jan 15, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A. graveolens extract showed an ameliorative effect against liver oxidative stress in adjuvant-induced arthritis.
May 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Prev Nutr Food Sci. 2016 Jun ;21(2):79-84. Epub 2016 Jun 30. PMID:
27390722
Article Published Date
: May 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Celery
Diseases
:
Arthritis
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
A. lappa could protect the liver cells from carbon tetrachloride or acetaminophen-induced liver damages.
Dec 31, 1999
Click here to read the entire abstract
Pubmed Data
: Am J Chin Med. 2000 ;28(2):163-73. PMID:
10999435
Article Published Date
: Dec 31, 1999
Study Type
: Animal Study
Additional Links
Substances
:
Burdock
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
A. marmelos attenuates carbon tetrachloride-mediated hepatic oxidative stress, toxicity, tumor promotion.
Mar 31, 2009
Click here to read the entire abstract
Pubmed Data
: J Enzyme Inhib Med Chem. 2009 Apr ;24(2):320-7. PMID:
18830880
Article Published Date
: Mar 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Antioxidants
,
Antiproliferative
Additional Keywords
:
Plant Extracts
[+]
A. sessilis has hepatoprotective activity against carbon tetrachloride liver damage.
Mar 31, 2018
Click here to read the entire abstract
Pubmed Data
: Indian J Clin Biochem. 2018 Apr ;33(2):190-195. Epub 2017 May 18. PMID:
29651210
Article Published Date
: Mar 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Sessile Joyweed
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
Accumulation of polystyrene microplastics in juvenile Chinese mitten crab and oxidative stress effects in the liver.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Aquat Toxicol. 2018 Jul ;200:28-36. Epub 2018 Apr 24. PMID:
29709883
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Liver Damage
,
Oxidative Stress
Additional Keywords
:
Microplastic
[+]
Acetaminophen could cause transient mitochondrial dysfunction that may synergize with other stresses to promote liver damage and steatosis.
Dec 30, 2015
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2015 Dec 31. Epub 2015 Dec 31. PMID:
26721299
Article Published Date
: Dec 30, 2015
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Mitochondrial Dysfunction
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Acteoside has a protective and therapeutic effect on LPS-induced immunological liver injury in mice.
Oct 31, 2009
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2009 Nov ;75(14):1463-9. Epub 2009 Jun 22. PMID:
19548187
Article Published Date
: Oct 31, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Verbascoside
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2018 Jan ;54:125-130. Epub 2017 Nov 9. PMID:
29128856
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Chlorogenic Acid
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Acute treatment with Mangifera indica L. leaf extract attenuates liver inflammation in rats fed a cafeteria diet.
Jul 22, 2019
Click here to read the entire abstract
Pubmed Data
: Food Funct. 2019 Jul 23. Epub 2019 Jul 23. PMID:
31334539
Article Published Date
: Jul 22, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Mango leaf
Diseases
:
Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-10 upregulation
,
NF-kappaB Inhibitor
Anti Therapeutic Actions
:
Western Diet
[+]
Administration of silymarin significantly prevented acute liver injury induced by restraint stress.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2016 ;21(4). Epub 2016 Apr 1. PMID:
27043523
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Silymarin
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Administration of Zataria multiflora extract and carvacrol could reduce the oxidative damage in the rat liver induced by doxorubicin.
Nov 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed J. 2018 Dec ;41(6):340-347. Epub 2019 Jan 11. PMID:
30709575
Article Published Date
: Nov 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
,
Zataria multiflora
Diseases
:
Chemotherapy-Induced Toxicity: Doxorubicin
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Chemoprotective Agents
,
Hepatoprotective
[+]
Aegle marmelos methanol extract could protect against carbon tetrachloride.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Rep. 2018 ;5:1161-1168. Epub 2018 Oct 13. PMID:
30627516
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Bael
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Aged black garlic has hepatoprotective effects and suggests that supplementation might be a good adjuvant therapy for the management of liver injury.
Feb 28, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Toxicol Res. 2014 Mar ;30(1):49-54. PMID:
24795800
Article Published Date
: Feb 28, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Garlic: Aged
Diseases
:
Fatty Liver
,
High Fat Diet
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Ajwa date extract afforded significant protection against carbon tetrachloride-induced hepatocellular injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2017 Nov ;30(6):2183-2191. PMID:
29175788
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Dates
Diseases
:
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Ajwain attenuates chemically-induced liver damage in rats.
Feb 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Feb;47(2):279-82. Epub 2008 Oct 4. PMID:
18940228
Article Published Date
: Feb 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Ajwain
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Almond skin extract has hepatoprotective properties against chemically-induced liver cell damage.
Apr 29, 2010
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2010 Apr 29;185(2):101-9. Epub 2010 Mar 6. PMID:
20211157
Article Published Date
: Apr 29, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Almond
,
Catechin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Alpha lipoic acid possess protective effects against chlorpyrifos induced liver injury.
Feb 22, 2018
Click here to read the entire abstract
Pubmed Data
: Environ Toxicol Pharmacol. 2018 Feb 23 ;59:17-23. Epub 2018 Feb 23. PMID:
29500983
Article Published Date
: Feb 22, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Alpha-Lipoic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Chlorpyrifos
,
Pesticides
[+]
Ameliorative effects of Moringa oleifera leaf extract on levofloxacin-induced hepatic toxicity.
Feb 19, 2019
Click here to read the entire abstract
Pubmed Data
: Drug Chem Toxicol. 2019 Feb 20:1-7. Epub 2019 Feb 20. PMID:
30782023
Article Published Date
: Feb 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Antibiotic Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-10 upregulation
Problem Substances
:
Fluoroquinolone Antibiotic
,
Levofloxacin
[+]
Ameliorative impact of cold-pressed Rosmarinus officinalis oil against liver toxicity and genotoxic effects in streptozotocin-induced diabetes mellitus.
Jun 30, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Jul ;43(7):e12905. Epub 2019 May 20. PMID:
31353725
Article Published Date
: Jun 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Rosemary
Diseases
:
Diabetic Complications
,
Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hypolipidemic
[+]
Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis.
May 14, 2019
Click here to read the entire abstract
Pubmed Data
: Ann Anat. 2019 May 15 ;224:124-132. Epub 2019 May 15. PMID:
31100343
Article Published Date
: May 14, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Hepatitis: Autoimmune
,
Hepatitis: Lectin-Induced (concanavalin)
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Immunomodulatory
Problem Substances
:
Concanavalin A
[+]
Amygdalin reduces lipopolysaccharide-induced chronic liver injury.
Nov 30, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Artif Cells Nanomed Biotechnol. 2019 Dec ;47(1):2688-2697. PMID:
31257932
Article Published Date
: Nov 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Amygdalin (laetrile)
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
An anthocyanin-rich extract of Hibiscus sabdariffa calyces had hepatoprotective activity.
Aug 25, 2016
Click here to read the entire abstract
Pubmed Data
: Pharm Biol. 2016 Aug 26:1-10. Epub 2016 Aug 26. PMID:
27564372
Article Published Date
: Aug 25, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Hibiscus sabdariffa
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
An extract of P. guajava leaves and its isolated quercetin fraction have a hypolipidemic activity against carbon tetrachloride induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Pharmacogn Mag. 2018 Jan-Mar;14(53):4-8. Epub 2018 Feb 20. PMID:
29576694
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Guava
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Hypolipidemic
[+]
An extract of P. vulgaris alleviated carbon tetrachloride-induced hepatic in vivo.
Oct 12, 2015
Click here to read the entire abstract
Pubmed Data
: Planta Med. 2015 Oct 13. Epub 2015 Oct 13. PMID:
26460672
Article Published Date
: Oct 12, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Prunella vulgaris
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Interleukin-4 downregulation
,
Interleukin-8 downregulation
,
MicroRNA modulator
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
An extract of Stevia rebaudiana leaves and stevioside ameliorates lipopolysaccharide induced acute liver injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Nov ;95:1040-1050. Epub 2017 Sep 13. PMID:
28922721
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Stevia
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
An isoflavonoid from seeds of Lepidium sativum L. has a protective effect on hepatotoxicity induced by paracetamol.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2014 ;19(10):15440-51. Epub 2014 Sep 26. PMID:
25264831
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Garden Cress (Lepidium sativum)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
An unexpected role of cholesterol sulfotransferase and its regulation in sensitizing mice to acetaminophen induced liver injury.
