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Abstract Title:

Why statin therapy may increase the risk for posttransplantation squamous cell carcinoma.

Abstract Source:

Transpl Immunol. 2010 Aug ;23(4):224-5. Epub 2010 Jun 17. PMID: 20591670

Abstract Author(s):

Luca Mascitelli, Francesca Pezzetta, Mark R Goldstein

Article Affiliation:

Comando Brigata Alpina Julia, Medical Service, 8 Via S. Agostino, Udine, 33100, Italy. lumasci@libero.it

Abstract:

We suggest that surveillance for squamous cell cancer might be particularly useful for transplant patients receiving statin therapy. We recommend that development of non melanoma skin cancer should be specified as a secondary endpoint in future large endpoint statin trials, and suggest that in transplant patients the adverse effects of statin drugs may outweigh benefits, especially in women and the elderly, a subset of population in which even individuals at high risk for cardiovascular disease have shown no trend to net benefit from statins.

Study Type : Commentary

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Sayer Ji
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