Royal jelly inhibits the estrogenic and proliferative effect of Bisphenol-A. - GreenMedInfo Summary
Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells.
Biosci Biotechnol Biochem. 2007 Jan;71(1):253-5. Epub 2007 Jan 7. PMID:17213647
Royal jelly is known as a functional food containing many useful minerals. In this study, we found an anti-environmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.