Apr 02, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Pharmacol. 2019 Apr 3. Epub 2019 Apr 3. PMID:
30944208
Article Published Date
: Apr 02, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Andrographolide, a compound found within andrographis, has anti-tumor activity in chemically-induced liver damage.
Jun 01, 2005
Click here to read the entire abstract
Pubmed Data
: Nutrition. 2005 Jun;21(6):756-61. PMID:
19679627
Article Published Date
: Jun 01, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Andrographis
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury
Apr 30, 2018
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2018 May ;111:1133-1139. Epub 2018 Feb 19. PMID:
29415408
Article Published Date
: Apr 30, 2018
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Angelica sinensis pretreatment could effectively guard the liver and kidney of mice from D-galactose-induced injury.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2018 Sep ;21(9):887-898. Epub 2018 Aug 15. PMID:
30109956
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Angelica
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Kidney Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Renoprotective
[+]
Anise seed possesses protective effects against carbon tetrachloride (CCl4)-induced toxicity.
Jan 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Iran J Basic Med Sci. 2015 Feb ;18(2):205-11. PMID:
25825639
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Anise
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Essential Oils
[+]
Anthocyanin-rich black currant extract affords chemoprevention against chemically-induced liver cancer in rats.
Jan 07, 2011
Click here to read the entire abstract
Pubmed Data
: J Nutr Biochem. 2011 Jan 7. Epub 2011 Jan 7. PMID:
21216582
Article Published Date
: Jan 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Black Currant
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Bax/Bcl2 ratio: Increase
,
Chemopreventive
[+]
Anthocyanins from bilberry extract have strong antioxidant properties and therefore can be considered as powerful hepatoprotectives in natural products.
Jul 14, 2016
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2016 Jul 15 ;157:168-77. Epub 2016 Jun 14. PMID:
27312419
Article Published Date
: Jul 14, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Bilberry
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Anthocyanins isolated from blueberry ameliorates carbon tetrachloride induced liver fibrosis.
Sep 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Oct ;120:491-499. Epub 2018 Jul 27. PMID:
30056145
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Anti-hepatitic activity of ginsenoside Ro.
Nov 30, 1991
Click here to read the entire abstract
Pubmed Data
: Planta Med. 1991 Dec ;57(6):523-6. PMID:
1818342
Article Published Date
: Nov 30, 1991
Study Type
: Animal Study
Additional Links
Substances
:
Ginsenosides
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Antibiotics induced elevations of plasma bile acids in rats.
Jan 19, 2017
Click here to read the entire abstract
Pubmed Data
: Toxicol Sci. 2017 Jan 20. Epub 2017 Jan 20. PMID:
28108666
Article Published Date
: Jan 19, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Antibiotic Toxicity
,
Liver Damage: Drug-Induced
Problem Substances
:
Antibiotics
[+]
Antioxidant and hepatoprotective potential of Lawsonia inermis L. leaves against 2-acetylaminofluorene induced hepatic damage.
Jan 17, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2017 Jan 18 ;17(1):56. Epub 2017 Jan 18. PMID:
28100199
Article Published Date
: Jan 17, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Henna
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
antioxidant effect of thymoquinone could protect damage of liver parameters against morphine toxicity.
Dec 31, 2017
Click here to read the entire abstract
Pubmed Data
: Int J Prev Med. 2018 ;9:8. Epub 2018 Jan 29. PMID:
29441185
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Thymoquinone
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Morphine
[+]
Antioxidant traits and protective impact of Moringa oleifera leaf extract against diclofenac sodium-induced liver toxicity in rats.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: J Food Biochem. 2019 Feb ;43(2):e12704. Epub 2018 Oct 28. PMID:
31353658
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Moringa oleifera
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Apigenin significantly increases the enzyme antioxidant defence mechanisms in paracetamol-induced hepatotoxicity.
Mar 01, 2017
Click here to read the entire abstract
Pubmed Data
: Eur J Drug Metab Pharmacokinet. 2017 Mar 2. Epub 2017 Mar 2. PMID:
28255865
Article Published Date
: Mar 01, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apigenin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Apocynin prevented inflammation and oxidative stress in carbon tetra chloride induced hepatic dysfunction in rats.
Jul 31, 2017
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2017 Aug ;92:421-428. Epub 2017 May 27. PMID:
28558355
Article Published Date
: Jul 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Apocynin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Apple polyphenols exert protective effects against Con A-induced immunological liver injury.
Aug 23, 2016
Click here to read the entire abstract
Pubmed Data
: Chem Biol Interact. 2016 Aug 24. Epub 2016 Aug 24. PMID:
27567545
Article Published Date
: Aug 23, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Apple Polyphenols
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interferon Gamma Reducer
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Concanavalin A
[+]
Apricot (Prunus armeniaca L.) has a protective effect against fatty liver and damage induced by carbon tetrachloride in Wistar rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Br J Nutr. 2009 Dec;102(12):1767-75. PMID:
19822030
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Apricot supplementation and irradiation given in combination, offer maximum protection against DMBA-induced hepatic carcinogenesis.
Jul 31, 2014
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2014 Aug ;70:128-33. Epub 2014 May 10. PMID:
24819963
Article Published Date
: Jul 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Apricot
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy and Radiation Toxicity
,
Liver Cancer
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Anticarcinogenic Agents
,
NF-kappaB Inhibitor
[+]
Aqueous extracts of C. papaya may be useful in preventing carbon tetrachloride and acetaminophen induced liver toxicities.
Dec 31, 2015
Click here to read the entire abstract
Pubmed Data
: J Intercult Ethnopharmacol. 2016 Jan-Feb;5(1):27-35. Epub 2016 Jan 27. PMID:
27069723
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Papaya
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Aqueous extracts of leaves of R. sativus offer partial protection against hepatotoxicity induced by carbon tetrachloride.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Afr J Tradit Complement Altern Med. 2014 ;11(3):102-6. Epub 2014 Apr 3. PMID:
25371570
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Radish
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Aqueous extracts of Rosa damascene may prevent hepatic damage from acetaminophen induced toxicity in rats.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: J Environ Pathol Toxicol Oncol. 2012 ;31(3):193-201. PMID:
23339694
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Rose
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Artichoke extract ameliorates carbon tetrachloride-induced liver damage and oxidative stress in rats.
Sep 01, 2008
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2008 Sep;60(6):475-80. Epub 2008 Jun 25. PMID:
18583118
Article Published Date
: Sep 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
[+]
Artichoke leaf extract has liver protective effects and causes downregulation of oxidative stress in acute diazinon-induced liver injury.
Aug 29, 2019
Click here to read the entire abstract
Pubmed Data
: J Basic Clin Physiol Pharmacol. 2019 Aug 30 ;30(5). Epub 2019 Aug 30. PMID:
31469651
Article Published Date
: Aug 29, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Organophosphate Pesticides
[+]
Artichoke leaf extract may be used as a pharmaceutical phytomedicine in the treatment of liver diseases.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Springerplus. 2016 ;5:216. Epub 2016 Feb 29. PMID:
27026910
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Artichoke
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Catalase Up-Regulation
,
Hepatoprotective
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Artificial sweeteners cause cytoplasmic fatty change of varying degrees.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Coll Physicians Surg Pak. 2019 Sep ;29(9):848-851. PMID:
31455480
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Fatty Liver
Problem Substances
:
Aspartame
,
Sucralose (aka Splenda)
[+]
Association between serum CK-18 levels and the degree of liver damage in fructose-induced metabolic syndrome.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Metab Syndr Relat Disord. 2018 Sep ;16(7):350-357. Epub 2018 Jul 10. PMID:
29989845
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
High Fructose Diet
,
Liver Damage
,
Metabolic Diseases
[+]
Astaxanthin alleviated aflatoxin B1-induced liver damage.
Jul 02, 2019
Click here to read the entire abstract
Pubmed Data
: J Vet Med Sci. 2019 Jul 3. Epub 2019 Jul 3. PMID:
31270307
Article Published Date
: Jul 02, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Aflatoxicosis
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat.
