Dental Caries

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65 Substances Researched for Dental Caries
NameACCKFocus
Xylitol12114Locked
Green Tea441Locked
Probiotics423Locked
Black Tea322Locked
Holy Basil422Locked
Bifidobacterium120Locked
Breast Milk 120Locked
Calcium120Locked
Fermented Foods and Beverages120Locked
Lactobacillus paracasei220Locked
Lactobacillus probiotics120Locked
Manuka Honey220Locked
Yoghurt120Locked
Polyphenols312Locked
Bifidobacterium Lactis110Locked
Erythritol110Locked
Flavonoids110Locked
Lactobacillus Acidophilus110Locked
Lactobacillus reuteri110Locked
Licorice110Locked
Mastic gum110Locked
Sour Cherry110Locked
Vitamin D110Locked
Zinc110Locked
yogurt110Locked
Aloe Vera27Locked
Cranberry23Locked
Astaxanthin12Locked
Cranberry Proanthocyanidins12Locked
Fish Oil12Locked
Neem22Locked
Peppermint22Locked
Tea Tree12Locked
Triphala12Locked
Allicin11Locked
Apple11Locked
Baccharis dracunculifolia11Locked
Basil: Sweet11Locked
Bee Propolis11Locked
Berberine11Locked
Carvacrol11Locked
Cinnamon11Locked
Cumin11Locked
Curcumin11Locked
Curry Leaves11Locked
Eucalyptus11Locked
Garlic11Locked
Ginsenosides11Locked
Grape Seed Extract11Locked
Guava11Locked
Hibiscus sabdariffa 11Locked
Magnolia11Locked
Magnolol11Locked
Mangifera indica 11Locked
Mango 11Locked
Noni11Locked
Oregano11Locked
Phyllanthus Muellerianus11Locked
Pomegranate Peel11Locked
Rock-rose11Locked
Rosemary11Locked
Stevia11Locked
Tea11Locked
Thai Herbal Formulations11Locked
Thymol11Locked
10 Problem Substances Researched for Dental Caries
NameACCKFocus
Sodium Fluoride332Locked
Chlorhexidine gluconate230Locked
Fluoride220Locked
Sugar Sweetened Beverages120Locked
Sugar110Locked
Sucrose24Locked
Aspartame12Locked
Fructose12Locked
Sucralose (aka Splenda)12Locked
Antibiotics11Locked
3 Therapeutic Actions Researched for Dental Caries
NameACCKFocus
Breastfeeding120Locked
Gum Chewing220Locked
Light Therapy11Locked
1 Problematic Actions Researched for Dental Caries
NameACCKFocus
Chemotherapy110Locked

View the Evidence:
82 Abstracts with Dental Caries Research

[+]

A variety of probiotics have been studied to reduce dental caries in children. Dec 31, 2007

Pubmed Data : Int J Paediatr Dent. 2008 Jan ;18(1):3-10. PMID: 18086020
Article Published Date : Dec 31, 2007
Study Type : Meta Analysis
Additional Links
Substances : Bifidobacterium, Lactobacillus probiotics, Probiotics
Diseases : Dental Caries: Children
Additional Keywords : Probiotics-oral Health
[+]

A Chinese green tea polyphenol extract has evident anti-plaque effect.Sep 01, 2000

Pubmed Data : Zhonghua Kou Qiang Yi Xue Za Zhi. 2000 Sep;35(5):383-4. PMID: 11780252
Article Published Date : Sep 01, 2000
Study Type : Human Study
Additional Links
Substances : Flavonoids, Green Tea, Polyphenols
Diseases : Dental Caries
[+]

A high consumption of yogurt may be associated with a lower prevalence of dental caries in young children.Jul 01, 2010

Pubmed Data : J Dent. 2010 Jul;38(7):579-83. Epub 2010 Apr 28. PMID: 20433890
Article Published Date : Jul 01, 2010
Study Type : Human Study
Additional Links
Substances : Fermented Foods and Beverages, Yoghurt
Diseases : Dental Caries, Dental Caries: Children
[+]

Black tea could be useful in reducing dental caries.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Ayu. 2015 Jul-Sep;36(3):278-82. PMID: 27313414
Article Published Date : Jun 30, 2015
Study Type : Human Study
Additional Links
Substances : Black Tea
Diseases : Dental Caries: Children
Pharmacological Actions : Antimicrobial
[+]

Breastfeeding, not milk bottle feeding, is associated with reduced risk of early childhood cariesAug 01, 2008

Pubmed Data : Community Dent Oral Epidemiol. 2008 Aug;36(4):363-9. PMID: 19145723
Article Published Date : Aug 01, 2008
Study Type : Human Study
Additional Links
Substances : Breast Milk
Diseases : Dental Caries, Dental Caries: Children
Therapeutic Actions : Breastfeeding
[+]

