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Abstract Title:

Hepatoprotective phenylethanoid glycosides from Cirsium setosum.

Abstract Source:

Nat Prod Res. 2016 Aug ;30(16):1824-9. Epub 2015 Sep 11. PMID: 26358803

Abstract Author(s):

Qinge Ma, Yongming Guo, Baomin Luo, Wenmin Liu, Rongrui Wei, Chunxia Yang, Chenghua Ding, Xuefeng Xu, Minghui He

Article Affiliation:

Qinge Ma

Abstract:

Two new phenylethanoid glycosides, namelyβ-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1) and β-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(4-hydroxyphenyl)-8-propenoate] (2), together with six phenylethanoid glycosides were isolated from Cirsium setosum. Their structures were elucidated by their spectroscopic data and references. Compounds 2, 4, 5, 7 and 8 (10 μM) exhibited moderate hepatoprotective activities. Compounds (3-8) were obtained from this plant for the first time.

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Hepatoprotective : CK(3182) : AC(1418)

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