Feb 01, 2010
Click here to read the entire abstract
Pubmed Data
: Mutat Res. 2010 Feb ;696(1):69-80. Epub 2009 Dec 28. PMID:
20038455
Article Published Date
: Feb 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
DNA damage
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Chemopreventive
,
Tumor Suppressor Protein p53 Upregulation
[+]
Astaxanthin provided protection for the liver against acetaminophen hepatotoxicity.
Jan 29, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Jan 30 ;45:26-33. Epub 2017 Jan 30. PMID:
28152447
Article Published Date
: Jan 29, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Astaxanthin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Atorvastatin may contribute to hepatopathy through suppressing oxidized and reduce coenzyme q10 and mitochondrial function in the liver.
Apr 20, 2012
Click here to read the entire abstract
Pubmed Data
: Physiol Res. 2012 Apr 20 ;61(2):185-93. Epub 2012 Jan 31. PMID:
22292717
Article Published Date
: Apr 20, 2012
Study Type
: Animal Study
Additional Links
Diseases
:
Liver Damage: Drug-Induced
,
Statin-Induced Pathologies
Problem Substances
:
Atorvastatin
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Augmentation of hepatoprotective potential of Aegle marmelos in combination with piperine.
Aug 19, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Chem Cent J. 2018 Aug 20 ;12(1):94. Epub 2018 Aug 20. PMID:
30123925
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Bael
,
Piperine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
B. trimera a potential candidate drug capable of protecting the liver against damage caused by Acetaminophen overdose.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mediators Inflamm. 2014 ;2014:196598. Epub 2014 Nov 12. PMID:
25435714
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Baccharis trimera
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Bacopa monnieri may provide a beneficial herbal remedy for the efficient management of opioid related hepatotoxicity and nephrotoxicity.
Jan 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Heliyon. 2016 Feb ;2(2):e00068. Epub 2016 Feb 15. PMID:
27441247
Article Published Date
: Jan 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Bacopa
Diseases
:
Kidney Damage: Drug-Induced
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Morphine
[+]
Banana peel polyphenols exert a good preventive effect against hepatic injury.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Exp Ther Med. 2016 May ;11(5):1947-1954. Epub 2016 Mar 11. PMID:
27168833
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Banana Peel
,
Polyphenols
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Barley sprouts have a protective effect against alcohol-induced liver injury.
Jul 20, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Nutrients. 2016 Jul 21 ;8(7). Epub 2016 Jul 21. PMID:
27455313
Article Published Date
: Jul 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Barley
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Bees' honey attenuation of metanil-yellow-induced hepatotoxicity in rats.
Dec 31, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2013 ;2013:614580. Epub 2013 Jun 3. PMID:
23818929
Article Published Date
: Dec 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Metanil-Yellow Dye
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beeswax contains long-chain alcohols which have a preventive effect against chemically-induced liver damage in mice.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2007 Jun;10(2):379-83. PMID:
17651079
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Beeswax
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Beetroot juice prevents adverse changes associated with chemically-induced mammary cancer promotion.
Feb 28, 2013
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2013 Mar 1. Epub 2013 Mar 1. PMID:
23450834
Article Published Date
: Feb 28, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Chemopreventive
Adverse Pharmacological Actions
:
Carcinogenic
[+]
Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats.
May 31, 2012
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2012 Jun ;50(6):2027-33. Epub 2012 Mar 24. PMID:
22465004
Article Published Date
: May 31, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
,
DNA damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
N-nitrosodiethylamine
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Beetroot protects the liver against chemical toxicity.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2006 Feb;77(2):91-3. Epub 2005 Dec 20. PMID:
16376022
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Beet
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Berberine exerts a protective action against carbon tetrachloride induced acute liver injury.
Aug 05, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2019 Aug 6. Epub 2019 Aug 6. PMID:
31432116
Article Published Date
: Aug 05, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
[+]
Berberine exhibits notable preventive effects on acetaminophen induced hepatotoxicity.
Jun 30, 2018
Click here to read the entire abstract
Pubmed Data
: Biomed Pharmacother. 2018 Jul ;103:1319-1326. Epub 2018 May 7. PMID:
29864914
Article Published Date
: Jun 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Berberine protects against the hepatic damage induced by Paracetamol
Feb 01, 2000
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2000 Feb ;71(1):25-33. PMID:
11449466
Article Published Date
: Feb 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Berberine
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Paracetamol
[+]
Betanin exerted a potential anti-inflammatory and antioxidant effect against hepato-renal damage induced by paracetamol and diclofenac over consumption.
Nov 25, 2019
Click here to read the entire abstract
Pubmed Data
: Biomarkers. 2019 Nov 26:1-24. Epub 2019 Nov 26. PMID:
31766895
Article Published Date
: Nov 25, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Betanin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Diclofenac
,
Paracetamol
[+]
Bile acid conjugate prevents Oxaliplatin chemotherapy-induced fatty liver.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Cancer. 2010 Jan 1;116(1):251-5. PMID:
19890960
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Bile salts
Diseases
:
Chemotherapy-Induced Liver Toxicity
,
Chemotherapy-Induced Toxicity
,
Chemotherapy-Induced Toxicity: Oxaliplatin
,
Fatty Liver
[+]
Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury.
Aug 31, 2016
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2016 Sep ;38:324-31. Epub 2016 Jun 23. PMID:
27344638
Article Published Date
: Aug 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Biochanin A
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Interleukin-1 beta downregulation
,
Nrf2 activation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Bisphenol A causes liver damage and selectively alters the neurochemical coding of intrahepatic parasympathetic nerves in juvenile porcine models.
Dec 14, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Dec 15 ;18(12). Epub 2017 Dec 15. PMID:
29244763
Article Published Date
: Dec 14, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Prenatal Chemical Exposures
Problem Substances
:
Bisphenol A
[+]
Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis.
Aug 26, 2019
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2019 Aug 27 ;133:110786. Epub 2019 Aug 27. PMID:
31470036
Article Published Date
: Aug 26, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Hepatic Steatosis
,
Prenatal Chemical Exposures
Additional Keywords
:
Increased Risk
Problem Substances
:
Bisphenol A
[+]
Bisphenol A induced oxidative stress, inflammatory response, apoptosis and mitochondrial dysfunction in mouse colons and livers.
Aug 31, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomed Pharmacother. 2019 Sep ;117:109182. Epub 2019 Jul 1. PMID:
31387175
Article Published Date
: Aug 31, 2019
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Bisphenol A promotes hepatic lipid deposition involving Kupffer cell M1 polarization in male mice.
May 11, 2017
Click here to read the entire abstract
Pubmed Data
: J Endocrinol. 2017 May 12. Epub 2017 May 12. PMID:
28500084
Article Published Date
: May 11, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
Problem Substances
:
Bisphenol A
Adverse Pharmacological Actions
:
Hepatotoxic
[+]
Bisphenol S-induced chronic inflammatory stress in liver.
Feb 28, 2019
Click here to read the entire abstract
Pubmed Data
: Environ Pollut. 2019 Mar ;246:963-971. Epub 2018 Dec 24. PMID:
31159146
Article Published Date
: Feb 28, 2019
Study Type
: Animal Study, In Vitro Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Inflammation
,
Liver Damage
,
Oxidative Stress
Problem Substances
:
Bisphenol S
[+]
Bitter apple fruit possess significant hepatoprotective and antioxidant activity.
Apr 30, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 May ;28(3):951-7. PMID:
26004728
Article Published Date
: Apr 30, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Bitter Apple
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Phytotherapy
,
Plant Extracts
Problem Substances
:
Paracetamol
[+]
Black garlic exhibited significant protective effects on carbon tetrachloride-induced acute hepatic injury.
Mar 19, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Molecules. 2019 Mar 20 ;24(6). Epub 2019 Mar 20. PMID:
30897831
Article Published Date
: Mar 19, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Fermented Foods and Beverages
,
Garlic
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Black tea extract has a protective effect on the levels of lipid peroxidation and antioxidant enzymes in liver of mice with pesticide-induced liver injury.
Jul 01, 2006
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2006 Jul-Aug;24(4):327-32. PMID:
15991261
Article Published Date
: Jul 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Black Tea
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
,
Pesticide Toxicity
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Blueberries have preventive effect on carbon tetrachloride-induced hepatic fibrosis.