Chewing gum with sour cherry extract may be useful for the prevention of dental caries.Jul 16, 2018

Pubmed Data : Food Funct. 2018 Jul 17 ;9(7):4008-4016. PMID: 29978173
Article Published Date : Jul 16, 2018
Study Type : Human Study
Additional Links
Substances : Sour Cherry
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Plant Extracts
[+]

Children treated for solid tumors or lymphoma with chemotherapy have increased caries of the primary teeth.Jan 01, 2010

Pubmed Data : Int J Paediatr Dent. 2010 Jan;20(1):15-23. PMID: 20059589
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Diseases : Chemotherapy-Induced Toxicity, Dental Caries, Neuroblastoma
Pharmacological Actions : Antineoplastic Agents
Additional Keywords : Drug Side Effect Attenuation
[+]

Consumption of milk powder containing L. paracasei SD1 resulted in a reduction of both salivary mutans streptococci and delayed new caries development.Jun 30, 2018

Pubmed Data : Acta Odontol Scand. 2018 Jul ;76(5):331-337. Epub 2018 Mar 22. PMID: 29566582
Article Published Date : Jun 30, 2018
Study Type : Human Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Dental Caries: Children, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
[+]

Erythritol and xylitol have similar effects in reducing some risk factors of dental caries.May 01, 2005

Pubmed Data : Caries Res. 2005 May-Jun;39(3):207-15. PMID: 15914983
Article Published Date : May 01, 2005
Study Type : Human Study
Additional Links
Substances : Erythritol, Xylitol
Diseases : Dental Caries
[+]

Fluorosis contributes to a more intense course of caries progression.Dec 31, 2017

Pubmed Data : Wiad Lek. 2018;71(2 pt 2):335-338. PMID: 29786582
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Diseases : Dental Caries, Dental Fluorosis
Additional Keywords : Increased Risk
Problem Substances : Fluoride
[+]

Green tea extract mouthwash has a promising effect in decreasing the count of salivary S. mutans and in the prevention of dental caries.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Pediatr Dent. 2019 Mar-Apr;12(2):133-138. PMID: 31571786
Article Published Date : Feb 28, 2019
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Mouthwash
[+]

Green tea mouth rinse resulted in significant reduction of colony number of salivary Streptococcus mutans and Lactobacillus which is comparable with sodium fluoride mouth rinse.Nov 30, 2011

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent Res J (Isfahan). 2011 Dec ;8(Suppl 1):S58-63. PMID: 23372597
Article Published Date : Nov 30, 2011
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Dental Caries, Dental Plaque
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Mouthwash, Natural Substances Versus Chemicals, Superiority of Natural Substances versus Drugs
Problem Substances : Sodium Fluoride
[+]

High sugar intakes leads to high levels of caries in adults even in those with widespread water fluoridation and the use of fluoridated toothpastes.Dec 31, 2013

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : BMC Public Health. 2014 ;14:863. Epub 2014 Sep 16. PMID: 25228012
Article Published Date : Dec 31, 2013
Study Type : Human Study
Additional Links
Diseases : Dental Caries
Additional Keywords : Dose Response
Problem Substances : Fluoride, Sugar
[+]

Higher consumption of SSBs is associated with higher caries prevalence among Georgia third graders after adjustment for important covariates.Sep 03, 2015

Pubmed Data : J Public Health Dent. 2015 Sep 4. Epub 2015 Sep 4. PMID: 26339945
Article Published Date : Sep 03, 2015
Study Type : Human Study
Additional Links
Diseases : Dental Caries, Dental Caries: Children
Additional Keywords : Increased Risk
Problem Substances : Sugar Sweetened Beverages
[+]

Holy basil was found to be equally effective in reducing periodontal indices as chlorhexidine yet with no side effects.Mar 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Ayurveda Integr Med. 2014 Apr ;5(2):109-16. PMID: 24948862
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Holy Basil
Diseases : Dental Caries, Dental Plaque, Periodontal Diseases
Pharmacological Actions : anti-inflammatory
Additional Keywords : Mouthwash, Superiority of Natural Substances versus Drugs
[+]

Honey-based mouthwash showed a promising antimicrobial effect on dental caries and plaque and gingival scores.Dec 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Indian Soc Periodontol. 2018 Jan-Feb;22(1):34-39. PMID: 29568170
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Manuka Honey
Diseases : Dental Caries
Pharmacological Actions : Antimicrobial
[+]

Improving children's vitamin D status may be an additional preventive consideration to lower the risk for caries.Nov 08, 2015

