Susceptibility Assessment of Methicillin-ResistantStrains toExtract.
Dose Response. 2019 Apr-Jun;17(2):1559325819850425. Epub 2019 May 20. PMID: 31191184
Amna A Saddiq
Many plant-derived compounds have been used to treat microbial infections.a common cause of many organ infections, has generated increasing concern due to its resistance to antibacterial drugs. This work was carried out to explore the susceptibility of 6 strains (LN872136, LN872137, LN871238, LN871239, LN872140, and LN871241) of methicillin-resistantto aqueous extract ofseeds in vitro. Various concentrations (5-20 mg/mL) were used to evaluate the effect of the extract on bacteria growth via the assessment of the microbial biomass and the inhibition zone (IZ). The results showed that the plant extract at 15 or 20 mg/mL, significantly decreased the the biomass ofstrains after 24 or 48 hours exposure period.(LN871241) showed the largest IZ at 20 mg/mL and documented by scanning electron microscope. The current work may suggest thatseed extract can be candidate as a promising antimicrobial agent to treat infection with methicillin-resistant.