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Abstract Title:

Caffeinated and decaffeinated coffee consumption and risk of all-cause mortality: a dose-response meta-analysis of cohort studies.

Abstract Source:

J Hum Nutr Diet. 2019 Jun ;32(3):279-287. Epub 2019 Feb 20. PMID: 30786114

Abstract Author(s):

Q Li, Y Liu, X Sun, Z Yin, H Li, C Cheng, L Liu, R Zhang, F Liu, Q Zhou, C Wang, L Li, B Wang, Y Zhao, M Zhang, D Hu

Article Affiliation:

Q Li

Abstract:

BACKGROUND: Previous meta-analysis showed an inverse association between coffee consumption and all-cause mortality. However, the relationship between caffeinated and decaffeinated coffee consumption and all-cause mortality is inconsistent. We aimed to identify and review the published evidence updating the association between coffee consumption and all-cause mortality and, furthermore, to investigate the association of caffeinated and decaffeinated coffee consumption and all-cause mortality.

METHODS: We systematically searched PubMed and Web of Science for studies published up to 9 November 2017. Cohort studies in which authors reported relative risks (RRs) of all-cause mortality for at least three levels of coffee consumption were eligible. Random-effects models were used to estimate the pooled RR of all-cause mortality with coffee consumption. Restricted cubic splines were used to model the dose-response association.

RESULTS: We included 21 cohort study articles (10 103 115 study participants and 240 303 deaths). We found a nonlinear association between coffee consumption and all-cause mortality (P < 0.001). Compared with no or rare coffee consumption, with a consumption of 3 cups day, the risk of all-cause mortality might reduce 13% (RR = 0.87; 95% confidence interval = 0.84-0.89).

CONCLUSIONS: The findings of the present study provide quantitative data suggesting that coffee consumption plays a role in reducing the risk of all-cause mortality. Similar inverse associations are found for caffeinated coffee and decaffeinated coffee.

Study Type : Meta Analysis

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Sayer Ji
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