Pubmed Data : J Dent Res. 2015 Nov 9. Epub 2015 Nov 9. PMID: 26553883
Article Published Date : Nov 08, 2015
Study Type : Human Study
Additional Links
Substances : Vitamin D
Diseases : Dental Caries: Children, Vitamin D Deficiency
Additional Keywords : Risk Factors, Supplementation
[+]

L. acidophilus La5 and Bifidobacterium lactis Bb12 present in the yogurt were effective in reducing the S. mutans levels in saliva.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Appl Basic Med Res. 2018 Apr-Jun;8(2):111-115. PMID: 29744324
Article Published Date : Mar 31, 2018
Study Type : Human Study
Additional Links
Substances : Bifidobacterium Lactis, Lactobacillus Acidophilus, yogurt
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

L. paracasei SD1 may help to decrease the risk of dental caries.Mar 31, 2014

Pubmed Data : Clin Oral Investig. 2014 Apr ;18(3):857-62. Epub 2013 Jul 28. PMID: 23892501
Article Published Date : Mar 31, 2014
Study Type : Human Study
Additional Links
Substances : Lactobacillus paracasei
Diseases : Dental Caries, Steptococcus Mutans Infections
[+]

Long-term use of xylitol-containing chewing-gum can reduce the risk of dental caries.Feb 01, 2008

Pubmed Data : Int Dent J. 2008 Feb;58(1):41-50. PMID: 18350853
Article Published Date : Feb 01, 2008
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Dental Caries: Children
[+]

Manuka honey is as effective as chlorhexidine mouthwash in reducing plaque formation.Oct 01, 2010

Pubmed Data : Contemp Clin Dent. 2010 Oct ;1(4):214-7. PMID: 22114423
Article Published Date : Oct 01, 2010
Study Type : Human Study
Additional Links
Substances : Manuka Honey
Diseases : Dental Caries, Dental Plaque
Additional Keywords : Chemical: Chlorhexidine, Natural Substances Versus Drugs
[+]

Mastic gum has antibacterial activity against Streptococci Mutans, and may prevent caries.Jun 01, 2006

Pubmed Data : Arch Oral Biol. 2006 Jun;51(6):476-81. Epub 2005 Dec 15. PMID: 16343417
Article Published Date : Jun 01, 2006
Study Type : Human Study
Additional Links
Substances : Mastic gum
Diseases : Dental Care, Dental Caries
Pharmacological Actions : Anti-Bacterial Agents
[+]

Maternal calcium supplementation during pregnancy reduces dental caries of children at 12 years of age.Nov 01, 2010

Pubmed Data : Acta Obstet Gynecol Scand. 2010 Nov;89(11):1396-402. Epub 2010 Sep 13. PMID: 20831450
Article Published Date : Nov 01, 2010
Study Type : Human Study
Additional Links
Substances : Calcium
Diseases : Dental Caries, Dental Caries: Children, Prenatal Nutrition , Prenatal Nutrition: Prevention of Problems
[+]

Oral zinc supplementation may contribute to the prevention of dental caries in low socioeconomic level primary school healthy children.Sep 01, 2009

Pubmed Data : Turk J Pediatr. 2009 Sep-Oct;51(5):424-8. PMID: 20112596
Article Published Date : Sep 01, 2009
Study Type : Human Study
Additional Links
Substances : Zinc
Diseases : Dental Caries: Children
[+]

Probiotics consumption may have a beneficial caries-preventive effect.Dec 31, 2017

Pubmed Data : J Clin Pediatr Dent. 2018 ;42(5):331-338. Epub 2018 May 15. PMID: 29763353
Article Published Date : Dec 31, 2017
Study Type : Human Study
Additional Links
Substances : Lactobacillus reuteri
Diseases : Dental Caries
Pharmacological Actions : Antimicrobial
[+]

Tea inhibited the activity of salivary amylase.Feb 29, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2016 Mar ;10(3):ZC74-7. Epub 2016 Mar 1. PMID: 27135007
Article Published Date : Feb 29, 2016
Study Type : Human Study
Additional Links
Substances : Black Tea
Diseases : Dental Caries
Pharmacological Actions : Alpha-amylase inhibitor, Anti-Bacterial Agents
Additional Keywords : Risk Reduction
[+]

The 40-month consumption fo xylitol-containing chewing gums prevents aging-related increase of salivary Streptococcus mutans (cariogenic) bacteria.Jan 01, 1996

Pubmed Data : Caries Res. 1996;30(3):180-8. PMID: 8860027
Article Published Date : Jan 01, 1996
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries
[+]

The effectiveness of 0.5% C. sinensis extract was more compared to 0.05% sodium fluoride and 0.2% chlorhexidine gluconate mouth rinses.Apr 30, 2015

