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Article Publish Status: FREE
Abstract Title:

Protective effects of panax notoginseng saponins on cardiovascular diseases: a comprehensive overview of experimental studies.

Abstract Source:

Evid Based Complement Alternat Med. 2014 ;2014:204840. Epub 2014 Jul 24. PMID: 25152758

Abstract Author(s):

Xiaochen Yang, Xingjiang Xiong, Heran Wang, Jie Wang

Article Affiliation:

Xiaochen Yang

Abstract:

Panax notoginseng saponins (PNS) are one of the most important compounds derived from roots of the herb Panax notoginseng which are traditionally used as a hemostatic medicine to control internal and external bleeding in China for thousands of years. To date, at least twenty saponins were identified and some of them including notoginsenoside R1, ginsenoside Rb1, and ginsenoside Rg1 were researched frequently in the area of cardiovascular protection. However, the protective effects of PNS on cardiovascular diseases based on experimental studies and its underlying mechanisms have not been reviewed systematically. This paper reviewed the pharmacology of PNS and its monomers Rb1, Rg1, and R1 in the treatment for cardiovascular diseases.

Study Type : Review

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Sayer Ji
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