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Abstract Title:

Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn.

Abstract Source:

J Ethnopharmacol. 2004 Nov;95(1):83-5. PMID: 15374611

Abstract Author(s):

James B Perianayagam, S K Sharma, Aney Joseph, A J M Christina

Abstract:

The present study was designed to investigate the anti-pyretic and analgesic activity of ethanol (EEO) and aqueous (AEO) extracts of Emblica officinalis fruits in several experimental models. A single oral dose of EEO and AEO (500 mg/kg, i.p.) showed significant reduction in brewer's yeast induced hyperthermia in rats. EEO and AEO also elicited pronounced inhibitory effect on acetic acid-induced writhing response in mice in the analgesic test. Both, EEO and AEO did not show any significant analgesic activity in the tail-immersion test. These findings suggest that extracts of Emblica officinalis fruits possessed potent anti-pyretic and analgesic activity. Preliminary phytochemical screening of the extracts showed the presence of alkaloids, tannins, phenolic compounds, carbohydrates and amino acids, which may be responsible for anti-pyretic and analgesic activities.

Study Type : Animal Study

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Sayer Ji
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