Pubmed Data : J Int Soc Prev Community Dent. 2015 May-Jun;5(3):218-26. PMID: 26236682
Article Published Date : Apr 30, 2015
Study Type : Human Study
Additional Links
Substances : Green Tea
Diseases : Dental Caries, Dental Caries: Children, Dental Plaque, Gingivitis
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Natural Substances Versus Drugs, Superiority of Natural Substances versus Drugs
Problem Substances : Chlorhexidine gluconate, Sodium Fluoride
[+]

The impact of photobiomodulation of major salivary glands on caries risk.Jul 18, 2019

Pubmed Data : Lasers Med Sci. 2019 Jul 19. Epub 2019 Jul 19. PMID: 31325124
Article Published Date : Jul 18, 2019
Study Type : Human Study
Additional Links
Diseases : Dental Caries, Steptococcus Mutans Infections
Therapeutic Actions : Laser Treatment: Low-Level
Pharmacological Actions : Antimicrobial
[+]

The maternal consumption of xylitol-chewing gum is associated with a lower rate of Streptococcus mutans colonization in offspring.Jan 01, 2010

Pubmed Data : J Dent Res. 2010 Jan;89(1):56-60. PMID: 19948944
Article Published Date : Jan 01, 2010
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Prenatal Nutrition: Health of the Offspring, Prenatal Nutrition: Prevention of Problems, Streptococcus Infections
Therapeutic Actions : Gum Chewing
[+]

The results of this study found that dental caries increased in children undergoing antineoplastic treatment.Jun 30, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Adv Clin Exp Med. 2016 Jul-Aug;25(1):11-9. PMID: 26935493
Article Published Date : Jun 30, 2016
Study Type : Human Study
Additional Links
Diseases : Dental Caries: Children
Additional Keywords : Increased Risk
Anti Therapeutic Actions : Chemotherapy
[+]

Tulsi has stood the test and is as effective as Chlorhexidine and Listerine in reducing the salivary S. mutans levels.Oct 31, 2011

Pubmed Data : Contemp Clin Trials. 2011 Nov ;32(6):802-8. Epub 2011 Jul 6. PMID: 21763461
Article Published Date : Oct 31, 2011
Study Type : Human Study
Additional Links
Substances : Holy Basil
Diseases : Dental Caries, Dental Plaque
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Mouthwash, Natural Substances Versus Drugs, Plant Extracts
Problem Substances : Chlorhexidine gluconate
[+]

Twice-daily use of a Licorice lollipop significantly reduced the number and percent of Streptococcus mutans in high-risk children. Dec 01, 2010

Pubmed Data : Eur Arch Paediatr Dent. 2010 Dec ;11(6):274-8. PMID: 21108917
Article Published Date : Dec 01, 2010
Study Type : Human Study
Additional Links
Substances : Licorice
Diseases : Dental Caries: Children, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Phytotherapy, Plant Extracts
[+]

Xylitol chewing gum suppresses Streptococcus mutans growth indicating it may prevent dental caries.Sep 01, 2003

Pubmed Data : Phytother Res. 2003 Sep;17(8):938-41. PMID: 10916329
Article Published Date : Sep 01, 2003
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Streptococcus Infections
Therapeutic Actions : Gum Chewing
[+]

Xylitol containing chewing gums have a beneficial effect on lactic acid production in dental plaque from caries active pre-school children.Jan 01, 2003

Pubmed Data : Oral Health Prev Dent. 2003;1(3):195-9. PMID: 15641497
Article Published Date : Jan 01, 2003
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Dental Caries: Children
[+]

Xylitol is more effective than sorbitol for preventing dental caries in adults.Feb 01, 1996

Pubmed Data : Int Dent J. 1996 Feb;46(1):22-34. PMID: 8744914
Article Published Date : Feb 01, 1996
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries
[+]

Xylitol syrup is effective in preventing early childhood caries. Jul 01, 2009

Pubmed Data : Arch Pediatr Adolesc Med. 2009 Jul;163(7):601-7. PMID: 19581542
Article Published Date : Jul 01, 2009
Study Type : Human Study
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Dental Caries: Children
[+]

Aloe vera gel at optimum concentration could be used as an antiseptic for prevention of dental caries and periodontal diseases. Jan 01, 2012

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Oral Sci. 2012 ;54(1):15-21. PMID: 22466882
Article Published Date : Jan 01, 2012
Study Type : Human In Vitro
Additional Links
Substances : Aloe Vera
Diseases : Dental Caries, Periodontal Diseases
Pharmacological Actions : Anti-Bacterial Agents
[+]

A combination of astaxanthin and fish oil supplementation alters antioxidant enzyme profile of dental pulp tissue.May 06, 2012

Pubmed Data : Int Endod J. 2012 May 7. Epub 2012 May 7. PMID: 22809098
Article Published Date : May 06, 2012
Study Type : Animal Study
Additional Links
Substances : Astaxanthin, Fish Oil
Diseases : Dental Caries, Dental Diseases, Oxidative Stress, Periodontal Diseases
Pharmacological Actions : Antioxidants
[+]