Aug 19, 2018
Click here to read the entire abstract
Pubmed Data
: Zhonghua Gan Zang Bing Za Zhi. 2018 Aug 20 ;26(8):590-595. PMID:
30317790
Article Published Date
: Aug 19, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Blueberry components could regulate histone acetylation and improve liver pathologic changes in rats with carbon tetrachloride-induced disease.
Feb 15, 2017
Click here to read the entire abstract
Pubmed Data
: Genet Mol Res. 2017 Feb 16 ;16(1). Epub 2017 Feb 16. PMID:
28218781
Article Published Date
: Feb 15, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Disease
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Blueberry prevents chemically-induced hepatic fibrosis in rats.
Jun 07, 2010
Click here to read the entire abstract
Pubmed Data
: World J Gastroenterol. 2010 Jun 7;16(21):2657-63. PMID:
20518088
Article Published Date
: Jun 07, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Blueberry
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
[+]
Both Nigella sativa and date reduce the toxic effects of aflatoxin-B1 in liver and kidney.
Jun 30, 2008
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Health Sci (Qassim). 2008 Jul ;2(2):26-44. PMID:
21475486
Article Published Date
: Jun 30, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Dates
,
Nigella sativa (aka Black Seed)
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
Problem Substances
:
Aflatoxin
[+]
Boysenberry anthocyanins is a food component available to prevent liver injury.
Dec 31, 2003
Click here to read the entire abstract
Pubmed Data
: Biofactors. 2004 ;21(1-4):259-61. PMID:
15630207
Article Published Date
: Dec 31, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Anthocyanins
,
Berries: All
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Phytotherapy
[+]
BPA has a significant impact on the liver miRNome and transcriptome in adult zebrafish.
Oct 12, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Genes (Basel). 2017 Oct 13 ;8(10). Epub 2017 Oct 13. PMID:
29027980
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Liver Cancer
Additional Keywords
:
Risk Factors
Problem Substances
:
Bisphenol A
[+]
BPA induced liver fibrosis, which is related to the stimulation of the inflammatory response.
Dec 06, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Exp Pathol. 2016 Dec 7. Epub 2016 Dec 7. PMID:
27925325
Article Published Date
: Dec 06, 2016
Study Type
: Animal Study
Additional Links
Diseases
:
Bisphenol Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
,
Liver Fibrosis
,
Oxidative Stress
Problem Substances
:
Bisphenol A
[+]
Brazilian green propolis suppresses acetaminophen-induced hepatocellular necrosis.
Sep 30, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Toxicol Pathol. 2018 Oct ;31(4):275-282. Epub 2018 Jul 1. PMID:
30393431
Article Published Date
: Sep 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Propolis: Brazillian
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Brewer's yeast (S. cerevisiae) has a protective effect against chemically-induced liver damage in rats.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: Clin Nutr. 2009 Jun;28(3):338-45. Epub 2009 Feb 23. PMID:
19233522
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Yeast
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Broccoli sprout extract protected the liver from various types of xenobiotic substances through induction of detoxification enzymes and glutathione synthesis.
Sep 20, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: World J Gastroenterol. 2015 Sep 21 ;21(35):10091-103. PMID:
26401074
Article Published Date
: Sep 20, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Broccoli Sprouts
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Phase I Detoxification Enzyme Inducer
,
Phase II Detoxification Enzyme Inducer
Additional Keywords
:
Gene Expression Regulation
,
Plant Extracts
Problem Substances
:
Acetaminophen
[+]
Bromelain ameliorates hepatic microcirculation after warm ischemia indicating it may have liver protective effects after injury.
May 01, 2007
Click here to read the entire abstract
Pubmed Data
: J Surg Res. 2007 May 1;139(1):88-96. Epub 2007 Feb 8. PMID:
17292418
Article Published Date
: May 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Bromelain
Diseases
:
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Butterbur extract improves lipid profiles and antioxidant activities in monosodium L-glutamate-challenged mice.
Sep 30, 2010
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2010 Oct ;13(5):1216-23. PMID:
20828319
Article Published Date
: Sep 30, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Butterbur
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anticholesteremic Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Monosodium Glutamate (MSG)
[+]
Butylated hydroxytoluene (BHT) exhibits liver toxicity in rats.
Apr 01, 1999
Click here to read the entire abstract
Pubmed Data
: Histol Histopathol. 1999 Apr;14(2):391-406. PMID:
10212800
Article Published Date
: Apr 01, 1999
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
Butylated hydroxytoluene (BHT) potentiates vitamin A induced liver damage in rats.
Aug 01, 1987
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 1987 Aug;90(1):1-9. PMID:
3629584
Article Published Date
: Aug 01, 1987
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Additional Keywords
:
Drug-Plant-Vitamin Synergies
Problem Substances
:
Butylated Hydroxytoluene (BHT)
[+]
C. longa administration decreased HSC activation and ameliorated hepatotoxic changes caused by cadmium in adult rats.
Jan 20, 2016
Click here to read the entire abstract
Pubmed Data
: Biotech Histochem. 2016 Jan 21:1-12. Epub 2016 Jan 21. PMID:
26796199
Article Published Date
: Jan 20, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Turmeric
Diseases
:
Cadmium Poisoning
,
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
[+]
Caffeic acid phenethyl ester should be considered in the prevention of oxidative stress in diabetic liver.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Bratisl Lek Listy. 2016 ;117(5):276-82. PMID:
27215964
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Caffeic acid phenethyl ester
Diseases
:
Diabetic Complications
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
[+]
Camel milk either alone or in combination with bee honey ameliorated the toxic effects of carbon tetrachloride.
May 29, 2016
Click here to read the entire abstract
Pubmed Data
: Can J Physiol Pharmacol. 2016 May 30:1-10. Epub 2016 May 30. PMID:
27455095
Article Published Date
: May 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Camel Milk
,
Honey
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
Pharmacological Actions
:
Anti-Fibrotic
,
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Cannabidiol exhibits therapeutic potential against ischemia/reperfusion liver injury in rats.
Nov 16, 2011
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2011 Nov 16 ;670(1):216-23. Epub 2011 Sep 14. PMID:
21930120
Article Published Date
: Nov 16, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Cannabidiol
Diseases
:
Liver Damage
,
Liver Injury: Ischemia/reperfusion
Pharmacological Actions
:
Hepatoprotective
[+]
Carnosic acid attenuates arsenic-induced hepatotoxicity.
Dec 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2018 ;2018:1421438. Epub 2018 May 2. PMID:
29854073
Article Published Date
: Dec 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Carnosic Acid
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Arsenic
[+]
Carob honey has high antioxidant content, antioxidant property, and protective effect against carbon tetrachloride induced kidney and liver toxicity.
Oct 16, 2018
Click here to read the entire abstract
Pubmed Data
: Arch Med Res. 2018 Oct 17. Epub 2018 Oct 17. PMID:
30342848
Article Published Date
: Oct 16, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Honey
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Renoprotective
[+]
Carrot extract protects the liver from chemical injury.
Jul 07, 1995
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 1995 Jul 7;47(2):69-74. PMID:
7500638
Article Published Date
: Jul 07, 1995
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Carthamus red may serve as a candidate with strong a hepatoprotective effect and antioxidant activity in liver damage.
Jul 08, 2013
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2013 Jul 9 ;148(2):570-8. Epub 2013 May 14. PMID:
23684718
Article Published Date
: Jul 08, 2013
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Safflower
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
Additional Keywords
:
Plant Extracts
[+]
Carvacrol normalizes elevated liver enzymes induced by d-galactosamine-induced hepatotoxicity in rats.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Fundam Clin Pharmacol. 2009 Dec;23(6):757-65. Epub 2009 Jul 24. PMID:
19650854
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Carvacrol suppresses the progression of liver fibrosis.
Jan 31, 2019
Click here to read the entire abstract
Pubmed Data
: Immunopharmacol Immunotoxicol. 2019 Feb ;41(1):163-171. Epub 2019 Feb 1. PMID:
30706740
Article Published Date
: Jan 31, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Carvacrol
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Celery extract protects against pesticide-induced toxicity.
Nov 01, 2011
Click here to read the entire abstract
Pubmed Data
: Hum Exp Toxicol. 2011 Nov 1. Epub 2011 Nov 1. PMID:
22045891
Article Published Date
: Nov 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Celery
,
Flavonoids
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide-Induced Toxicity: Organophosphates
,
Pesticide Toxicity
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Dichlorvos
,
Organophosphates
,
Pesticides
Adverse Pharmacological Actions
:
Hepatotoxic
,
Oxidant
[+]
Celosia cristata extract prevented oxidative stress-induced liver injury by enhancing hepatocyte antioxidant abilities.
