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Abstract Title:

Exosomes in inflammation and inflammatory disease.

Abstract Source:

Proteomics. 2019 Feb 13:e1800149. Epub 2019 Feb 13. PMID: 30758141

Abstract Author(s):

Brandon Dow Chan, Wing-Yan Wong, Magnolia Muk-Lan Lee, William Chi-Shing Cho, Benjamin K Yee, Yiu Wa Kwan, William Chi-Shing Tai

Article Affiliation:

Brandon Dow Chan

Abstract:

Exosomes are a subset of extracellular vesicles released by all cell types and involved in local and systemic intercellular communication. In the past decade, research into exosomes has swelled as their important role in the mediation of health and disease has been increasingly established and acknowledged. Exosomes carry a diverse range of cargo including proteins, nucleic acids and lipids derived from their parental cell that, when delivered to the recipient cell, can confer pathogenic or therapeutic effects through modulation of immunity and inflammation. In this review, we will discuss of the role of exosomes on mediation of immune and inflammatory responses, and their participation in diseases with a significant inflammatory component. The considerable potential for exosomes in therapy and diagnosis of inflammatory diseases will also be highlighted. This article is protected by copyright. All rights reserved.

Study Type : Review
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Additional Keywords : Exosomes : CK(35) : AC(10)

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Sayer Ji
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