Cariogenic potential of commercial sweeteners in an experimental biofilm caries model on enamel.Aug 31, 2013

Pubmed Data : Arch Oral Biol. 2013 Sep ;58(9):1116-22. Epub 2013 Apr 28. PMID: 23631998
Article Published Date : Aug 31, 2013
Study Type : Animal Study
Additional Links
Diseases : Dental Caries
Problem Substances : Aspartame, Sucralose (aka Splenda), Sucrose
[+]

Cranberry proanthocyanidins reduced the formation of biofilms by S. mutans in vitro and dental caries development in vivo.Dec 31, 2009

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Caries Res. 2010 ;44(2):116-26. Epub 2010 Mar 16. PMID: 20234135
Article Published Date : Dec 31, 2009
Study Type : Animal Study
Additional Links
Substances : Cranberry, Cranberry Proanthocyanidins
Diseases : Dental Caries
Pharmacological Actions : Enzyme Inhibitors
Additional Keywords : Plant Extracts
[+]

Frequent intake of black tea can significantly decrease caries formation, even in the presence of sugars in the diet.Dec 31, 2002

Pubmed Data : Int J Food Sci Nutr. 2003 Jan ;54(1):89-95. PMID: 12701240
Article Published Date : Dec 31, 2002
Study Type : Animal Study
Additional Links
Substances : Black Tea
Diseases : Dental Caries
Additional Keywords : Plant Extracts
[+]

Fructose may contribute to worsening dental caries.Jan 01, 1990

Pubmed Data : Arch Oral Biol. 1990;35(10):839-44. PMID: 2124801
Article Published Date : Jan 01, 1990
Study Type : Animal Study
Additional Links
Diseases : Dental Caries
Problem Substances : Fructose, Sucrose
[+]

Natural antibacterial agents like tea tree oil and aloe vera could be effectively used as cavity disinfectants.Jun 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2017 Jul ;11(7):DC05-DC09. Epub 2017 Jul 1. PMID: 28892888
Article Published Date : Jun 30, 2017
Study Type : Animal Study
Additional Links
Substances : Aloe Vera, Tea Tree
Diseases : Dental Caries
Pharmacological Actions : Anti-Bacterial Agents
[+]

This review is an attempt to assess the antimicrobial efficacy of 10 plant extracts on dental caries and plaque microorganisms.Jun 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Pharmacogn Rev. 2015 Jul-Dec;9(18):87-92. PMID: 26392704
Article Published Date : Jun 30, 2015
Study Type : Review
Additional Links
Substances : Curry Leaves, Eucalyptus, Guava, Hibiscus sabdariffa , Holy Basil, Mangifera indica , Neem
Diseases : Dental Caries, Periodontal Diseases, Streptococcus Infections
Pharmacological Actions : Antimicrobial
[+]

Allicin may have therapeutic value for controlling oral pathogens.May 06, 2011

Pubmed Data : J Med Food. 2011 May 6. Epub 2011 May 6. PMID: 21548800
Article Published Date : May 06, 2011
Study Type : In Vitro Study
Additional Links
Substances : Allicin
Diseases : Dental Caries, Periodontal Diseases
Pharmacological Actions : Anti-Bacterial Agents
[+]

Baccharis dracunculifolia and propolis have anti-bacterial effects against the cariogenic factors of Streptococcus mutans. Nov 01, 2004

Pubmed Data : Biol Pharm Bull. 2004 Nov;27(11):1834-9. PMID: 15516733
Article Published Date : Nov 01, 2004
Study Type : In Vitro Study
Additional Links
Substances : Baccharis dracunculifolia, Bee Propolis
Diseases : Dental Caries, Steptococcus Mutans Infections
Additional Keywords : Plant Extracts
[+]

Berberine accelerates odontoblast differentiation by Wnt/β-catenin activation.Mar 31, 2019

Pubmed Data : Cell Reprogram. 2019 Apr ;21(2):108-114. PMID: 30969881
Article Published Date : Mar 31, 2019
Study Type : In Vitro Study
Additional Links
Substances : Berberine
Diseases : Dental Caries
Pharmacological Actions : Wnt/β-catenin signaling pathway modulation
[+]

C. incanus infusion reduced the initial bacterial colonization of enamel samples exposed to oral fluids for over eight hours.Nov 30, 2015

Pubmed Data : Planta Med. 2015 Dec ;81(18):1727-35. Epub 2015 Aug 20. PMID: 26291656
Article Published Date : Nov 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Polyphenols, Rock-rose
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Plant Extracts
[+]