Jan 31, 2015
Click here to read the entire abstract
Pubmed Data
: Food Chem. 2015 Feb 1 ;168:572-9. Epub 2014 Jul 31. PMID:
25172750
Article Published Date
: Jan 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Celosia cristata (cockscomb)
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Centella asiantica has a protective effect against acute liver injury in mice.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: Phytomedicine. 2010 Feb 17. Epub 2010 Feb 17. PMID:
20171071
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Centella asiatica
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Centella asiatica may be useful in preventing liver damage.
Oct 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Mol Med Rep. 2016 Nov ;14(5):4521-4528. Epub 2016 Oct 5. PMID:
27748812
Article Published Date
: Oct 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Gotu Kola
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Interleukin-10 downregulation
,
Interleukin-12 downregulation
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Malondialdehyde Down-regulation
,
Superoxide Dismutase Up-regulation
[+]
Chemical characteristics, antioxidant capacities and hepatoprotection of polysaccharides from pomegranate peel.
Dec 14, 2018
Click here to read the entire abstract
Pubmed Data
: Carbohydr Polym. 2018 Dec 15 ;202:461-469. Epub 2018 Sep 7. PMID:
30287023
Article Published Date
: Dec 14, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Pomegranate Peel
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Chickpea extract exhibits a significant hepatoprotective effect against carbon tetrachloride induced liver injury in rats.
Dec 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Front Pharmacol. 2016 ;7:344. Epub 2016 Sep 28. PMID:
27733831
Article Published Date
: Dec 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Chickpea
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Chicory ameliorates nitrosamine precusor induced oxidative stress and liver injury.
Aug 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2163-9. Epub 2010 May 15. PMID:
20478349
Article Published Date
: Aug 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chicory
Diseases
:
Chemically-Induced Liver Damage
,
Nitrosamnine-induced Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Chinese cabbage powder effectively reduced the incidence of liver tumour induced by aflatoxin B1 from 6.67% to 0% in animals.
Oct 31, 2015
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Food Chem. 2015 Nov 1 ;186:13-9. Epub 2015 Mar 6. PMID:
25976785
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Cabbage
Diseases
:
Liver Cancer: Prevention
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Anticarcinogenic Agents
Additional Keywords
:
Risk Reduction
[+]
Chlorella has hepatoprotective properties against tetrachloride-induced oxidative damage in rats.
Sep 01, 2009
Click here to read the entire abstract
Pubmed Data
: In Vivo. 2009 Sep-Oct;23(5):747-54. PMID:
19779110
Article Published Date
: Sep 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Chlorella vulgaris extract ameliorates carbon tetrachloride-induced acute hepatic injury in mice.
Jul 07, 2011
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2011 Jul 7. Epub 2011 Jul 7. PMID:
21741806
Article Published Date
: Jul 07, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Chlorella (Algae)
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
Pharmacological Actions
:
Glutathione Upregulation
,
Hepatoprotective
[+]
Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice.
Jan 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Redox Biol. 2017 Feb 1 ;11:701-707. Epub 2017 Feb 1. PMID:
28187322
Article Published Date
: Jan 31, 2017
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
Problem Substances
:
Aspartame
[+]
Chronic inhalation of e-cigarette vapor may lead to increased inflammation, organ damage, and cardiorenal and hepatic disease.
Jan 30, 2018
Click here to read the entire abstract
Pubmed Data
: Am J Physiol Regul Integr Comp Physiol. 2018 Jan 31. Epub 2018 Jan 31. PMID:
29384700
Article Published Date
: Jan 30, 2018
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
Problem Substances
:
Electronic Cigarettes
[+]
Chrysanthemum indicum might be an alternative and promising agent for the treatment of aging and age-associated brain and liver diseases
Jan 01, 2019
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2019 Jan 2. Epub 2019 Jan 2. PMID:
30610932
Article Published Date
: Jan 01, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Chrysanthemum Indicum
Diseases
:
Aging: Brain
,
Brain Inflammation
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Neuroprotective Agents
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Chrysin has a positive influence on hepatic marker enzymes in chemically-induced liver toxicity in rats.
Mar 31, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Mar 31. Epub 2010 Mar 31. PMID:
20362027
Article Published Date
: Mar 31, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Chrysin
Diseases
:
ALT: Elevated
,
Chemically-Induced Liver Damage
,
Gamma-glutamyl transpeptidase: Elevated
,
GGT
,
Results for Liver Enzymes: Elevated AST
Pharmacological Actions
:
Hepatoprotective
[+]
Cissus quadrangularis protects gainst isoniazid-induced liver damage in rats.
Dec 01, 2010
Click here to read the entire abstract
Pubmed Data
: Indian J Pharmacol. 2010 Dec;42(6):397-400. PMID:
21189914
Article Published Date
: Dec 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cissus quadrangularis
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity
,
Tuberculosis Drug Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Citrus maxima peel powder produced significant hepatoprotective action in carbon tetrachloride administered rats.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Evid Based Complement Alternat Med. 2015 ;2015:598179. Epub 2015 May 28. PMID:
26106435
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Citrus Peel
Diseases
:
Chemically-Induced Liver Damage
,
Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Cloudy apple juice potentiates hepatoprotection during experimental liver injury.
Aug 20, 2019
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2019 Aug 21 ;140:1006-1017. Epub 2019 Aug 21. PMID:
31445146
Article Published Date
: Aug 20, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Apple
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cyclooxygenase 2 Inhibitors
,
Hepatoprotective
[+]
Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.
Jun 24, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: BMC Complement Altern Med. 2018 Jun 25 ;18(1):195. Epub 2018 Jun 25. PMID:
29940935
Article Published Date
: Jun 24, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Coconut Water
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Colocasia esculenta possesses hepatoprotective activity against thioacetamide in rats.
Oct 31, 2015
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2015 Nov ;28(6 Suppl):2237-41. PMID:
26687753
Article Published Date
: Oct 31, 2015
Study Type
: Animal Study
Additional Links
Substances
:
Taro
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Combinatorial usage of fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum ameliorate drug-induced liver injury in mice.
Aug 31, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Sep ;119:66-72. Epub 2018 May 16. PMID:
29753871
Article Published Date
: Aug 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
,
Medicinal Mushrooms
Diseases
:
Chemotherapy-Induced Toxicity: Cyclophosphamide
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Apoptotic
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Polysaccharides
[+]
Comparative hepatoprotective effect of Nigella sativa pre- and post-treatment.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Pak J Pharm Sci. 2019 Jan ;32(1):205-212. PMID:
30772810
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Nigella sativa (aka Black Seed)
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Prophylactic Agents
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Cordyceps exhibits potent hepatoprotective properties in an animal model.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Fitoterapia. 2010 Jan;81(1):1-7. Epub 2009 Jul 8. PMID:
19596425
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Cordyceps sinensis
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Coriandrum sativum has a protective effect on carbon tetrachloride-induced hepatotoxicity in mice.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2009 Apr;47(4):702-8. Epub 2008 Dec 29. PMID:
19146910
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Coriandrum sativum
Diseases
:
Chemotherapy-Induced Liver Toxicity
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Cow urine distillate attenuates chemically-induced liver damage in rats.
Aug 01, 2009
Click here to read the entire abstract
Pubmed Data
: Biomed Environ Sci. 2009 Aug;22(4):345-7. PMID:
19950531
Article Published Date
: Aug 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Urine
,
Urine: Cow
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
[+]
Cranberry extract exhibits promising hepatoprotective potential against the chemical induced hepatotoxicity.
Oct 31, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Med. 2017 Nov ;10(11):1054-1058. Epub 2017 Oct 27. PMID:
29203101
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cranberry
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.
May 31, 2015
Click here to read the entire abstract
Pubmed Data
: Cell Biochem Funct. 2015 Jun ;33(4):202-10. Epub 2015 May 11. PMID:
25962994
Article Published Date
: May 31, 2015
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Cranberry
,
Flavonoids
Diseases
:
Lipid Peroxidation
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Crocin administration could protect the liver damage induced by morphine.
