Efficacy of Medical Cannabis for Treatment of Refractory Epilepsy in Children and Adolescents with Emphasis on the Israeli Experience.
Isr Med Assoc J. 2017 Feb ;19(2):76-78. PMID: 28457054
Approximately 25% of subjects with epilepsy are pharmacologically resistant, defined as the failure to arrest seizures after an adequate trial of at least two appropriate medications . Second-line therapeutic options are then introduced, but in most cases these have only partial efficacy , hence the need for additional treatment options. There is now concrete evidence to suggest the efficacy of cannabis in the treatment of epilepsy, particularly in the refractory group.