Carvacrol and thymol isolated from O. vulgare L. exhibit good bactericidal and antibiofilm activity against S. mutans.Nov 30, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : AMB Express. 2017 Dec ;7(1):49. Epub 2017 Feb 23. PMID: 28233286
Article Published Date : Nov 30, 2017
Study Type : In Vitro Study
Additional Links
Substances : Carvacrol, Oregano, Thymol
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Cinnamon and sweet basil essential oils had impressive in vitro anti-cariogenic bacteria and anti-plaque effects.Aug 31, 2017

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Clin Diagn Res. 2017 Sep ;11(9):DC30-DC35. Epub 2017 Sep 1. PMID: 29207708
Article Published Date : Aug 31, 2017
Study Type : In Vitro Study
Additional Links
Substances : Basil: Sweet, Cinnamon
Diseases : Dental Caries, Dental Plaque, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Essential Oils
[+]

Cranberry polyphenols: Natural weapons against dental caries.Feb 28, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent J (Basel). 2019 Mar 1 ;7(1). Epub 2019 Mar 1. PMID: 30823634
Article Published Date : Feb 28, 2019
Study Type : Review
Additional Links
Substances : Cranberry
Diseases : Dental Caries
Pharmacological Actions : Anti-Bacterial Agents
[+]

Crude whole apple extract has considerable anti-cariogenic effect on S. mutans.Mar 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Indian Soc Pedod Prev Dent. 2018 Apr-Jun;36(2):135-141. PMID: 29970630
Article Published Date : Mar 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : Apple
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Plant Extracts
[+]

Curcumin is an S. mutans sortase A inhibitor and has promising anti-caries characteristics through an anti-adhesion-mediated mechanism.Sep 30, 2013

Pubmed Data : Arch Oral Biol. 2013 Oct ;58(10):1343-8. Epub 2013 Jun 16. PMID: 23778072
Article Published Date : Sep 30, 2013
Study Type : In Vitro Study
Additional Links
Substances : Curcumin
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
[+]

Effect of prebiotics-enhanced probiotics on the growth of Streptococcus mutans.Dec 31, 2018

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Microbiol. 2019 ;2019:4623807. Epub 2019 Aug 1. PMID: 31467551
Article Published Date : Dec 31, 2018
Study Type : In Vitro Study
Additional Links
Substances : FOS (Fructooligosaccharides), Galactooligosaccharides, Prebiotics, Probiotics
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
[+]

Garlic inhibits multidrug resistant Streptococcus mutans. Oct 01, 2007

Pubmed Data : J Indian Soc Pedod Prev Dent. 2007 Oct-Dec;25(4):164-8. PMID: 18007101
Article Published Date : Oct 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Garlic
Diseases : Bacterial Infections: Resistance/Biofilm Formation, Dental Caries, Peridontal Infection, Steptococcus Mutans Infections
Additional Keywords : Multi-Drug Resistant Pathogens
[+]

Ginsenoside Rh2 may serve as an alternative agent to prevent dental caries.Dec 16, 2018

Pubmed Data : J Appl Microbiol. 2018 Dec 17. Epub 2018 Dec 17. PMID: 30556937
Article Published Date : Dec 16, 2018
Study Type : In Vitro Study
Additional Links
Substances : Ginsenosides
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

Grape seed extract remineralizes artificial root caries in vitro. Jan 01, 2005

Pubmed Data : Indian J Physiol Pharmacol. 2005 Jan;49(1):111-4. PMID: 18819742
Article Published Date : Jan 01, 2005
Study Type : In Vitro Study
Additional Links
Substances : Grape Seed Extract
Diseases : Dental Caries
Additional Keywords : Remineralization of Root Caries
[+]

Magnolol may be a candidate for prevention and management of dental caries. Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Microbiol Immunol. 2016 Jan ;60(1):10-6. PMID: 26600203
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Substances : Magnolia, Magnolol
Diseases : Dental Caries, Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents, Antimicrobial
Additional Keywords : Biofilm
[+]

Mango and neem tree extracts inhibit four organisms associated with dental caries. Oct 01, 2007

Pubmed Data : Indian J Dent Res. 2007 Oct-Dec;18(4):148-51. PMID: 17938488
Article Published Date : Oct 01, 2007
Study Type : In Vitro Study
Additional Links
Substances : Mango , Neem
Diseases : Dental Caries, Steptococcus Mutans Infections
[+]

Many antibiotics presented high concentration of sugars, high titratable acidity, pH below the critical value and high viscosity.Dec 31, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Open Dent J. 2016 ;10:420-30. Epub 2016 Aug 22. PMID: 27583053
Article Published Date : Dec 31, 2015
Study Type : In Vitro Study
Additional Links
Diseases : Dental Caries, Dental Enamel Defects
Additional Keywords : Risk Factors
Problem Substances : Antibiotics
[+]