Feb 29, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Res Pharm Sci. 2016 Mar-Apr;11(2):120-9. PMID:
27168751
Article Published Date
: Feb 29, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Crocin
Diseases
:
Liver Damage: Drug-Induced
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
Problem Substances
:
Morphine
[+]
Crocus sativus could effectively alleviate methotrexate-induced hepatotoxicity.
Oct 25, 2019
Click here to read the entire abstract
Pubmed Data
: J Complement Integr Med. 2019 Oct 26. Epub 2019 Oct 26. PMID:
31675349
Article Published Date
: Oct 25, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Drug-Induced Toxicity: Methotrexate
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Crocus sativus hydroalcoholic extract has beneficial effects on inflammatory and enzymatic indices resulting from alcohol use in kidney and liver.
Dec 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Inflamm Res. 2019 ;12:269-283. Epub 2019 Oct 8. PMID:
31632125
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Saffron
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Cucurbitacin-B attenuates carbon tetrachloride induced hepatic fibrosis in mice through inhibition of STAT-3.
Dec 16, 2017
Click here to read the entire abstract
Pubmed Data
: Chem Biol Drug Des. 2017 Dec 17. Epub 2017 Dec 17. PMID:
29250925
Article Published Date
: Dec 16, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Cucurbitacin B
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Hepatoprotective
,
STAT3 Inhibitor
[+]
Curcuma longa extract or curcumin has the ability to alleviate the hepatotoxic effects caused by mercuric chloride in rats.
Mar 19, 2017
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2017 Mar 20. Epub 2017 Mar 20. PMID:
28336172
Article Published Date
: Mar 19, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
Problem Substances
:
Mercury
[+]
Curcumin administration ameliorated the induced effects of aflatoxin B1.
Dec 31, 2014
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Phytother Res. 2015 Jan ;29(1):134-40. Epub 2014 Oct 8. PMID:
25639897
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Lipid Peroxidation
,
Liver Damage: Aflatoxin-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
[+]
Curcumin ameliorates acute thioacetamide-induced hepatotoxicity.
Feb 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Gastroenterol Hepatol. 2006 Feb;21(2):358-66. PMID:
16509859
Article Published Date
: Feb 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Enzyme Inhibitors
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Curcumin ameliorates aflatoxin-induced changes in SDH and ATPase activities in liver and kidney of mice.
Jul 01, 2008
Click here to read the entire abstract
Pubmed Data
: Acta Pol Pharm. 2008 Jul-Aug;65(4):415-9. PMID:
19051581
Article Published Date
: Jul 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Aflatoxicosis
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
,
Renoprotective
[+]
Curcumin ameliorates chemically-induced liver damage and fibrosis in rats.
Oct 01, 2011
Click here to read the entire abstract
Pubmed Data
: Ann Hepatol. 2011 Oct 1 ;10(4):516-30. PMID:
21911894
Article Published Date
: Oct 01, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin ameliorates endotoxin-induced experimental hepatoxicity in rodents.
Aug 01, 2006
Click here to read the entire abstract
Pubmed Data
: Clin Exp Immunol. 2006 Aug;145(2):313-21. PMID:
16879252
Article Published Date
: Aug 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin ameliorates lead-induced hepatotoxicity.
Nov 04, 2019
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Biomolecules. 2019 Nov 5 ;9(11). Epub 2019 Nov 5. PMID:
31694300
Article Published Date
: Nov 04, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Lead
[+]
Curcumin and capsaicin individually are protective to LDL oxidation both in vivo and in vitro, to iron-induced hepatotoxicity and to carrageenan-induced inflammation.
Aug 26, 2009
Click here to read the entire abstract
Pubmed Data
: J Agric Food Chem. 2009 Aug 26;57(16):7401-8. PMID:
16956363
Article Published Date
: Aug 26, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Capsaicin
,
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Cholesterol: Oxidation
,
Inflammation
,
Iron Poisoning
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Natural Substance Synergy
[+]
Curcumin and NAC protect against valproate-induced liver toxicity.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Arzneimittelforschung. 2010;60(11):647-53. PMID:
21175036
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
NAC (N-acetyl-L-cysteine)
Diseases
:
Chemically-Induced Liver Damage
,
Drug-Induced Toxicity: Valproic Acid (Depakote)
Pharmacological Actions
:
Anticonvulsants
,
Antioxidants
,
Hepatoprotective
[+]
Curcumin and saikosaponin A inhibit chemical-induced liver inflammation and fibrosis in rats.
Jul 24, 2007
Click here to read the entire abstract
Pubmed Data
: Mol Vis. 2007 Jul 24;13:1291-7. PMID:
20128048
Article Published Date
: Jul 24, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Saikosaponin
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis
,
Inflammation
,
Liver Fibrosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
NF-kappaB Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Curcumin and selenium can hinder the progression and severity of liver injury during acute inflammatory episodes.
Oct 24, 2019
Click here to read the entire abstract
Pubmed Data
: Biol Trace Elem Res. 2019 Oct 25. Epub 2019 Oct 25. PMID:
31654258
Article Published Date
: Oct 24, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Selenium
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Diclofenac
[+]
Curcumin and turmeric extract might be recommendable to recover liver activity.
Jul 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Sci Rep. 2017 Jul 26 ;7(1):6513. Epub 2017 Jul 26. PMID:
28747775
Article Published Date
: Jul 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Turmeric
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats
Aug 01, 2007
Click here to read the entire abstract
Pubmed Data
: Zhonghua Er Ke Za Zhi. 2007 Aug;45(8):604-8. PMID:
18021535
Article Published Date
: Aug 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Copper Toxicity
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Curcumin attenuates alcohol toxicity.
Aug 20, 2004
Click here to read the entire abstract
Pubmed Data
: J Pharm Pharm Sci. 2004 Aug 20;7(2):274-83. Epub 2004 Aug 20. PMID:
15367386
Article Published Date
: Aug 20, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin attenuates Concanavalin A-induced liver injury in mice.
Dec 31, 2011
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2012 Jan ;12(1):151-7. Epub 2011 Dec 2. PMID:
22138522
Article Published Date
: Dec 31, 2011
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Hepatitis: Lectin-Induced (concanavalin)
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
[+]
Curcumin attenuates dimethylnitrosamine-induced liver injury in rats.
Apr 01, 2008
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2008 Apr;46(4):1279-87. Epub 2007 Sep 26. PMID:
18006204
Article Published Date
: Apr 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Anticarcinogenic Agents
,
Hepatoprotective
[+]
Curcumin effectively protects against zinc oxide nanoparticle induced hepatotoxicity in rats.
Apr 30, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Balkan Med J. 2016 May ;33(3):252-7. Epub 2016 May 1. PMID:
27308068
Article Published Date
: Apr 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
Problem Substances
:
Nanoparticles
[+]
Curcumin has a liver protecting effect against aflatoxin B(1)-induced liver injury.
May 01, 2010
Click here to read the entire abstract
Pubmed Data
: Arch Toxicol. 2010 May;84(5):389-96. Epub 2010 Jan 30. PMID:
20112103
Article Published Date
: May 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Aflatoxicosis
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Stilbenes
[+]
Curcumin has a protective effect against nicotine-induced genotoxicity on rat liver.
Jul 07, 2008
Click here to read the entire abstract
Pubmed Data
: Eur J Pharmacol. 2008 Jul 7;588(2-3):151-7. Epub 2008 Apr 15. PMID:
18508046
Article Published Date
: Jul 07, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
DNA damage
,
Nicotine/Tobacco Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin has a protective effect on experimentally induced inflammation, hepatotoxicity and cardiotoxicity in rats.
Apr 02, 2010
Click here to read the entire abstract
Pubmed Data
: Exp Toxicol Pathol. 2010 Apr 2. Epub 2010 Apr 2. PMID:
20363603
Article Published Date
: Apr 02, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Cardiovascular Diseases
,
Inflammation
,
Liver Damage: Drug-Induced
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Cardioprotective
,
Hepatoprotective
[+]
Curcumin induces recovery from hepatic injury.
Oct 01, 2008
Click here to read the entire abstract
Pubmed Data
: Indian J Biochem Biophys. 2008 Oct;45(5):317-25. PMID:
19069843
Article Published Date
: Oct 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
Pharmacological Actions
:
Apoptotic
,
Hepatoprotective
[+]
Curcumin inhibits chemically-induced liver cancer.
