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Abstract Title:

Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease.

Abstract Source:

Pediatr Pulmonol. 2010 Oct 21. Epub 2010 Oct 21. PMID: 20967850

Abstract Author(s):

Gulshan R Sethi, Kamal K Singhal, Amarender S Puri, Mukta Mantan

Article Affiliation:

Department of Pediatrics, Lok Nayak Hospital, New Delhi, India.

Abstract:

Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of the pulmonary symptoms along with improvement of anthropometric parameters and hemoglobin over a short-term follow-up period of 8-17 months. Inhaled/oral steroids and immunosuppressants could be weaned off after dietary exclusion therapy in each of the three children. Gluten free diet should be instituted in all patients diagnosed with Lane-Hamilton syndrome. It ameliorates both the pulmonary as well as the intestinal symptoms although the precise mechanism of the pulmonary response is as yet unclear. Pediatr Pulmonol.© 2010 Wiley-Liss, Inc.

Study Type : Human Study

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Sayer Ji
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