Ocimum sanctum leaf extract demonstrated antimicrobial activity against microorganisms responsible for dental cariesApr 30, 2015

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Int J Clin Pediatr Dent. 2015 May-Aug;8(2):99-101. Epub 2015 Aug 11. PMID: 26379375
Article Published Date : Apr 30, 2015
Study Type : In Vitro Study
Additional Links
Substances : Holy Basil
Diseases : Dental Caries, Streptococcus Infections
Pharmacological Actions : Antimicrobial
[+]

Peppermint and rosemary extract are superior to the chemical chlorhexidine in preventing dental biofilm formation.Sep 01, 2008

Pubmed Data : Phytother Res. 2008 Sep;22(9):1162-7. PMID: 18729251
Article Published Date : Sep 01, 2008
Study Type : In Vitro Study
Additional Links
Substances : Peppermint, Rosemary
Diseases : Dental Caries
Additional Keywords : Plant Extracts, Superiority of Natural Substances versus Drugs
[+]

Peppermint and to a lesser extent cumin essential oil compare favorably to the chemical chlorhexidine as anti-gingival dental plaque agents.Mar 20, 2008

Pubmed Data : Nat Prod Res. 2008 Mar 20;22(5):428-39. PMID: 18404563
Article Published Date : Mar 20, 2008
Study Type : In Vitro Study
Additional Links
Substances : Cumin, Peppermint
Diseases : Dental Caries, Gingivitis
Additional Keywords : Superiority of Natural Substances versus Drugs
[+]

Phyllanthus muellerianus exhibits antimicrobial properties. Apr 04, 2011

Pubmed Data : J Ethnopharmacol. 2011 Apr 4. Epub 2011 Apr 4. PMID: 21470574
Article Published Date : Apr 04, 2011
Study Type : In Vitro Study
Additional Links
Substances : Phyllanthus Muellerianus
Diseases : Clostridium Infections, Clostridium Sporogenes, Dental Caries, Steptococcal Infections, Streptococcus pyogenes, Tetanus
Pharmacological Actions : Antimicrobial
Additional Keywords : Science Confirms Tradition
[+]

Phytochemicals naturally synthesized by M. citrifolia have an inhibitory effect on oral streptococci.Oct 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : J Dent (Tehran). 2014 Nov ;11(6):703-10. Epub 2014 Nov 30. PMID: 25628701
Article Published Date : Oct 31, 2014
Study Type : In Vitro Study
Additional Links
Substances : Noni
Diseases : Dental Caries, Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
[+]

Polyphenols inhibit Candida albicans and Streptococcus mutans biofilm formation.Apr 10, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Dent J (Basel). 2019 Apr 11 ;7(2). Epub 2019 Apr 11. PMID: 30978919
Article Published Date : Apr 10, 2019
Study Type : In Vitro Study
Additional Links
Substances : Green Tea, Polyphenols
Diseases : Candida Albicans, Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation
[+]

Pomegranate extracts have the potential to prevent dental caries.Jun 24, 2016

Pubmed Data : Microb Pathog. 2016 Jun 25. Epub 2016 Jun 25. PMID: 27354207
Article Published Date : Jun 24, 2016
Study Type : In Vitro Study
Additional Links
Substances : Pomegranate Peel
Diseases : Dental Caries, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm, Plant Extracts
[+]

Probiotics may have value as oral health biotherapeutics.Jun 12, 2012

Pubmed Data : Expert Opin Biol Ther. 2012 Jun 13. Epub 2012 Jun 13. PMID: 22690730
Article Published Date : Jun 12, 2012
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Dental Caries, Gingivitis, Periodontal Diseases, Periodontitis
Additional Keywords : Probiotics-oral Health
[+]

Regular and prolonged use of xylitol chewing gum may have a caries-preventive effect.Apr 01, 1994

Pubmed Data : Acta Odontol Scand. 1994 Apr;52(2):116-27. PMID: 8048322
Article Published Date : Apr 01, 1994
Study Type : Review
Additional Links
Substances : Xylitol
Diseases : Dental Caries
[+]

Review: Probiotics and oral health.May 24, 2012

Pubmed Data : Curr Pharm Des. 2012 May 25. Epub 2012 May 25. PMID: 22632388
Article Published Date : May 24, 2012
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Dental Caries
Additional Keywords : Probiotics-oral Health
[+]

Stevia has potential in the prevention of dental caries.Mar 31, 2016

Pubmed Data : Am J Dent. 2016 Apr ;29(2):87-92. PMID: 27295866
Article Published Date : Mar 31, 2016
Study Type : In Vitro Study
Additional Links
Substances : Stevia
Diseases : Dental Caries, Dental Plaque, Steptococcus Mutans Infections
Pharmacological Actions : Antimicrobial
[+]