Nov 01, 2000
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2000 Nov;38(11):991-5. PMID:
11038236
Article Published Date
: Nov 01, 2000
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Chemopreventive
,
Hepatoprotective
,
NF-kappaB Inhibitor
,
Tumor Suppressor Protein p53 Upregulation
[+]
Curcumin intervention ameliorates the AFB(1) induced toxicity.
Feb 17, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Feb 17;127(3):641-4. Epub 2009 Dec 14. PMID:
20015472
Article Published Date
: Feb 17, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Aflatoxicosis
,
Chemically-Induced Liver Damage
,
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Plant Extracts
[+]
Curcumin prevents chemically-induced liver cancer.
Mar 30, 2007
Click here to read the entire abstract
Pubmed Data
: Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):439-42. Epub 2006 Dec 15. PMID:
10657978
Article Published Date
: Mar 30, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cancer
Pharmacological Actions
:
Anticarcinogenic Agents
,
Chemopreventive
[+]
Curcumin prevents liver fibrosis.
Oct 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Nat Med. 2009 Oct;63(4):415-20. Epub 2009 Jun 25. PMID:
19554395
Article Published Date
: Oct 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Fibrotic
,
Apoptotic
[+]
Curcumin protects against acetaminophen-induced toxicity.
Jan 16, 2012
Click here to read the entire abstract
Pubmed Data
: Curr Neurovasc Res. 2012 Jan 16. Epub 2012 Jan 16. PMID:
22272768
Article Published Date
: Jan 16, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Apoptotic
,
Hepatoprotective
[+]
Curcumin protects against acute liver damage in the rat.
Jun 01, 2007
Click here to read the entire abstract
Pubmed Data
: Biochim Biophys Acta. 2007 Jun;1770(6):989-96. Epub 2007 Feb 22. PMID:
17383825
Article Published Date
: Jun 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
NF-kappaB Inhibitor
[+]
Curcumin protects against alcohol and oxidized fat-induced liver toxicity.
Jul 01, 2004
Click here to read the entire abstract
Pubmed Data
: Ital J Biochem. 2004 Jul;53(2):61-6. PMID:
15646009
Article Published Date
: Jul 01, 2004
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Matrix metalloproteinase-2 (MMP-2) inhibitor
[+]
Curcumin protects against chemically-induced liver damage in rats.
Apr 04, 2006
Click here to read the entire abstract
Pubmed Data
: Life Sci. 2006 Apr 4;78(19):2188-93. Epub 2005 Nov 8. PMID:
16288784
Article Published Date
: Apr 04, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin protects against chemically-induced rat liver injury.
Mar 20, 2005
Click here to read the entire abstract
Pubmed Data
: Int J Cancer. 2005 Mar 20;114(2):190-4. PMID:
10813555
Article Published Date
: Mar 20, 2005
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects against cigarette smoke and ethanol-induced lipid alterations in rat lung and liver.
Jun 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Appl Microbiol. 2009 Jun;106(6):2086-95. Epub 2009 Mar 9. PMID:
16691314
Article Published Date
: Jun 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lung Damage
,
Nicotine/Tobacco Toxicity
,
Oxidative Stress
,
Smoking
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects against doxorubicin (adriamycin)-induced toxicity in rats.
Apr 01, 2009
Click here to read the entire abstract
Pubmed Data
: J Med Food. 2009 Apr;12(2):394-402. PMID:
19459743
Article Published Date
: Apr 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Chemotherapy-Induced Toxicity: Doxorubicin
Pharmacological Actions
:
Antioxidants
Additional Keywords
:
Drug: Doxorubicin
,
Drug Side Effect Attenuation
,
Plant Extracts
[+]
Curcumin protects against endotoxin-induced acute liver injury in rats.
Jan 01, 2006
Click here to read the entire abstract
Pubmed Data
: J Huazhong Univ Sci Technolog Med Sci. 2006;26(6):678-81. PMID:
17357487
Article Published Date
: Jan 01, 2006
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Endotoxemia
,
Liver Damage
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects against experimental liver injury in mice.
Aug 01, 2003
Click here to read the entire abstract
Pubmed Data
: Zhongguo Zhong Yao Za Zhi. 2003 Aug;28(8):756-8, 793. PMID:
15015361
Article Published Date
: Aug 01, 2003
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects against hepatic and renal injury.
Dec 18, 2009
Click here to read the entire abstract
Pubmed Data
: Microsc Res Tech. 2009 Dec 18. Epub 2009 Dec 18. PMID:
20025056
Article Published Date
: Dec 18, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Kidney Damage
[+]
Curcumin protects against intestinal origin endotoxemia in rat liver cirrhosis.
Feb 13, 2017
Click here to read the entire abstract
Pubmed Data
: J Food Sci. 2017 Feb 14. Epub 2017 Feb 14. PMID:
28196290
Article Published Date
: Feb 13, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Liver Cirrhosis
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Interleukin-6 Downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Gene Expression Regulation
[+]
Curcumin protects the liver against aflatoxin-induced changes.
Dec 01, 2009
Click here to read the entire abstract
Pubmed Data
: Poult Sci. 2009 Dec;88(12):2620-7. PMID:
19903961
Article Published Date
: Dec 01, 2009
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
[+]
Curcumin protects the rat liver from chemically-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation.
Feb 01, 2008
Click here to read the entire abstract
Pubmed Data
: Mol Pharmacol. 2008 Feb;73(2):399-409. Epub 2007 Nov 15. PMID:
18006644
Article Published Date
: Feb 01, 2008
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
curcumin reduces markers of liver damage in rats treated with heated sunflower oil or ethanol.
Jan 01, 2010
Click here to read the entire abstract
Pubmed Data
: Vet Ital. 2010 Jan-Mar;46(1):83-92. PMID:
20391370
Article Published Date
: Jan 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Alcohol Toxicity
,
Liver Damage: Drug-Induced
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Curcumin suppresses chemically-induced oxidative stress in the mouse liver.
Jan 01, 2007
Click here to read the entire abstract
Pubmed Data
: Prog Biophys Mol Biol. 2007 Jan-Apr;93(1-3):295-300. Epub 2006 Aug 22. PMID:
11234915
Article Published Date
: Jan 01, 2007
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Enzyme Inhibitors
,
Hepatoprotective
[+]
Curcumin treatment attenuates liver lesions induced by intestinal ischemia/reperfusion.
Dec 31, 2013
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Oxid Med Cell Longev. 2014 ;2014:191624. Epub 2014 Aug 20. PMID:
25215173
Article Published Date
: Dec 31, 2013
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
Diseases
:
Intestinal Ischemia
,
Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Hepatoprotective
,
Interleukin-6 Downregulation
,
NF-kappaB Inhibitor
,
Superoxide Dismutase Up-regulation
[+]
Dandelion contains compounds which protect against chemically-induced liver toxicity in mice.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Acta Biol Hung. 2010 Jun;61(2):175-90. PMID:
20519172
Article Published Date
: Jun 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Dandelion extract protects against acute, chemically-induced liver injury.
Sep 01, 2010
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2010 Sep;24(9):1347-53. PMID:
20812277
Article Published Date
: Sep 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Chemically-Induced Liver Damage
,
Inflammation
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
Additional Keywords
:
Plant Extracts
[+]
Dandelion has antifibrotic activity in chemically-induced liver damage in mice.
Aug 09, 2010
Click here to read the entire abstract
Pubmed Data
: J Ethnopharmacol. 2010 Aug 9;130(3):569-77. Epub 2010 Jun 2. PMID:
20561925
Article Published Date
: Aug 09, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Chemically-Induced Liver Damage
,
Liver Fibrosis
,
Oxidative Stress
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Plant Extracts
[+]
Dandelion has hepatoprotective effects against alcoholic liver damage.
Jun 01, 2010
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2010 Jun;48(6):1632-7. Epub 2010 Mar 27. PMID:
20347918
Article Published Date
: Jun 01, 2010
Study Type
: Animal Study
Additional Links
Substances
:
Dandelion
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
,
Oxidative Stress
Pharmacological Actions
:
Hepatoprotective
,
Malondialdehyde Down-regulation
Additional Keywords
:
Plant Extracts
[+]
Daucus carota seed extract contributes to the reduction of oxidative stress and the protection of liver in experimental rats.
