Effects of Psilocybe argentipes on marble-burying behavior in mice.
Biosci Biotechnol Biochem. 2009 Aug;73(8):1866-8. Epub 2009 Aug 7. PMID: 19661714
Department of Health and Nutrition, Takasaki University of Health and Welfare, Gunma, Japan.
Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy.