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Abstract Title:

Effects of Embelin on Lipid Peroxidation and Free Radical Scavenging Activity against Liver Damage in Rats.

Abstract Source:

Basic Clin Pharmacol Toxicol. 2009 May 26. Epub 2009 May 26. PMID: 19496777

Abstract Author(s):

Dharmendra Singh, Ruchi Singh, Pahup Singh, Radhey S Gupta

Abstract:

The study aimed to evaluate the hepatic antioxidant capacity of embelin (from Embelia ribes) using different antioxidant tests, free radical scavenging activity and lipid peroxidation in albino rats. Carbon tetrachloride (CCl(4)) treatment to rats has been more susceptible to peroxidative damage through production of reactive metabolites, namely trichloromethyl-free radicals ( and/or ) as measured by thiobarbituric acid reactive species. After the induction of liver damage by CCl(4) intoxication to rats, the concentration of lipid peroxidation was significantly (P

Study Type : Animal Study

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