Tea protects against dental caries.Jun 01, 1998

Pubmed Data : Arch Pharm Res. 1998 Jun;21(3):348-52. PMID: 9875456
Article Published Date : Jun 01, 1998
Study Type : In Vitro Study
Additional Links
Substances : Tea
Diseases : Dental Caries
Pharmacological Actions : Anti-Bacterial Agents
[+]

Thai herbal formula were evaluated for their ability to be used as a remedy for dental caries.Apr 09, 2012

Pubmed Data : Pharm Biol. 2012 Apr 10. Epub 2012 Apr 10. PMID: 22489572
Article Published Date : Apr 09, 2012
Study Type : Bacterial
Additional Links
Substances : Thai Herbal Formulations
Diseases : Dental Caries
Additional Keywords : Dental Caries, Medicinal Plants, Thai
[+]

The habitual use of xylitol can be associated with significant reduction in caries incidence and with tooth remineralization.Jan 01, 2010

Pubmed Data : Int J Dent. 2010;2010:981072. Epub 2010 Jan 5. PMID: 20339492
Article Published Date : Jan 01, 2010
Study Type : Review
Additional Links
Substances : Xylitol
Diseases : Dental Caries
[+]

The use of xylitol containing chewing gum prevents dental caries. Jan 01, 2009

Pubmed Data : Evid Based Dent. 2009;10(1):10-1. PMID: 19322219
Article Published Date : Jan 01, 2009
Study Type : Review
Additional Links
Substances : Xylitol
Diseases : Dental Caries
[+]

There is very little contemporary evidence, meeting the review's inclusion criteria, that has evaluated the effectiveness of water fluoridation for the prevention of caries.Dec 31, 2014

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Cochrane Database Syst Rev. 2015 ;6:CD010856. Epub 2015 Jun 18. PMID: 26092033
Article Published Date : Dec 31, 2014
Study Type : Review
Additional Links
Diseases : Dental Caries, Dental Caries: Children, Dental Fluorosis
Additional Keywords : Water Fluoridation
Problem Substances : Sodium Fluoride
[+]

This in vitro study demonstrated that violet-blue light has the capacity to inhibit S. mutans biofilm formation. Aug 31, 2016

Pubmed Data : Curr Microbiol. 2016 Sep ;73(3):426-33. Epub 2016 Aug 8. PMID: 27278805
Article Published Date : Aug 31, 2016
Study Type : In Vitro Study
Additional Links
Diseases : Dental Caries, Steptococcus Mutans Infections
Therapeutic Actions : Light Therapy
Pharmacological Actions : Antimicrobial
Additional Keywords : Biofilm
[+]

This indicates that polyphenol-rich lingonberry fraction offers a promising natural food derivative for prevention of dental caries.Feb 27, 2019

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Bull Tokyo Dent Coll. 2019 Feb 28 ;60(1):1-9. Epub 2019 Jan 31. PMID: 30700643
Article Published Date : Feb 27, 2019
Study Type : In Vitro Study
Additional Links
Substances : Lingonberry
Diseases : Dental Caries, Steptococcus Mutans Infections, Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation, Plant Extracts
[+]

This review has focused on several beneficial properties of probiotics.Jul 31, 2016

Article Publish Status : This is a free article. Click here to read the complete article.
Pubmed Data : Trop Life Sci Res. 2016 Aug ;27(2):73-90. PMID: 27688852
Article Published Date : Jul 31, 2016
Study Type : Review
Additional Links
Substances : Probiotics
Diseases : Anxiety, Dental Caries, Depression, Gastrointestinal Diseases, Periodontal Diseases
Pharmacological Actions : Anticholesteremic Agents, Immunomodulatory, Nitric Oxide Inhibitor
[+]

Triphala can be effectively used to manage dental caries, gingival and periodontal diseases.May 11, 2015

Pubmed Data : Infect Disord Drug Targets. 2015 May 12. Epub 2015 May 12. PMID: 25966965
Article Published Date : May 11, 2015
Study Type : Review
Additional Links
Substances : Triphala
Diseases : Dental Caries, Dental Caries: Children, Gingivitis, Periodontal Diseases
Pharmacological Actions : Antimicrobial
[+]

Xylitol has a beneficial action on mutans streptococci and dental plaque.Jan 25, 2008

Pubmed Data : Subst Abuse Treat Prev Policy. 2008 Jan 25;3:1. PMID: 7607748
Article Published Date : Jan 25, 2008
Study Type : Review
Additional Links
Substances : Xylitol
Diseases : Dental Caries, Streptococcus Infections
Pharmacological Actions : Anti-Bacterial Agents

Copyright: bastetamon / 123RF Stock Photo

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