Apr 30, 2012
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Asian Pac J Trop Biomed. 2012 May ;2(5):385-8. PMID:
23569935
Article Published Date
: Apr 30, 2012
Study Type
: Animal Study
Additional Links
Substances
:
Carrot
Diseases
:
Chemically-Induced Liver Damage
,
Lipid Peroxidation
,
Oxidative Stress
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Superoxide Dismutase Up-regulation
Additional Keywords
:
Phytotherapy
,
Plant Extracts
[+]
Diallyl sulfide ameliorates carbon tetrachloride-induced hepatotoxicity.
Feb 26, 2019
Click here to read the entire abstract
Pubmed Data
: J Biochem Mol Toxicol. 2019 Feb 27:e22307. Epub 2019 Feb 27. PMID:
30811752
Article Published Date
: Feb 26, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
,
Nrf2 activation
[+]
Diallyl sulfide and curcumin effectively reduced Thallium acetate induced liver toxicity.
Dec 31, 2014
Click here to read the entire abstract
Pubmed Data
: Cell J. 2015 ;17(2):379-88. Epub 2015 Jul 11. PMID:
26199917
Article Published Date
: Dec 31, 2014
Study Type
: Animal Study
Additional Links
Substances
:
Curcumin
,
Diallyl sulfide
Diseases
:
Chemically-Induced Liver Damage
,
Oxidative Stress
,
Thallium Poisoning
Pharmacological Actions
:
Hepatoprotective
[+]
Diallyl sulfide protects against lipopolysaccharide/d-galactosamine-induced acute liver injury.
Jul 30, 2018
Click here to read the entire abstract
Pubmed Data
: Food Chem Toxicol. 2018 Jul 31 ;120:500-509. Epub 2018 Jul 31. PMID:
30075314
Article Published Date
: Jul 30, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Lipopolysaccharide-Induced Toxicity
,
Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
,
Interleukin-1 beta downregulation
,
Tumor Necrosis Factor (TNF) Alpha Inhibitor
[+]
Diallyl sulfide treatment protects against acetaminophen-/carbon tetrachloride-induced acute liver injury.
Dec 31, 2018
Click here to read the entire abstract
Pubmed Data
: Toxicol Res (Camb). 2019 Jan 1 ;8(1):67-76. Epub 2018 Oct 25. PMID:
30713662
Article Published Date
: Dec 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Diallyl sulfide
Diseases
:
Acetaminophen (Tylenol) Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
Problem Substances
:
Acetaminophen
,
Paracetamol
[+]
Dibenzoylmethane protects against carbon tetrachloride induced acute liver injury.
Oct 31, 2017
Click here to read the entire abstract
Pubmed Data
: AAPS J. 2017 Nov ;19(6):1703-1714. Epub 2017 Aug 21. PMID:
28828752
Article Published Date
: Oct 31, 2017
Study Type
: Animal Study, In Vitro Study
Additional Links
Substances
:
Dibenzoylmethane (DBM)
Diseases
:
Chemically-Induced Liver Damage
,
Liver Disease
Pharmacological Actions
:
Antioxidants
,
Heme oxygenase-1 up-regulation
,
Hepatoprotective
,
Nrf2 activation
[+]
Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers.
Aug 31, 2013
Click here to read the entire abstract
Pubmed Data
: Toxicol Appl Pharmacol. 2013 Sep 1 ;271(2):137-43. Epub 2013 May 14. PMID:
23684557
Article Published Date
: Aug 31, 2013
Study Type
: Animal Study
Additional Links
Diseases
:
Chemically-Induced Liver Damage
,
Pesticide Toxicity
Problem Substances
:
Dichloro-diphenyl-trichloroethane (DDT)
[+]
dietary L. casei alleviates LPS-induced liver injury via reducing pro-inflammatory cytokines and increasing anti-oxidative capacity.
Nov 25, 2017
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Mol Sci. 2017 Nov 26 ;18(12). Epub 2017 Nov 26. PMID:
29186870
Article Published Date
: Nov 25, 2017
Study Type
: Animal Study
Additional Links
Substances
:
Lactobacillus casei
Diseases
:
Chemically-Induced Liver Damage
,
Lipopolysaccharide-Induced Toxicity
Pharmacological Actions
:
Anti-Inflammatory Agents
,
Antioxidants
,
Hepatoprotective
[+]
Dietary selenium protected chicks from aflatoxin B1-induced liver injury.
Mar 08, 2016
Click here to read the entire abstract
Pubmed Data
: J Nutr. 2016 Mar 9. Epub 2016 Mar 9. PMID:
26962192
Article Published Date
: Mar 08, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Selenium
Diseases
:
Liver Damage: Aflatoxin-Induced
Pharmacological Actions
:
Hepatoprotective
Additional Keywords
:
Gene Expression Regulation
[+]
Dietary supplementation of vitamin D prevents the development of western diet-induced metabolic, hepatic and cardiovascular abnormalities.
Jul 31, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: United European Gastroenterol J. 2018 Aug ;6(7):1056-1064. Epub 2018 May 17. PMID:
30228894
Article Published Date
: Jul 31, 2018
Study Type
: Animal Study
Additional Links
Substances
:
Vitamin D
Diseases
:
Liver Damage
Pharmacological Actions
:
Cardioprotective
,
Hepatoprotective
Anti Therapeutic Actions
:
Western Diet
[+]
Dietary zerumbone ameliorates hepatotoxin-mediated acute and chronic liver injury.
Apr 30, 2019
Click here to read the entire abstract
Pubmed Data
: Phytother Res. 2019 May ;33(5):1538-1550. Epub 2019 Mar 14. PMID:
30868670
Article Published Date
: Apr 30, 2019
Study Type
: Animal Study
Additional Links
Substances
:
Zerumbone
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Anti-Apoptotic
,
Hepatoprotective
[+]
Dill displayed a potential hepatoprotective effect against carbon tetrachloride induced liver damage.
Mar 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: Int J Appl Basic Med Res. 2016 Apr-Jun;6(2):111-4. PMID:
27127740
Article Published Date
: Mar 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Dill
Diseases
:
Chemically-Induced Liver Damage
Pharmacological Actions
:
Hepatoprotective
,
Malondialdehyde Down-regulation
[+]
Dill with potential antioxidant, antiglycation, and hepatoprotective effects can be suggested for treatment of diabetes complications.
Dec 31, 2016
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.
Pubmed Data
: J Pharm (Cairo). 2017 ;2017:6081374. Epub 2017 Jan 15. PMID:
28182107
Article Published Date
: Dec 31, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Dill
Diseases
:
Advanced Glycation End products (AGE)
,
Chemically-Induced Liver Damage
,
Diabetic Complications
Pharmacological Actions
:
Anti-Glycation Agents
,
Antioxidants
,
Hepatoprotective
Additional Keywords
:
Plant Extracts
[+]
Docosahexaenoic acid attenuates carbon tetrachloride-induced hepatic fibrosis in rats.
Oct 12, 2017
Click here to read the entire abstract
Pubmed Data
: Int Immunopharmacol. 2017 Oct 13 ;53:56-62. Epub 2017 Oct 13. PMID:
29035816
Article Published Date
: Oct 12, 2017
Study Type
: Animal Study
Additional Links
Substances
:
DHA (Docosahexaenoic Acid)
Diseases
:
Chemically-Induced Liver Damage
,
Fibrosis: Liver
Pharmacological Actions
:
Anti-Fibrotic
,
Hepatoprotective
[+]
Dried fig could be used to protect against the production of ethanol-induced free radicals and hepatotoxicity.
Sep 30, 2016
Click here to read the entire abstract
Pubmed Data
: Int J Biol Macromol. 2016 Oct ;91:554-9. Epub 2016 Jun 5. PMID:
27268385
Article Published Date
: Sep 30, 2016
Study Type
: Animal Study
Additional Links
Substances
:
Fig
Diseases
:
Alcohol Toxicity
,
Chemically-Induced Liver Damage
Pharmacological Actions
:
Antioxidants
,
Hepatoprotective
[+]
Dual action of vitamin C in iron supplement therapeutics for iron deficiency anemia: prevention of liver damage induced by iron overload.
Oct 16, 2018
Click here to read the entire abstract
Article Publish Status
: This is a free article.
Click here to read the complete article.