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Abstract Title:

[Protection of puerarin on the cerebral injury in the rats with acute local ischemia].

Abstract Source:

Zhongguo Zhong Yao Za Zhi. 2005 Mar ;30(6):457-9. PMID: 15810455

Abstract Author(s):

Hong-Ping Pan, Jia-Zhen Yang, Xiang-Lan Mo, Lu-Li Li, Zhen-Lu Huang, Jing Ye, Jin Huang

Article Affiliation:

Hong-Ping Pan

Abstract:

OBJECTIVE: To study the protection of puerarin on the cerebral injury in the rats with acute local ischemia.

METHOD: Rat was evaluated model of acute local cerebral ischemia was made by ligating middle cerebral artery. The cerebral damage toxylin and eosin((HE).

RESULT: The number of died neurons were significantly less in puerarin-treated rats than in the rats with cerebral ischemia (P<0. 05). Similarly, the cerebral edema were significantly attenuated in the puerarin-treated rats as compared with cerebrally ischemic rats.

CONCLUSION: Puerarin can prevent the neuron from damage induced by acute cerebral ischemia.

Study Type : Animal Study

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