Treatment of Nonclassic 11-Hydroxylase deficiency with Ashwagandha root. - GreenMedInfo Summary
Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root.
Case Rep Endocrinol. 2017 ;2017:1869560. Epub 2017 Jun 20. PMID: 28713602
An elderly woman presented with acne and male pattern alopecia, which upon diagnostic evaluation was found to be due to nonclassic 11-hydroxylase deficiency. We previously reported that Ashwagandha root ameliorates nonclassic 3-β-ol dehydrogenase and aldosterone synthase deficiencies. This is the first report of its use being associated with amelioration of nonclassic 11-hydroxylase deficiency, where its apparent effects appear to be dose-related.