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Article Publish Status: FREE
Abstract Title:

Vitamin D and Atopic Dermatitis in Childhood.

Abstract Source:

J Immunol Res. 2015;2015:257879. Epub 2015 Apr 20. PMID: 25973433

Abstract Author(s):

Michelangelo Vestita, Angela Filoni, Maurizio Congedo, Caterina Foti, Domenico Bonamonte

Article Affiliation:

Michelangelo Vestita

Abstract:

Vitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases. A wealth of studies describing a beneficial effect of vitamin D on atopic dermatitis (AD) prevalence and severity are known. However, observations linking high vitamin D levels to an increased risk of developing AD have also been published, effectively creating a controversy. In this paper, we review the existing literature on the association between AD and vitamin D levels, focusing on childhood. As of today, the role of vitamin D in AD is far from clear; additional studies are particularly needed in order to confirm the promising therapeutic role of vitamin D supplementation in childhood AD.

Study Type : Review

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Sayer Ji
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