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Article Publish Status: FREE
Abstract Title:

The Protective Effects of Nigella sativa and Its Constituents on Induced Neurotoxicity.

Abstract Source:

J Toxicol. 2015;2015:841823. Epub 2015 Oct 29. PMID: 26604923

Abstract Author(s):

Mohammad Reza Khazdair

Article Affiliation:

Mohammad Reza Khazdair

Abstract:

Nigella sativa (N. sativa) is an annual plant and widely used as medicinal plant throughout the world. The seeds of the plant have been used traditionally in various disorders and as a spice to ranges of Persian foods. N. sativa has therapeutic effects on tracheal responsiveness (TR) and lung inflammation on induced toxicity by Sulfur mustard. N. sativa has been widely used in treatment of various nervous system disorders such as Alzheimer disease, epilepsy, and neurotoxicity. Most of the therapeutic properties of this plant are due to the presence of some phenolic compounds especially thymoquinone (TQ), which is major bioactive component of the essential oil. The present review is an effort to provide a comprehensive study of the literature on scientific researches of pharmacological activities of the seeds of this plant on induced neurotoxicity.

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Sayer Ji
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