An unexpected inverse relationship between HbA1c levels and mortality in patients with diabetes and advanced systolic heart failure.
Am Heart J. 2006 Jan;151(1):91. PMID: 16368297
Cedars Sinai Medical Center, Los Angeles, CA, USA.
BACKGROUND: In diabetes, poor glycemic control, as indexed by hemoglobin A1c (HbA1c), is associated with increased risk of cardiovascular events and new-onset heart failure (HF). However, in patients with diabetes and HF, the relationship between glucose control and survival has not been investigated. Our study aimed to evaluate the relationship between HbA1c levels and mortality in patients with diabetes and advanced systolic HF. METHODS: We studied a cohort of 123 patients with diabetes and advanced systolic HF referred to a single center with HbA1c values measured at presentation. The patients were grouped based on HbA1c: HbA1c