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Abstract Title:

Strawberries, Blueberries, and Cranberries in the Metabolic Syndrome: Clinical Perspectives.

Abstract Source:

J Agric Food Chem. 2011 Nov 29. Epub 2011 Nov 29. PMID: 22082311

Abstract Author(s):

Arpita Basu, Timothy J Lyons

Article Affiliation:

Nutritional Sciences, 301 Human Sciences, Oklahoma State University , Stillwater, Oklahoma 74078-6141, United States.

Abstract:

Emerging science supports therapeutic roles of strawberries, blueberries, and cranberries in metabolic syndrome, a prediabetic state characterized by several cardiovascular risk factors. Interventional studies reported by our group and others have demonstrated the following effects: strawberries lowering total and LDL-cholesterol, but not triglycerides, and decreasing surrogate biomarkers of atherosclerosis (malondialdehyde and adhesion molecules); blueberries lowering systolic and diastolic blood pressure and lipid oxidation and improving insulin resistance; and low-calorie cranberry juice selectively decreasing biomarkers of lipid oxidation (oxidized LDL) and inflammation (adhesion molecules) in metabolic syndrome. Mechanistic studies further explain these observations as up-regulation of endothelial nitric oxide synthase activity, reduction in renal oxidative damage, and inhibition of the activity of carbohydrate digestive enzymes or angiotensin-converting enzyme by these berries. These findings need confirmation in future studies with a focus on the effects of strawberry, blueberry, or cranberry intervention in clinical biomarkers and molecular mechanisms underlying the metabolic syndrome.

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Sayer Ji
Founder of GreenMedInfo.com

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