This paper reviewed major progresses of tanshinone IIA in antiatherosclerosis research. - GreenMedInfo Summary
Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis.
Evid Based Complement Alternat Med. 2014 ;2014:267976. Epub 2014 Dec 2. PMID: 25525444
Tanshinone IIA (Tan II A) is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper reviewed major progresses of Tan IIA in antiatherosclerosis research, including immune cells, antigens, cytokines, and cell signaling pathways.