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Abstract Title:

Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro.

Abstract Source:

Mutat Res. 2005 Jun 6 ;583(2):178-83. PMID: 15869902

Abstract Author(s):

Elisabeth Diem, Claudia Schwarz, Franz Adlkofer, Oswald Jahn, Hugo Rüdiger

Article Affiliation:

Elisabeth Diem

Abstract:

Cultured human diploid fibroblasts and cultured rat granulosa cells were exposed to intermittent and continuous radiofrequency electromagnetic fields (RF-EMF) used in mobile phones, with different specific absorption rates (SAR) and different mobile-phone modulations. DNA strand breaks were determined by means of the alkaline and neutral comet assay. RF-EMF exposure (1800 MHz; SAR 1.2 or 2 W/kg; different modulations; during 4, 16 and 24h; intermittent 5 min on/10 min off or continuous wave) induced DNA single- and double-strand breaks. Effects occurred after 16 h exposure in both cell types and after different mobile-phone modulations. The intermittent exposure showed a stronger effect in the comet assay than continuous exposure. Therefore we conclude that the induced DNA damage cannot be based on thermal effects.

Study Type : Human In Vitro

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Sayer Ji
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