Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

n/a
Abstract Title:

Nephroprotective and antioxidant effect of green tea (Camellia sinensis) against nicotine-induced nephrotoxicity in rats and characterization of its bioactive compounds by HPLC-DAD.

Abstract Source:

Appl Physiol Nutr Metab. 2019 Feb 25. Epub 2019 Feb 25. PMID: 30802143

Abstract Author(s):

Anouar Ben Saad, Sana Ncib, Ilhem Rjeibi, Issam Saidi, Nacim Zouari

Article Affiliation:

Anouar Ben Saad

Abstract:

Nicotine (NT) is a potential inducer of oxidative stress, through which it can damage numerous biological molecules. Natural antioxidants that prevent or slow the progression and severity of nicotine toxicity may have a significant health impact. The purpose of this study, conducted on Wistar rats, was to evaluate the beneficial effects of green tea (Camellia sinensis) extract on nicotine treatment induced damage on kidney. Our results showed that nicotine significantly (p<0.01) increased serum and kidney malondialdehyde (MDA), the serum contents of urea, creatinine and uric acid. In addition, nicotine intoxication significantly (p<0.01) decreased the vitamin E and C levels in serum and kidney tissue as well as the activities of SOD, CAT and GPx. Interestingly, animals that were pretreated with green tea, prior to nicotine-administration, showed a significant nephroprotection, revealed by a significant reduction-induced oxidative damage for all tested markers. The nephroprotective activity of green tea is mediated, at least in part, by the antioxidant effect of its constituents.

Study Type : Animal Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2019 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.